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ONTOLOGY REPORT - ANNOTATIONS

Term:xenobiotic transmembrane transporter activity
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Accession:GO:0042910 term browser browse the term
Definition:Enables the directed movement of a xenobiotic from one side of a membrane to the other. A xenobiotic is a compound foreign to the organim exposed to it. It may be synthesized by another organism (like ampicilin) or it can be a synthetic chemical.
Synonyms:related_synonym: drug transmembrane transporter activity;   drug transporter activity;   multidrug efflux pump activity;   multidrug transporter activity;   multidrug, alkane resistant pump activity;   xenobiotic transporter activity
 alt_id: GO:0015238;   GO:0015239;   GO:0015559;   GO:0015564;   GO:0090484
 xref: Reactome:R-HSA-5625574 "Defective SLC22A18 does not exchange extracellular organic cations for cytosolic H+";   Reactome:R-HSA-597628 "SLC22A18 exchanges extracellular organic cations for cytosolic H+"

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xenobiotic transmembrane transporter activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb1 ATP binding cassette subfamily B member 1 enables IEA Ensembl GO_REF:0000107 NCBI chrNW_004936763:1,225,355...1,308,257
Ensembl chrNW_004936763:1,226,482...1,297,427 		JBrowse link
G Abcc1 ATP binding cassette subfamily C member 1 (ABCC1 blood group) enables IEA Ensembl GO_REF:0000107 NCBI chrNW_004936501:3,400,971...3,467,061
Ensembl chrNW_004936501:3,401,285...3,470,460 		JBrowse link
G Abcc2 ATP binding cassette subfamily C member 2 enables IEA Ensembl GO_REF:0000107 NCBI chrNW_004936636:292,631...341,999
Ensembl chrNW_004936636:292,709...340,393 		JBrowse link
G Abcc3 ATP binding cassette subfamily C member 3 enables IEA Ensembl GO_REF:0000107 NCBI chrNW_004936490:11,039,968...11,086,670
Ensembl chrNW_004936490:11,040,445...11,086,566 		JBrowse link
G Abcc4 ATP binding cassette subfamily C member 4 (PEL blood group) enables IEA Ensembl GO_REF:0000107 NCBI chrNW_004936472:14,396,986...14,624,597
Ensembl chrNW_004936472:14,397,222...14,624,648 		JBrowse link
G Abcc5 ATP binding cassette subfamily C member 5 enables IEA Ensembl GO_REF:0000107 NCBI chrNW_004936578:5,838,044...5,916,287
Ensembl chrNW_004936578:5,837,993...5,916,274 		JBrowse link
G Atraid all-trans retinoic acid induced differentiation factor enables IEA Ensembl GO_REF:0000107 NCBI chrNW_004936493:5,333,151...5,338,157
Ensembl chrNW_004936493:5,333,169...5,338,116 		JBrowse link
G LOC101967932 multidrug and toxin extrusion protein 1 enables IEA InterPro
TreeGrafter
Ensembl		 GO_REF:0000002 GO_REF:0000107 GO_REF:0000118 NCBI chrNW_004936881:222,722...260,719
Ensembl chrNW_004936881:222,759...260,719 		JBrowse link
G LOC101970809 multidrug and toxin extrusion protein 2-like enables IEA InterPro GO_REF:0000002 NCBI chrNW_004936881:168,930...221,399 JBrowse link
G Ralbp1 ralA binding protein 1 enables IEA Ensembl GO_REF:0000107 NCBI chrNW_004936626:1,832,703...1,851,486
Ensembl chrNW_004936626:1,832,584...1,851,467 		JBrowse link
G Slc18a1 solute carrier family 18 member A1 enables IEA InterPro GO_REF:0000002 NCBI chrNW_004936555:4,249,821...4,271,379
Ensembl chrNW_004936555:4,249,821...4,271,379 		JBrowse link
G Slc18a2 solute carrier family 18 member A2 enables IEA InterPro GO_REF:0000002 NCBI chrNW_004936486:7,075,373...7,108,984
Ensembl chrNW_004936486:7,075,358...7,109,637 		JBrowse link
G Slc19a1 solute carrier family 19 member 1 enables ISO PMID:21737571 ARUK-UCL PMID:21737571 RGD:25671393 NCBI chrNW_004936778:823,376...846,843
Ensembl chrNW_004936778:829,550...848,833 		JBrowse link
G Slc22a1 solute carrier family 22 member 1 enables IEA Ensembl GO_REF:0000107 NCBI chrNW_004936489:11,534,095...11,556,759
Ensembl chrNW_004936489:11,534,095...11,556,745 		JBrowse link
G Slc22a2 solute carrier family 22 member 2 enables IEA Ensembl GO_REF:0000107 NCBI chrNW_004936489:11,605,403...11,627,786
Ensembl chrNW_004936489:11,594,480...11,627,786 		JBrowse link
G Slc22a6 solute carrier family 22 member 6 enables IEA Ensembl GO_REF:0000107 NCBI chrNW_004936581:348,719...356,246
Ensembl chrNW_004936581:349,057...356,059 		JBrowse link
G Slc22a8 solute carrier family 22 member 8 enables IEA Ensembl GO_REF:0000107 NCBI chrNW_004936581:319,372...343,171
Ensembl chrNW_004936581:319,260...343,300 		JBrowse link
G Slc29a4 solute carrier family 29 member 4 enables IEA Ensembl GO_REF:0000107 NCBI chrNW_004936765:854,712...868,001
Ensembl chrNW_004936765:855,667...864,900 		JBrowse link
