MIR29C (microRNA mir-29c) - Rat Genome Database

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Gene: MIR29C (microRNA mir-29c) Sus scrofa
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Symbol: MIR29C (Ensembl: ssc-mir-29c)
Name: microRNA mir-29c (Ensembl:ssc-mir-29c)
RGD ID: 14026391
Description: microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]
Type: ncrna (Ensembl: miRNA)
RefSeq Status: PROVISIONAL
Previously known as: microRNA 29c; ssc-mir-29c
RGD Orthologs
Human
Mouse
Dog
Alliance Orthologs
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl9135,019,638 - 135,019,725 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.19135,019,638 - 135,019,725 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.29148,552,997 - 148,553,084 (+)NCBISscrofa10.2Sscrofa10.2susScr3
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
cellular hyperosmotic salinity response  (ISO)
cellular response to amino acid stimulus  (ISO)
cellular response to ethanol  (ISO)
cellular response to leukemia inhibitory factor  (ISO)
epigenetic regulation of gene expression  (ISO)
miRNA-mediated gene silencing by inhibition of translation  (ISO)
miRNA-mediated post-transcriptional gene silencing  (IEA)
negative regulation of amyloid-beta formation  (ISO)
negative regulation of angiogenesis  (ISO)
negative regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis  (ISO)
negative regulation of canonical Wnt signaling pathway  (ISO)
negative regulation of cell cycle G1/S phase transition  (ISO)
negative regulation of cell migration  (ISO)
negative regulation of cell migration involved in sprouting angiogenesis  (ISO)
negative regulation of cell population proliferation  (ISO)
negative regulation of cell-matrix adhesion  (ISO)
negative regulation of circulating fibrinogen levels  (ISO)
negative regulation of G1/S transition of mitotic cell cycle  (ISO)
negative regulation of gene expression  (ISO)
negative regulation of insulin-like growth factor receptor signaling pathway  (ISO)
negative regulation of metalloendopeptidase activity  (ISO)
negative regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction  (ISO)
negative regulation of vascular endothelial cell proliferation  (ISO)
positive regulation of apoptotic process  (ISO)
positive regulation of mitochondrial membrane permeability involved in apoptotic process  (ISO)
tissue remodeling  (ISO)

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:15885146   PMID:16381832   PMID:20180025   PMID:21312241   PMID:24499489   PMID:33938394  


Genomics

Comparative Map Data
MIR29C
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl9135,019,638 - 135,019,725 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.19135,019,638 - 135,019,725 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.29148,552,997 - 148,553,084 (+)NCBISscrofa10.2Sscrofa10.2susScr3
MIR29C
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381207,801,852 - 207,801,939 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1207,801,852 - 207,801,939 (-)EnsemblGRCh38hg38GRCh38
GRCh371207,975,197 - 207,975,284 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361206,041,819 - 206,041,906 (-)NCBINCBI36Build 36hg18NCBI36
Celera1181,205,675 - 181,205,762 (-)NCBICelera
Cytogenetic Map1q32.2NCBI
HuRef1178,649,427 - 178,649,514 (-)NCBIHuRef
CHM1_11209,247,595 - 209,247,682 (-)NCBICHM1_1
T2T-CHM13v2.01207,048,611 - 207,048,698 (-)NCBIT2T-CHM13v2.0
Mir29c
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391194,719,855 - 194,719,942 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1194,719,855 - 194,719,942 (+)EnsemblGRCm39 Ensembl
GRCm381195,037,547 - 195,037,634 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1195,037,547 - 195,037,634 (+)EnsemblGRCm38mm10GRCm38
MGSCv371196,863,741 - 196,863,828 (+)NCBIGRCm37MGSCv37mm9NCBIm37
Celera1201,937,357 - 201,937,444 (+)NCBICelera
Cytogenetic Map1H6NCBI
cM Map198.41NCBI
MIR29C-2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.176,651,339 - 6,651,396 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha76,214,091 - 6,214,148 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.076,339,930 - 6,339,987 (-)NCBIROS_Cfam_1.0
UMICH_Zoey_3.176,272,782 - 6,272,839 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.076,375,291 - 6,375,348 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.076,416,244 - 6,416,301 (-)NCBIUU_Cfam_GSD_1.0


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
circulatory system
ectoderm
endocrine system
endoderm
hemolymphoid system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
10 4 22 3 2 5 14 12 22 3 5 3

Sequence


Ensembl Acc Id: ENSSSCT00000021258
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl9135,019,638 - 135,019,725 (+)Ensembl
RefSeq Acc Id: NR_038509
RefSeq Status: PROVISIONAL
Type: NON-CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.19135,019,638 - 135,019,725 (+)NCBI
Sequence:

Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000019663 Ensembl, ENTREZGENE
Ensembl Transcript ENSSSCT00000021258 ENTREZGENE
miRBase MI0002460 ENTREZGENE
NCBI Gene MIR29C ENTREZGENE
RNAcentral URS0000272A3D RNACentral
  URS000075B799 RNACentral


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2019-04-02 MIR29C  microRNA mir-29c    microRNA 29c  Symbol and/or name change 5135510 APPROVED