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ONTOLOGY REPORT - ANNOTATIONS

Term:xenobiotic transmembrane transporter activity
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Accession:GO:0042910 term browser browse the term
Definition:Enables the directed movement of a xenobiotic from one side of a membrane to the other. A xenobiotic is a compound foreign to the organim exposed to it. It may be synthesized by another organism (like ampicilin) or it can be a synthetic chemical.
Synonyms:related_synonym: drug transmembrane transporter activity;   drug transporter activity;   multidrug efflux pump activity;   multidrug transporter activity;   multidrug, alkane resistant pump activity;   xenobiotic transporter activity
 alt_id: GO:0015238;   GO:0015239;   GO:0015559;   GO:0015564;   GO:0090484
 xref: Reactome:R-HSA-5625574 "Defective SLC22A18 does not exchange extracellular organic cations for cytosolic H+";   Reactome:R-HSA-597628 "SLC22A18 exchanges extracellular organic cations for cytosolic H+"


show annotations for term's descendants           Sort by:
xenobiotic transmembrane transporter activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCB1 ATP binding cassette subfamily B member 1 enables IEA Ensembl GO_REF:0000107 NCBI chr 7:79,497,536...79,706,277
Ensembl chr 7:93,147,950...93,243,238 		JBrowse link
G ABCC1 ATP binding cassette subfamily C member 1 (ABCC1 blood group) enables ISO (PMID:7961706), (PMID:9281595)
(MGI:6368305|PMID:26200696)
(PMID:25986174)		 UniProt
ARUK-UCL		 PMID:7961706 PMID:9281595 PMID:25986174 PMID:26200696 MGI:6368305
G ABCC2 ATP binding cassette subfamily C member 2 enables IEA Ensembl GO_REF:0000107 NCBI chr10:96,385,534...96,458,571
Ensembl chr10:99,889,160...99,947,270 		JBrowse link
G ABCC3 ATP binding cassette subfamily C member 3 enables IEA Ensembl GO_REF:0000107 Ensembl chr17:49,603,268...49,659,318 JBrowse link
G ABCC4 ATP binding cassette subfamily C member 4 (PEL blood group) enables IEA Ensembl GO_REF:0000107 NCBI chr13:76,193,929...76,476,119
Ensembl chr13:95,349,915...95,582,058 		JBrowse link
G ABCC5 ATP binding cassette subfamily C member 5 enables IEA Ensembl GO_REF:0000107 NCBI chr 3:180,956,139...181,054,112
Ensembl chr 3:189,122,590...189,219,492 		JBrowse link
G ABCG2 ATP binding cassette subfamily G member 2 (JR blood group) enables ISO PMID:15773906 ARUK-UCL PMID:15773906 RGD:14929200 NCBI chr 4:80,379,108...80,446,641
Ensembl chr 4:91,101,321...91,170,157 		JBrowse link
G ATRAID all-trans retinoic acid induced differentiation factor enables IEA Ensembl GO_REF:0000107 NCBI chr2A:27,213,556...27,218,552
Ensembl chr2A:27,301,175...27,306,294 		JBrowse link
G CACNA1G calcium voltage-gated channel subunit alpha1 G enables IEA Ensembl GO_REF:0000107 NCBI chr17:44,654,558...44,786,037
Ensembl chr17:49,529,402...49,595,166 		JBrowse link
G RALBP1 ralA binding protein 1 enables IEA Ensembl GO_REF:0000107 NCBI chr18:4,747,555...4,810,710
Ensembl chr18:7,028,188...7,090,934 		JBrowse link
G SLC17A3 solute carrier family 17 member 3 enables ISO (PMID:20810651) UniProt PMID:20810651 NCBI chr 6:25,678,412...25,707,948 JBrowse link
G SLC18A1 solute carrier family 18 member A1 enables IEA InterPro GO_REF:0000002 NCBI chr 8:19,369,843...19,408,412
Ensembl chr 8:16,318,744...16,353,708 		JBrowse link
G SLC19A1 solute carrier family 19 member 1 enables ISO PMID:21737571 ARUK-UCL PMID:21737571 RGD:25671393 NCBI chr21:31,836,774...31,883,829
Ensembl chr21:45,090,595...45,134,752 		JBrowse link
G SLC22A1 solute carrier family 22 member 1 enables IEA Ensembl GO_REF:0000107 NCBI chr 6:158,004,545...158,046,428
Ensembl chr 6:163,014,663...163,054,681 		JBrowse link
G SLC22A2 solute carrier family 22 member 2 enables IEA Ensembl GO_REF:0000107 NCBI chr 6:158,058,226...158,150,917
Ensembl chr 6:163,065,317...163,158,931 		JBrowse link
G SLC22A6 solute carrier family 22 member 6 enables IEA Ensembl GO_REF:0000107 NCBI chr11:58,328,476...58,336,887
Ensembl chr11:61,680,016...61,688,223 		JBrowse link
G SLC22A8 solute carrier family 22 member 8 enables IEA Ensembl GO_REF:0000107 NCBI chr11:58,345,026...58,368,089
Ensembl chr11:61,696,354...61,719,413 		JBrowse link
G SLC29A4 solute carrier family 29 member 4 enables IEA Ensembl GO_REF:0000107 NCBI chr 7:5,538,436...5,559,506
Ensembl chr 7:5,560,565...5,575,637 		JBrowse link
G SLC2A1 solute carrier family 2 member 1 ISO RGD PMID:17064664 RGD:1624248 NCBI chr 1:42,224,273...42,257,184
