LOC101967932 (multidrug and toxin extrusion protein 1)

Gene: LOC101967932 (multidrug and toxin extrusion protein 1) Ictidomys tridecemlineatus

Analyze

Symbol:

LOC101967932 (Ensembl: SLC47A1)

Name:

multidrug and toxin extrusion protein 1

RGD ID:

12552622

Description:

ENCODES a protein that exhibits antiporter activity (inferred); L-amino acid transmembrane transporter activity (inferred); L-arginine transmembrane transporter activity (inferred); INVOLVED IN amino acid import across plasma membrane (inferred); L-alpha-amino acid transmembrane transport (inferred); L-arginine import across plasma membrane (inferred); FOUND IN apical plasma membrane (inferred); basolateral plasma membrane (inferred); membrane (inferred)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

multidrug and toxin extrusion protein 1, transcript variant X1; multidrug and toxin extrusion protein 1, transcript variant X2; Slc47a1; solute carrier family 47 (multidrug and toxin extrusion), member 1

Latest Assembly:

SpeTri2.0 - Squirrel SpeTri2.0 Assembly

Position:

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405602	60,326,523 - 60,364,583 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936881	222,759 - 260,719 (-)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936881	222,722 - 260,719 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

amino acid import across plasma membrane (IEA)

L-alpha-amino acid transmembrane transport (IEA)

L-arginine import across plasma membrane (IEA)

L-arginine transmembrane transport (IEA)

monoatomic cation transmembrane transport (IEA)

organic cation transport (IEA)

proton transmembrane transport (IEA)

putrescine transport (IEA)

thiamine transmembrane transport (IEA)

transmembrane transport (IEA)

xenobiotic detoxification by transmembrane export across the plasma membrane (IEA)

xenobiotic transmembrane transport (IEA)

xenobiotic transport (IEA)

Cellular Component

apical plasma membrane (IEA)

basolateral plasma membrane (IEA)

membrane (IEA)

plasma membrane (IEA)

Molecular Function

antiporter activity (IEA)

L-amino acid transmembrane transporter activity (IEA)

L-arginine transmembrane transporter activity (IEA)

organic cation transmembrane transporter activity (IEA)

polyspecific organic cation:proton antiporter activity (IEA)

putrescine transmembrane transporter activity (IEA)

thiamine transmembrane transporter activity (IEA)

xenobiotic transmembrane transporter activity (IEA)

References

Additional References at PubMed

PMID:22301074	PMID:30032202

Genomics

Expression

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_005341493	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_013365773	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_040269618	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_040269619	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_040269620	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_040269621	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_040269622	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_040269623	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	JAESOR010000662	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSSTOT00000007894 ⟹ ENSSTOP00000007065

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
SpeTri2.0 Ensembl	NW_004936881	222,759 - 260,719 (-)	Ensembl

RefSeq Acc Id:

XM_005341493 ⟹ XP_005341550

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
HiC_Itri_2	NW_024405602	60,326,523 - 60,364,583 (+)	NCBI
SpeTri2.0	NW_004936881	222,722 - 260,719 (-)	NCBI

Sequence:

