Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models   new Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources

ONTOLOGY REPORT - ANNOTATIONS

Term:heterochromatin formation
go back to main search page
Accession:GO:0031507 term browser browse the term
Definition:An epigenetic gene silencing mechanism in which chromatin is compacted into heterochromatin, resulting in a chromatin conformation refractory to transcription. This process starts with heterochromatin nucleation, its spreading, and ends with heterochromatin boundary formation.
Synonyms:exact_synonym: chromatin silencing;   chromatin-mediated silencing;   establishment of heterochromatin architecture;   heterochromatin assembly
 narrow_synonym: establishment of heterochromatin architecture involved in chromatin silencing at centromere outer repeat region;   establishment of heterochromatin architecture involved in chromatin silencing at pericentric region;   heterochromatin assembly involved in chromatin silencing at centromere outer repeat region;   heterochromatin assembly involved in chromatin silencing at pericentric region;   heterochromatin formation involved in chromatin silencing at centromere outer repeat region;   heterochromatin formation involved in chromatin silencing at pericentric region
 broad_synonym: TGS;   heterochromatin maintenance
 related_synonym: establishment of chromatin silencing;   establishment of heterochromatic silencing;   heterochromatic silencing;   heterochromatin assembly involved in chromatin silencing;   heterochromatin formation involved in chromatin silencing;   transcriptional gene silencing
 alt_id: GO:0006342;   GO:0006343;   GO:0016440;   GO:0070869;   GO:1904497


show annotations for term's descendants           Sort by:
heterochromatin formation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bahd1 bromo adjacent homology domain containing 1 involved_in ISO
IBA		 (PMID:19666599)
GO_REF:0000033		 RGD
GO_Central		 PMID:19666599 GO_REF:0000033 NCBI chr 3:105,891,207...105,914,414
Ensembl chr 3:105,892,478...105,914,410 		JBrowse link
G Baz2a bromodomain adjacent to zinc finger domain, 2A acts_upstream_of_or_within ISO (PMID:16678107), (PMID:20168299) RGD PMID:16678107 PMID:20168299 NCBI chr 7:523,204...560,911
Ensembl chr 7:523,265...560,659 		JBrowse link
G Bcl6 BCL6, transcription repressor acts_upstream_of_or_within ISO MGI:2135607 (PMID:23160044) RGD PMID:23160044 NCBI chr11:76,854,090...76,877,389
Ensembl chr11:76,854,090...76,877,389 		JBrowse link
G Cbx1 chromobox 1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr10:81,770,307...81,789,981
Ensembl chr10:81,770,342...81,791,096 		JBrowse link
G Cbx3 chromobox 3 involved_in ISO
IBA		 (PMID:17540172)
GO_REF:0000033		 RGD
GO_Central		 PMID:17540172 GO_REF:0000033 NCBI chr 4:80,545,450...80,559,284
Ensembl chr 4:80,546,010...80,559,283 		JBrowse link
G Cbx3l2 chromobox 3 like 2 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 5:68,280,558...68,281,429
Ensembl chr 5:68,280,970...68,281,345 		JBrowse link
G Cbx5 chromobox 5 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 7:134,333,165...134,376,102
Ensembl chr 7:134,331,335...134,375,022 		JBrowse link
G Dnmt3a DNA methyltransferase 3 alpha acts_upstream_of_or_within ISO (PMID:22516971) RGD PMID:22516971 NCBI chr 6:26,791,517...26,902,161
Ensembl chr 6:26,822,609...26,896,687 		JBrowse link
G Dnmt3b DNA methyltransferase 3 beta acts_upstream_of_or_within ISO (PMID:22516971) RGD PMID:22516971 NCBI chr 3:142,130,588...142,169,128
Ensembl chr 3:142,130,592...142,169,124 		JBrowse link
G Dot1l DOT1 like histone lysine methyltransferase involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 7:8,918,764...8,959,474
Ensembl chr 7:8,917,786...8,956,475 		JBrowse link
G Eed embryonic ectoderm development involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 1:143,867,875...143,895,008
Ensembl chr 1:143,867,875...143,894,974 		JBrowse link
G Efcc1 EF-hand and coiled-coil domain containing 1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 4:120,188,202...120,223,464
Ensembl chr 4:120,188,470...120,217,516 		JBrowse link
G Ezh1 enhancer of zeste 1 polycomb repressive complex 2 subunit involved_in ISO
IBA		 (MGI:3820717|PMID:19026781)
GO_REF:0000033		 RGD
GO_Central		 PMID:19026781 GO_REF:0000033 MGI:3820717 NCBI chr10:86,126,023...86,162,001
Ensembl chr10:86,126,015...86,161,921 		JBrowse link
G Ezh2 enhancer of zeste 2 polycomb repressive complex 2 subunit involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 4:76,624,399...76,687,362
Ensembl chr 4:76,624,399...76,687,362 		JBrowse link
G H1f0 H1.0 linker histone involved_in ISO UniProtKB:P09429 (PMID:19158276) RGD PMID:19158276 NCBI chr 7:110,592,834...110,594,694
Ensembl chr 7:110,592,208...110,594,694 		JBrowse link
G H2ab3 H2A.B variant histone 3 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr  X:82,362,531...82,363,105
Ensembl chr  X:82,362,633...82,362,983 		JBrowse link
G H2ac1 H2A clustered histone 1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr17:41,171,324...41,171,801
Ensembl chr17:41,135,489...41,172,022 		JBrowse link
G H2ac12 H2A clustered histone 12 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr17:42,486,415...42,486,880
Ensembl chr17:42,486,415...42,486,941 		JBrowse link
G H2ac18 H2A clustered histone 18 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 2:183,808,398...183,808,992 JBrowse link
G H2ac21 H2A clustered histone 21 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 2:183,779,355...183,779,788 JBrowse link
