Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   

Ontology Browser

Term:
Parent Terms Term With Siblings Child Terms
gene silencing by RNA +   
heterochromatin assembly +   
An epigenetic gene silencing mechanism that involves the assembly of chromatin into heterochromatin, resulting in a chromatin conformation refractory to transcription. This process starts with heterochromatin nucleation, its spreading, and ends with heterochromatin boundary formation.
heterochromatin boundary formation 
mRNA cleavage involved in gene silencing +   
negative regulation of gene silencing +   
negative regulation of heterochromatin organization +   
pericentric heterochromatin organization +   
positive regulation of heterochromatin organization +   
posttranscriptional gene silencing +   
regulation of gene silencing +   
regulation of heterochromatin organization +   
silent mating-type cassette heterochromatin organization 

Synonyms
Exact Synonyms: chromatin silencing ;   chromatin-mediated silencing ;   establishment of heterochromatin architecture ;   heterochromatin formation ;   transcriptional gene silencing
Narrow Synonyms: establishment of heterochromatin architecture involved in chromatin silencing at centromere outer repeat region ;   establishment of heterochromatin architecture involved in chromatin silencing at pericentric region ;   heterochromatin assembly involved in chromatin silencing at centromere outer repeat region ;   heterochromatin assembly involved in chromatin silencing at pericentric region ;   heterochromatin formation involved in chromatin silencing at centromere outer repeat region ;   heterochromatin formation involved in chromatin silencing at pericentric region
Broad Synonyms: TGS ;   heterochromatin maintenance
Related Synonyms: establishment of chromatin silencing ;   establishment of heterochromatic silencing ;   heterochromatic silencing ;   heterochromatin assembly involved in chromatin silencing ;   heterochromatin formation involved in chromatin silencing
Alternate IDs: GO:0006342 ;   GO:0006343 ;   GO:0016440 ;   GO:0070869 ;   GO:1904497
Definition Sources: GOC:mah, PMID:25192661, PMID:33827924

paths to the root