show sequence

CGGCGCTCCCCGGCAGCACCGCGCAGGGCACATGGAGGCTCCCCTGGAACCCGCGCCCGGGCGG
GTAGGCCCGGAGAACACCTCGGGTCGCCGCGGGCTGCGCCGCCTGCTGTTTTCCGACTTCCGAG
AGGAGCTGCGGGCGCTCCTGATCCTGGCGGGCCCCGCGTTCTTGGCCCAGCTGATGATGTTCCT
GATCAGTTTCATAAGCTCTGTGTTTTGCGGCCATCTGGGCAAGCTGGAACTGGATGCTGTCACA
CTTGCAATTGCAGTTATCAATGTCACCGGCATTTCAGTGGGACATGGCTTATCTTCTGCATGTG
ACACCCTCATCTCCCAGACATACGGGAGCCAGAACTTGAAGTATGTGGGGGTCATCCTACAGAG
GGGCATGCTCATTCTGCTCCTCTGCTGCTTTCCCTGCTGGGCGCTTTTCCTCAACACTCAGCAC
ATCTTGCTGCTCTTCAGGCAGGACCCGGATGTGTCCAGGCTTACACAGATCTATGTGATGATCT
TCATTCCAGCTCTTCCTGCAACCTTTCTTTATATCTTACAAGTTAAATACTTGCTCAACCAGGG
AATTGTTCTGCCCCAGATCCTGACGGGAGTTGCCGCTAACCTTGTCAATGCCCTTGCCAACTAC
CTGTTTCTCCATCAACTGCATCTTGGGGTGATGGGTTCTGCATTGGCCAATATGATTGCTCAGT
TCACCCTGGCTCTCCTCCTCTTTCTCTACATCCTTGGGAGAAAACTGCATCAAGCTACATGGGG
AGGGTGGTCCCTCGAGTGCCTACAGGACTGGGCCTCCTTCCTGCGCCTGGCGATCCCAAGCATG
CTCATGCTGTGCATCGAGTGGTGGGCCTACGAGATTGGGAGCTTCCTGAGTGGTATCCTTGGCA
TGGTGGAGCTGGGAGCTCAGTCCATCGTGTATGAGCTAGCCATCATCGTGTACATGATCCCTGC
GGGCTTCAGTGTGGCTGCCAACGTCCGGGTAGGAAATGCTTTGGGTGCTGGCAACATTGAGCAA
GCAAAGAAGTCCTCTGTGGTTTCTCTGCTGGTCACAGAGCTCTTTGCTATAACATTTTGTGTCC
TGCTGTTAAGCTGTAAGGACCTCGTGGGATACATTTTCACTACTGACAGAGACATCGTTGCTCT
GGTGGCTCAGGTGGTCCCAATTTATGCTGTGTCCCACCTCTTTGAAGGACTTGCTTGTACGAGT
GGTGGCATTCTGCGGGGAACTGGAAGTCAGAAGGTGGGAGCCATTGTTAACGCCATTGGGTATT
ACGTGATTGGTCTCCCCATTGGGATCGCACTGATGTTTGCGGCCAAGCTTGGAGTGATTGGTCT
GTGGGCAGGGATCATCATCTGTACTGTCGCTCAAGCTGTGTGCTTTATAGTCTTTATTGCTCGG
CTCAACTGGAAACAAGCCTGTCAACAGGCTCAAGTACATGCCAATTTGAAGGTCAATGTGGCCC
CAGATGAGAATTCTGCTGTCCCTCAAGATCCAGTTTACCCAGTGGGTCCTGAAAACCATGGAGA
AATTTTAATGAGAGATGTTGGAAAAAAAGATGAGACTCAGTTGGACCAGCAGATGCCCCAAGAA
CAACCTTCACCTGTCCATCCAAAGAACAATGATAAATTGTCTGTGCCACAGTTGGTTCTACGGC
GAGGACTCCTGCTCGTGGGCGTCATTTTAATCTTGCTATTGGGGATTTTAGTGAGAGTATATGT
CAGAATTCAGTGATGTGCCAAGAGAGAGATGGTCAGTCAGGTCAAGGGATACAGATGTTCCTCA
ACTTACAATGGGACTACCTCCTGACAAACCCATTGTAAATTTGAAACTGTCACAAGCTGGGGCT
GGGGTTGCAGCTCAGTAATGGAACTCATGCTTAGCTTGAGGGTCTAGGTTCAATCCCCAACACC
ACATGTATGTAAGTTGACAGTGCATTGAATCCACCTATCCTACCATTCAGTGTGAGTAACACAG
CACACGGTGGCACATGATGGTGGGGCTGTGGGAGCTGCAACTTGCTGCTACAGCCCAGCATCTC
AGAGAGGATCATACTGCGTTATCTCGAACCTGGGAAAAGCTCCAAAGTACAGTTTCTACTGAAT
GTGAATCACTTTTGAAGCATCATAAATGGAACCAGTGTTAAGTCAGGGACTACCTGTACTTTTG
AGCTTACATACAAATAATTCATAGGCTTAGCAGCGGCAGTTCATTTTCAGATCCTGTAATTTAG
TTGTGACTGTGGATTTTAAGAATGGAGAATTCAAAGATATATTTTTCTAATGAAGCAGAGAGAC
TAAGAAGGTAAACGGTTTATTTTGGTTCAAGGCGATGTCTGAAAGATGATGCTTGAGAAAAATT
CACTGTCTTAACTAAGGACCATGGTGTACCATATTCACCTGACGCTTCCATGTTTCTTCTGCCC
ACTGTTTTCTAAGACACAACTCCATATAAAAAGTGCTTTAGGAT

hide sequence

RefSeq Acc Id:

XM_013365773 ⟹ XP_013221227

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
HiC_Itri_2	NW_024405602	60,326,523 - 60,364,583 (+)	NCBI
SpeTri2.0	NW_004936881	222,722 - 260,719 (-)	NCBI

Sequence:

show sequence

CGGCGCTCCCCGGCAGCACCGCGCAGGGCACATGGAGGCTCCCCTGGAACCCGCGCCCGGGCGG
GTAGGCCCGGAGAACACCTCGGGTCGCCGCGGGCTGCGCCGCCTGCTGTTTTCCGACTTCCGAG
AGGAGCTGCGGGCGCTCCTGATCCTGGCGGGCCCCGCGTTCTTGGCCCAGCTGATGATGTTCCT
GATCAGTTTCATAAGCTCTGTGTTTTGCGGCCATCTGGGCAAGCTGGAACTGGATGCTGTCACA
CTTGCAATTGCAGTTATCAATGTCACCGGCATTTCAGTGGGACATGGCTTATCTTCTGCATGTG
ACACCCTCATCTCCCAGACATACGGGAGCCAGAACTTGAAGTATGTGGGGGTCATCCTACAGAG
GGGCATGCTCATTCTGCTCCTCTGCTGCTTTCCCTGCTGGGCGCTTTTCCTCAACACTCAGCAC
ATCTTGCTGCTCTTCAGGCAGGACCCGGATGTGTCCAGGCTTACACAGATCTATGTGATGATCT
TCATTCCAGCTCTTCCTGCAACCTTTCTTTATATCTTACAAGTTAAATACTTGCTCAACCAGAA
TCTAAGTGTTCCTGCTGCCAGTCTTTCTCTGAGTCCATCCGACACCACAATGCTGATTGTATCT
TCAGACTCAAATGGAATTGTTCTGCCCCAGATCCTGACGGGAGTTGCCGCTAACCTTGTCAATG
CCCTTGCCAACTACCTGTTTCTCCATCAACTGCATCTTGGGGTGATGGGTTCTGCATTGGCCAA
TATGATTGCTCAGTTCACCCTGGCTCTCCTCCTCTTTCTCTACATCCTTGGGAGAAAACTGCAT
CAAGCTACATGGGGAGGGTGGTCCCTCGAGTGCCTACAGGACTGGGCCTCCTTCCTGCGCCTGG
CGATCCCAAGCATGCTCATGCTGTGCATCGAGTGGTGGGCCTACGAGATTGGGAGCTTCCTGAG
TGGTATCCTTGGCATGGTGGAGCTGGGAGCTCAGTCCATCGTGTATGAGCTAGCCATCATCGTG
TACATGATCCCTGCGGGCTTCAGTGTGGCTGCCAACGTCCGGGTAGGAAATGCTTTGGGTGCTG
GCAACATTGAGCAAGCAAAGAAGTCCTCTGTGGTTTCTCTGCTGGTCACAGAGCTCTTTGCTAT
AACATTTTGTGTCCTGCTGTTAAGCTGTAAGGACCTCGTGGGATACATTTTCACTACTGACAGA
GACATCGTTGCTCTGGTGGCTCAGGTGGTCCCAATTTATGCTGTGTCCCACCTCTTTGAAGGAC
TTGCTTGTACGAGTGGTGGCATTCTGCGGGGAACTGGAAGTCAGAAGGTGGGAGCCATTGTTAA
CGCCATTGGGTATTACGTGATTGGTCTCCCCATTGGGATCGCACTGATGTTTGCGGCCAAGCTT
GGAGTGATTGGTCTGTGGGCAGGGATCATCATCTGTACTGTCGCTCAAGCTGTGTGCTTTATAG
TCTTTATTGCTCGGCTCAACTGGAAACAAGCCTGTCAACAGGCTCAAGTACATGCCAATTTGAA
GGTCAATGTGGCCCCAGATGAGAATTCTGCTGTCCCTCAAGATCCAGTTTACCCAGTGGGTCCT
GAAAACCATGGAGAAATTTTAATGAGAGATGTTGGAAAAAAAGATGAGACTCAGTTGGACCAGC
AGATGCCCCAAGAACAACCTTCACCTGTCCATCCAAAGAACAATGATAAATTGTCTGTGCCACA
GTTGGTTCTACGGCGAGGACTCCTGCTCGTGGGCGTCATTTTAATCTTGCTATTGGGGATTTTA
GTGAGAGTATATGTCAGAATTCAGTGATGTGCCAAGAGAGAGATGGTCAGTCAGGTCAAGGGAT
ACAGATGTTCCTCAACTTACAATGGGACTACCTCCTGACAAACCCATTGTAAATTTGAAACTGT
CACAAGCTGGGGCTGGGGTTGCAGCTCAGTAATGGAACTCATGCTTAGCTTGAGGGTCTAGGTT
CAATCCCCAACACCACATGTATGTAAGTTGACAGTGCATTGAATCCACCTATCCTACCATTCAG
TGTGAGTAACACAGCACACGGTGGCACATGATGGTGGGGCTGTGGGAGCTGCAACTTGCTGCTA
CAGCCCAGCATCTCAGAGAGGATCATACTGCGTTATCTCGAACCTGGGAAAAGCTCCAAAGTAC
AGTTTCTACTGAATGTGAATCACTTTTGAAGCATCATAAATGGAACCAGTGTTAAGTCAGGGAC
TACCTGTACTTTTGAGCTTACATACAAATAATTCATAGGCTTAGCAGCGGCAGTTCATTTTCAG
ATCCTGTAATTTAGTTGTGACTGTGGATTTTAAGAATGGAGAATTCAAAGATATATTTTTCTAA
TGAAGCAGAGAGACTAAGAAGGTAAACGGTTTATTTTGGTTCAAGGCGATGTCTGAAAGATGAT
GCTTGAGAAAAATTCACTGTCTTAACTAAGGACCATGGTGTACCATATTCACCTGACGCTTCCA
TGTTTCTTCTGCCCACTGTTTTCTAAGACACAACTCCATATAAAAAGTGCTTTAGGAT

