IGFBP5 (insulin like growth factor binding protein 5) - Rat Genome Database

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Gene: IGFBP5 (insulin like growth factor binding protein 5) Sus scrofa
Analyze
Symbol: IGFBP5
Name: insulin like growth factor binding protein 5
RGD ID: 13885403
Description: ENCODES a protein that exhibits fibronectin binding (ortholog); insulin-like growth factor binding (ortholog); insulin-like growth factor I binding (ortholog); INVOLVED IN aging (ortholog); cellular response to cAMP (ortholog); cellular response to organic cyclic compound (ortholog); PARTICIPATES IN insulin-like growth factor signaling pathway; ASSOCIATED WITH Breast Neoplasms (ortholog); congenital diaphragmatic hernia (ortholog); Coronary Disease (ortholog); FOUND IN insulin-like growth factor ternary complex (ortholog); INTERACTS WITH bis(2-chloroethyl) sulfide; resveratrol
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: IBP-5; IGF-binding protein 5; IGFBP-5; insulin-like growth factor-binding protein 5
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl15118,857,479 - 118,878,522 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.115118,861,816 - 118,877,787 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.215131,682,267 - 131,684,608 (-)NCBISscrofa10.2Sscrofa10.2susScr3
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:8573141   PMID:14681463   PMID:15001525   PMID:17145712   PMID:19941052   PMID:24668639  


Genomics

Comparative Map Data
IGFBP5
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl15118,857,479 - 118,878,522 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.115118,861,816 - 118,877,787 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.215131,682,267 - 131,684,608 (-)NCBISscrofa10.2Sscrofa10.2susScr3
IGFBP5
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl2216,672,105 - 216,695,549 (-)EnsemblGRCh38hg38GRCh38
GRCh382216,672,105 - 216,695,549 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh372217,536,828 - 217,560,272 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362217,245,073 - 217,268,516 (-)NCBINCBI36hg18NCBI36
Build 342217,362,334 - 217,385,777NCBI
Celera2211,304,716 - 211,328,161 (-)NCBI
Cytogenetic Map2q35NCBI
HuRef2209,391,205 - 209,414,636 (-)NCBIHuRef
CHM1_12217,543,006 - 217,566,425 (-)NCBICHM1_1
Igfbp5
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39172,897,224 - 72,914,024 (-)NCBIGRCm39mm39
GRCm39 Ensembl172,897,091 - 72,914,043 (-)Ensembl
GRCm38172,858,065 - 72,874,865 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl172,857,932 - 72,874,884 (-)EnsemblGRCm38mm10GRCm38
MGSCv37172,904,639 - 72,921,439 (-)NCBIGRCm37mm9NCBIm37
MGSCv36172,791,272 - 72,808,072 (-)NCBImm8
Celera173,426,251 - 73,443,205 (-)NCBICelera
Cytogenetic Map1C3NCBI
cM Map136.94NCBI
Igfbp5
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2974,452,371 - 74,464,953 (-)NCBI
Rnor_6.0 Ensembl980,150,211 - 80,167,033 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.0980,154,230 - 80,166,813 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0979,924,622 - 79,937,205 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4972,003,637 - 72,016,263 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1972,150,618 - 72,163,245 (-)NCBI
Celera972,045,541 - 72,058,122 (-)NCBICelera
RH 3.4 Map9679.1RGD
Cytogenetic Map9q33NCBI
Igfbp5
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495545316,530,110 - 16,550,733 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495545316,530,110 - 16,550,733 (+)NCBIChiLan1.0ChiLan1.0
IGFBP5
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.12B222,534,967 - 222,558,432 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2B222,534,967 - 222,558,432 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v02B103,932,983 - 103,956,475 (-)NCBIMhudiblu_PPA_v0panPan3
IGFBP5
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13723,575,265 - 23,596,970 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3723,579,841 - 23,596,870 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3724,403,819 - 24,425,502 (-)NCBI
ROS_Cfam_1.03723,603,056 - 23,624,922 (-)NCBI
UMICH_Zoey_3.13723,486,557 - 23,508,226 (-)NCBI
UNSW_CanFamBas_1.03723,439,644 - 23,461,314 (-)NCBI
UU_Cfam_GSD_1.03723,458,321 - 23,480,088 (-)NCBI
Igfbp5
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405303171,959,265 - 171,978,245 (-)NCBI
SpeTri2.0NW_004936586647,553 - 666,595 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
IGFBP5
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.110102,510,939 - 102,531,710 (-)NCBI
ChlSab1.1 Ensembl10102,510,897 - 102,531,724 (-)Ensembl
Vero_WHO_p1.0NW_02366604096,877,547 - 96,898,347 (+)NCBI
Igfbp5
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046248238,434,614 - 8,454,879 (+)NCBI


