Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models   new Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources

ONTOLOGY REPORT - ANNOTATIONS

Term:piRNA-mediated retrotransposon silencing by heterochromatin formation
go back to main search page
Accession:GO:0141006 term browser browse the term
Definition:A retrotransposon silencing mechanism in which a Piwi-associated RNA (piRNA) triggers heterochromatin assembly. Heterochromatin is a chromatin conformation that is refractory to transcription.


show annotations for term's descendants           Sort by:
piRNA-mediated retrotransposon silencing by heterochromatin formation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DDX4 DEAD-box helicase 4 acts_upstream_of_positive_effect ISS UniProt GO_REF:0000024 NCBI chr16:34,879,701...34,983,701
Ensembl chr16:34,858,368...34,983,699 		JBrowse link
G PIWIL1 piwi like RNA-mediated gene silencing 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr14:24,729,346...24,760,056
Ensembl chr14:24,729,113...24,760,320 		JBrowse link
G PIWIL2 piwi like RNA-mediated gene silencing 2 involved_in
acts_upstream_of_positive_effect		 IEA
ISO		 (MGI:5501381|PMID:23706823) Ensembl
UniProt		 PMID:23706823 GO_REF:0000107 MGI:5501381 NCBI chr14:6,560,402...6,632,524
Ensembl chr14:6,560,565...6,632,523 		JBrowse link
G SPOCD1 SPOC domain containing 1 involved_in ISO (MGI:6453929|PMID:32674113) UniProt PMID:32674113 MGI:6453929 NCBI chr 6:88,323,119...88,349,194
Ensembl chr 6:88,323,080...88,349,963 		JBrowse link
G TDRD9 tudor domain containing 9 involved_in IEA Ensembl GO_REF:0000107
G TEX15 testis expressed 15, meiosis and synapsis associated involved_in ISO (MGI:6447460|PMID:32719317) UniProt PMID:32719317 MGI:6447460 NCBI chr15:54,210,139...54,277,609 JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 17800
    negative regulation of biological process 5655
      negative regulation of cellular process 5287
        retrotransposon silencing 29
          retrotransposon silencing by heterochromatin formation 19
            piRNA-mediated retrotransposon silencing by heterochromatin formation 6
Path 2
Term Annotations click to browse term
  biological_process 17800
    biological regulation 12906
      regulation of biological process 12539
        regulation of metabolic process 6219
          regulation of biosynthetic process 5091
            regulation of cellular biosynthetic process 5004
              regulation of macromolecule biosynthetic process 4907
                regulation of gene expression 4792
                  negative regulation of gene expression 1355
                    negative regulation of gene expression, epigenetic 170
                      heterochromatin formation 139
                        regulatory ncRNA-mediated heterochromatin formation 21
                          piRNA-mediated heterochromatin formation 7
                            piRNA-mediated retrotransposon silencing by heterochromatin formation 6
paths to the root