G H2ac23 H2A clustered histone 23 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr17:41,532,685...41,533,271
Ensembl chr17:42,478,860...42,479,252
Ensembl chr17:42,478,860...42,479,252 		JBrowse link
G H2ac25 H2A clustered histone 25 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr10:43,733,702...43,735,254
Ensembl chr10:43,733,668...43,744,874 		JBrowse link
G H2ac4 H2A clustered histone 4 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr17:42,799,884...42,800,387
Ensembl chr17:42,799,652...42,800,381 		JBrowse link
G H2aj H2A.J histone involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 4:169,675,718...169,676,202
Ensembl chr 4:169,675,752...169,677,006 		JBrowse link
G H2ax H2A.X variant histone involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 8:44,671,907...44,673,262
Ensembl chr 8:44,671,786...44,673,239 		JBrowse link
G H2az1 H2A.Z variant histone 1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 2:226,355,668...226,357,984
Ensembl chr 2:226,355,708...226,358,485 		JBrowse link
G H2az1-ps2 H2A.Z variant histone 1, pseudogene 2 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 6:6,362,973...6,363,359
Ensembl chr 6:6,362,988...6,363,359 		JBrowse link
G H2az2 H2A.Z variant histone 2 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr14:81,293,304...81,312,209
Ensembl chr14:81,293,299...81,312,144 		JBrowse link
G H2az2l1 H2A.Z histone variant 2 like 1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 4:151,152,904...151,153,567
Ensembl chr 4:151,153,132...151,153,518 		JBrowse link
G H2az2l3 H2A.Z histone variant 2 like 3 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr18:80,609,863...80,610,522
Ensembl chr18:80,609,861...80,610,556 		JBrowse link
G Hdac1 histone deacetylase 1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 5:141,853,992...141,881,057
Ensembl chr 5:141,853,989...141,881,111 		JBrowse link
G Hdac1l histone deacetylase 1-like involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 9:80,452,615...80,454,615
Ensembl chr 9:80,453,139...80,454,593 		JBrowse link
G Hdac2 histone deacetylase 2 involved_in ISO
IBA		 (PMID:19372552)
GO_REF:0000033		 RGD
GO_Central		 PMID:19372552 GO_REF:0000033 NCBI chr20:40,548,244...40,571,609
Ensembl chr20:40,548,250...40,571,609 		JBrowse link
G Hells helicase, lymphoid specific acts_upstream_of_or_within ISO MGI:2178586 (PMID:15448183) RGD PMID:15448183 NCBI chr 1:236,701,704...236,748,239
Ensembl chr 1:236,701,758...236,746,844 		JBrowse link
G Hils1 histone linker H1 domain, spermatid-specific 1 involved_in ISO (PMID:12920187) RGD PMID:12920187 NCBI chr10:79,913,525...79,914,321
Ensembl chr10:79,913,480...79,914,321 		JBrowse link
G Hist1h2ac histone cluster 1 H2A family member C involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr17:42,478,836...42,479,306
Ensembl chr17:42,478,860...42,479,252
Ensembl chr17:42,478,860...42,479,252 		JBrowse link
G Hist1h2af histone cluster 1 H2A family member F involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr17:41,379,404...41,379,796
Ensembl chr17:41,379,404...41,379,796 		JBrowse link
G Hist1h2ah histone cluster 1 H2A family member H involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr17:41,384,521...41,385,018 JBrowse link
G Hist1h2ai histone cluster 1, H2ai involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr17:42,718,310...42,718,797
Ensembl chr17:41,534,691...41,539,869
Ensembl chr17:41,534,691...41,539,869 		JBrowse link
G hist1h2ail2 histone cluster 1, H2ai-like2 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr17:42,753,160...42,753,620
Ensembl chr17:41,534,691...41,539,869
Ensembl chr17:41,534,691...41,539,869 		JBrowse link
G Hist1h2al1 histone cluster 1 H2A family like 1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr17:42,707,954...42,708,420 JBrowse link
G Hist1h2an histone cluster 1, H2an involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr17:41,534,653...41,535,259
Ensembl chr17:41,534,691...41,539,869 		JBrowse link
G Hist1h2anl2 histone cluster 1, H2an like 2 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr17:42,696,845...42,697,423
Ensembl chr17:42,696,791...42,697,295 		JBrowse link
G Hist2h2aa2 histone cluster 2 H2A family member A2 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 2:183,801,308...183,801,891 JBrowse link
G Hmga2 high mobility group AT-hook 2 involved_in ISS
ISO		 GO_REF:0000024
(PMID:16901784)		 UniProt
RGD		 PMID:16901784 GO_REF:0000024 NCBI chr 7:55,877,145...55,998,813
Ensembl chr 7:55,880,112...55,994,784 		JBrowse link
G Hmgb1 high mobility group box 1 involved_in ISO UniProtKB:P07305 (PMID:19158276) RGD PMID:19158276 NCBI chr12:5,972,950...5,979,658
Ensembl chr12:5,901,586...5,978,565
Ensembl chr16:5,901,586...5,978,565 		JBrowse link
G Kmt2d lysine methyltransferase 2D involved_in ISO (MGI:4849597|PMID:20808952) RGD PMID:20808952 MGI:4849597 NCBI chr 7:129,980,744...130,022,088
Ensembl chr 7:129,962,887...130,020,325 		JBrowse link
G L3mbtl1 L3MBTL histone methyl-lysine binding protein 1 involved_in ISO (PMID:17540172) RGD PMID:17540172 NCBI chr 3:151,597,903...151,633,657
Ensembl chr 3:151,602,980...151,631,233 		JBrowse link
G Lmna lamin A/C involved_in IBA
IEA		 GO_REF:0000033
GO_REF:0000118		 GO_Central
TreeGrafter		 GO_REF:0000033 GO_REF:0000118 NCBI chr 2:173,939,751...173,960,423
Ensembl chr 2:173,939,751...173,960,423 		JBrowse link
G Lmnb1 lamin B1 involved_in IBA
IEA		 GO_REF:0000033
GO_REF:0000118		 GO_Central
TreeGrafter		 GO_REF:0000033 GO_REF:0000118 NCBI chr18:50,175,861...50,215,210
