SLC47A1 (solute carrier family 47 member 1) - Rat Genome Database

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Gene: SLC47A1 (solute carrier family 47 member 1) Pan paniscus
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Symbol: SLC47A1
Name: solute carrier family 47 member 1
RGD ID: 11890627
Description: ENCODES a protein that exhibits amide transmembrane transporter activity (ortholog); xenobiotic transmembrane transporter activity (ortholog); INVOLVED IN monoatomic cation transmembrane transport (ortholog); monoatomic cation transport (ortholog); organic cation transport (ortholog); PARTICIPATES IN cisplatin response pathway; metformin pharmacokinetics pathway; ASSOCIATED WITH autistic disorder (ortholog); common variable immunodeficiency 2 (ortholog); genetic disease (ortholog); FOUND IN vesicle (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: LOC100968979; multidrug and toxin extrusion protein 1
RGD Orthologs
Human
Mouse
Rat
Dog
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21954,546,053 - 54,590,827 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11759,357,895 - 59,403,316 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01731,532,821 - 31,577,523 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11736,697,753 - 36,741,618 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1736,695,965 - 36,741,618 (-)Ensemblpanpan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
SLC47A1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21954,546,053 - 54,590,827 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11759,357,895 - 59,403,316 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01731,532,821 - 31,577,523 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11736,697,753 - 36,741,618 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1736,695,965 - 36,741,618 (-)Ensemblpanpan1.1panPan2
SLC47A1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381719,533,854 - 19,579,034 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1719,495,385 - 19,579,034 (+)EnsemblGRCh38hg38GRCh38
GRCh371719,437,167 - 19,482,347 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361719,377,759 - 19,422,938 (+)NCBINCBI36Build 36hg18NCBI36
Celera1716,849,963 - 16,895,249 (+)NCBICelera
Cytogenetic Map17p11.2NCBI
HuRef1718,816,528 - 18,861,586 (+)NCBIHuRef
CHM1_11719,446,156 - 19,491,334 (+)NCBICHM1_1
T2T-CHM13v2.01719,482,011 - 19,527,180 (+)NCBIT2T-CHM13v2.0
Slc47a1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391161,234,226 - 61,269,668 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1161,234,227 - 61,269,171 (-)EnsemblGRCm39 Ensembl
GRCm381161,343,400 - 61,378,842 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1161,343,401 - 61,378,345 (-)EnsemblGRCm38mm10GRCm38
MGSCv371161,156,902 - 61,191,577 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361161,159,595 - 61,194,259 (-)NCBIMGSCv36mm8
MGSCv361161,773,092 - 61,807,757 (-)NCBIMGSCv36mm8
Cytogenetic Map11B2NCBI
cM Map1137.96NCBI
Slc47a1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81046,533,580 - 46,590,128 (-)NCBIGRCr8
mRatBN7.21046,034,115 - 46,088,617 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1046,034,122 - 46,087,637 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1050,738,327 - 50,772,534 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01050,228,852 - 50,263,054 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01045,732,272 - 45,766,477 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01047,631,425 - 47,685,379 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1047,632,192 - 47,666,921 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01047,405,592 - 47,440,116 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41047,514,258 - 47,548,353 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11047,526,815 - 47,561,996 (-)NCBI
Celera1045,287,837 - 45,321,882 (-)NCBICelera
Cytogenetic Map10q22NCBI
SLC47A1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1540,643,420 - 40,679,130 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl540,642,784 - 40,679,946 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha540,784,775 - 40,821,055 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0540,751,334 - 40,787,406 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl540,750,862 - 40,788,216 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1540,719,937 - 40,756,209 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0540,666,150 - 40,702,838 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0540,858,535 - 40,895,055 (-)NCBIUU_Cfam_GSD_1.0
SLC47A1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1260,021,188 - 60,056,938 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11260,021,176 - 60,114,488 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
SLC47A1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11618,124,681 - 18,168,702 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1618,125,252 - 18,169,552 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660592,677,293 - 2,726,316 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Slc47a1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248495,776,180 - 5,830,871 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248495,775,925 - 5,831,941 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


