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ONTOLOGY REPORT - ANNOTATIONS


Term:heterochromatin assembly
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Accession:GO:0031507 term browser browse the term
Definition:An epigenetic gene silencing mechanism that involves the assembly of chromatin into heterochromatin, resulting in a chromatin conformation refractory to transcription. This process starts with heterochromatin nucleation, its spreading, and ends with heterochromatin boundary formation.
Synonyms:exact_synonym: chromatin silencing;   chromatin-mediated silencing;   establishment of heterochromatin architecture;   heterochromatin formation;   transcriptional gene silencing
 narrow_synonym: establishment of heterochromatin architecture involved in chromatin silencing at centromere outer repeat region;   establishment of heterochromatin architecture involved in chromatin silencing at pericentric region;   heterochromatin assembly involved in chromatin silencing at centromere outer repeat region;   heterochromatin assembly involved in chromatin silencing at pericentric region;   heterochromatin formation involved in chromatin silencing at centromere outer repeat region;   heterochromatin formation involved in chromatin silencing at pericentric region
 broad_synonym: TGS;   heterochromatin maintenance
 related_synonym: establishment of chromatin silencing;   establishment of heterochromatic silencing;   heterochromatic silencing;   heterochromatin assembly involved in chromatin silencing;   heterochromatin formation involved in chromatin silencing
 alt_id: GO:0006342;   GO:0006343;   GO:0016440;   GO:0070869;   GO:1904497


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heterochromatin assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AABR07027368.1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 Ensembl chr17:26,135,927...26,136,235 JBrowse link
G AABR07062859.1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537
G Bahd1 bromo adjacent homology domain containing 1 involved_in ISO (PMID:19666599) RGD PMID:19666599 NCBI chr 3:105,891,207...105,914,414
Ensembl chr 3:105,892,478...105,914,410
JBrowse link
G Baz2a bromodomain adjacent to zinc finger domain, 2A acts_upstream_of_or_within ISO (MGI:3653583|PMID:16678107), (MGI:4462332|PMID:20168299) RGD PMID:16678107 PMID:20168299 MGI:3653583 MGI:4462332 NCBI chr 7:523,204...560,911
Ensembl chr 7:523,265...560,659
JBrowse link
G Bmi1 BMI1 proto-oncogene, polycomb ring finger involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr17:81,332,175...81,341,625
Ensembl chr17:81,332,214...81,388,690
JBrowse link
G Ctbp1 C-terminal binding protein 1 involved_in IEA
ISO
GO_REF:0000107
(PMID:21102443)
Ensembl
RGD
PMID:21102443 GO_REF:0000107 NCBI chr14:77,455,580...77,482,821
Ensembl chr14:77,455,696...77,482,821
JBrowse link
G Eed embryonic ectoderm development involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 1:143,867,875...143,895,008
Ensembl chr 1:143,867,875...143,894,974
JBrowse link
G Ezh1 enhancer of zeste 1 polycomb repressive complex 2 subunit involved_in ISO (MGI:3820717|PMID:19026781) RGD PMID:19026781 MGI:3820717 NCBI chr10:86,126,023...86,162,001
Ensembl chr10:86,126,015...86,161,921
JBrowse link
G H2ab3 H2A.B variant histone 3 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr  X:82,362,633...82,362,983
Ensembl chr  X:82,362,633...82,362,983
JBrowse link
G H2ac1 H2A clustered histone 1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr17:41,171,384...41,171,776
Ensembl chr17:41,135,489...41,172,022
JBrowse link