Ensembl chr18:50,175,874...50,214,502 		JBrowse link
G Lmnb2 lamin B2 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 7:8,792,628...8,808,665
Ensembl chr 7:8,789,314...8,808,665 		JBrowse link
G Macroh2a1 macroH2A.1 histone involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr17:8,479,331...8,542,071
Ensembl chr17:8,479,372...8,542,072 		JBrowse link
G Macroh2a2 macroH2A.2 histone involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr20:29,678,194...29,727,867
Ensembl chr20:29,678,222...29,727,891 		JBrowse link
G Mecp2 methyl CpG binding protein 2 acts_upstream_of_or_within ISO MGI:2137311 (PMID:15608638) RGD PMID:15608638 NCBI chr  X:151,781,177...151,844,687
Ensembl chr  X:151,789,930...151,844,689 		JBrowse link
G Mis18a MIS18 kinetochore protein A acts_upstream_of_or_within ISO MGI:5441069 (PMID:22516971) RGD PMID:22516971 NCBI chr11:29,968,030...29,981,058
Ensembl chr11:29,967,701...29,981,062 		JBrowse link
G Pole3 DNA polymerase epsilon 3, accessory subunit involved_in IEA
IBA		 GO_REF:0000118
GO_REF:0000033		 TreeGrafter
GO_Central		 GO_REF:0000033 GO_REF:0000118 NCBI chr 5:75,973,941...75,977,175
Ensembl chr 5:75,974,717...75,977,231
Ensembl chr 7:75,974,717...75,977,231 		JBrowse link
G Pole3-ps2 DNA polymerase epsilon 3, accessory subunit, pseudogene 2 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr17:26,135,927...26,136,417
Ensembl chr17:26,135,927...26,136,235
Ensembl chr17:26,135,927...26,136,235 		JBrowse link
G Rb1 RB transcriptional corepressor 1 involved_in ISO
IEA		 (PMID:17540172)
GO_REF:0000107		 RGD
Ensembl		 PMID:17540172 GO_REF:0000107 NCBI chr15:48,371,295...48,502,473
Ensembl chr15:48,371,296...48,502,302 		JBrowse link
G Sin3a SIN3 transcription regulator family member A involved_in ISO (PMID:22783022) RGD PMID:22783022 NCBI chr 8:57,481,539...57,536,195
Ensembl chr 8:57,481,573...57,536,192 		JBrowse link
G Sirt1 sirtuin 1 involved_in
acts_upstream_of_or_within		 ISO
IEA		 (PMID:15469825)
MGI:107187 (PMID:23160044)
GO_REF:0000107		 RGD
Ensembl		 PMID:15469825 PMID:23160044 GO_REF:0000107 NCBI chr20:25,307,225...25,329,273
Ensembl chr20:25,306,917...25,329,260 		JBrowse link
G Smarca5 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5 involved_in ISO (MGI:3653583|PMID:16678107) RGD PMID:16678107 MGI:3653583 NCBI chr19:27,271,918...27,304,594
Ensembl chr19:27,271,148...27,304,594 		JBrowse link
G Spty2d1 SPT2 chromatin protein domain containing 1 involved_in ISO (PMID:26109053) RGD PMID:26109053 NCBI chr 1:97,531,495...97,549,616
Ensembl chr 1:97,531,508...97,549,581 		JBrowse link
G Tnp1 transition protein 1 involved_in ISO
ISS		 (PMID:11315969)
GO_REF:0000024		 RGD
UniProt		 PMID:11315969 GO_REF:0000024 NCBI chr 9:74,594,463...74,595,072
Ensembl chr 9:74,594,466...74,595,274 		JBrowse link
G Ubr2 ubiquitin protein ligase E3 component n-recognin 2 involved_in ISO (MGI:4431162|PMID:20080676) RGD PMID:20080676 MGI:4431162 NCBI chr 9:13,982,427...14,062,315
Ensembl chr 9:13,982,329...14,062,139 		JBrowse link
G Uhrf1 ubiquitin-like with PHD and ring finger domains 1 involved_in ISO
IEA
ISS		 (PMID:17967883)
GO_REF:0000107
GO_REF:0000024		 RGD
Ensembl
UniProt		 PMID:17967883 GO_REF:0000024 GO_REF:0000107 NCBI chr 9:1,133,117...1,154,639
Ensembl chr 9:1,134,909...1,154,631 		JBrowse link
G Uty ubiquitously transcribed tetratricopeptide repeat containing, Y-linked acts_upstream_of_or_within ISO (PMID:22192413) RGD PMID:22192413 NCBI chr  Y:942,838...1,105,313
Ensembl chr  Y:924,168...1,103,422 		JBrowse link
DNA methylation-dependent heterochromatin formation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bend3 BEN domain containing 3 involved_in ISO (PMID:26100909) RGD PMID:26100909 NCBI chr20:46,980,246...47,017,059
Ensembl chr20:46,979,831...47,014,671 		JBrowse link
G Bmi1 BMI1 proto-oncogene, polycomb ring finger acts_upstream_of_or_within ISO (PMID:24105743) RGD PMID:24105743 NCBI chr17:81,332,175...81,341,625
Ensembl chr17:81,332,214...81,388,690 		JBrowse link
G Ctcf CCCTC-binding factor acts_upstream_of_or_within ISO (PMID:24105743) RGD PMID:24105743 NCBI chr19:33,521,726...33,571,124
Ensembl chr19:33,529,319...33,571,123 		JBrowse link
G Dnmt1 DNA methyltransferase 1 involved_in ISO
IEA		 (MGI:3687778|PMID:10615135)
GO_REF:0000107		 RGD
Ensembl		 PMID:10615135 GO_REF:0000107 MGI:3687778 NCBI chr 8:19,440,611...19,486,659
Ensembl chr 8:19,440,611...19,486,659 		JBrowse link
G Dnmt3a DNA methyltransferase 3 alpha involved_in
acts_upstream_of_or_within		 ISO (PMID:30478443)
MGI:1261819 (PMID:16322236), (PMID:17938196)		 RGD PMID:16322236 PMID:17938196 PMID:30478443 NCBI chr 6:26,791,517...26,902,161
Ensembl chr 6:26,822,609...26,896,687 		JBrowse link
G Dnmt3b DNA methyltransferase 3 beta acts_upstream_of_or_within ISO MGI:1261827 (PMID:17938196) RGD PMID:17938196 NCBI chr 3:142,130,588...142,169,128
Ensembl chr 3:142,130,592...142,169,124 		JBrowse link
G Dnmt3l DNA methyltransferase 3 like involved_in IEA
ISO
ISS		 GO_REF:0000107
(MGI:5553039|PMID:24074865)
GO_REF:0000024		 Ensembl
RGD
UniProt		 PMID:24074865 GO_REF:0000024 GO_REF:0000107 MGI:5553039 NCBI chr20:10,614,933...10,629,337
Ensembl chr20:10,614,934...10,629,516 		JBrowse link
G Ehmt1 euchromatic histone lysine methyltransferase 1 involved_in ISO (MGI:3826717|PMID:18818694) RGD PMID:18818694 MGI:3826717 NCBI chr 3:7,580,680...7,729,046
Ensembl chr 3:7,580,683...7,729,007 		JBrowse link
G Ehmt2 euchromatic histone lysine methyltransferase 2 involved_in ISO (MGI:3826717|PMID:18818694) RGD PMID:18818694 MGI:3826717 NCBI chr20:3,919,623...3,936,751