RefSeq Acc Id: ENSPPAT00000064744   ⟹   ENSPPAP00000041818
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl1736,695,965 - 36,741,618 (-)Ensembl
RefSeq Acc Id: ENSPPAT00000064747   ⟹   ENSPPAP00000041821
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl1736,695,965 - 36,741,618 (-)Ensembl
RefSeq Acc Id: ENSPPAT00000064753   ⟹   ENSPPAP00000041827
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl1736,698,673 - 36,741,522 (-)Ensembl
RefSeq Acc Id: ENSPPAT00000064754   ⟹   ENSPPAP00000041828
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl1736,699,233 - 36,741,522 (-)Ensembl
RefSeq Acc Id: ENSPPAT00000064755   ⟹   ENSPPAP00000041829
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl1736,699,233 - 36,727,732 (-)Ensembl
RefSeq Acc Id: ENSPPAT00000064757   ⟹   ENSPPAP00000041831
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl1736,699,450 - 36,741,522 (-)Ensembl
RefSeq Acc Id: XM_003807275   ⟹   XP_003807323
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21954,546,053 - 54,590,827 (+)NCBI
NHGRI_mPanPan11759,357,895 - 59,403,314 (+)NCBI
Mhudiblu_PPA_v01731,532,821 - 31,577,523 (-)NCBI
PanPan1.11736,697,753 - 36,741,618 (-)NCBI
Sequence:
RefSeq Acc Id: XM_008959366   ⟹   XP_008957614
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21954,546,053 - 54,590,827 (+)NCBI
NHGRI_mPanPan11759,357,895 - 59,403,316 (+)NCBI
Mhudiblu_PPA_v01731,532,821 - 31,577,523 (-)NCBI
PanPan1.11736,697,753 - 36,741,618 (-)NCBI
Sequence:
RefSeq Acc Id: XM_008959367   ⟹   XP_008957615
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21954,546,053 - 54,590,827 (+)NCBI
NHGRI_mPanPan11759,357,895 - 59,403,315 (+)NCBI
Mhudiblu_PPA_v01731,534,386 - 31,577,523 (-)NCBI
PanPan1.11736,699,224 - 36,741,618 (-)NCBI
Sequence:
RefSeq Acc Id: XM_063599226   ⟹   XP_063455296
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21954,546,053 - 54,584,577 (+)NCBI
RefSeq Acc Id: XP_008957614   ⟸   XM_008959366
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_003807323   ⟸   XM_003807275
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_008957615   ⟸   XM_008959367
- Peptide Label: isoform X3
- Sequence:
RefSeq Acc Id: ENSPPAP00000041831   ⟸   ENSPPAT00000064757
RefSeq Acc Id: ENSPPAP00000041829   ⟸   ENSPPAT00000064755
RefSeq Acc Id: ENSPPAP00000041827   ⟸   ENSPPAT00000064753
RefSeq Acc Id: ENSPPAP00000041828   ⟸   ENSPPAT00000064754
RefSeq Acc Id: ENSPPAP00000041821   ⟸   ENSPPAT00000064747
RefSeq Acc Id: ENSPPAP00000041818   ⟸   ENSPPAT00000064744
RefSeq Acc Id: XP_063455296   ⟸   XM_063599226
- Peptide Label: isoform X4


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000043503 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000064744.1 UniProtKB/TrEMBL
  ENSPPAT00000064747.1 UniProtKB/TrEMBL
  ENSPPAT00000064753.1 UniProtKB/TrEMBL
  ENSPPAT00000064754.1 UniProtKB/TrEMBL
  ENSPPAT00000064755.1 UniProtKB/TrEMBL
  ENSPPAT00000064757.1 UniProtKB/TrEMBL
InterPro MATE_euk UniProtKB/TrEMBL
  MATE_fam UniProtKB/TrEMBL
KEGG Report pps:100968979 UniProtKB/TrEMBL
NCBI Gene SLC47A1 ENTREZGENE
PANTHER MULTIDRUG AND TOXIN EXTRUSION PROTEIN 1 UniProtKB/TrEMBL
  MULTIDRUG RESISTANCE PROTEIN UniProtKB/TrEMBL
Pfam MatE UniProtKB/TrEMBL
UniProt A0A2R9CIM8_PANPA UniProtKB/TrEMBL
  A0A2R9CIP1_PANPA UniProtKB/TrEMBL
  A0A2R9CIQ6_PANPA UniProtKB/TrEMBL
  A0A2R9CLD6_PANPA UniProtKB/TrEMBL
  A0A2R9CLE6_PANPA UniProtKB/TrEMBL
  A0A2R9CRX8_PANPA UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2020-07-01 SLC47A1  solute carrier family 47 member 1  LOC100968979  multidrug and toxin extrusion protein 1  Symbol and/or name change 5135510 APPROVED
2018-05-08 LOC100968979  multidrug and toxin extrusion protein 1  SLC47A1  solute carrier family 47 member 1  Symbol and/or name change 5135510 APPROVED