G Slc2a1 solute carrier family 2 member 1 ISO RGD PMID:17064664 RGD:1624248 NCBI chrNW_004936474:24,205,878...24,236,611
Ensembl chrNW_004936474:24,206,644...24,236,713 		JBrowse link
G Slc31a1 solute carrier family 31 member 1 enables IEA Ensembl GO_REF:0000107 NCBI chrNW_004936559:333,461...364,737
Ensembl chrNW_004936559:331,917...364,852 		JBrowse link
G Slc37a3 solute carrier family 37 member 3 enables ISO (PMID:29745899)
(MGI:7444877|PMID:29745899)		 UniProt PMID:29745899 MGI:7444877 NCBI chrNW_004936592:4,453,811...4,489,343 JBrowse link
G Slc43a3 solute carrier family 43 member 3 enables ISO (PMID:30910793) UniProt PMID:30910793 NCBI chrNW_004936581:5,062,412...5,086,733 JBrowse link
ABC-type xenobiotic transporter activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abca3 ATP binding cassette subfamily A member 3 enables IEA Ensembl GO_REF:0000107 NCBI chrNW_004936694:1,735,206...1,778,100
Ensembl chrNW_004936694:1,736,207...1,778,116 		JBrowse link
G Abcb1 ATP binding cassette subfamily B member 1 enables IEA Ensembl GO_REF:0000107 NCBI chrNW_004936763:1,225,355...1,308,257
Ensembl chrNW_004936763:1,226,482...1,297,427 		JBrowse link
G Abcb11 ATP binding cassette subfamily B member 11 enables IEA Ensembl GO_REF:0000107 NCBI chrNW_004936469:10,521,576...10,599,005
Ensembl chrNW_004936469:10,521,576...10,599,005 		JBrowse link
G Abcc1 ATP binding cassette subfamily C member 1 (ABCC1 blood group) enables ISO
IEA		 estrone 3-sulfate transport RGD
TreeGrafter		 PMID:12867490 PMID:12893836 GO_REF:0000118 RGD:2303048 RGD:2303061 NCBI chrNW_004936501:3,400,971...3,467,061
Ensembl chrNW_004936501:3,401,285...3,470,460 		JBrowse link
G Abcc10 ATP binding cassette subfamily C member 10 enables IEA Ensembl GO_REF:0000107 NCBI chrNW_004936476:16,544,714...16,564,570
Ensembl chrNW_004936476:16,545,016...16,564,214 		JBrowse link
G Abcc11 ATP binding cassette subfamily C member 11 enables ISO (PMID:15537867) UniProt PMID:15537867 NCBI chrNW_004936475:1,411,996...1,473,868 JBrowse link
G Abcc2 ATP binding cassette subfamily C member 2 enables IEA Ensembl GO_REF:0000107 NCBI chrNW_004936636:292,631...341,999
Ensembl chrNW_004936636:292,709...340,393 		JBrowse link
G Abcc3 ATP binding cassette subfamily C member 3 enables IEA Ensembl GO_REF:0000107 NCBI chrNW_004936490:11,039,968...11,086,670
Ensembl chrNW_004936490:11,040,445...11,086,566 		JBrowse link
G Abcc5 ATP binding cassette subfamily C member 5 enables IEA Ensembl GO_REF:0000107 NCBI chrNW_004936578:5,838,044...5,916,287
Ensembl chrNW_004936578:5,837,993...5,916,274 		JBrowse link
G Abcc6 ATP binding cassette subfamily C member 6 enables ISO PMID:10692506 UniProt PMID:10692506 RGD:1549867 NCBI chrNW_004936501:3,469,928...3,508,577 JBrowse link
G LOC101954287 broad substrate specificity ATP-binding cassette transporter ABCG2-like enables IEA UniProt GO_REF:0000003 NCBI chrNW_004936685:405,181...461,540 JBrowse link
G LOC101954583 broad substrate specificity ATP-binding cassette transporter ABCG2 enables IEA UniProt GO_REF:0000003 NCBI chrNW_004936685:484,838...520,593 JBrowse link
G LOC101954857 broad substrate specificity ATP-binding cassette transporter ABCG2-like enables IEA UniProt GO_REF:0000003 NCBI chrNW_004936685:582,176...627,053 JBrowse link
G LOC101978435 broad substrate specificity ATP-binding cassette transporter ABCG2-like enables IEA UniProt GO_REF:0000003 NCBI chrNW_004936685:106,420...152,998 JBrowse link
methotrexate transmembrane transporter activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Slc19a1 solute carrier family 19 member 1 enables IEA InterPro
Ensembl
UniProt		 GO_REF:0000002 GO_REF:0000104 GO_REF:0000107 NCBI chrNW_004936778:823,376...846,843
Ensembl chrNW_004936778:829,550...848,833 		JBrowse link
G Slc46a1 solute carrier family 46 member 1 enables IEA Ensembl GO_REF:0000107 NCBI chrNW_004936538:4,549,032...4,642,870
Ensembl chrNW_004936538:4,549,599...4,555,415 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  molecular_function 17093
    transporter activity 1155
      transmembrane transporter activity 1066
        xenobiotic transmembrane transporter activity 32
          3-hydroxyphenylpropionic acid transmembrane transporter activity 0
          ABC-type xenobiotic transporter activity + 14
          bacteriocin transmembrane transporter activity + 0
          benzoate transmembrane transporter activity 0
          methotrexate transmembrane transporter activity 2
          microcin transmembrane transporter activity 0
paths to the root