Ensembl chr20:3,919,624...3,941,547 		JBrowse link
G Ezh2 enhancer of zeste 2 polycomb repressive complex 2 subunit acts_upstream_of_or_within ISO (PMID:24105743) RGD PMID:24105743 NCBI chr 4:76,624,399...76,687,362
Ensembl chr 4:76,624,399...76,687,362 		JBrowse link
G Hdac1 histone deacetylase 1 involved_in ISO UniProtKB:Q9UBB5 (PMID:23770133) RGD PMID:23770133 NCBI chr 5:141,853,992...141,881,057
Ensembl chr 5:141,853,989...141,881,111 		JBrowse link
G Hells helicase, lymphoid specific involved_in ISO
IBA		 (MGI:3573964|PMID:15647320)
GO_REF:0000033		 RGD
GO_Central		 PMID:15647320 GO_REF:0000033 MGI:3573964 NCBI chr 1:236,701,704...236,748,239
Ensembl chr 1:236,701,758...236,746,844 		JBrowse link
G Kmt2b lysine methyltransferase 2B acts_upstream_of_or_within ISO MGI:3056522|MGI:3623309 (PMID:20808952) RGD PMID:20808952 NCBI chr 1:85,821,700...85,840,987
Ensembl chr 1:85,821,753...85,841,326 		JBrowse link
G Mbd1 methyl-CpG binding domain protein 1 involved_in IEA GO_REF:0000118 TreeGrafter GO_REF:0000118 NCBI chr18:67,869,870...67,884,501
Ensembl chr18:67,869,992...67,886,554 		JBrowse link
G Mbd2 methyl-CpG binding domain protein 2 involved_in ISO
IBA		 UniProtKB:Q13547 (PMID:23770133)
GO_REF:0000033		 RGD
GO_Central		 PMID:23770133 GO_REF:0000033 NCBI chr18:64,174,002...64,240,795
Ensembl chr18:64,174,002...64,240,794 		JBrowse link
G Mbd3 methyl-CpG binding domain protein 3 involved_in
acts_upstream_of_or_within		 IBA
ISO		 GO_REF:0000033
(PMID:16322236)		 GO_Central
RGD		 PMID:16322236 GO_REF:0000033 NCBI chr 7:9,312,961...9,320,166
Ensembl chr 7:9,313,098...9,320,165 		JBrowse link
G Mbd3l1 methyl-CpG binding domain protein 3-like 1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 8:16,150,539...16,160,463
Ensembl chr 8:16,153,472...16,160,404 		JBrowse link
G Mbd3l2 methyl-CpG binding domain protein 3-like 2 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 8:15,607,477...15,614,046
Ensembl chr 8:15,611,214...15,612,563 		JBrowse link
G Ppm1d protein phosphatase, Mg2+/Mn2+ dependent, 1D involved_in ISO (MGI:5551345|PMID:24135283) RGD PMID:24135283 MGI:5551345 NCBI chr10:70,172,603...70,208,607
Ensembl chr10:70,172,603...70,208,607 		JBrowse link
G Smarca4 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 acts_upstream_of_or_within ISO (PMID:16322236) RGD PMID:16322236 NCBI chr 8:20,167,717...20,258,975
Ensembl chr 8:20,167,717...20,258,975 		JBrowse link
G Tex15 testis expressed 15, meiosis and synapsis associated acts_upstream_of_or_within_positive_effect ISO (MGI:6434559|PMID:32381626) RGD PMID:32381626 MGI:6434559 NCBI chr16:58,598,991...58,659,005
Ensembl chr16:58,598,989...58,658,467 		JBrowse link
dosage compensation by inactivation of X chromosome term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Brca1 BRCA1, DNA repair associated involved_in IEA GO_REF:0000118 TreeGrafter GO_REF:0000118 NCBI chr10:86,417,441...86,477,762
Ensembl chr10:86,418,000...86,477,304 		JBrowse link
G Hnrnpu heterogeneous nuclear ribonucleoprotein U involved_in ISO (MGI:4831049|PMID:20833368) RGD PMID:20833368 MGI:4831049 NCBI chr13:90,069,058...90,086,905
Ensembl chr13:90,074,181...90,086,588 		JBrowse link
G Lrif1 ligand dependent nuclear receptor interacting factor 1 involved_in ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
(PMID:23542155)		 UniProt
Ensembl
RGD		 PMID:23542155 GO_REF:0000024 GO_REF:0000107 NCBI chr 2:194,231,397...194,322,489
Ensembl chr 2:194,230,951...194,322,483 		JBrowse link
G Mettl3 methyltransferase 3, N6-adenosine-methyltransferase complex catalytic subunit involved_in ISO (PMID:27602518) RGD PMID:27602518 NCBI chr15:25,002,505...25,014,097
Ensembl chr15:25,003,172...25,014,041 		JBrowse link
G Rbm15 RNA binding motif protein 15 involved_in ISO (PMID:27602518) RGD PMID:27602518 NCBI chr 2:194,945,974...194,954,498
Ensembl chr 2:194,945,974...194,954,703 		JBrowse link
G Rbm15b RNA binding motif protein 15B involved_in ISO (PMID:27602518) RGD PMID:27602518 NCBI chr 8:107,543,613...107,546,678
Ensembl chr 8:107,525,898...107,551,696 		JBrowse link
G Smchd1 structural maintenance of chromosomes flexible hinge domain containing 1 involved_in ISO (PMID:23542155) RGD PMID:23542155 NCBI chr 9:111,243,445...111,387,272
Ensembl chr 9:111,247,702...111,349,665 		JBrowse link
G Ythdc1 YTH N6-methyladenosine RNA binding protein C1 involved_in ISO
ISS		 (PMID:27602518)
GO_REF:0000024		 RGD
UniProt		 PMID:27602518 GO_REF:0000024 NCBI chr14:21,185,438...21,215,934
Ensembl chr14:21,185,440...21,216,028 		JBrowse link
facultative heterochromatin formation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Eed embryonic ectoderm development involved_in ISO (MGI:4431292|PMID:20064375), (MGI:4436818|PMID:20064376) RGD PMID:20064375 PMID:20064376 MGI:4431292 MGI:4436818 NCBI chr 1:143,867,875...143,895,008
Ensembl chr 1:143,867,875...143,894,974 		JBrowse link
G Ehmt1 euchromatic histone lysine methyltransferase 1 involved_in ISO (MGI:4441247|PMID:19010785) RGD PMID:19010785 MGI:4441247 NCBI chr 3:7,580,680...7,729,046
Ensembl chr 3:7,580,683...7,729,007 		JBrowse link
G Ezh1 enhancer of zeste 1 polycomb repressive complex 2 subunit involved_in ISO (MGI:4436818|PMID:20064376) RGD PMID:20064376 MGI:4436818 NCBI chr10:86,126,023...86,162,001
Ensembl chr10:86,126,015...86,161,921 		JBrowse link
G Ezh2 enhancer of zeste 2 polycomb repressive complex 2 subunit involved_in ISO (MGI:4431292|PMID:20064375), (MGI:4436818|PMID:20064376) RGD PMID:20064375 PMID:20064376 MGI:4431292 MGI:4436818 NCBI chr 4:76,624,399...76,687,362
