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ONTOLOGY REPORT - ANNOTATIONS

Term:negative regulation of insulin-like growth factor receptor signaling pathway
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Accession:GO:0043569 term browser browse the term
Definition:Any process that stops, prevents, or reduces the frequency, rate or extent of insulin-like growth factor receptor signaling.
Synonyms:exact_synonym: down regulation of insulin-like growth factor receptor signaling pathway;   downregulation of insulin-like growth factor receptor signaling pathway;   negative regulation of IGF receptor signaling pathway;   negative regulation of IGF receptor signalling pathway;   negative regulation of insulin-like growth factor receptor signalling pathway
 narrow_synonym: inhibition of insulin-like growth factor receptor signaling pathway


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negative regulation of insulin-like growth factor receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ATXN1 ataxin 1 acts_upstream_of_or_within ISO (PMID:18216249) MGI PMID:18216249 NCBI chr 7:12,299,938...12,730,850
Ensembl chr 7:12,301,013...12,457,450 		JBrowse link
G ATXN7 ataxin 7 acts_upstream_of_or_within ISO (PMID:18216249) MGI PMID:18216249 NCBI chr13:45,356,350...45,514,816
Ensembl chr13:45,401,127...45,498,180 		JBrowse link
G BMP2 bone morphogenetic protein 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:15,750,487...15,762,982
Ensembl chr17:15,749,835...15,761,195 		JBrowse link
G BMP5 bone morphogenetic protein 5 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:25,344,924...25,468,430
Ensembl chr 7:25,344,822...25,470,470 		JBrowse link
G CILP cartilage intermediate layer protein involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:163,236,864...163,271,222
Ensembl chr 1:163,237,100...163,256,533 		JBrowse link
G FOLR2 folate receptor 2 (fetal) involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr 9:6,785,308...6,790,466
Ensembl chr 9:6,785,303...6,790,465 		JBrowse link
G IGFBP5 insulin like growth factor binding protein 5 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:16024235) Ensembl
MGI		 PMID:16024235 GO_REF:0000107 NCBI chr15:118,861,816...118,877,787
Ensembl chr15:118,857,625...118,878,120 		JBrowse link
G INPPL1 inositol polyphosphate phosphatase like 1 involved_in ISO
IBA
IEA		 RGD
GO_Central
TreeGrafter		 PMID:12933696 GO_REF:0000033 GO_REF:0000118 RGD:1626126 NCBI chr 9:6,793,971...6,807,286
Ensembl chr 9:6,793,069...6,808,028 		JBrowse link
G MIR29C microRNA mir-29c involved_in ISO (PMID:26045889), (PMID:26175848) BHF-UCL PMID:26045889 PMID:26175848 NCBI chr 9:135,019,638...135,019,725
Ensembl chr 9:135,019,638...135,019,725 		JBrowse link
G NKX3-1 NK3 homeobox 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:19258508) Ensembl
MGI		 PMID:19258508 GO_REF:0000107 NCBI chr14:7,783,296...7,787,036
Ensembl chr14:7,783,323...7,787,033 		JBrowse link
G TRIM72 tripartite motif containing 72 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:23965929) Ensembl
MGI		 PMID:23965929 GO_REF:0000107 NCBI chr 3:17,286,471...17,297,841
Ensembl chr 3:17,284,431...17,306,738 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 17806
    cellular process 16838
      signal transduction 6976
        negative regulation of signal transduction 1438
          negative regulation of insulin-like growth factor receptor signaling pathway 11
Path 2
Term Annotations click to browse term
  biological_process 17806
    biological regulation 12907
      regulation of biological process 12540
        regulation of cellular process 12047
          signal transduction 6976
            cell surface receptor signaling pathway 2809
              enzyme-linked receptor protein signaling pathway 1032
                cell surface receptor protein tyrosine kinase signaling pathway 654
                  insulin-like growth factor receptor signaling pathway 53
                    regulation of insulin-like growth factor receptor signaling pathway 28
                      negative regulation of insulin-like growth factor receptor signaling pathway 11
paths to the root