G H2ac12 H2A clustered histone 12 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr17:42,486,315...42,486,880 JBrowse link
G H2ac20 H2A clustered histone 20 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 2:183,779,879...183,780,324 JBrowse link
G H2ac21 H2A clustered histone 21 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 2:183,779,385...183,779,777 JBrowse link
G H2ac4 H2A clustered histone 4 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr17:42,799,953...42,800,345
Ensembl chr17:42,799,652...42,800,381
JBrowse link
G H2aj H2A.J histone involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 4:169,675,718...169,676,202
Ensembl chr 4:169,675,752...169,677,006
JBrowse link
G H2ap H2A.P histone involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr  X:12,907,962...12,908,516 JBrowse link
G H2ax H2A.X variant histone involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 8:44,671,927...44,673,257
Ensembl chr 8:44,671,786...44,673,239
JBrowse link
G H2az1 H2A.Z variant histone 1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 2:226,355,769...226,357,878
Ensembl chr 2:226,355,708...226,358,485
JBrowse link
G H2az2 H2A.Z variant histone 2 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr14:81,293,299...81,312,209
Ensembl chr14:81,293,299...81,312,144
JBrowse link
G Hells helicase, lymphoid specific acts_upstream_of_or_within ISO MGI:2178586 (MGI:3510059|PMID:15448183) RGD PMID:15448183 MGI:3510059 NCBI chr 1:236,701,704...236,748,239
Ensembl chr 1:236,701,758...236,746,844
JBrowse link
G Hils1 histone linker H1 domain, spermatid-specific 1 involved_in ISO (PMID:12920187) RGD PMID:12920187 NCBI chr10:79,913,525...79,914,321
Ensembl chr10:79,913,480...79,914,321
JBrowse link
G Hist1h2ac histone cluster 1 H2A family member C involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr17:42,478,803...42,484,078 JBrowse link
G Hist1h2af histone cluster 1 H2A family member F involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr17:41,379,404...41,379,796
Ensembl chr17:41,379,404...41,379,796
JBrowse link
G Hist1h2ah histone cluster 1 H2A family member H involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr17:41,384,521...41,385,018 JBrowse link
G Hist1h2ai histone cluster 1, H2ai involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr17:42,718,310...42,718,772 JBrowse link
G hist1h2ail2 histone cluster 1, H2ai-like2 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr17:42,753,166...42,753,625 JBrowse link
G Hist1h2an histone cluster 1, H2an involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr17:41,534,653...41,535,259
Ensembl chr17:41,534,691...41,539,869
JBrowse link
G Hist1h2ao histone cluster 1, H2ao involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr17:42,704,740...42,705,130 JBrowse link
G Hist2h2aa2 histone cluster 2 H2A family member A2 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 2:183,801,369...183,801,987 JBrowse link
G Hist2h2aa3 histone cluster 2 H2A family member A3 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 2:183,808,398...183,808,922 JBrowse link
G Hist3h2a histone cluster 3, H2a involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr10:43,733,702...43,735,254
Ensembl chr10:43,733,668...43,744,874
JBrowse link
G Hmga2 high mobility group AT-hook 2 involved_in ISS
ISO
GO_REF:0000024
(PMID:16901784)
UniProt
RGD
PMID:16901784 GO_REF:0000024 NCBI chr 7:55,877,145...55,998,813
Ensembl chr 7:55,880,112...55,994,784
JBrowse link
G Kdm1a lysine demethylase 1A involved_in ISO (MGI:4461095|PMID:20123967) RGD PMID:20123967 MGI:4461095 NCBI chr 5:148,782,976...148,838,319
Ensembl chr 5:148,782,976...148,838,319
JBrowse link
