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ONTOLOGY REPORT - ANNOTATIONS


Term:heterochromatin assembly
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Accession:GO:0031507 term browser browse the term
Definition:An epigenetic gene silencing mechanism that involves the assembly of chromatin into heterochromatin, resulting in a chromatin conformation refractory to transcription. This process starts with heterochromatin nucleation, its spreading, and ends with heterochromatin boundary formation.
Synonyms:exact_synonym: chromatin silencing;   chromatin-mediated silencing;   establishment of heterochromatin architecture;   heterochromatin formation;   transcriptional gene silencing
 narrow_synonym: establishment of heterochromatin architecture involved in chromatin silencing at centromere outer repeat region;   establishment of heterochromatin architecture involved in chromatin silencing at pericentric region;   heterochromatin assembly involved in chromatin silencing at centromere outer repeat region;   heterochromatin assembly involved in chromatin silencing at pericentric region;   heterochromatin formation involved in chromatin silencing at centromere outer repeat region;   heterochromatin formation involved in chromatin silencing at pericentric region
 broad_synonym: TGS;   heterochromatin maintenance
 related_synonym: establishment of chromatin silencing;   establishment of heterochromatic silencing;   heterochromatic silencing;   heterochromatin assembly involved in chromatin silencing;   heterochromatin formation involved in chromatin silencing
 alt_id: GO:0006342;   GO:0006343;   GO:0016440;   GO:0070869;   GO:1904497



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heterochromatin assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AABR07027368.1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 Ensembl chr17:26,135,927...26,136,235 JBrowse link
G Bahd1 bromo adjacent homology domain containing 1 involved_in ISO
IBA
(PMID:19666599)
PMID:21873635
RGD PMID:19666599 PMID:21873635 RGD:13792537 NCBI chr 3:105,891,207...105,914,414
Ensembl chr 3:105,892,478...105,914,410
JBrowse link
G Baz2a bromodomain adjacent to zinc finger domain, 2A acts_upstream_of_or_within ISO (MGI:3653583|PMID:16678107), (MGI:4462332|PMID:20168299) RGD PMID:16678107 PMID:20168299 MGI:3653583 MGI:4462332 NCBI chr 7:523,204...560,911
Ensembl chr 7:523,265...560,659
JBrowse link
G Cbx3 chromobox 3 involved_in ISO (PMID:17540172) RGD PMID:17540172 NCBI chr 4:80,545,450...80,559,284
Ensembl chr 4:80,546,010...80,559,283
JBrowse link
G Ctbp1 C-terminal binding protein 1 involved_in ISO
IEA
(PMID:21102443)
GO_REF:0000107
RGD
Ensembl
PMID:21102443 GO_REF:0000107 NCBI chr14:77,455,580...77,482,821
Ensembl chr14:77,455,696...77,482,821
JBrowse link
G Dot1l DOT1 like histone lysine methyltransferase involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 7:8,917,786...8,959,474
Ensembl chr 7:8,917,786...8,956,475
JBrowse link
G Ezh1 enhancer of zeste 1 polycomb repressive complex 2 subunit involved_in ISO
IBA
(MGI:3820717|PMID:19026781)
PMID:21873635
RGD PMID:19026781 PMID:21873635 MGI:3820717, RGD:13792537 NCBI chr10:86,126,023...86,162,001
Ensembl chr10:86,126,015...86,161,921
JBrowse link
G Ezh2 enhancer of zeste 2 polycomb repressive complex 2 subunit involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 4:76,624,399...76,687,362
Ensembl chr 4:76,624,399...76,687,362
JBrowse link
G H1f0 H1.0 linker histone involved_in ISO UniProtKB:P09429 (PMID:19158276) RGD PMID:19158276 NCBI chr 7:110,592,834...110,594,694
