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Term:
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B-1 B cell differentiation +   
The process in which a hemopoietic stem cell acquires the specialized features of a B-1 B cell. B-1 B cells are a distinct subset of B cells characterized as being CD5 positive, found predominantly in the peritoneum, pleural cavities, and spleen, and enriched for self-reactivity.
mature B cell differentiation involved in immune response +   

Synonyms
Exact Synonyms: B-1 B-lymphocyte differentiation
Related Synonyms: B-1 B cell development
Definition Sources: GOC:add, ISBN:0781735149

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