G Kmt2d lysine methyltransferase 2D involved_in ISO (MGI:4849597|PMID:20808952) RGD PMID:20808952 MGI:4849597 NCBI chr 7:129,980,744...130,022,088
Ensembl chr 7:129,962,887...130,020,325
JBrowse link
G LOC100362333 DNA-directed DNA polymerase epsilon 3 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 7:109,236,160...109,236,825
Ensembl chr 7:109,236,321...109,236,758
JBrowse link
G LOC100363125 rCG42854-like involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr  X:12,905,312...12,905,916 JBrowse link
G LOC100910554 histone H2A type 1-like involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr17:42,696,845...42,697,423
Ensembl chr17:42,696,791...42,697,295
JBrowse link
G LOC103690190 histone H2A type 1-E involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr17:42,707,863...42,708,420 JBrowse link
G LOC680063 similar to histone 2a involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537
G LOC684773 similar to histone 2a involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr17:41,532,630...41,533,464 JBrowse link
G Macroh2a1 macroH2A.1 histone involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr17:8,479,331...8,542,071
Ensembl chr17:8,479,372...8,542,072
JBrowse link
G Macroh2a2 macroH2A.2 histone involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr20:29,678,194...29,727,867
Ensembl chr20:29,678,222...29,727,891
JBrowse link
G Mecp2 methyl CpG binding protein 2 acts_upstream_of_or_within
involved_in
ISO
IEA
MGI:2137311 (MGI:3530434|PMID:15608638)
GO_REF:0000107
RGD
Ensembl
PMID:15608638 GO_REF:0000107 MGI:3530434 NCBI chr  X:151,781,177...151,844,687
Ensembl chr  X:151,789,930...151,844,689
JBrowse link
G Morf4l1 mortality factor 4 like 1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 8:90,642,988...90,664,518
Ensembl chr 8:90,642,988...90,664,519
JBrowse link
G Morf4l2 mortality factor 4 like 2 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr  X:100,082,562...100,093,658
Ensembl chr  X:100,082,404...100,093,728
JBrowse link
G Msl3 MSL complex subunit 3 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr  X:25,638,029...25,655,698
Ensembl chr  X:25,637,804...25,655,697
JBrowse link
G Msl3l2 male-specific lethal 3-like 2 (Drosophila) involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr20:35,468,877...35,477,037
Ensembl chr20:35,468,888...35,477,757
JBrowse link
G Pcgf1 polycomb group ring finger 1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 4:115,576,165...115,587,019
Ensembl chr 4:115,583,867...115,587,008
JBrowse link
G Pcgf2 polycomb group ring finger 2 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr10:82,682,563...82,694,563
Ensembl chr10:82,683,553...82,693,406
JBrowse link
G Pole3 DNA polymerase epsilon 3, accessory subunit involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 5:75,973,941...75,977,175
Ensembl chr 5:75,974,717...75,977,231
JBrowse link
G Ppm1d protein phosphatase, Mg2+/Mn2+ dependent, 1D involved_in ISO (MGI:5551345|PMID:24135283) RGD PMID:24135283 MGI:5551345 NCBI chr10:70,172,603...70,208,607
Ensembl chr10:70,172,603...70,208,607
JBrowse link
G RGD1562306 similar to H2A histone family, member Z involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 6:6,362,973...6,363,359 JBrowse link
G RGD1562871 similar to BMI1-like protein involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr  X:73,506,495...73,507,638
Ensembl chr  X:73,506,495...73,507,638
JBrowse link
G Sirt1 sirtuin 1 involved_in ISO (PMID:15469825) RGD PMID:15469825 NCBI chr20:25,307,143...25,329,260
Ensembl chr20:25,306,917...25,329,260
JBrowse link
G Tnp1 transition protein 1 involved_in ISS