Ensembl chr 7:110,592,208...110,594,694
JBrowse link
G Hells helicase, lymphoid specific acts_upstream_of_or_within ISO MGI:2178586 (MGI:3510059|PMID:15448183) RGD PMID:15448183 MGI:3510059 NCBI chr 1:236,701,704...236,748,239
Ensembl chr 1:236,701,758...236,746,844
JBrowse link
G Hils1 histone linker H1 domain, spermatid-specific 1 involved_in ISO (PMID:12920187) RGD PMID:12920187 NCBI chr10:79,913,525...79,914,321
Ensembl chr10:79,913,480...79,914,321
JBrowse link
G Hmga2 high mobility group AT-hook 2 involved_in ISS
ISO
GO_REF:0000024
(PMID:16901784)
UniProt
RGD
PMID:16901784 GO_REF:0000024 NCBI chr 7:55,877,145...55,998,813
Ensembl chr 7:55,880,112...55,994,784
JBrowse link
G Hmgb1 high mobility group box 1 involved_in ISO UniProtKB:P07305 (PMID:19158276) RGD PMID:19158276 NCBI chr12:5,973,062...5,978,565
Ensembl chr12:5,901,586...5,978,565
JBrowse link
G Kmt2d lysine methyltransferase 2D involved_in ISO (MGI:4849597|PMID:20808952) RGD PMID:20808952 MGI:4849597 NCBI chr 7:129,980,744...130,022,088
Ensembl chr 7:129,962,887...130,020,325
JBrowse link
G L3mbtl1 L3MBTL histone methyl-lysine binding protein 1 involved_in ISO (PMID:17540172) RGD PMID:17540172 NCBI chr 3:151,597,903...151,633,657
Ensembl chr 3:151,602,980...151,631,233
JBrowse link
G Lmna lamin A/C involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 2:173,939,751...173,960,423
Ensembl chr 2:173,939,751...173,960,423
JBrowse link
G Lmnb1 lamin B1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr18:50,175,861...50,215,210
Ensembl chr18:50,175,874...50,214,502
JBrowse link
G Lmnb2 lamin B2 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 7:8,792,628...8,808,665
Ensembl chr 7:8,789,314...8,808,665
JBrowse link
G LOC100362333 DNA-directed DNA polymerase epsilon 3 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 7:109,236,160...109,236,825
Ensembl chr 7:109,236,321...109,236,758
JBrowse link
G Mecp2 methyl CpG binding protein 2 acts_upstream_of_or_within ISO MGI:2137311 (MGI:3530434|PMID:15608638) RGD PMID:15608638 MGI:3530434 NCBI chr  X:151,781,177...151,844,687
Ensembl chr  X:151,789,930...151,844,689
JBrowse link
G Pole3 DNA polymerase epsilon 3, accessory subunit involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 5:75,973,941...75,977,175
Ensembl chr 5:75,974,717...75,977,231
JBrowse link
G Ppm1d protein phosphatase, Mg2+/Mn2+ dependent, 1D involved_in ISO (MGI:5551345|PMID:24135283) RGD PMID:24135283 MGI:5551345 NCBI chr10:70,172,603...70,208,607
Ensembl chr10:70,172,603...70,208,607
JBrowse link
G Rb1 RB transcriptional corepressor 1 involved_in ISO
IEA
(PMID:17540172)
GO_REF:0000107
RGD
Ensembl
PMID:17540172 GO_REF:0000107 NCBI chr15:48,371,295...48,502,473
Ensembl chr15:48,371,296...48,502,302
JBrowse link
G RGD1560349 similar to histone-fold protein CHRAC17 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr17:26,135,927...26,136,417 JBrowse link
G Sirt1 sirtuin 1 involved_in ISO (PMID:15469825) RGD PMID:15469825 NCBI chr20:25,307,143...25,329,260
Ensembl chr20:25,306,917...25,329,260
JBrowse link
G Smarca5 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5 involved_in ISO (MGI:3653583|PMID:16678107) RGD PMID:16678107 MGI:3653583 NCBI chr19:27,271,918...27,304,594
Ensembl chr19:27,271,148...27,304,594
JBrowse link
G Spty2d1 SPT2 chromatin protein domain containing 1 involved_in ISO (PMID:26109053) RGD PMID:26109053 NCBI chr 1:97,531,495...97,549,633
Ensembl chr 1:97,531,508...97,549,581
JBrowse link
G Tnp1 transition protein 1 involved_in ISO
ISS
(PMID:11315969)
GO_REF:0000024
RGD
UniProt
