SLC47A1 (solute carrier family 47 member 1) - Rat Genome Database

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Gene: SLC47A1 (solute carrier family 47 member 1) Pan paniscus
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Symbol: SLC47A1
Name: solute carrier family 47 member 1
RGD ID: 11890627
Description: ENCODES a protein that exhibits amide transmembrane transporter activity (ortholog); xenobiotic transmembrane transporter activity (ortholog); INVOLVED IN monoatomic cation transmembrane transport (ortholog); monoatomic cation transport (ortholog); organic cation transport (ortholog); PARTICIPATES IN cisplatin response pathway; metformin pharmacokinetics pathway; ASSOCIATED WITH autistic disorder (ortholog); common variable immunodeficiency 2 (ortholog); Joubert syndrome 1 (ortholog); FOUND IN vesicle (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: LOC100968979; multidrug and toxin extrusion protein 1
RGD Orthologs
Human
Mouse
Rat
Dog
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21954,546,053 - 54,590,827 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11759,357,895 - 59,403,316 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01731,532,821 - 31,577,523 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11736,697,753 - 36,741,618 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1736,695,965 - 36,741,618 (-)Ensemblpanpan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
SLC47A1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21954,546,053 - 54,590,827 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11759,357,895 - 59,403,316 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01731,532,821 - 31,577,523 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11736,697,753 - 36,741,618 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1736,695,965 - 36,741,618 (-)Ensemblpanpan1.1panPan2
SLC47A1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381719,533,854 - 19,579,034 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1719,495,385 - 19,579,034 (+)EnsemblGRCh38hg38GRCh38
GRCh371719,437,167 - 19,482,347 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361719,377,759 - 19,422,938 (+)NCBINCBI36Build 36hg18NCBI36
Celera1716,849,963 - 16,895,249 (+)NCBICelera
Cytogenetic Map17p11.2NCBI
HuRef1718,816,528 - 18,861,586 (+)NCBIHuRef
CHM1_11719,446,156 - 19,491,334 (+)NCBICHM1_1
T2T-CHM13v2.01719,482,011 - 19,527,180 (+)NCBIT2T-CHM13v2.0
Slc47a1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391161,234,226 - 61,269,668 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1161,234,227 - 61,269,171 (-)EnsemblGRCm39 Ensembl
GRCm381161,343,400 - 61,378,842 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1161,343,401 - 61,378,345 (-)EnsemblGRCm38mm10GRCm38
MGSCv371161,156,902 - 61,191,577 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361161,159,595 - 61,194,259 (-)NCBIMGSCv36mm8
MGSCv361161,773,092 - 61,807,757 (-)NCBIMGSCv36mm8
Cytogenetic Map11B2NCBI
cM Map1137.96NCBI
Slc47a1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81046,533,580 - 46,590,128 (-)NCBIGRCr8
mRatBN7.21046,034,115 - 46,088,617 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1046,034,122 - 46,087,637 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1050,738,327 - 50,772,534 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01050,228,852 - 50,263,054 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01045,732,272 - 45,766,477 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01047,631,425 - 47,685,379 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1047,632,192 - 47,666,921 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01047,405,592 - 47,440,116 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41047,514,258 - 47,548,353 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11047,526,815 - 47,561,996 (-)NCBI
Celera1045,287,837 - 45,321,882 (-)NCBICelera
Cytogenetic Map10q22NCBI
SLC47A1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1540,643,420 - 40,679,130 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl540,642,784 - 40,679,946 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha540,784,775 - 40,821,055 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0540,751,334 - 40,787,406 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl540,750,862 - 40,788,216 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1540,719,937 - 40,756,209 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0540,666,150 - 40,702,838 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0540,858,535 - 40,895,055 (-)NCBIUU_Cfam_GSD_1.0
