Abcc10 (ATP binding cassette subfamily C member 10) - Rat Genome Database

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Gene: Abcc10 (ATP binding cassette subfamily C member 10) Ictidomys tridecemlineatus
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Symbol: Abcc10
Name: ATP binding cassette subfamily C member 10
RGD ID: 12543520
Description: ENCODES a protein that exhibits ABC-type glutathione S-conjugate transporter activity (inferred); ABC-type transporter activity (inferred); ABC-type xenobiotic transporter activity (inferred); INVOLVED IN leukotriene metabolic process (inferred); leukotriene transport (inferred); transmembrane transport (inferred); PARTICIPATES IN multidrug resistance-associated protein mediated transport pathway; neviparine pharmacokinetics pathway; vinblastine pharmacodynamics pathway; ASSOCIATED WITH infantile Refsum disease (ortholog); Recurrence (ortholog); Thyroid Neoplasms (ortholog); FOUND IN basal plasma membrane (inferred); basolateral plasma membrane (inferred); membrane (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: ATP-binding cassette sub-family C member 10; multidrug resistance-associated protein 7
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: SpeTri2.0 - Squirrel SpeTri2.0 Assembly
Position:
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494647,395,620 - 47,415,489 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647616,545,016 - 16,564,214 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493647616,544,714 - 16,564,570 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Abcc10
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494647,395,620 - 47,415,489 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647616,545,016 - 16,564,214 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493647616,544,714 - 16,564,570 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ABCC10
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38643,427,541 - 43,451,994 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl643,427,366 - 43,450,430 (+)EnsemblGRCh38hg38GRCh38
GRCh37643,395,279 - 43,418,165 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36643,507,467 - 43,526,141 (+)NCBINCBI36Build 36hg18NCBI36
Build 34643,507,466 - 43,526,141NCBI
Celera644,951,089 - 44,969,748 (+)NCBICelera
Cytogenetic Map6p21.1NCBI
HuRef643,113,792 - 43,136,645 (+)NCBIHuRef
CHM1_1643,398,442 - 43,421,307 (+)NCBICHM1_1
T2T-CHM13v2.0643,256,321 - 43,280,761 (+)NCBIT2T-CHM13v2.0
Abcc10
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391746,614,146 - 46,638,954 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1746,614,147 - 46,639,278 (-)EnsemblGRCm39 Ensembl
GRCm381746,303,220 - 46,328,031 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1746,303,221 - 46,328,352 (-)EnsemblGRCm38mm10GRCm38
MGSCv371746,440,179 - 46,464,972 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361745,766,762 - 45,791,226 (-)NCBIMGSCv36mm8
Celera1749,737,824 - 49,762,288 (-)NCBICelera
Cytogenetic Map17CNCBI
cM Map1722.9NCBI
Abcc10
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8922,154,811 - 22,174,743 (+)NCBIGRCr8
mRatBN7.2914,657,242 - 14,677,178 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl914,657,264 - 14,677,178 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx923,241,289 - 23,261,354 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0928,305,163 - 28,325,113 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0926,604,674 - 26,624,739 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0917,041,351 - 17,061,263 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl917,041,389 - 17,063,780 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0915,938,028 - 15,957,940 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4910,219,822 - 10,239,734 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1910,216,900 - 10,236,753 (+)NCBI
Celera912,404,578 - 12,424,492 (+)NCBICelera
Cytogenetic Map9q12NCBI
Abcc10
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554379,280,050 - 9,297,314 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554379,278,977 - 9,297,618 (+)NCBIChiLan1.0ChiLan1.0
ABCC10
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2557,927,609 - 57,950,569 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1653,797,394 - 53,820,386 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0643,019,469 - 43,042,441 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1644,311,237 - 44,333,616 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl644,311,237 - 44,333,610 (+)Ensemblpanpan1.1panPan2