PMID:11315969 GO_REF:0000024 NCBI chr 9:74,594,463...74,595,072
Ensembl chr 9:74,594,466...74,595,274
JBrowse link
G Ubr2 ubiquitin protein ligase E3 component n-recognin 2 involved_in ISO (MGI:4431162|PMID:20080676) RGD PMID:20080676 MGI:4431162 NCBI chr 9:13,982,427...14,062,315
Ensembl chr 9:13,982,329...14,062,139
JBrowse link
G Uty ubiquitously transcribed tetratricopeptide repeat containing, Y-linked acts_upstream_of_or_within ISO (MGI:5305502|PMID:22192413) RGD PMID:22192413 MGI:5305502 NCBI chr  Y:942,838...1,105,313
Ensembl chr  Y:924,168...1,103,422
JBrowse link
DNA methylation-dependent heterochromatin assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dnmt1 DNA methyltransferase 1 involved_in ISO
IEA
(MGI:3687778|PMID:10615135)
GO_REF:0000107
RGD
Ensembl
PMID:10615135 GO_REF:0000107 MGI:3687778 NCBI chr 8:19,440,611...19,486,659
Ensembl chr 8:19,440,611...19,486,659
JBrowse link
G Dnmt3a DNA methyltransferase 3 alpha acts_upstream_of_or_within ISO MGI:1261819 (MGI:3611125|PMID:16322236), (MGI:3768461|PMID:17938196) RGD PMID:16322236 PMID:17938196 MGI:3611125 MGI:3768461 NCBI chr 6:26,791,517...26,902,161
Ensembl chr 6:26,822,609...26,896,687
JBrowse link
G Dnmt3b DNA methyltransferase 3 beta acts_upstream_of_or_within ISO MGI:1261827 (MGI:3768461|PMID:17938196) RGD PMID:17938196 MGI:3768461 NCBI chr 3:142,130,592...142,169,124
Ensembl chr 3:142,130,592...142,169,124
JBrowse link
G Hdac1 histone deacetylase 1 involved_in ISO UniProtKB:Q9UBB5 (PMID:23770133) RGD PMID:23770133 NCBI chr 5:141,853,992...141,881,057
Ensembl chr 5:141,853,989...141,881,111
JBrowse link
G Hells helicase, lymphoid specific involved_in IBA
ISO
PMID:21873635
(MGI:3573964|PMID:15647320)
RGD PMID:15647320 PMID:21873635 MGI:3573964, RGD:13792537 NCBI chr 1:236,701,704...236,748,239
Ensembl chr 1:236,701,758...236,746,844
JBrowse link
G Kmt2b lysine methyltransferase 2B acts_upstream_of_or_within ISO MGI:3056522|MGI:3623309 (MGI:4849597|PMID:20808952) RGD PMID:20808952 MGI:4849597 NCBI chr 1:85,821,700...85,840,987
Ensembl chr 1:85,821,753...85,841,326
JBrowse link
G Mbd2 methyl-CpG binding domain protein 2 involved_in ISO UniProtKB:Q13547 (PMID:23770133) RGD PMID:23770133 NCBI chr18:64,174,002...64,240,795
Ensembl chr18:64,174,002...64,240,794
JBrowse link
G Mbd3 methyl-CpG binding domain protein 3 acts_upstream_of_or_within ISO (MGI:3611125|PMID:16322236) RGD PMID:16322236 MGI:3611125 NCBI chr 7:9,312,961...9,320,166
Ensembl chr 7:9,313,098...9,320,165
JBrowse link
G Smarca4 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 acts_upstream_of_or_within ISO (MGI:3611125|PMID:16322236) RGD PMID:16322236 MGI:3611125 NCBI chr 8:20,167,717...20,258,975
Ensembl chr 8:20,167,717...20,258,975
JBrowse link
genomic imprinting term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Asip agouti signaling protein acts_upstream_of_or_within
involved_in
ISO
IEA
MGI:1855930|MGI:1855937 (MGI:2652932|PMID:12601169)
GO_REF:0000107
RGD
Ensembl
PMID:12601169 GO_REF:0000107 MGI:2652932 NCBI chr 3:143,473,584...143,561,170
Ensembl chr 3:143,555,696...143,561,171
JBrowse link
G Axin1 axin 1 acts_upstream_of_or_within ISO MGI:1856035 (MGI:2652932|PMID:12601169) RGD PMID:12601169 MGI:2652932 NCBI chr10:15,163,684...15,215,615
Ensembl chr10:15,163,684...15,215,615
JBrowse link
G Cdkn1c cyclin-dependent kinase inhibitor 1C acts_upstream_of_or_within ISO MGI:1933758|MGI:3840687 (MGI:3839493|PMID:19276117) RGD PMID:19276117 MGI:3839493 NCBI chr 1:198,655,394...198,658,097
Ensembl chr 1:198,655,407...198,658,048
JBrowse link