Ensembl chr 4:76,624,399...76,687,362 		JBrowse link
G Jarid2 jumonji and AT-rich interaction domain containing 2 involved_in ISO (MGI:4431292|PMID:20064375), (MGI:4436818|PMID:20064376), (MGI:4441247|PMID:19010785) RGD PMID:19010785 PMID:20064375 PMID:20064376 MGI:4431292 MGI:4436818 MGI:4441247 NCBI chr17:19,777,487...19,957,696
Ensembl chr17:19,777,266...19,955,690 		JBrowse link
G Kdm5a lysine demethylase 5A involved_in ISO (MGI:4431292|PMID:20064375) RGD PMID:20064375 MGI:4431292 NCBI chr 4:153,565,909...153,643,912
Ensembl chr 4:153,565,846...153,642,422 		JBrowse link
G Suz12 SUZ12 polycomb repressive complex 2 subunit involved_in ISO (MGI:4431292|PMID:20064375), (MGI:4436818|PMID:20064376) RGD PMID:20064375 PMID:20064376 MGI:4431292 MGI:4436818 NCBI chr10:64,967,035...65,012,916
Ensembl chr10:64,966,967...65,012,738 		JBrowse link
gene silencing by piRNA-directed DNA methylation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dnmt3b DNA methyltransferase 3 beta acts_upstream_of_or_within ISO (PMID:27856912) RGD PMID:27856912 NCBI chr 3:142,130,588...142,169,128
Ensembl chr 3:142,130,592...142,169,124 		JBrowse link
heterochromatin boundary formation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Trip12 thyroid hormone receptor interactor 12 involved_in ISO
ISS		 (PMID:22884692)
GO_REF:0000024		 RGD
UniProt		 PMID:22884692 GO_REF:0000024 NCBI chr 9:85,916,691...86,043,312
Ensembl chr 9:85,916,691...86,051,403 		JBrowse link
G Ubr5 ubiquitin protein ligase E3 component n-recognin 5 involved_in ISO
IEA
ISS		 (PMID:22884692)
GO_REF:0000107
GO_REF:0000024		 RGD
Ensembl
UniProt		 PMID:22884692 GO_REF:0000024 GO_REF:0000107 NCBI chr 7:69,115,216...69,224,843
Ensembl chr 7:69,116,761...69,224,903 		JBrowse link
inactivation of paternal X chromosome by genomic imprinting term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Prdm14 PR/SET domain 14 acts_upstream_of_or_within ISO MGI:3805889 (PMID:24268575) RGD PMID:24268575 NCBI chr 5:6,082,163...6,092,712
Ensembl chr 5:6,082,442...6,092,712 		JBrowse link
G Smchd1 structural maintenance of chromosomes flexible hinge domain containing 1 acts_upstream_of_or_within ISO MGI:3586547 (PMID:18425126), (PMID:23754746) RGD PMID:18425126 PMID:23754746 NCBI chr 9:111,243,445...111,387,272
Ensembl chr 9:111,247,702...111,349,665 		JBrowse link
G Xist X inactive specific transcript acts_upstream_of_or_within ISO MGI:1336196|MGI:2445460 (PMID:15992549), (PMID:22573614), (PMID:23658530) RGD PMID:15992549 PMID:22573614 PMID:23658530 NCBI chr  X:68,474,987...68,492,500 JBrowse link
negative regulation of DNA methylation-dependent heterochromatin formation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dnmt3l DNA methyltransferase 3 like involved_in IEA
ISS
ISO		 GO_REF:0000107
GO_REF:0000024
(MGI:5553039|PMID:24074865)		 Ensembl
UniProt
RGD		 PMID:24074865 GO_REF:0000024 GO_REF:0000107 MGI:5553039 NCBI chr20:10,614,933...10,629,337
Ensembl chr20:10,614,934...10,629,516 		JBrowse link
G Dyrk1a dual specificity tyrosine phosphorylation regulated kinase 1A involved_in ISO
IEA		 (PMID:24820035)
GO_REF:0000107		 RGD
Ensembl		 PMID:24820035 GO_REF:0000107 NCBI chr11:33,890,706...34,009,420
Ensembl chr11:33,890,490...34,009,420 		JBrowse link
G Kmt2a lysine methyltransferase 2A involved_in ISO (PMID:20010842) RGD PMID:20010842 NCBI chr 8:45,116,763...45,193,320
Ensembl chr 8:45,118,814...45,193,181 		JBrowse link
negative regulation of heterochromatin formation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Rlf RLF zinc finger acts_upstream_of_or_within ISO MGI:5515366 (PMID:25857663) RGD PMID:25857663 NCBI chr 5:134,711,612...134,767,274
Ensembl chr 5:134,711,619...134,767,257 		JBrowse link
negative regulation of rDNA heterochromatin formation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Phf2 PHD finger protein 2 involved_in ISO (PMID:20129925) RGD PMID:20129925 NCBI chr17:15,783,221...15,851,209
Ensembl chr17:15,781,864...15,851,208 		JBrowse link
G Phf8 PHD finger protein 8 involved_in ISO (PMID:20208542) RGD PMID:20208542 NCBI chr  X:20,524,103...20,623,459
Ensembl chr  X:20,524,558...20,623,410 		JBrowse link
pericentric heterochromatin formation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cenpv centromere protein V involved_in ISO
IBA		 (PMID:18772885)
GO_REF:0000033		 RGD
GO_Central		 PMID:18772885 GO_REF:0000033 NCBI chr10:47,214,479...47,228,552
Ensembl chr10:47,214,490...47,228,761 		JBrowse link
G Dicer1 dicer 1 ribonuclease III acts_upstream_of_or_within ISO MGI:3589287 (PMID:15713842) RGD PMID:15713842 NCBI chr 6:123,627,529...123,692,278
Ensembl chr 6:123,631,250...123,693,965 		JBrowse link
G H3f3a H3.3 histone A acts_upstream_of_or_within ISO MGI:1101768 (PMID:26159997) RGD PMID:26159997 NCBI chr13:92,533,289...92,544,902
Ensembl chr13:92,533,298...92,544,908 		JBrowse link
G H3f3b H3.3 histone B acts_upstream_of_or_within ISO MGI:1097686 (PMID:26159997) RGD PMID:26159997 NCBI chr10:101,256,484...101,258,716
Ensembl chr10:101,256,480...101,258,709 		JBrowse link
G Hells helicase, lymphoid specific involved_in ISO
IBA		 (MGI:3041983|PMID:14612388)
GO_REF:0000033		 RGD
GO_Central		 PMID:14612388 GO_REF:0000033 MGI:3041983 NCBI chr 1:236,701,704...236,748,239
Ensembl chr 1:236,701,758...236,746,844 		JBrowse link
G Sirt6 sirtuin 6 involved_in ISO (PMID:27043296) RGD PMID:27043296 NCBI chr 7:8,082,312...8,087,776
Ensembl chr 7:8,082,364...8,098,914 		JBrowse link
