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ONTOLOGY REPORT - ANNOTATIONS

Term:histone H3K deacetylase activity
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Accession:GO:0141050 term browser browse the term
Definition:Catalysis of the reaction: histone H3 N6-acetyl-L-lysine + H2O = histone H3 L-lysine + acetate. This reaction represents the removal of an acetyl group from a histone H3.


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histone H3K deacetylase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Sirt1 sirtuin 1 enables ISO (PMID:20027304) RGD PMID:20027304 NCBI chr20:25,307,225...25,329,273
Ensembl chr20:25,306,917...25,329,260 		JBrowse link
histone H3K14 deacetylase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hdac9 histone deacetylase 9 enables ISO (MGI:5287924|PMID:21708950) RGD PMID:21708950 MGI:5287924 NCBI chr 6:50,762,074...51,624,311
Ensembl chr 6:50,763,590...51,625,333 		JBrowse link
histone H3K9 deacetylase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hdac9 histone deacetylase 9 enables ISO (MGI:5287924|PMID:21708950) RGD PMID:21708950 MGI:5287924 NCBI chr 6:50,762,074...51,624,311
Ensembl chr 6:50,763,590...51,625,333 		JBrowse link
NAD-dependent histone H3K14 deacetylase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Sirt1 sirtuin 1 enables ISO (PMID:15469825) RGD PMID:15469825 NCBI chr20:25,307,225...25,329,273
Ensembl chr20:25,306,917...25,329,260 		JBrowse link
NAD-dependent histone H3K18 deacetylase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Sirt6 sirtuin 6 enables ISO (PMID:27043296)
(MGI:7258357|PMID:31002797)		 RGD PMID:27043296 PMID:31002797 MGI:7258357 NCBI chr 7:8,082,312...8,087,776
Ensembl chr 7:8,082,364...8,098,914 		JBrowse link
G Sirt7 sirtuin 7 enables ISS
IEA
IBA
ISO		 GO_REF:0000024
GO_REF:0000118
GO_REF:0000033
(MGI:5789069|PMID:27225932), (MGI:6377981|PMID:31226208), (MGI:6378020|PMID:31256246)
(PMID:22722849), (PMID:26907567), (PMID:28655758), (PMID:30420520), (PMID:30653310), (PMID:35939806)		 UniProt
TreeGrafter
GO_Central
RGD		 PMID:22722849 PMID:26907567 PMID:27225932 PMID:28655758 PMID:30420520 More... GO_REF:0000024 GO_REF:0000033 GO_REF:0000118 MGI:5789069 MGI:6377981 MGI:6378020 NCBI chr10:105,896,476...105,903,301
Ensembl chr10:105,896,476...105,903,172 		JBrowse link
NAD-dependent histone H3K56 deacetylase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Sirt6 sirtuin 6 enables ISO (PMID:23911928), (PMID:26456828), (PMID:26898756), (PMID:27912097), (PMID:30374165)
(MGI:4867348|PMID:21098266), (MGI:6103696|PMID:28355567), (MGI:6757299|PMID:25915124), (MGI:7258357|PMID:31002797), (PMID:31399344)		 RGD PMID:21098266 PMID:23911928 PMID:25915124 PMID:26456828 PMID:26898756 More... MGI:4867348 MGI:6103696 MGI:6757299 MGI:7258357 NCBI chr 7:8,082,312...8,087,776
Ensembl chr 7:8,082,364...8,098,914 		JBrowse link
NAD-dependent histone H3K9 deacetylase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Sirt1 sirtuin 1 enables ISO
IEA		 (MGI:4887284|PMID:20972425)
(PMID:15469825)
GO_REF:0000107		 RGD
Ensembl		 PMID:15469825 PMID:20972425 GO_REF:0000107 MGI:4887284 NCBI chr20:25,307,225...25,329,273
Ensembl chr20:25,306,917...25,329,260 		JBrowse link
G Sirt6 sirtuin 6 enables ISO
IBA		 (MGI:4867348|PMID:21098266), (MGI:4881401|PMID:20141841), (MGI:6103696|PMID:28355567), (MGI:6284084|PMID:29555651), (MGI:6357632|PMID:31399344), (MGI:6757299|PMID:25915124), (MGI:7258357|PMID:31002797), (PMID:31399344)
GO_REF:0000033
(PMID:18337721), (PMID:23892288), (PMID:26456828), (PMID:29555651), (PMID:30374165), (PMID:33067423)		 RGD
GO_Central		 PMID:18337721 PMID:20141841 PMID:21098266 PMID:23892288 PMID:25915124 More... GO_REF:0000033 MGI:4867348 MGI:4881401 MGI:6103696 MGI:6284084 MGI:6357632 MGI:6757299 MGI:7258357 NCBI chr 7:8,082,312...8,087,776
Ensembl chr 7:8,082,364...8,098,914 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  molecular_function 21010
    catalytic activity 6153
      catalytic activity, acting on a protein 2516
        protein lysine deacetylase activity 26
          histone deacetylase activity 26
            histone H3K deacetylase activity 4
              NAD-dependent histone H3K18 deacetylase activity 2
              NAD-dependent histone H3K56 deacetylase activity 1
              histone H3K14 deacetylase activity + 2
              histone H3K4 deacetylase activity 0
              histone H3K9 deacetylase activity + 3
Path 2
Term Annotations click to browse term
  molecular_function 21010
    catalytic activity 6153
      hydrolase activity 2639
        hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds 135
          hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides 77
            histone deacetylase activity 26
              histone H3K deacetylase activity 4
                NAD-dependent histone H3K18 deacetylase activity 2
                NAD-dependent histone H3K56 deacetylase activity 1
                histone H3K14 deacetylase activity + 2
                histone H3K4 deacetylase activity 0
                histone H3K9 deacetylase activity + 3
paths to the root