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ONTOLOGY REPORT - ANNOTATIONS


Term:histone H3K9me2/H3K9me3 demethylase activity
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Accession:GO:0140684 term browser browse the term
Definition:Catalysis of the removal of a methyl group from a tri or a dimethyl-lysine residue at position 9 of the histone H3 protein. This is a dioxygenase reaction that is dependent on Fe(II) and 2-oxoglutarate.
Synonyms:exact_synonym: histone H3-tri/dimethyl-lysine-9 demethylase activity
 broad_synonym: histone H3K9me2 demethylase activity
 related_synonym: histone H3K9me3 demethylase activity
 xref: EC:1.14.11.66;   RHEA:60200



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histone H3K9me2/H3K9me3 demethylase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Kdm1a lysine demethylase 1A enables ISO (PMID:20833138) RGD PMID:20833138 NCBI chr 5:148,782,976...148,838,319
Ensembl chr 5:148,782,976...148,838,319
JBrowse link
G Kdm4a lysine demethylase 4A enables ISO (PMID:21914792) RGD PMID:21914792 NCBI chr 5:131,672,754...131,719,534
Ensembl chr 5:131,672,754...131,719,501
JBrowse link
G Kdm4b lysine demethylase 4B enables ISO (PMID:21914792) RGD PMID:21914792 NCBI chr 9:1,158,737...1,237,233
Ensembl chr 9:1,158,752...1,236,543
JBrowse link
G Kdm4c lysine demethylase 4C enables ISO (PMID:17277772), (PMID:21914792) RGD PMID:17277772 PMID:21914792 NCBI chr 5:88,100,710...88,306,821
Ensembl chr 5:88,100,733...88,306,818
JBrowse link
G Kdm4d lysine demethylase 4D enables ISO (PMID:21914792) RGD PMID:21914792 NCBI chr 8:11,279,756...11,304,920
Ensembl chr 8:11,268,859...11,305,290
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  molecular_function 21088
    catalytic activity 6122
      oxidoreductase activity 868
        dioxygenase activity 100
          2-oxoglutarate-dependent dioxygenase activity 64
            histone H3K9me2/H3K9me3 demethylase activity 5
Path 2
Term Annotations click to browse term
  molecular_function 21088
    catalytic activity 6122
      demethylase activity 42
        protein demethylase activity 30
          histone demethylase activity 30
            histone H3 demethylase activity 26
              histone H3K9 demethylase activity 12
                histone H3K9me2/H3K9me3 demethylase activity 5
paths to the root