Ensembl chr 1:43,600,733...43,634,143 		JBrowse link
G SLC31A1 solute carrier family 31 member 1 enables ISO (MGI:7434536|PMID:12370430), (MGI:7434537|PMID:19144690), (MGI:7434898|PMID:16847145) UniProt PMID:12370430 PMID:16847145 PMID:19144690 MGI:7434536 MGI:7434537 MGI:7434898 NCBI chr 9:84,319,304...84,362,288
Ensembl chr 9:112,691,503...112,734,352 		JBrowse link
G SLC37A3 solute carrier family 37 member 3 enables IEA Ensembl GO_REF:0000107 NCBI chr 7:132,236,350...132,338,150
Ensembl chr 7:144,755,561...144,815,491 		JBrowse link
G SLC43A3 solute carrier family 43 member 3 enables IEA Ensembl GO_REF:0000107 NCBI chr11:52,647,840...52,668,017
Ensembl chr 3:160,138,345...160,158,459 		JBrowse link
G SLC47A1 solute carrier family 47 member 1 enables ISO
IEA		 RGD
TreeGrafter
Ensembl
InterPro		 PMID:19004926 GO_REF:0000002 GO_REF:0000107 GO_REF:0000118 RGD:2316963 NCBI chr17:31,532,821...31,577,523
Ensembl chr17:36,695,965...36,741,618 		JBrowse link
G SLC47A2 solute carrier family 47 member 2 enables IEA InterPro GO_REF:0000002 NCBI chr17:31,412,990...31,454,667
Ensembl chr17:36,560,881...36,599,133 		JBrowse link
ABC-type xenobiotic transporter activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCA3 ATP binding cassette subfamily A member 3 enables IEA Ensembl GO_REF:0000107 NCBI chr16:1,132,435...1,196,226
Ensembl chr16:2,376,006...2,437,427 		JBrowse link
G ABCA8 ATP binding cassette subfamily A member 8 enables IEA Ensembl GO_REF:0000107 NCBI chr17:62,803,735...62,892,397
Ensembl chr17:68,192,993...68,281,666 		JBrowse link
G ABCB1 ATP binding cassette subfamily B member 1 enables IEA Ensembl GO_REF:0000107 NCBI chr 7:79,497,536...79,706,277
Ensembl chr 7:93,147,950...93,243,238 		JBrowse link
G ABCB11 ATP binding cassette subfamily B member 11 enables IEA Ensembl GO_REF:0000107 NCBI chr2B:56,199,434...56,311,773
Ensembl chr2B:173,664,518...173,776,379 		JBrowse link
G ABCC1 ATP binding cassette subfamily C member 1 (ABCC1 blood group) enables ISO
IEA		 estrone 3-sulfate transport RGD
TreeGrafter		 PMID:12867490 PMID:12893836 GO_REF:0000118 RGD:2303048 RGD:2303061
G ABCC10 ATP binding cassette subfamily C member 10 enables IEA Ensembl GO_REF:0000107 NCBI chr 6:43,019,469...43,042,441
Ensembl chr 6:44,311,237...44,333,610 		JBrowse link
G ABCC11 ATP binding cassette subfamily C member 11 enables IEA Ensembl GO_REF:0000107 NCBI chr16:28,434,749...28,513,110
Ensembl chr16:47,326,502...47,408,690 		JBrowse link
G ABCC2 ATP binding cassette subfamily C member 2 enables IEA Ensembl GO_REF:0000107 NCBI chr10:96,385,534...96,458,571
Ensembl chr10:99,889,160...99,947,270 		JBrowse link
G ABCC3 ATP binding cassette subfamily C member 3 enables IEA Ensembl GO_REF:0000107 Ensembl chr17:49,603,268...49,659,318 JBrowse link
G ABCC5 ATP binding cassette subfamily C member 5 enables IEA Ensembl GO_REF:0000107 NCBI chr 3:180,956,139...181,054,112
Ensembl chr 3:189,122,590...189,219,492 		JBrowse link
G ABCG2 ATP binding cassette subfamily G member 2 (JR blood group) enables IEA Ensembl
UniProt		 GO_REF:0000003 GO_REF:0000107 NCBI chr 4:80,379,108...80,446,641
Ensembl chr 4:91,101,321...91,170,157 		JBrowse link
G CACNA1G calcium voltage-gated channel subunit alpha1 G enables IEA Ensembl GO_REF:0000107 NCBI chr17:44,654,558...44,786,037
Ensembl chr17:49,529,402...49,595,166 		JBrowse link
methotrexate transmembrane transporter activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G SLC19A1 solute carrier family 19 member 1 enables IEA UniProt
Ensembl
InterPro		 GO_REF:0000002 GO_REF:0000104 GO_REF:0000107 NCBI chr21:31,836,774...31,883,829
Ensembl chr21:45,090,595...45,134,752 		JBrowse link
G SLC46A1 solute carrier family 46 member 1 enables IEA Ensembl GO_REF:0000107 NCBI chr17:28,367,674...28,379,618
Ensembl chr17:28,870,678...28,877,632 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  molecular_function 17493
    transporter activity 1158
      transmembrane transporter activity 1070
        xenobiotic transmembrane transporter activity 30
          3-hydroxyphenylpropionic acid transmembrane transporter activity 0
          ABC-type xenobiotic transporter activity + 12
          bacteriocin transmembrane transporter activity + 0
          benzoate transmembrane transporter activity 0
          methotrexate transmembrane transporter activity 2
          microcin transmembrane transporter activity 0
paths to the root