hide sequence

RefSeq Acc Id:

XM_040269618 ⟹ XP_040125552

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
HiC_Itri_2	NW_024405602	60,326,523 - 60,364,583 (+)	NCBI

RefSeq Acc Id:

XM_040269619 ⟹ XP_040125553

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
HiC_Itri_2	NW_024405602	60,334,727 - 60,364,583 (+)	NCBI

RefSeq Acc Id:

XM_040269620 ⟹ XP_040125554

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
HiC_Itri_2	NW_024405602	60,334,728 - 60,364,583 (+)	NCBI

RefSeq Acc Id:

XM_040269621 ⟹ XP_040125555

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
HiC_Itri_2	NW_024405602	60,326,523 - 60,364,583 (+)	NCBI

RefSeq Acc Id:

XM_040269622 ⟹ XP_040125556

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
HiC_Itri_2	NW_024405602	60,326,523 - 60,355,641 (+)	NCBI

RefSeq Acc Id:

XM_040269623 ⟹ XP_040125557

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
HiC_Itri_2	NW_024405602	60,326,523 - 60,364,583 (+)	NCBI

Protein Sequences


Protein RefSeqs	XP_005341550	(Get FASTA)	NCBI Sequence Viewer
	XP_013221227	(Get FASTA)	NCBI Sequence Viewer
	XP_040125552	(Get FASTA)	NCBI Sequence Viewer
	XP_040125553	(Get FASTA)	NCBI Sequence Viewer
	XP_040125554	(Get FASTA)	NCBI Sequence Viewer
	XP_040125555	(Get FASTA)	NCBI Sequence Viewer
	XP_040125556	(Get FASTA)	NCBI Sequence Viewer
	XP_040125557	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSSTOP00000007065.2
GenBank Protein	KAG3270284	(Get FASTA)	NCBI Sequence Viewer
	KAG3270285	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:	XP_005341550 ⟸ XM_005341493
- Peptide Label:	isoform X2
- UniProtKB:	I3MAM1 (UniProtKB/TrEMBL)
- Sequence:	show sequence MEAPLEPAPGRVGPENTSGRRGLRRLLFSDFREELRALLILAGPAFLAQLMMFLISFISSVFCG HLGKLELDAVTLAIAVINVTGISVGHGLSSACDTLISQTYGSQNLKYVGVILQRGMLILLLCCF PCWALFLNTQHILLLFRQDPDVSRLTQIYVMIFIPALPATFLYILQVKYLLNQGIVLPQILTGV AANLVNALANYLFLHQLHLGVMGSALANMIAQFTLALLLFLYILGRKLHQATWGGWSLECLQDW ASFLRLAIPSMLMLCIEWWAYEIGSFLSGILGMVELGAQSIVYELAIIVYMIPAGFSVAANVRV GNALGAGNIEQAKKSSVVSLLVTELFAITFCVLLLSCKDLVGYIFTTDRDIVALVAQVVPIYAV SHLFEGLACTSGGILRGTGSQKVGAIVNAIGYYVIGLPIGIALMFAAKLGVIGLWAGIIICTVA QAVCFIVFIARLNWKQACQQAQVHANLKVNVAPDENSAVPQDPVYPVGPENHGEILMRDVGKKD ETQLDQQMPQEQPSPVHPKNNDKLSVPQLVLRRGLLLVGVILILLLGILVRVYVRIQ hide sequence

