Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models   new Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources

ONTOLOGY REPORT - ANNOTATIONS

Term:Rb-E2F complex
go back to main search page
Accession:GO:0035189 term browser browse the term
Definition:A multiprotein complex containing a heterodimeric E2F transcription factor and a Retinoblastoma (Rb) family member. This complex is capable of repressing transcription of E2F-regulated genes in order to regulate cell cycle progression.
Synonyms:exact_synonym: retinoblastoma-E2F complex


show annotations for term's descendants           Sort by:
Rb-E2F complex term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CEBPA CCAAT enhancer binding protein alpha ISO RGD PMID:16172914 RGD:1625368 NCBI chr19:33,299,934...33,302,534
Ensembl chr19:33,299,934...33,302,534 		JBrowse link
G E2F1 E2F transcription factor 1 located_in
part_of		 IPI
IBA
IDA		 (PMID:16360038)
(PMID:20224733)		 ComplexPortal
GO_Central
BHF-UCL		 PMID:16360038 PMID:20224733 GO_REF:0000033 NCBI chr20:33,675,477...33,686,385
Ensembl chr20:33,675,477...33,686,385 		JBrowse link
G E2F2 E2F transcription factor 2 located_in ISS ComplexPortal GO_REF:0000114 NCBI chr 1:23,505,212...23,531,233
Ensembl chr 1:23,506,438...23,531,233 		JBrowse link
G RB1 RB transcriptional corepressor 1 part_of
located_in		 TAS
IBA
IEA
ISS
IDA
IPI		 (PMID:19149898)
(PMID:8245034)
(PMID:16360038)		 BHF-UCL
GO_Central
TreeGrafter
ComplexPortal
Ensembl
CAFA		 PMID:8245034 PMID:16360038 PMID:19149898 GO_REF:0000033 GO_REF:0000107 GO_REF:0000114 GO_REF:0000118 NCBI chr13:48,303,751...48,481,890
Ensembl chr13:48,303,744...48,599,436 		JBrowse link
G TFDP1 transcription factor Dp-1 located_in IPI
ISS		 (PMID:16360038) ComplexPortal PMID:16360038 GO_REF:0000114 NCBI chr13:113,584,688...113,641,473
Ensembl chr13:113,584,721...113,641,473 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  cellular_component 20811
    protein-containing complex 7477
      transcription regulator complex 593
        RNA polymerase II transcription regulator complex 297
          Rb-E2F complex 5
Path 2
Term Annotations click to browse term
  cellular_component 20811
    cellular anatomical entity 20424
      intracellular anatomical structure 16295
        intracellular organelle 14632
          intracellular membrane-bounded organelle 13442
            nucleus 8683
              nuclear protein-containing complex 1432
                RNA polymerase II transcription regulator complex 297
                  Rb-E2F complex 5
paths to the root