G Ctcf CCCTC-binding factor involved_in ISO (PMID:17827499) RGD PMID:17827499 NCBI chr19:33,521,726...33,571,124
Ensembl chr19:33,529,319...33,571,123
JBrowse link
G Dnmt3l DNA methyltransferase 3 like acts_upstream_of_or_within ISO MGI:2447127 (MGI:3663953|PMID:16920095) RGD PMID:16920095 MGI:3663953 NCBI chr20:10,614,933...10,629,516
Ensembl chr20:10,614,934...10,629,516
JBrowse link
G Gnas GNAS complex locus acts_upstream_of_or_within ISO MGI:4459474 (MGI:4454202|PMID:20427744) RGD PMID:20427744 MGI:4454202 NCBI chr 3:163,071,003...163,136,350
Ensembl chr 3:163,071,417...163,127,262
Ensembl chr 3:163,071,417...163,127,262
JBrowse link
G Ndn necdin, MAGE family member acts_upstream_of_or_within ISO MGI:2653045|MGI:2653048 (MGI:1345919|PMID:10508517) RGD PMID:10508517 MGI:1345919 NCBI chr 1:115,849,168...115,850,767
Ensembl chr 1:115,849,105...115,850,767
JBrowse link
G Zdbf2 zinc finger, DBF-type containing 2 acts_upstream_of_or_within
involved_in
ISO
IBA
MGI:6161219 (MGI:6151717|PMID:27841881)
PMID:21873635
RGD PMID:27841881 PMID:21873635 MGI:6151717, RGD:13792537 NCBI chr 9:64,672,974...64,748,446
Ensembl chr 9:64,709,880...64,744,265
JBrowse link
G Zfp57 zinc finger protein 57 acts_upstream_of_or_within ISO MGI:3826984 (MGI:6506156|PMID:33500348) RGD PMID:33500348 MGI:6506156 NCBI chr20:1,521,323...1,534,884
Ensembl chr20:1,521,323...1,529,846
JBrowse link
heterochromatin assembly by small RNA term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fam172a family with sequence similarity 172, member A involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 2:7,553,873...8,018,183
Ensembl chr 2:7,553,891...8,018,162
JBrowse link
G Znfx1 zinc finger, NFX1-type containing 1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 3:155,764,073...155,791,777
Ensembl chr 3:155,764,980...155,821,242
JBrowse link
inactivation of X chromosome by heterochromatin assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Smchd1 structural maintenance of chromosomes flexible hinge domain containing 1 involved_in ISO (MGI:5532809|PMID:23754746) RGD PMID:23754746 MGI:5532809 NCBI chr 9:111,243,445...111,387,272
Ensembl chr 9:111,247,702...111,349,665
JBrowse link
negative regulation of DNA methylation-dependent heterochromatin assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aicda activation-induced cytidine deaminase involved_in ISO (PMID:21496894) RGD PMID:21496894 NCBI chr 4:155,774,132...155,783,972
Ensembl chr 4:155,774,132...155,783,972
JBrowse link
G Apobec1 apolipoprotein B mRNA editing enzyme catalytic subunit 1 involved_in ISS
ISO
GO_REF:0000024
(MGI:5285126|PMID:21496894)
UniProt
RGD
PMID:21496894 GO_REF:0000024 MGI:5285126 NCBI chr 4:155,800,030...155,828,515
Ensembl chr 4:155,800,887...155,827,390
JBrowse link
G Tet1 tet methylcytosine dioxygenase 1 involved_in ISO (PMID:21496894) RGD PMID:21496894 NCBI chr20:25,761,042...25,840,926
Ensembl chr20:25,768,120...25,833,052
JBrowse link
negative regulation of ribosomal DNA heterochromatin assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Phf2 PHD finger protein 2 involved_in ISO (PMID:20129925) RGD PMID:20129925 NCBI chr17:15,783,221...15,851,209
Ensembl chr17:15,781,864...15,851,208
JBrowse link
G Phf8 PHD finger protein 8 involved_in ISO (PMID:20208542) RGD PMID:20208542 NCBI chr  X:20,524,103...20,623,459
Ensembl chr  X:20,524,558...20,623,410
JBrowse link
pericentric heterochromatin assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cenpv centromere protein V involved_in ISO
IBA
(PMID:18772885)
PMID:21873635
RGD PMID:18772885 PMID:21873635 RGD:13792537 NCBI chr10:47,214,479...47,228,552