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system hemolymphoid system musculoskeletal system nervous system renal system reproductive system respiratory system
High
Medium 8 4 3 5 2 10 2 3 1
Low 2 13
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: NM_214099   ⟹   NP_999264
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.115118,861,816 - 118,877,787 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs NP_999264 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAA87859 (Get FASTA)   NCBI Sequence Viewer  
  ABC60328 (Get FASTA)   NCBI Sequence Viewer  
  ACD76115 (Get FASTA)   NCBI Sequence Viewer  
  ADK27481 (Get FASTA)   NCBI Sequence Viewer  
  Q28985 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: NP_999264   ⟸   NM_214099
- Peptide Label: precursor
- UniProtKB: Q28985 (UniProtKB/Swiss-Prot)
- Sequence:

Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000025924 Ensembl, ENTREZGENE
  ENSSSCG00040047315 UniProtKB/Swiss-Prot
Ensembl Protein ENSSSCP00000024248 ENTREZGENE
  ENSSSCP00040026945 UniProtKB/Swiss-Prot
Ensembl Transcript ENSSSCT00000032259 ENTREZGENE
  ENSSSCT00040063800 UniProtKB/Swiss-Prot
Gene3D-CATH 4.10.800.10 UniProtKB/Swiss-Prot
InterPro Growth_fac_rcpt_cys_sf UniProtKB/Swiss-Prot
  IGFBP-5 UniProtKB/Swiss-Prot
  IGFBP-like UniProtKB/Swiss-Prot
  IGFBP_1-6_chordata UniProtKB/Swiss-Prot
  Insulin_GF-bd_Cys-rich_CS UniProtKB/Swiss-Prot
  Thyroglobulin_1 UniProtKB/Swiss-Prot
  Thyroglobulin_1_sf UniProtKB/Swiss-Prot
KEGG Report ssc:397182 UniProtKB/Swiss-Prot
NCBI Gene IGFBP5 ENTREZGENE
PANTHER PTHR11551:SF4 UniProtKB/Swiss-Prot
Pfam IGFBP UniProtKB/Swiss-Prot
  Thyroglobulin_1 UniProtKB/Swiss-Prot
PRINTS IGFBPFAMILY UniProtKB/Swiss-Prot
  IGFBPFAMILY5 UniProtKB/Swiss-Prot
PROSITE IGFBP_N_1 UniProtKB/Swiss-Prot
  IGFBP_N_2 UniProtKB/Swiss-Prot
  THYROGLOBULIN_1_1 UniProtKB/Swiss-Prot
  THYROGLOBULIN_1_2 UniProtKB/Swiss-Prot
SMART SM00121 UniProtKB/Swiss-Prot
  SM00211 UniProtKB/Swiss-Prot
Superfamily-SCOP SSF57184 UniProtKB/Swiss-Prot
  SSF57610 UniProtKB/Swiss-Prot
UniProt B3GPL0_PIG UniProtKB/TrEMBL
  IBP5_PIG UniProtKB/Swiss-Prot, ENTREZGENE
VGNC ID VGNC:96368 ENTREZGENE