pericentric heterochromatin organization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mis18a MIS18 kinetochore protein A acts_upstream_of_or_within ISO MGI:5441069 (PMID:22516971) RGD PMID:22516971 NCBI chr11:29,968,030...29,981,058
Ensembl chr11:29,967,701...29,981,062 		JBrowse link
G Wdhd1 WD repeat and HMG-box DNA binding protein 1 acts_upstream_of_or_within ISO (PMID:21266480) RGD PMID:21266480 NCBI chr15:20,478,310...20,523,106
Ensembl chr15:20,489,291...20,523,096 		JBrowse link
piRNA-mediated retrotransposon silencing by heterochromatin formation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ddx4 DEAD-box helicase 4 acts_upstream_of_positive_effect ISS
ISO		 GO_REF:0000024
(MGI:5908740|PMID:28633017)		 UniProt
RGD		 PMID:28633017 GO_REF:0000024 MGI:5908740 NCBI chr 2:44,227,946...44,282,867
Ensembl chr 2:44,227,946...44,282,723 		JBrowse link
G Dnmt3c DNA methyltransferase 3C involved_in IEA GO_REF:0000107 Ensembl GO_REF:0000107 Ensembl chr 3:142,178,533...142,210,954 JBrowse link
G Piwil1 piwi-like RNA-mediated gene silencing 1 involved_in ISO (MGI:5316869|PMID:22121019) RGD PMID:22121019 MGI:5316869 NCBI chr12:27,949,743...27,970,645
Ensembl chr12:27,949,744...27,970,580 		JBrowse link
G Piwil2 piwi-like RNA-mediated gene silencing 2 acts_upstream_of_positive_effect ISO (MGI:5501381|PMID:23706823) RGD PMID:23706823 MGI:5501381 NCBI chr15:45,431,402...45,498,034
Ensembl chr15:45,431,703...45,497,702 		JBrowse link
G Spocd1 SPOC domain containing 1 involved_in ISO (MGI:6453929|PMID:32674113) RGD PMID:32674113 MGI:6453929 NCBI chr 5:142,288,822...142,297,113 JBrowse link
G Tdrd9 tudor domain containing 9 involved_in ISS
ISO		 GO_REF:0000024
(MGI:5908740|PMID:28633017)		 UniProt
RGD		 PMID:28633017 GO_REF:0000024 MGI:5908740 NCBI chr 6:131,029,644...131,145,076
Ensembl chr 6:131,029,652...131,144,651 		JBrowse link
G Tex15 testis expressed 15, meiosis and synapsis associated involved_in ISO (MGI:6447460|PMID:32719317) RGD PMID:32719317 MGI:6447460 NCBI chr16:58,598,991...58,659,005
Ensembl chr16:58,598,989...58,658,467 		JBrowse link
positive regulation of DNA methylation-dependent heterochromatin formation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atf7ip activating transcription factor 7 interacting protein involved_in ISO
IBA		 (PMID:27732843)
GO_REF:0000033		 RGD
GO_Central		 PMID:27732843 GO_REF:0000033 NCBI chr 4:169,385,872...169,471,652
Ensembl chr 4:169,385,872...169,471,650 		JBrowse link
G Atf7ip2 activating transcription factor 7 interacting protein 2 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr10:5,403,099...5,445,989
Ensembl chr10:5,403,105...5,446,142 		JBrowse link
G LOC120093070 PHD finger protein 11-like involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr15:33,526,380...33,549,382
Ensembl chr15:33,453,952...33,606,470 		JBrowse link
G LOC120093163 PHD finger protein 11-like involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr15:33,453,948...33,475,669
Ensembl chr15:33,453,952...33,606,470 		JBrowse link
G Morc2 MORC family CW-type zinc finger 2 involved_in ISO (PMID:28581500), (PMID:29211708)
(MGI:6271895|PMID:29728365)		 RGD PMID:28581500 PMID:29211708 PMID:29728365 MGI:6271895 NCBI chr14:78,529,603...78,571,375
Ensembl chr14:78,527,009...78,571,343 		JBrowse link
G Mphosph8 M-phase phosphoprotein 8 involved_in ISS
ISO		 GO_REF:0000024
(PMID:28581500), (PMID:29211708)		 UniProt
RGD		 PMID:28581500 PMID:29211708 GO_REF:0000024 NCBI chr15:30,800,546...30,828,415
Ensembl chr15:30,686,613...30,828,810 		JBrowse link
G Pphln1 periphilin 1 involved_in ISO (PMID:28581500) RGD PMID:28581500 NCBI chr 7:124,538,594...124,629,985
Ensembl chr 7:124,538,627...124,629,985 		JBrowse link
G Resf1 retroelement silencing factor 1 involved_in ISO
IBA		 (MGI:6271895|PMID:29728365)
GO_REF:0000033		 RGD
GO_Central		 PMID:29728365 GO_REF:0000033 MGI:6271895 NCBI chr 4:182,325,913...182,362,054
Ensembl chr 4:182,335,454...182,362,054 		JBrowse link
G Setdb1 SET domain bifurcated histone lysine methyltransferase 1 involved_in ISO
IBA		 (PMID:24623306), (PMID:27732843)
GO_REF:0000033
(MGI:5440670|PMID:20164836), (MGI:6271895|PMID:29728365)		 RGD
GO_Central		 PMID:20164836 PMID:24623306 PMID:27732843 PMID:29728365 GO_REF:0000033 MGI:5440670 MGI:6271895 NCBI chr 2:182,898,738...182,930,283
Ensembl chr 2:182,898,738...182,930,506 		JBrowse link
G Setdb2 SET domain bifurcated histone lysine methyltransferase 2 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr15:33,553,657...33,606,586
Ensembl chr15:33,453,952...33,606,470 		JBrowse link
G Tasor transcription activation suppressor involved_in ISO
IBA		 (PMID:28581500), (PMID:29211708)
GO_REF:0000033		 RGD
GO_Central		 PMID:28581500 PMID:29211708 GO_REF:0000033 NCBI chr16:2,606,807...2,669,902
Ensembl chr16:2,603,936...2,667,292 		JBrowse link
G Trim28 tripartite motif-containing 28 involved_in ISS
ISO		 GO_REF:0000024
(MGI:5440670|PMID:20164836)
(PMID:24623306)		 UniProt
RGD		 PMID:20164836 PMID:24623306 GO_REF:0000024 MGI:5440670 NCBI chr 1:73,652,441...73,659,388
Ensembl chr 1:73,652,709...73,659,380 		JBrowse link
positive regulation of heterochromatin formation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cdk2 cyclin dependent kinase 2 involved_in ISO
IEA		 (PMID:20935635)
GO_REF:0000107		 RGD
Ensembl		 PMID:20935635 GO_REF:0000107 NCBI chr 7:1,129,878...1,137,431
Ensembl chr 7:1,129,811...1,137,403 		JBrowse link
G Tpr translocated promoter region, nuclear basket protein involved_in ISO
IEA
ISS		 (PMID:20407419)
GO_REF:0000107
GO_REF:0000024		 RGD
Ensembl
UniProt		 PMID:20407419 GO_REF:0000024 GO_REF:0000107 NCBI chr13:62,424,312...62,487,502