Ensembl chr10:47,214,490...47,228,761
JBrowse link
G Dicer1 dicer 1 ribonuclease III acts_upstream_of_or_within ISO MGI:3589287 (MGI:3528782|PMID:15713842) RGD PMID:15713842 MGI:3528782 NCBI chr 6:123,627,529...123,692,278
Ensembl chr 6:123,631,250...123,693,965
JBrowse link
G H3f3a H3.3 histone A acts_upstream_of_or_within ISO MGI:1101768 (MGI:5694896|PMID:26159997) RGD PMID:26159997 MGI:5694896 NCBI chr13:92,533,294...92,544,903
Ensembl chr13:92,533,298...92,544,908
JBrowse link
G H3f3b H3.3 histone B acts_upstream_of_or_within ISO MGI:1097686 (MGI:5694896|PMID:26159997) RGD PMID:26159997 MGI:5694896 NCBI chr10:101,256,488...101,258,712
Ensembl chr10:101,256,480...101,258,709
JBrowse link
G Hells helicase, lymphoid specific involved_in IBA
ISO
PMID:21873635
(MGI:3041983|PMID:14612388)
RGD PMID:14612388 PMID:21873635 MGI:3041983, RGD:13792537 NCBI chr 1:236,701,704...236,748,239
Ensembl chr 1:236,701,758...236,746,844
JBrowse link
G Sirt6 sirtuin 6 involved_in ISO (PMID:27043296) RGD PMID:27043296 NCBI chr 7:8,082,312...8,087,776
Ensembl chr 7:8,082,364...8,098,914
JBrowse link
positive regulation of DNA methylation-dependent heterochromatin assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atf7ip activating transcription factor 7 interacting protein involved_in ISO
IBA
(PMID:27732843)
PMID:21873635
RGD PMID:27732843 PMID:21873635 RGD:13792537 NCBI chr 4:169,385,872...169,471,652
Ensembl chr 4:169,385,872...169,471,650
JBrowse link
G Dnmt1 DNA methyltransferase 1 involved_in ISS
IEA
ISO
GO_REF:0000024
GO_REF:0000107
(PMID:24623306)
UniProt
Ensembl
RGD
PMID:24623306 GO_REF:0000024 GO_REF:0000107 NCBI chr 8:19,440,611...19,486,659
Ensembl chr 8:19,440,611...19,486,659
JBrowse link
G LOC120093070 PHD finger protein 11-like involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr15:33,526,380...33,549,382
Ensembl chr15:33,453,952...33,606,470
JBrowse link
G LOC120093163 PHD finger protein 11-like involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr15:33,453,948...33,475,669
Ensembl chr15:33,453,952...33,606,470
JBrowse link
G Morc2 MORC family CW-type zinc finger 2 involved_in ISO (PMID:28581500), (PMID:29211708)
(MGI:6271895|PMID:29728365)
RGD PMID:28581500 PMID:29211708 PMID:29728365 MGI:6271895 NCBI chr14:78,529,603...78,571,375
Ensembl chr14:78,527,009...78,571,343
JBrowse link
G Mphosph8 M-phase phosphoprotein 8 involved_in ISS
ISO
GO_REF:0000024
(PMID:28581500), (PMID:29211708)
UniProt
RGD
PMID:28581500 PMID:29211708 GO_REF:0000024 NCBI chr15:30,800,546...30,828,415
Ensembl chr15:30,686,613...30,828,810
JBrowse link
G Pphln1 periphilin 1 involved_in ISO (PMID:28581500) RGD PMID:28581500 NCBI chr 7:124,538,594...124,629,985
Ensembl chr 7:124,538,627...124,629,985
JBrowse link
G Resf1 retroelement silencing factor 1 involved_in ISO
IBA
(MGI:6271895|PMID:29728365)
PMID:21873635
RGD PMID:29728365 PMID:21873635 MGI:6271895, RGD:13792537 NCBI chr 4:182,325,913...182,362,054
Ensembl chr 4:182,335,454...182,362,054
JBrowse link
G Setdb1 SET domain bifurcated histone lysine methyltransferase 1 involved_in IBA
ISO
PMID:21873635
(MGI:5440670|PMID:20164836), (MGI:6271895|PMID:29728365)
(PMID:24623306), (PMID:27732843)
RGD PMID:20164836 PMID:24623306 PMID:27732843 PMID:29728365 PMID:21873635 MGI:5440670 MGI:6271895, RGD:13792537 NCBI chr 2:182,898,738...182,930,283
Ensembl chr 2:182,898,738...182,930,506
JBrowse link
G Setdb2 SET domain bifurcated histone lysine methyltransferase 2 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr15:33,553,657...33,606,586