RefSeq Acc Id:

XP_013221227 ⟸ XM_013365773

- Peptide Label:

isoform X1

- Sequence:

show sequence

MEAPLEPAPGRVGPENTSGRRGLRRLLFSDFREELRALLILAGPAFLAQLMMFLISFISSVFCG
HLGKLELDAVTLAIAVINVTGISVGHGLSSACDTLISQTYGSQNLKYVGVILQRGMLILLLCCF
PCWALFLNTQHILLLFRQDPDVSRLTQIYVMIFIPALPATFLYILQVKYLLNQNLSVPAASLSL
SPSDTTMLIVSSDSNGIVLPQILTGVAANLVNALANYLFLHQLHLGVMGSALANMIAQFTLALL
LFLYILGRKLHQATWGGWSLECLQDWASFLRLAIPSMLMLCIEWWAYEIGSFLSGILGMVELGA
QSIVYELAIIVYMIPAGFSVAANVRVGNALGAGNIEQAKKSSVVSLLVTELFAITFCVLLLSCK
DLVGYIFTTDRDIVALVAQVVPIYAVSHLFEGLACTSGGILRGTGSQKVGAIVNAIGYYVIGLP
IGIALMFAAKLGVIGLWAGIIICTVAQAVCFIVFIARLNWKQACQQAQVHANLKVNVAPDENSA
VPQDPVYPVGPENHGEILMRDVGKKDETQLDQQMPQEQPSPVHPKNNDKLSVPQLVLRRGLLLV
GVILILLLGILVRVYVRIQ

hide sequence

RefSeq Acc Id:	XP_040125555 ⟸ XM_040269621
- Peptide Label:	isoform X5

RefSeq Acc Id:	XP_040125557 ⟸ XM_040269623
- Peptide Label:	isoform X7

RefSeq Acc Id:	XP_040125552 ⟸ XM_040269618
- Peptide Label:	isoform X3

RefSeq Acc Id:	XP_040125556 ⟸ XM_040269622
- Peptide Label:	isoform X6

RefSeq Acc Id:	XP_040125553 ⟸ XM_040269619
- Peptide Label:	isoform X4

RefSeq Acc Id:	XP_040125554 ⟸ XM_040269620
- Peptide Label:	isoform X4

RefSeq Acc Id:

ENSSTOP00000007065 ⟸ ENSSTOT00000007894

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSSTOG00000007878	Ensembl, UniProtKB/TrEMBL
Ensembl Transcript	ENSSTOT00000007894.3	UniProtKB/TrEMBL
InterPro	MATE_euk	UniProtKB/TrEMBL
	MATE_fam	UniProtKB/TrEMBL
NCBI Gene	LOC101967932	ENTREZGENE
PANTHER	MULTIDRUG AND TOXIN EXTRUSION PROTEIN 1	UniProtKB/TrEMBL
	MULTIDRUG RESISTANCE PROTEIN	UniProtKB/TrEMBL
Pfam	MatE	UniProtKB/TrEMBL
UniProt	I3MAM1	ENTREZGENE, UniProtKB/TrEMBL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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