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ONTOLOGY REPORT - ANNOTATIONS

Term:NAD-dependent histone H3K18 deacetylase activity
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Accession:GO:0097372 term browser browse the term
Definition:Catalysis of the reaction: histone H3 N6-acetyl-L-lysine (position 18) + H2O = histone H3 L-lysine (position 18) + acetate. This reaction requires the presence of NAD, and represents the removal of an acetyl group from lysine at position 18 of the histone H3 protein.
Synonyms:exact_synonym: NAD-dependent histone H3-K18 deacetylase activity;   NAD-dependent histone deacetylase activity (H3-K18 specific)


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NAD-dependent histone H3K18 deacetylase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Sirt6 sirtuin 6 enables ISO (PMID:27043296)
(MGI:7258357|PMID:31002797)		 RGD PMID:27043296 PMID:31002797 MGI:7258357 NCBI chr 7:8,082,312...8,087,776
Ensembl chr 7:8,082,364...8,098,914 		JBrowse link
G Sirt7 sirtuin 7 enables ISS
ISO
IBA
IEA		 GO_REF:0000024
(PMID:22722849), (PMID:26907567), (PMID:28655758), (PMID:30420520), (PMID:30653310), (PMID:35939806)
(MGI:5789069|PMID:27225932), (MGI:6377981|PMID:31226208), (MGI:6378020|PMID:31256246)
GO_REF:0000033
GO_REF:0000118		 UniProt
RGD
GO_Central
TreeGrafter		 PMID:22722849 PMID:26907567 PMID:27225932 PMID:28655758 PMID:30420520 More... GO_REF:0000024 GO_REF:0000033 GO_REF:0000118 MGI:5789069 MGI:6377981 MGI:6378020 NCBI chr10:105,896,476...105,903,301
Ensembl chr10:105,896,476...105,903,172 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  molecular_function 20890
    catalytic activity 6118
      catalytic activity, acting on a protein 2496
        protein lysine deacetylase activity 26
          histone deacetylase activity 26
            histone H3K deacetylase activity 4
              NAD-dependent histone H3K18 deacetylase activity 2
Path 2
Term Annotations click to browse term
  molecular_function 20890
    catalytic activity 6118
      hydrolase activity 2630
        hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds 135
          hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides 77
            histone deacetylase activity 26
              NAD-dependent histone deacetylase activity 6
                NAD-dependent histone H3K18 deacetylase activity 2
paths to the root