Ensembl chr13:62,424,312...62,487,496 		JBrowse link
random inactivation of X chromosome term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Brca1 BRCA1, DNA repair associated involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:98974 (PMID:12419249)		 Ensembl
RGD		 PMID:12419249 GO_REF:0000107 NCBI chr10:86,417,441...86,477,762
Ensembl chr10:86,418,000...86,477,304 		JBrowse link
G Cdyl chromodomain Y-like involved_in ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
(MGI:5551942|PMID:24144980)		 UniProt
Ensembl
RGD		 PMID:24144980 GO_REF:0000024 GO_REF:0000107 MGI:5551942 NCBI chr17:28,982,009...29,204,345
Ensembl chr17:28,982,037...29,204,313 		JBrowse link
G Ftx FTX transcript, XIST regulator acts_upstream_of_or_within ISO MGI:1342291|MGI:2180008 (PMID:21118898), (PMID:24613346) RGD PMID:21118898 PMID:24613346 NCBI chr  X:68,588,349...68,630,338 JBrowse link
G Jarid2 jumonji and AT-rich interaction domain containing 2 acts_upstream_of_or_within ISO MGI:5888989 (PMID:27892467) RGD PMID:27892467 NCBI chr17:19,777,487...19,957,696
Ensembl chr17:19,777,266...19,955,690 		JBrowse link
G Jpx JPX transcript, XIST activator acts_upstream_of
acts_upstream_of_or_within		 ISO MGI:4887255 (PMID:21029862)
MGI:1342291|MGI:1926128 (PMID:21029862), (PMID:24613346)		 RGD PMID:21029862 PMID:24613346 NCBI chr  X:68,511,491...68,665,132 JBrowse link
G Pcgf3 polycomb group ring finger 3 involved_in ISO (MGI:5908473|PMID:28596365) RGD PMID:28596365 MGI:5908473 NCBI chr14:1,237,594...1,291,717
Ensembl chr14:1,233,947...1,291,793 		JBrowse link
G Pcgf5 polycomb group ring finger 5 involved_in ISO (MGI:5908473|PMID:28596365) RGD PMID:28596365 MGI:5908473 NCBI chr 1:234,063,854...234,180,022
Ensembl chr 1:234,063,892...234,175,315 		JBrowse link
G Rlim ring finger protein, LIM domain interacting involved_in
acts_upstream_of_or_within		 ISO
IBA		 (PMID:19945382)
MGI:1926128|MGI:2180008 (PMID:24613346)
GO_REF:0000033
(MGI:4418586|PMID:19945382)		 RGD
GO_Central		 PMID:19945382 PMID:24613346 GO_REF:0000033 MGI:4418586 NCBI chr  X:68,983,259...69,004,368
Ensembl chr  X:68,988,375...69,004,271 		JBrowse link
G Srsf8 serine and arginine rich splicing factor 8 involved_in IEA GO_REF:0000118 TreeGrafter GO_REF:0000118 NCBI chr  X:45,695,314...45,741,153
Ensembl chr  X:45,695,313...45,741,134 		JBrowse link
G Suz12 SUZ12 polycomb repressive complex 2 subunit acts_upstream_of_or_within ISO (PMID:27892467) RGD PMID:27892467 NCBI chr10:64,967,035...65,012,916
Ensembl chr10:64,966,967...65,012,738 		JBrowse link
G Xist X inactive specific transcript involved_in
acts_upstream_of_or_within		 ISO (PMID:9335338)
MGI:104537 (PMID:12419249), (PMID:27892467)		 RGD PMID:9335338 PMID:12419249 PMID:27892467 NCBI chr  X:68,474,987...68,492,500 JBrowse link
rDNA heterochromatin formation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Baz2a bromodomain adjacent to zinc finger domain, 2A involved_in
acts_upstream_of_or_within		 ISO (MGI:3587127|PMID:16085498), (MGI:3852313|PMID:12198165), (MGI:3852588|PMID:19578370)
(PMID:16678107), (PMID:20168299)		 RGD PMID:12198165 PMID:16085498 PMID:16678107 PMID:19578370 PMID:20168299 MGI:3587127 MGI:3852313 MGI:3852588 NCBI chr 7:523,204...560,911
Ensembl chr 7:523,265...560,659 		JBrowse link
G Bend3 BEN domain containing 3 involved_in ISO
IBA		 (PMID:26100909)
GO_REF:0000033		 RGD
GO_Central		 PMID:26100909 GO_REF:0000033 NCBI chr20:46,980,246...47,017,059
Ensembl chr20:46,979,831...47,014,671 		JBrowse link
G Rrp8 ribosomal RNA processing 8 involved_in ISS
IBA
IEA
ISO		 GO_REF:0000024
GO_REF:0000033
GO_REF:0000118
GO_REF:0000107
(PMID:18485871)		 UniProt
GO_Central
TreeGrafter
Ensembl
RGD		 PMID:18485871 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 GO_REF:0000118 NCBI chr 1:160,081,092...160,088,709
Ensembl chr 1:160,084,295...160,089,331 		JBrowse link
G Sirt1 sirtuin 1 involved_in ISO (PMID:18485871) RGD PMID:18485871 NCBI chr20:25,307,225...25,329,273
Ensembl chr20:25,306,917...25,329,260 		JBrowse link
G Smarca5 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5 involved_in ISO (MGI:3587127|PMID:16085498), (MGI:3852313|PMID:12198165) RGD PMID:12198165 PMID:16085498 MGI:3587127 MGI:3852313 NCBI chr19:27,271,918...27,304,594
Ensembl chr19:27,271,148...27,304,594 		JBrowse link
G Suv39h1 SUV39H1 histone lysine methyltransferase involved_in ISO (PMID:18485871) RGD PMID:18485871 NCBI chr  X:14,421,028...14,433,993
Ensembl chr  X:14,421,109...14,433,982 		JBrowse link
G Suv39h1-ps1 SUV39H1 histone lysine methyltransferase, pseudogene 1 involved_in ISO (PMID:18485871) RGD PMID:18485871 NCBI chr  X:141,792,589...141,795,257 JBrowse link
regulation of DNA methylation-dependent heterochromatin formation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Kdm1a lysine demethylase 1A involved_in ISO (PMID:33980486) RGD PMID:33980486 NCBI chr 5:148,782,976...148,838,319
Ensembl chr 5:148,782,976...148,838,319 		JBrowse link
G L3mbtl3 L3MBTL histone methyl-lysine binding protein 3 involved_in ISO (PMID:33980486) RGD PMID:33980486 NCBI chr 1:18,988,763...19,089,247
Ensembl chr 1:18,990,618...19,089,263 		JBrowse link
G Samd1 sterile alpha motif domain containing 1 involved_in ISO (PMID:33980486) RGD PMID:33980486 NCBI chr19:24,151,136...24,154,475
Ensembl chr19:24,151,128...24,154,488 		JBrowse link
regulation of heterochromatin formation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Baz1a bromodomain adjacent to zinc finger domain, 1A involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 6:72,389,701...72,512,516