Ensembl chr15:33,453,952...33,606,470
JBrowse link
G Tasor transcription activation suppressor involved_in ISO
IBA
(PMID:28581500), (PMID:29211708)
PMID:21873635
RGD PMID:28581500 PMID:29211708 PMID:21873635 RGD:13792537 NCBI chr16:2,606,807...2,669,902
Ensembl chr16:2,603,936...2,667,292
JBrowse link
G Trim28 tripartite motif-containing 28 involved_in ISS
ISO
GO_REF:0000024
(MGI:5440670|PMID:20164836)
(PMID:24623306)
UniProt
RGD
PMID:20164836 PMID:24623306 GO_REF:0000024 MGI:5440670 NCBI chr 1:73,652,441...73,659,388
Ensembl chr 1:73,652,709...73,659,380
JBrowse link
positive regulation of heterochromatin assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cdk2 cyclin dependent kinase 2 involved_in ISO (PMID:20935635) RGD PMID:20935635 NCBI chr 7:1,129,878...1,137,431
Ensembl chr 7:1,129,811...1,137,403
JBrowse link
G Sin3a SIN3 transcription regulator family member A involved_in ISO (PMID:22783022) RGD PMID:22783022 NCBI chr 8:57,481,539...57,536,195
Ensembl chr 8:57,481,573...57,536,192
JBrowse link
G Tpr translocated promoter region, nuclear basket protein involved_in ISO
ISS
(PMID:20407419)
GO_REF:0000024
RGD
UniProt
PMID:20407419 GO_REF:0000024 NCBI chr13:62,424,312...62,487,502
Ensembl chr13:62,424,312...62,487,496
JBrowse link
rDNA heterochromatin assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Baz2a bromodomain adjacent to zinc finger domain, 2A involved_in
acts_upstream_of_or_within
ISO (MGI:3587127|PMID:16085498), (MGI:3852313|PMID:12198165), (MGI:3852588|PMID:19578370)
(MGI:3653583|PMID:16678107), (MGI:4462332|PMID:20168299)
RGD PMID:12198165 PMID:16085498 PMID:16678107 PMID:19578370 PMID:20168299 MGI:3587127 MGI:3653583 MGI:3852313 MGI:3852588 MGI:4462332 NCBI chr 7:523,204...560,911
Ensembl chr 7:523,265...560,659
JBrowse link
G Bend3 BEN domain containing 3 involved_in ISO
IBA
(PMID:26100909)
PMID:21873635
RGD PMID:26100909 PMID:21873635 RGD:13792537 NCBI chr20:46,980,246...47,017,059
Ensembl chr20:46,979,831...47,014,671
JBrowse link
G Rrp8 ribosomal RNA processing 8 involved_in ISS
ISO
IBA
GO_REF:0000024
(PMID:18485871)
PMID:21873635
UniProt
RGD
PMID:18485871 PMID:21873635 GO_REF:0000024, RGD:13792537 NCBI chr 1:160,081,092...160,088,709
Ensembl chr 1:160,084,295...160,089,331
JBrowse link
G Sirt1 sirtuin 1 involved_in ISO (PMID:18485871) RGD PMID:18485871 NCBI chr20:25,307,143...25,329,260
Ensembl chr20:25,306,917...25,329,260
JBrowse link
G Smarca5 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5 involved_in ISO (MGI:3587127|PMID:16085498), (MGI:3852313|PMID:12198165) RGD PMID:12198165 PMID:16085498 MGI:3587127 MGI:3852313 NCBI chr19:27,271,918...27,304,594
Ensembl chr19:27,271,148...27,304,594
JBrowse link
G Suv39h1 SUV39H1 histone lysine methyltransferase involved_in ISO (PMID:18485871) RGD PMID:18485871 NCBI chr  X:14,421,028...14,434,216
Ensembl chr  X:14,421,109...14,433,982
JBrowse link
G Suv39h1-ps1 SUV39H1 histone lysine methyltransferase, pseudogene 1 involved_in ISO (PMID:18485871) RGD PMID:18485871 NCBI chr  X:141,793,695...141,795,558 JBrowse link
G Ubtf upstream binding transcription factor acts_upstream_of_or_within ISO (MGI:3836497|PMID:19103806) RGD PMID:19103806 MGI:3836497 NCBI chr10:87,258,217...87,274,291
Ensembl chr10:87,258,217...87,272,969
JBrowse link
regulation of DNA methylation-dependent heterochromatin assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Kdm1a lysine demethylase 1A involved_in ISO (PMID:33980486) RGD PMID:33980486 NCBI chr 5:148,782,976...148,838,319
Ensembl chr 5:148,782,976...148,838,319
JBrowse link