ISO
GO_REF:0000024
(PMID:11315969)
UniProt
RGD
PMID:11315969 GO_REF:0000024 NCBI chr 9:74,594,463...74,595,072
Ensembl chr 9:74,594,466...74,595,274
JBrowse link
G Ubr2 ubiquitin protein ligase E3 component n-recognin 2 involved_in ISO
IBA
(MGI:4431162|PMID:20080676)
PMID:21873635
RGD PMID:20080676 PMID:21873635 MGI:4431162, RGD:13792537 NCBI chr 9:13,982,427...14,062,315
Ensembl chr 9:13,982,329...14,062,139
JBrowse link
G Uty ubiquitously transcribed tetratricopeptide repeat containing, Y-linked acts_upstream_of_or_within ISO (MGI:5305502|PMID:22192413) RGD PMID:22192413 MGI:5305502 NCBI chr  Y:942,838...1,105,313
Ensembl chr  Y:924,168...1,103,422
JBrowse link
DNA methylation-dependent heterochromatin assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dnmt3a DNA methyltransferase 3 alpha acts_upstream_of_or_within ISO MGI:1261819 (MGI:3611125|PMID:16322236), (MGI:3768461|PMID:17938196) RGD PMID:16322236 PMID:17938196 MGI:3611125 MGI:3768461 NCBI chr 6:26,791,517...26,902,161
Ensembl chr 6:26,822,609...26,896,687
JBrowse link
G Dnmt3b DNA methyltransferase 3 beta acts_upstream_of_or_within ISO MGI:1261827 (MGI:3768461|PMID:17938196) RGD PMID:17938196 MGI:3768461 NCBI chr 3:142,130,592...142,169,124
Ensembl chr 3:142,130,592...142,169,124
JBrowse link
G Hdac1 histone deacetylase 1 involved_in ISO UniProtKB:Q9UBB5 (PMID:23770133) RGD PMID:23770133 NCBI chr 5:141,853,992...141,881,057
Ensembl chr 5:141,853,989...141,881,111
JBrowse link
G Hells helicase, lymphoid specific involved_in IBA
ISO
PMID:21873635
(MGI:3573964|PMID:15647320)
RGD PMID:15647320 PMID:21873635 MGI:3573964, RGD:13792537 NCBI chr 1:236,701,704...236,748,239
Ensembl chr 1:236,701,758...236,746,844
JBrowse link
G Mbd2 methyl-CpG binding domain protein 2 involved_in ISO UniProtKB:Q13547 (PMID:23770133) RGD PMID:23770133 NCBI chr18:64,174,002...64,240,795
Ensembl chr18:64,174,002...64,240,794
JBrowse link
G Mbd3 methyl-CpG binding domain protein 3 acts_upstream_of_or_within ISO (MGI:3611125|PMID:16322236) RGD PMID:16322236 MGI:3611125 NCBI chr 7:9,312,961...9,320,166
Ensembl chr 7:9,313,098...9,320,165
JBrowse link
G Smarca4 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 acts_upstream_of_or_within ISO (MGI:3611125|PMID:16322236) RGD PMID:16322236 MGI:3611125 NCBI chr 8:20,167,717...20,258,975
Ensembl chr 8:20,167,717...20,258,975
JBrowse link
heterochromatin assembly by small RNA term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fam172a family with sequence similarity 172, member A involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 2:7,553,873...8,018,183
Ensembl chr 2:7,553,891...8,018,162
JBrowse link
G Nrde2 NRDE-2, necessary for RNA interference, domain containing involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 6:119,405,103...119,446,861
Ensembl chr 6:119,404,334...119,448,915
JBrowse link
G Znfx1 zinc finger, NFX1-type containing 1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 3:155,764,073...155,791,777
Ensembl chr 3:155,764,980...155,821,242
JBrowse link
inactivation of X chromosome by heterochromatin assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Smchd1 structural maintenance of chromosomes flexible hinge domain containing 1 involved_in ISO (MGI:5532809|PMID:23754746) RGD PMID:23754746 MGI:5532809 NCBI chr 9:111,243,445...111,387,272
Ensembl chr 9:111,247,702...111,349,665
JBrowse link
negative regulation of DNA methylation-dependent heterochromatin assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aicda activation-induced cytidine deaminase involved_in ISO (PMID:21496894) RGD PMID:21496894 NCBI chr 4:155,774,132...155,783,972