Ensembl chr 6:72,389,703...72,512,459 		JBrowse link
regulation of rDNA heterochromatin formation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Macroh2a1 macroH2A.1 histone NOT|involved_in ISO (PMID:24071584) RGD PMID:24071584 NCBI chr17:8,479,331...8,542,071
Ensembl chr17:8,479,372...8,542,072 		JBrowse link
regulatory ncRNA-mediated heterochromatin formation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Arb2a ARB2 cotranscriptional regulator A involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 2:7,553,873...8,018,183
Ensembl chr 2:7,553,891...8,018,162 		JBrowse link
G Dnmt3a DNA methyltransferase 3 alpha involved_in ISO RNAcentral:URS00008121D0_9606 (PMID:23435381) RGD PMID:23435381 NCBI chr 6:26,791,517...26,902,161
Ensembl chr 6:26,822,609...26,896,687 		JBrowse link
G Ezh2 enhancer of zeste 2 polycomb repressive complex 2 subunit involved_in ISO RNAcentral:URS00008121D0_9606 (PMID:23435381) RGD PMID:23435381 NCBI chr 4:76,624,399...76,687,362
Ensembl chr 4:76,624,399...76,687,362 		JBrowse link
G Nrde2 NRDE-2, necessary for RNA interference, domain containing involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 6:119,405,103...119,446,861
Ensembl chr 6:119,404,334...119,448,915 		JBrowse link
G Znfx1 zinc finger, NFX1-type containing 1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 3:155,764,073...155,791,777
Ensembl chr 3:155,764,980...155,821,242 		JBrowse link
subtelomeric heterochromatin formation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atrx ATRX, chromatin remodeler involved_in ISS
ISO
IEA		 GO_REF:0000024
(PMID:26055325)
GO_REF:0000107
(MGI:4881400|PMID:20211137)		 UniProt
RGD
Ensembl		 PMID:20211137 PMID:26055325 GO_REF:0000024 GO_REF:0000107 MGI:4881400 NCBI chr  X:70,850,981...70,997,330
Ensembl chr  X:70,850,981...70,997,330 		JBrowse link
G Ezh1 enhancer of zeste 1 polycomb repressive complex 2 subunit involved_in ISO UniProtKB:P38827 (MGI:892875|PMID:9214638) RGD PMID:9214638 MGI:892875 NCBI chr10:86,126,023...86,162,001
Ensembl chr10:86,126,015...86,161,921 		JBrowse link
G Ezh2 enhancer of zeste 2 polycomb repressive complex 2 subunit involved_in ISO UniProtKB:P38827 (PMID:9214638) RGD PMID:9214638 NCBI chr 4:76,624,399...76,687,362
Ensembl chr 4:76,624,399...76,687,362 		JBrowse link
G H3f3a H3.3 histone A acts_upstream_of_or_within ISO MGI:1101768 (PMID:26159997) RGD PMID:26159997 NCBI chr13:92,533,289...92,544,902
Ensembl chr13:92,533,298...92,544,908 		JBrowse link
G H3f3b H3.3 histone B acts_upstream_of_or_within ISO MGI:1097686 (PMID:26159997) RGD PMID:26159997 NCBI chr10:101,256,484...101,258,716
Ensembl chr10:101,256,480...101,258,709 		JBrowse link
G Hat1 histone acetyltransferase 1 involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 3:56,217,344...56,265,021
Ensembl chr 3:56,217,342...56,275,517 		JBrowse link
G Rif1 replication timing regulatory factor 1 involved_in ISO (MGI:5584328|PMID:24735877) RGD PMID:24735877 MGI:5584328 NCBI chr 3:36,554,689...36,607,961
Ensembl chr 3:36,554,697...36,603,617 		JBrowse link
G Sirt6 sirtuin 6 involved_in ISO (PMID:21847107) RGD PMID:21847107 NCBI chr 7:8,082,312...8,087,776
Ensembl chr 7:8,082,364...8,098,914 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20413
    metabolic process 11835
      negative regulation of metabolic process 3098
        negative regulation of macromolecule metabolic process 2865
          negative regulation of macromolecule biosynthetic process 2478
            negative regulation of gene expression 1382
              negative regulation of gene expression, epigenetic 180
                heterochromatin formation 148
                  constitutive heterochromatin formation + 11
                  dosage compensation by inactivation of X chromosome + 19
                  facultative heterochromatin formation + 52
                  heterochromatin boundary formation 2
                  negative regulation of heterochromatin formation + 6
                  pericentric heterochromatin organization 2
                  positive regulation of heterochromatin formation + 14
                  regulation of heterochromatin formation + 25
                  regulatory ncRNA-mediated heterochromatin formation + 13
Path 2
Term Annotations click to browse term
  biological_process 20413
    biological regulation 13755
      regulation of biological process 13322
        regulation of metabolic process 6641
          regulation of biosynthetic process 5478
            regulation of cellular biosynthetic process 5386
              regulation of macromolecule biosynthetic process 5286
                regulation of gene expression 5170
                  negative regulation of gene expression 1382
                    negative regulation of gene expression, epigenetic 180
                      heterochromatin formation 148
                        constitutive heterochromatin formation + 11
                        dosage compensation by inactivation of X chromosome + 19
                        facultative heterochromatin formation + 52
                        heterochromatin boundary formation 2
                        negative regulation of heterochromatin formation + 6
                        pericentric heterochromatin organization 2
                        positive regulation of heterochromatin formation + 14
                        regulation of heterochromatin formation + 25
                        regulatory ncRNA-mediated heterochromatin formation + 13
paths to the root