G L3mbtl3 L3MBTL histone methyl-lysine binding protein 3 involved_in ISO (PMID:33980486) RGD PMID:33980486 NCBI chr 1:18,988,763...19,089,247
Ensembl chr 1:18,990,618...19,089,263
JBrowse link
G Pou5f1 POU class 5 homeobox 1 involved_in ISO (PMID:19736317) RGD PMID:19736317 NCBI chr20:3,223,128...3,227,891
Ensembl chr20:3,223,129...3,227,891
JBrowse link
G Samd1 sterile alpha motif domain containing 1 involved_in ISO (PMID:33980486) RGD PMID:33980486 NCBI chr19:24,151,136...24,154,475
Ensembl chr19:24,151,128...24,154,488
JBrowse link
regulation of genetic imprinting term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ctr9 CTR9 homolog, Paf1/RNA polymerase II complex component acts_upstream_of_or_within ISO (MGI:5528755|PMID:24036311) RGD PMID:24036311 MGI:5528755 NCBI chr 1:165,137,277...165,167,303
Ensembl chr 1:165,137,215...165,167,303
JBrowse link
G Dppa3 developmental pluripotency-associated 3 involved_in IBA
ISO
ISS
PMID:21873635
(MGI:5432962|PMID:22722204), (MGI:5447615|PMID:17143267)
GO_REF:0000024
RGD
UniProt
PMID:17143267 PMID:22722204 PMID:21873635 GO_REF:0000024 MGI:5432962 MGI:5447615, RGD:13792537 NCBI chr 4:155,851,461...155,854,845
Ensembl chr 4:155,815,296...155,854,861
JBrowse link
G Dppa3l1 developmental pluripotency associated 3-like 1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 8:56,421,825...56,422,277
Ensembl chr 8:56,421,825...56,422,277
JBrowse link
G LOC120096627 developmental pluripotency-associated protein 3-like involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr14:69,456,777...69,460,079
Ensembl chr14:69,457,383...69,457,859
JBrowse link
G LOC120096971 developmental pluripotency-associated protein 3-like involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr15:27,224,329...27,232,700
Ensembl chr15:27,225,434...27,225,910
JBrowse link
G Pik3ca phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha involved_in ISO (MGI:5009774|PMID:21047779) RGD PMID:21047779 MGI:5009774 NCBI chr 2:115,175,275...115,249,034
Ensembl chr 2:115,174,984...115,249,032
JBrowse link
G Tet1 tet methylcytosine dioxygenase 1 acts_upstream_of_or_within ISO MGI:4129024 (MGI:5559953|PMID:24291790) RGD PMID:24291790 MGI:5559953 NCBI chr20:25,761,042...25,840,926
Ensembl chr20:25,768,120...25,833,052
JBrowse link
G Trim28 tripartite motif-containing 28 acts_upstream_of_or_within ISO MGI:1928907 (MGI:5319411|PMID:22495301) RGD PMID:22495301 MGI:5319411 NCBI chr 1:73,652,441...73,659,388
Ensembl chr 1:73,652,709...73,659,380
JBrowse link
G Zfp42 zinc finger protein 42 acts_upstream_of_or_within ISO MGI:4125334 (MGI:4940138|PMID:21233130) RGD PMID:21233130 MGI:4940138 NCBI chr16:48,836,463...48,845,443
Ensembl chr16:48,836,648...48,845,401
JBrowse link
G Zfp445 zinc finger protein 445 involved_in ISO (PMID:30602440)
UniProtKB:Q8C6P8 (MGI:6284037|PMID:30602440)
RGD PMID:30602440 MGI:6284037 NCBI chr 8:122,453,175...122,473,355
Ensembl chr 8:122,454,328...122,473,286
JBrowse link
G Zfp57 zinc finger protein 57 involved_in ISO UniProtKB:Q8R2V3 (MGI:6284037|PMID:30602440) RGD PMID:30602440 MGI:6284037 NCBI chr20:1,521,323...1,534,884
Ensembl chr20:1,521,323...1,529,846
JBrowse link
regulation of heterochromatin assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Baz1a bromodomain adjacent to zinc finger domain, 1A involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 6:72,389,701...72,512,516
Ensembl chr 6:72,389,703...72,512,459
JBrowse link
regulation of ribosomal DNA heterochromatin assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Macroh2a1 macroH2A.1 histone NOT|involved_in ISO (PMID:24071584) RGD PMID:24071584 NCBI chr17:8,479,331...8,542,071