Ensembl chr 4:155,774,132...155,783,972
JBrowse link
G Apobec1 apolipoprotein B mRNA editing enzyme catalytic subunit 1 involved_in ISS
ISO
GO_REF:0000024
(MGI:5285126|PMID:21496894)
UniProt
RGD
PMID:21496894 GO_REF:0000024 MGI:5285126 NCBI chr 4:155,800,030...155,828,515
Ensembl chr 4:155,800,887...155,827,390
JBrowse link
G Tet1 tet methylcytosine dioxygenase 1 involved_in ISO (PMID:21496894) RGD PMID:21496894 NCBI chr20:25,761,042...25,840,926
Ensembl chr20:25,768,120...25,833,052
JBrowse link
negative regulation of ribosomal DNA heterochromatin assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Phf2 PHD finger protein 2 involved_in ISO (PMID:20129925) RGD PMID:20129925 NCBI chr17:15,783,221...15,851,209
Ensembl chr17:15,781,864...15,851,208
JBrowse link
G Phf8 PHD finger protein 8 involved_in ISO (PMID:20208542) RGD PMID:20208542 NCBI chr  X:20,524,103...20,623,459
Ensembl chr  X:20,524,558...20,623,410
JBrowse link
positive regulation of DNA methylation-dependent heterochromatin assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atf7ip activating transcription factor 7 interacting protein involved_in ISO (PMID:27732843) RGD PMID:27732843 NCBI chr 4:169,385,872...169,471,652
Ensembl chr 4:169,385,872...169,471,650
JBrowse link
G Dnmt1 DNA methyltransferase 1 involved_in ISS
IEA
ISO
GO_REF:0000024
GO_REF:0000107
(PMID:24623306)
UniProt
Ensembl
RGD
PMID:24623306 GO_REF:0000024 GO_REF:0000107 NCBI chr 8:19,440,611...19,486,659
Ensembl chr 8:19,440,611...19,486,659
JBrowse link
G Morc2 MORC family CW-type zinc finger 2 involved_in ISO (PMID:28581500), (PMID:29211708)
(MGI:6271895|PMID:29728365)
RGD PMID:28581500 PMID:29211708 PMID:29728365 MGI:6271895 NCBI chr14:78,529,603...78,571,375
Ensembl chr14:78,527,009...78,571,343
JBrowse link
G Mphosph8 M-phase phosphoprotein 8 involved_in ISS
ISO
GO_REF:0000024
(PMID:28581500), (PMID:29211708)
UniProt
RGD
PMID:28581500 PMID:29211708 GO_REF:0000024 NCBI chr15:30,800,546...30,828,415 JBrowse link
G Pphln1 periphilin 1 involved_in ISO (PMID:28581500) RGD PMID:28581500 NCBI chr 7:124,538,594...124,629,985
Ensembl chr 7:124,538,627...124,629,985
JBrowse link
G Resf1 retroelement silencing factor 1 involved_in ISO (MGI:6271895|PMID:29728365) RGD PMID:29728365 MGI:6271895 NCBI chr 4:182,325,913...182,362,054
Ensembl chr 4:182,335,454...182,362,054
JBrowse link
G Setdb1 SET domain bifurcated histone lysine methyltransferase 1 involved_in IBA
ISO
PMID:21873635
(MGI:5440670|PMID:20164836), (MGI:6271895|PMID:29728365)
(PMID:24623306), (PMID:27732843)
RGD PMID:20164836 PMID:24623306 PMID:27732843 PMID:29728365 PMID:21873635 MGI:5440670 MGI:6271895, RGD:13792537 NCBI chr 2:182,898,738...182,930,283
Ensembl chr 2:182,898,738...182,930,506
JBrowse link
G Setdb2 SET domain bifurcated histone lysine methyltransferase 2 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr15:33,553,657...33,606,586
Ensembl chr15:33,453,952...33,606,470
JBrowse link
G Tasor transcription activation suppressor involved_in ISO
IBA
(PMID:28581500), (PMID:29211708)
PMID:21873635
RGD PMID:28581500 PMID:29211708 PMID:21873635 RGD:13792537 NCBI chr16:2,606,807...2,669,902
Ensembl chr16:2,603,936...2,667,292
JBrowse link
G Trim28 tripartite motif-containing 28 involved_in ISS
ISO
GO_REF:0000024
(MGI:5440670|PMID:20164836)
(PMID:24623306)
UniProt
RGD
PMID:20164836 PMID:24623306 GO_REF:0000024 MGI:5440670 NCBI chr 1:73,652,441...73,659,388
Ensembl chr 1:73,652,709...73,659,380
JBrowse link
positive regulation of heterochromatin assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Tpr translocated promoter region, nuclear basket protein involved_in ISO
ISS
(PMID:20407419)
