Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   

ONTOLOGY REPORT - ANNOTATIONS


Term:B-1 B cell differentiation
go back to main search page
Accession:GO:0001923 term browser browse the term
Definition:The process in which a hemopoietic stem cell acquires the specialized features of a B-1 B cell. B-1 B cells are a distinct subset of B cells characterized as being CD5 positive, found predominantly in the peritoneum, pleural cavities, and spleen, and enriched for self-reactivity.
Synonyms:exact_synonym: B-1 B-lymphocyte differentiation
 related_synonym: B-1 B cell development



show annotations for term's descendants           Sort by:
B-1 B cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd19 CD19 molecule involved_in ISO (PMID:7543183) RGD PMID:7543183 NCBI chr 1:190,417,853...190,424,494 JBrowse link
G Malt1 MALT1 paracaspase acts_upstream_of_or_within ISO MGI:3639305 (PMID:14614861) RGD PMID:14614861 NCBI chr18:61,212,290...61,266,272 JBrowse link
B-1 B cell lineage commitment term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Slamf8 SLAM family member 8 involved_in ISO (PMID:11313408) RGD PMID:11313408 NCBI chr13:85,047,729...85,057,571 JBrowse link
B-1a B cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cmtm7 CKLF-like MARVEL transmembrane domain containing 7 acts_upstream_of_or_within ISO (PMID:24080084) RGD PMID:24080084 NCBI chr 8:114,448,037...114,474,958 JBrowse link
G Dpp4 dipeptidylpeptidase 4 IMP RGD PMID:19327106 RGD:41408336 NCBI chr 3:67,370,794...67,452,422 JBrowse link
G Nfatc1 nuclear factor of activated T-cells 1 acts_upstream_of_or_within ISO MGI:2181762 (PMID:14595020) RGD PMID:14595020 NCBI chr18:76,321,386...76,430,997 JBrowse link
G Plcl2 phospholipase C-like 2 acts_upstream_of_or_within ISO MGI:2679632 (PMID:14517301) RGD PMID:14517301 NCBI chr 9:3,292,564...3,477,009 JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20534
    immune system process 3112
      leukocyte activation 1070
        lymphocyte activation 867
          lymphocyte differentiation 446
            B cell differentiation 154
              mature B cell differentiation 43
                B-1 B cell differentiation 7
                  B-1 B cell lineage commitment 1
                  B-1a B cell differentiation 4
                  B-1b B cell differentiation 0
                  negative regulation of B-1 B cell differentiation 0
                  positive regulation of B-1 B cell differentiation 0
                  regulation of B-1 B cell differentiation + 0
Path 2
Term Annotations click to browse term
  biological_process 20534
    developmental process 7107
      cellular developmental process 4811
        cell differentiation 4810
          cell development 3338
            hemopoiesis 1078
              leukocyte differentiation 685
                mononuclear cell differentiation 549
                  lymphocyte differentiation 446
                    B cell differentiation 154
                      mature B cell differentiation 43
                        B-1 B cell differentiation 7
                          B-1 B cell lineage commitment 1
                          B-1a B cell differentiation 4
                          B-1b B cell differentiation 0
                          negative regulation of B-1 B cell differentiation 0
                          positive regulation of B-1 B cell differentiation 0
                          regulation of B-1 B cell differentiation + 0
paths to the root