Ensembl chr17:8,479,372...8,542,072
JBrowse link
subtelomeric heterochromatin assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ezh1 enhancer of zeste 1 polycomb repressive complex 2 subunit involved_in ISO UniProtKB:P38827 (MGI:892875|PMID:9214638) RGD PMID:9214638 MGI:892875 NCBI chr10:86,126,023...86,162,001
Ensembl chr10:86,126,015...86,161,921
JBrowse link
G Ezh2 enhancer of zeste 2 polycomb repressive complex 2 subunit involved_in ISO UniProtKB:P38827 (PMID:9214638) RGD PMID:9214638 NCBI chr 4:76,624,399...76,687,362
Ensembl chr 4:76,624,399...76,687,362
JBrowse link
G H3f3a H3.3 histone A acts_upstream_of_or_within ISO MGI:1101768 (MGI:5694896|PMID:26159997) RGD PMID:26159997 MGI:5694896 NCBI chr13:92,533,294...92,544,903
Ensembl chr13:92,533,298...92,544,908
JBrowse link
G H3f3b H3.3 histone B acts_upstream_of_or_within ISO MGI:1097686 (MGI:5694896|PMID:26159997) RGD PMID:26159997 MGI:5694896 NCBI chr10:101,256,488...101,258,712
Ensembl chr10:101,256,480...101,258,709
JBrowse link
G Hat1 histone acetyltransferase 1 involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 3:56,217,344...56,265,021
Ensembl chr 3:56,217,342...56,275,517
JBrowse link
G Rif1 replication timing regulatory factor 1 involved_in ISO (MGI:5584328|PMID:24735877) RGD PMID:24735877 MGI:5584328 NCBI chr 3:36,554,689...36,607,961
Ensembl chr 3:36,554,697...36,603,617
JBrowse link
G Sirt6 sirtuin 6 involved_in ISO (PMID:21847107) RGD PMID:21847107 NCBI chr 7:8,082,312...8,087,776
Ensembl chr 7:8,082,364...8,098,914
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 18734
    metabolic process 11458
      negative regulation of metabolic process 3297
        negative regulation of macromolecule metabolic process 3065
          negative regulation of gene expression 1262
            negative regulation of gene expression, epigenetic 103
              heterochromatin assembly 95
                constitutive heterochromatin assembly + 11
                facultative heterochromatin assembly + 38
                genomic imprinting + 19
                heterochromatin assembly by small RNA + 2
                heterochromatin boundary formation 0
                negative regulation of heterochromatin assembly + 5
                positive regulation of heterochromatin assembly + 15
                pre-transcriptional gene silencing by RNA + 0
                regulation of heterochromatin assembly + 35
Path 2
Term Annotations click to browse term
  biological_process 18734
    cellular process 17431
      cellular component organization or biogenesis 6532
        cellular component organization 6307
          organelle organization 3900
            chromosome organization 969
              chromatin organization 537
                regulation of gene expression, epigenetic 176
                  negative regulation of gene expression, epigenetic 103
                    heterochromatin assembly 95
                      constitutive heterochromatin assembly + 11
                      facultative heterochromatin assembly + 38
                      genomic imprinting + 19
                      heterochromatin assembly by small RNA + 2
                      heterochromatin boundary formation 0
                      negative regulation of heterochromatin assembly + 5
                      positive regulation of heterochromatin assembly + 15
                      pre-transcriptional gene silencing by RNA + 0
                      regulation of heterochromatin assembly + 35
paths to the root