ABCC10
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11211,898,493 - 11,919,622 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1211,898,352 - 11,919,609 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1211,924,582 - 11,945,736 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01212,381,910 - 12,403,092 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1212,381,939 - 12,402,758 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11211,907,401 - 11,928,528 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01211,994,460 - 12,015,635 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01212,087,766 - 12,108,890 (+)NCBIUU_Cfam_GSD_1.0
ABCC10
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl738,432,732 - 38,452,686 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1738,432,720 - 38,452,689 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2743,933,088 - 43,948,280 (+)NCBISscrofa10.2Sscrofa10.2susScr3
ABCC10
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11728,705,134 - 28,730,198 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1728,705,465 - 28,725,767 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604443,488,845 - 43,512,582 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Abcc10
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462475416,173,504 - 16,195,333 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462475416,177,849 - 16,195,753 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSSTOT00000010591   ⟹   ENSSTOP00000009506
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
SpeTri2.0 EnsemblNW_00493647616,545,016 - 16,564,214 (-)Ensembl
Ensembl Acc Id: ENSSTOT00000037529   ⟹   ENSSTOP00000030054
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
SpeTri2.0 EnsemblNW_00493647616,553,176 - 16,559,824 (-)Ensembl
RefSeq Acc Id: XM_005318645   ⟹   XP_005318702
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440494647,395,623 - 47,415,489 (+)NCBI
SpeTri2.0NW_00493647616,544,714 - 16,564,570 (-)NCBI
Sequence:
RefSeq Acc Id: XM_040282707   ⟹   XP_040138641
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440494647,395,622 - 47,415,489 (+)NCBI
RefSeq Acc Id: XM_040282708   ⟹   XP_040138642
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440494647,395,621 - 47,414,253 (+)NCBI
RefSeq Acc Id: XR_005732797
Type: NON-CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440494647,395,620 - 47,415,489 (+)NCBI
Protein Sequences
Protein RefSeqs XP_005318702 (Get FASTA)   NCBI Sequence Viewer  
  XP_040138641 (Get FASTA)   NCBI Sequence Viewer  
  XP_040138642 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSSTOP00000009506.3
  ENSSTOP00000030054.1
GenBank Protein KAG3289518 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: XP_005318702   ⟸   XM_005318645
- Peptide Label: isoform X1
- UniProtKB: I3MFS7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_040138642   ⟸   XM_040282708
- Peptide Label: isoform X3
- UniProtKB: I3MFS7 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_040138641   ⟸   XM_040282707
- Peptide Label: isoform X2
- UniProtKB: I3MFS7 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSSTOP00000009506   ⟸   ENSSTOT00000010591
Ensembl Acc Id: ENSSTOP00000030054   ⟸   ENSSTOT00000037529
Protein Domains
ABC transmembrane type-1   ABC transporter


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSTOG00000010566 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSSTOT00000010591.3 UniProtKB/TrEMBL
  ENSSTOT00000037529.1 UniProtKB/TrEMBL
Gene3D-CATH 1.20.1560.10 UniProtKB/TrEMBL
  3.40.50.300 UniProtKB/TrEMBL
InterPro AAA+_ATPase UniProtKB/TrEMBL
  ABC1_TM_dom UniProtKB/TrEMBL
  ABC1_TM_sf UniProtKB/TrEMBL
  ABC_transporter-like UniProtKB/TrEMBL
  ABC_transporter_C UniProtKB/TrEMBL
  ABC_transporter_CS UniProtKB/TrEMBL
  P-loop_NTPase UniProtKB/TrEMBL
NCBI Gene Abcc10 ENTREZGENE
PANTHER ATP-BINDING CASSETTE SUB-FAMILY C UniProtKB/TrEMBL
  ATP-BINDING CASSETTE SUB-FAMILY C MEMBER 10 UniProtKB/TrEMBL
Pfam ABC_membrane UniProtKB/TrEMBL
  ABC_tran UniProtKB/TrEMBL
PROSITE ABC_TM1F UniProtKB/TrEMBL
  ABC_TRANSPORTER_1 UniProtKB/TrEMBL
  ABC_TRANSPORTER_2 UniProtKB/TrEMBL
SMART AAA UniProtKB/TrEMBL
Superfamily-SCOP SSF52540 UniProtKB/TrEMBL
  SSF90123 UniProtKB/TrEMBL
UniProt A0A287D941_ICTTR UniProtKB/TrEMBL
  I3MFS7 ENTREZGENE, UniProtKB/TrEMBL