GO_REF:0000024
RGD
UniProt
PMID:20407419 GO_REF:0000024 NCBI chr13:62,424,312...62,487,502
Ensembl chr13:62,424,312...62,487,496
JBrowse link
rDNA heterochromatin assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Baz2a bromodomain adjacent to zinc finger domain, 2A involved_in
acts_upstream_of_or_within
ISO (MGI:3587127|PMID:16085498), (MGI:3852313|PMID:12198165), (MGI:3852588|PMID:19578370)
(MGI:3653583|PMID:16678107), (MGI:4462332|PMID:20168299)
RGD PMID:12198165 PMID:16085498 PMID:16678107 PMID:19578370 PMID:20168299 MGI:3587127 MGI:3653583 MGI:3852313 MGI:3852588 MGI:4462332 NCBI chr 7:523,204...560,911
Ensembl chr 7:523,265...560,659
JBrowse link
G Bend3 BEN domain containing 3 involved_in ISO
IBA
(PMID:26100909)
PMID:21873635
RGD PMID:26100909 PMID:21873635 RGD:13792537 NCBI chr20:46,980,246...47,017,059
Ensembl chr20:46,979,831...47,014,671
JBrowse link
G Rrp8 ribosomal RNA processing 8 involved_in ISS
ISO
IBA
GO_REF:0000024
(PMID:18485871)
PMID:21873635
UniProt
RGD
PMID:18485871 PMID:21873635 GO_REF:0000024, RGD:13792537 NCBI chr 1:160,081,092...160,088,709
Ensembl chr 1:160,084,295...160,089,331
JBrowse link
G Sirt1 sirtuin 1 involved_in IEA
ISO
GO_REF:0000107
(PMID:18485871)
Ensembl
RGD
PMID:18485871 GO_REF:0000107 NCBI chr20:25,307,143...25,329,260
Ensembl chr20:25,306,917...25,329,260
JBrowse link
G Smarca5 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5 involved_in ISO (MGI:3587127|PMID:16085498) RGD PMID:16085498 MGI:3587127 NCBI chr19:27,271,918...27,304,594
Ensembl chr19:27,271,148...27,304,594
JBrowse link
G Suv39h1 SUV39H1 histone lysine methyltransferase involved_in ISO (PMID:18485871) RGD PMID:18485871 NCBI chr  X:141,793,695...141,795,558 JBrowse link
G Suv39h1l1 suppressor of variegation 3-9 homolog 1 (Drosophila)-like 1 involved_in IEA GO_REF:0000107 Ensembl GO_REF:0000107 NCBI chr  X:14,421,028...14,434,216
Ensembl chr  X:14,421,109...14,433,982
JBrowse link
G Ubtf upstream binding transcription factor acts_upstream_of_or_within ISO (MGI:3836497|PMID:19103806) RGD PMID:19103806 MGI:3836497 NCBI chr10:87,258,217...87,274,291
Ensembl chr10:87,258,217...87,272,969
JBrowse link
regulation of DNA methylation-dependent heterochromatin assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pou5f1 POU class 5 homeobox 1 involved_in ISO (PMID:19736317) RGD PMID:19736317 NCBI chr20:3,223,128...3,227,891
Ensembl chr20:3,223,129...3,227,891
JBrowse link
regulation of ribosomal DNA heterochromatin assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Macroh2a1 macroH2A.1 histone NOT|involved_in ISO (PMID:24071584) RGD PMID:24071584 NCBI chr17:8,479,331...8,542,071
Ensembl chr17:8,479,372...8,542,072
JBrowse link
subtelomeric heterochromatin assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dot1l DOT1 like histone lysine methyltransferase involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 7:8,917,786...8,959,474
Ensembl chr 7:8,917,786...8,956,475
JBrowse link
G Dpy30 dpy-30 histone methyltransferase complex regulatory subunit involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 6:21,120,947...21,141,720
Ensembl chr 6:21,120,947...21,141,432
JBrowse link
G Dydc1 DPY30 domain containing 1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr16:16,940,946...16,961,462
Ensembl chr16:16,939,227...16,961,460
JBrowse link
G Dydc2 DPY30 domain containing 2 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr16:16,928,172...16,941,950
Ensembl chr16:16,928,194...16,936,164
JBrowse link
G Ezh1 enhancer of zeste 1 polycomb repressive complex 2 subunit involved_in ISO UniProtKB:P38827 (MGI:892875|PMID:9214638) RGD PMID:9214638 MGI:892875 NCBI chr10:86,126,023...86,162,001