SLC47A1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1260,021,188 - 60,056,938 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11260,021,176 - 60,114,488 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
SLC47A1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11618,124,681 - 18,168,702 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1618,125,252 - 18,169,552 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660592,677,293 - 2,726,316 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Slc47a1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248495,776,180 - 5,830,871 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248495,775,925 - 5,831,941 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSPPAT00000064744   ⟹   ENSPPAP00000041818
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl1736,695,965 - 36,741,618 (-)Ensembl
Ensembl Acc Id: ENSPPAT00000064747   ⟹   ENSPPAP00000041821
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl1736,695,965 - 36,741,618 (-)Ensembl
Ensembl Acc Id: ENSPPAT00000064753   ⟹   ENSPPAP00000041827
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl1736,698,673 - 36,741,522 (-)Ensembl
Ensembl Acc Id: ENSPPAT00000064754   ⟹   ENSPPAP00000041828
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl1736,699,233 - 36,741,522 (-)Ensembl
Ensembl Acc Id: ENSPPAT00000064755   ⟹   ENSPPAP00000041829
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl1736,699,233 - 36,727,732 (-)Ensembl
Ensembl Acc Id: ENSPPAT00000064757   ⟹   ENSPPAP00000041831
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl1736,699,450 - 36,741,522 (-)Ensembl
RefSeq Acc Id: XM_003807275   ⟹   XP_003807323
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21954,546,053 - 54,590,827 (+)NCBI
NHGRI_mPanPan11759,357,895 - 59,403,314 (+)NCBI
Mhudiblu_PPA_v01731,532,821 - 31,577,523 (-)NCBI
PanPan1.11736,697,753 - 36,741,618 (-)NCBI
Sequence:
RefSeq Acc Id: XM_008959366   ⟹   XP_008957614
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21954,546,053 - 54,590,827 (+)NCBI
NHGRI_mPanPan11759,357,895 - 59,403,316 (+)NCBI
Mhudiblu_PPA_v01731,532,821 - 31,577,523 (-)NCBI
PanPan1.11736,697,753 - 36,741,618 (-)NCBI
Sequence:
RefSeq Acc Id: XM_008959367   ⟹   XP_008957615
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21954,546,053 - 54,590,827 (+)NCBI
NHGRI_mPanPan11759,357,895 - 59,403,315 (+)NCBI
Mhudiblu_PPA_v01731,534,386 - 31,577,523 (-)NCBI
PanPan1.11736,699,224 - 36,741,618 (-)NCBI
Sequence:
RefSeq Acc Id: XM_063599226   ⟹   XP_063455296
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21954,546,053 - 54,584,577 (+)NCBI
RefSeq Acc Id: XP_008957614   ⟸   XM_008959366
- Peptide Label: isoform X2
- UniProtKB: A0A2R9CIM8 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_003807323   ⟸   XM_003807275
- Peptide Label: isoform X1
- UniProtKB: A0A2R9CLD6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_008957615   ⟸   XM_008959367
- Peptide Label: isoform X3
- UniProtKB: A0A2R9CIP1 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSPPAP00000041831   ⟸   ENSPPAT00000064757
Ensembl Acc Id: ENSPPAP00000041829   ⟸   ENSPPAT00000064755
Ensembl Acc Id: ENSPPAP00000041827   ⟸   ENSPPAT00000064753
Ensembl Acc Id: ENSPPAP00000041828   ⟸   ENSPPAT00000064754
Ensembl Acc Id: ENSPPAP00000041821   ⟸   ENSPPAT00000064747
Ensembl Acc Id: ENSPPAP00000041818   ⟸   ENSPPAT00000064744
RefSeq Acc Id: XP_063455296   ⟸   XM_063599226
- Peptide Label: isoform X4
- UniProtKB: A0A2R9CIP1 (UniProtKB/TrEMBL)


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000043503 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000064744.1 UniProtKB/TrEMBL
  ENSPPAT00000064747.1 UniProtKB/TrEMBL
  ENSPPAT00000064753.1 UniProtKB/TrEMBL
  ENSPPAT00000064754.1 UniProtKB/TrEMBL
  ENSPPAT00000064755.1 UniProtKB/TrEMBL
  ENSPPAT00000064757.1 UniProtKB/TrEMBL
InterPro MATE_euk UniProtKB/TrEMBL
  MATE_fam UniProtKB/TrEMBL
KEGG Report pps:100968979 UniProtKB/TrEMBL
NCBI Gene SLC47A1 ENTREZGENE
PANTHER MULTIDRUG RESISTANCE PROTEIN UniProtKB/TrEMBL
Pfam MatE UniProtKB/TrEMBL
UniProt A0A2R9CIM8 ENTREZGENE, UniProtKB/TrEMBL
  A0A2R9CIP1 ENTREZGENE, UniProtKB/TrEMBL
  A0A2R9CIQ6_PANPA UniProtKB/TrEMBL
  A0A2R9CLD6 ENTREZGENE, UniProtKB/TrEMBL
  A0A2R9CLE6_PANPA UniProtKB/TrEMBL
  A0A2R9CRX8_PANPA UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2020-07-01 SLC47A1  solute carrier family 47 member 1  LOC100968979  multidrug and toxin extrusion protein 1  Symbol and/or name change 5135510 APPROVED
2018-05-08 LOC100968979  multidrug and toxin extrusion protein 1  SLC47A1  solute carrier family 47 member 1  Symbol and/or name change 5135510 APPROVED