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ONTOLOGY REPORT - ANNOTATIONS

Term:B-1a B cell differentiation
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Accession:GO:0002337 term browser browse the term
Definition:The process in which B cells acquire the specialized features of B-1a B cells. B-1a B cells are B-1 cells that express CD5 and arise from fetal liver precursors.
Comment:Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.
Synonyms:exact_synonym: B-1a B lymphocyte differentiation
 related_synonym: B-1a B cell development


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B-1a B cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CMTM7 CKLF like MARVEL transmembrane domain containing 7 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:24080084) Ensembl
MGI		 PMID:24080084 GO_REF:0000107 NCBI chr 3:32,391,853...32,455,528
Ensembl chr 3:32,391,698...32,483,067 		JBrowse link
G DPP4 dipeptidyl peptidase 4 ISO RGD PMID:19327106 RGD:41408336 NCBI chr 2:161,992,245...162,074,215
Ensembl chr 2:161,992,245...162,074,394 		JBrowse link
G NFATC1 nuclear factor of activated T cells 1 acts_upstream_of_or_within ISO (PMID:14595020) MGI PMID:14595020 NCBI chr18:79,395,930...79,529,323
Ensembl chr18:79,395,856...79,529,325 		JBrowse link
G PLCL2 phospholipase C like 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:14517301) Ensembl
MGI		 PMID:14517301 GO_REF:0000107 NCBI chr 3:16,884,955...17,090,606
Ensembl chr 3:16,802,651...17,090,604 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19670
    immune system process 3226
      leukocyte activation 1138
        lymphocyte activation 932
          lymphocyte differentiation 513
            B cell differentiation 193
              mature B cell differentiation 45
                B-1 B cell differentiation 7
                  B-1a B cell differentiation 4
Path 2
Term Annotations click to browse term
  biological_process 19670
    developmental process 7619
      cellular developmental process 5185
        cell differentiation 5184
          cell development 3453
            hemopoiesis 1167
              leukocyte differentiation 749
                mononuclear cell differentiation 620
                  lymphocyte differentiation 513
                    B cell differentiation 193
                      mature B cell differentiation 45
                        B-1 B cell differentiation 7
                          B-1a B cell differentiation 4
paths to the root