Ensembl chr10:86,126,015...86,161,921
JBrowse link
G Ezh2 enhancer of zeste 2 polycomb repressive complex 2 subunit involved_in ISO UniProtKB:P38827 (PMID:9214638) RGD PMID:9214638 NCBI chr 4:76,624,399...76,687,362
Ensembl chr 4:76,624,399...76,687,362
JBrowse link
G H3f3a H3.3 histone A acts_upstream_of_or_within ISO MGI:1101768 (MGI:5694896|PMID:26159997) RGD PMID:26159997 MGI:5694896 NCBI chr13:92,533,294...92,544,903
Ensembl chr13:92,533,298...92,544,908
JBrowse link
G H3f3b H3.3 histone B acts_upstream_of_or_within ISO MGI:1097686 (MGI:5694896|PMID:26159997) RGD PMID:26159997 MGI:5694896 NCBI chr10:101,256,488...101,258,712
Ensembl chr10:101,256,480...101,258,709
JBrowse link
G Hat1 histone acetyltransferase 1 involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 3:56,217,344...56,265,021
Ensembl chr 3:56,217,342...56,275,517
JBrowse link
G Rif1 replication timing regulatory factor 1 involved_in ISO (MGI:5584328|PMID:24735877) RGD PMID:24735877 MGI:5584328 NCBI chr 3:36,554,689...36,607,961
Ensembl chr 3:36,554,697...36,603,617
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19492
    negative regulation of biological process 5613
      negative regulation of metabolic process 3180
        negative regulation of macromolecule metabolic process 2956
          negative regulation of gene expression 1124
            gene silencing 267
              heterochromatin assembly 99
                DNA methylation-dependent heterochromatin assembly + 21
                heterochromatin assembly by small RNA + 3
                heterochromatin boundary formation 0
                heterochromatin domain assembly + 0
                heterochromatin island assembly + 0
                inactivation of X chromosome by heterochromatin assembly 1
                negative regulation of heterochromatin assembly + 5
                positive regulation of heterochromatin assembly + 11
                pre-transcriptional gene silencing by RNA + 0
                rDNA heterochromatin assembly + 11
                regulation of heterochromatin assembly + 18
                silent mating-type cassette heterochromatin assembly + 0
                subtelomeric heterochromatin assembly 10
Path 2
Term Annotations click to browse term
  biological_process 19492
    biological regulation 13513
      regulation of biological process 12769
        regulation of metabolic process 6740
          regulation of macromolecule metabolic process 6246
            negative regulation of macromolecule metabolic process 2956
              negative regulation of gene expression 1124
                negative regulation of gene expression, epigenetic 105
                  heterochromatin assembly 99
                    DNA methylation-dependent heterochromatin assembly + 21
                    heterochromatin assembly by small RNA + 3
                    heterochromatin boundary formation 0
                    heterochromatin domain assembly + 0
                    heterochromatin island assembly + 0
                    inactivation of X chromosome by heterochromatin assembly 1
                    negative regulation of heterochromatin assembly + 5
                    positive regulation of heterochromatin assembly + 11
                    pre-transcriptional gene silencing by RNA + 0
                    rDNA heterochromatin assembly + 11
                    regulation of heterochromatin assembly + 18
                    silent mating-type cassette heterochromatin assembly + 0
                    subtelomeric heterochromatin assembly 10
paths to the root