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ONTOLOGY REPORT - ANNOTATIONS


Term:positive regulation of mitophagy
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Accession:GO:1901526 term browser browse the term
Definition:Any process that activates or increases the frequency, rate or extent of mitophagy.
Synonyms:exact_synonym: positive regulation of macromitophagy;   up-regulation of macromitophagy;   upregulation of macromitophagy
 narrow_synonym: activation of macromitophagy



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positive regulation of mitophagy term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AMBRA1 autophagy and beclin 1 regulator 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr18:42,903,815...43,073,918
Ensembl chr18:42,932,513...43,072,827
JBrowse link
G ATG7 autophagy related 7 ISO RGD PMID:37042059 RGD:407532700 NCBI chr20:6,916,354...7,154,849
Ensembl chr20:6,916,515...7,154,800
JBrowse link
G CERS1 ceramide synthase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr20:44,216,568...44,231,820 JBrowse link
G DELE1 DAP3 binding cell death enhancer 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:36,865,275...36,880,304
Ensembl chr 2:36,865,289...36,879,840
JBrowse link
G EIF2AK1 eukaryotic translation initiation factor 2 alpha kinase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:11,447,225...11,478,611
Ensembl chr 6:11,447,081...11,478,658
JBrowse link
G FBXO7 F-box protein 7 involved_in IEA Ensembl GO_REF:0000107 NCBI chr10:30,928,059...30,948,858
Ensembl chr10:30,928,329...30,948,977
JBrowse link
G GRK4 G protein-coupled receptor kinase 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:61,233,066...61,331,094
Ensembl chr 3:61,079,904...61,330,290
JBrowse link
G HIF1A hypoxia inducible factor 1 subunit alpha involved_in IEA Ensembl GO_REF:0000107 NCBI chr 8:36,614,045...36,656,692
Ensembl chr 8:36,614,045...36,656,692
JBrowse link
G HTT huntingtin involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:61,076,934...61,221,462
Ensembl chr 3:61,079,904...61,330,290
JBrowse link
G LOC481473 immunity-related GTPase family M protein involved_in ISO (PMID:21102437), (PMID:32939830) UniProt PMID:21102437 PMID:32939830 NCBI chr11:793,416...795,373
Ensembl chr11:793,424...794,617
JBrowse link
G LOC606863 immunity-related GTPase family M protein-like involved_in ISO (PMID:33510463) UniProt PMID:33510463 NCBI chr11:506,981...523,338
Ensembl chr11:509,636...510,829
JBrowse link
G NOD2 nucleotide binding oligomerization domain containing 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:64,636,850...64,667,232
Ensembl chr 2:64,635,519...64,667,232
JBrowse link
G PRKN parkin RBR E3 ubiquitin protein ligase involved_in ISO
IEA
RGD
Ensembl
PMID:28608965 GO_REF:0000107 RGD:13432560 NCBI chr 1:49,886,887...51,201,930
Ensembl chr 1:49,889,005...51,201,764
JBrowse link
G SLC25A4 solute carrier family 25 member 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr16:45,454,660...45,458,606
Ensembl chr16:45,411,810...45,542,162
JBrowse link
G SLC25A5 solute carrier family 25 member 5 involved_in ISO (PMID:31618756) UniProt PMID:31618756 NCBI chr  X:91,523,649...91,526,447
Ensembl chr  X:91,523,643...91,526,479
JBrowse link
G STUB1 STIP1 homology and U-box containing protein 1 involved_in ISO PMID:29934347 UniProt PMID:29934347 RGD:405650300 NCBI chr 6:39,893,492...39,895,385
Ensembl chr 6:39,893,670...39,897,573
JBrowse link
G UBE2A ubiquitin conjugating enzyme E2 A involved_in ISO (PMID:23685073) UniProt PMID:23685073 NCBI chr  X:91,608,936...91,617,993
Ensembl chr  X:91,529,855...91,617,086
JBrowse link
G VPS13D vacuolar protein sorting 13 homolog D involved_in ISO (PMID:29307555) UniProt PMID:29307555 NCBI chr 2:83,898,620...84,132,453
Ensembl chr 2:83,901,018...84,132,529
JBrowse link
positive regulation of type 2 mitophagy term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ATP5IF1 ATP synthase inhibitory factor subunit 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:72,188,562...72,191,344
Ensembl chr 2:72,188,266...72,191,326
JBrowse link
G CDC37 cell division cycle 37, HSP90 cochaperone involved_in IEA Ensembl GO_REF:0000107 NCBI chr20:50,727,702...50,738,197
Ensembl chr20:50,727,749...50,736,269
JBrowse link
G GBA1 glucosylceramidase beta 1 acts_upstream_of_or_within
involved_in
ISO
IEA
(PMID:23707074) ARUK-UCL
Ensembl
PMID:23707074 GO_REF:0000107 NCBI chr 7:42,317,704...42,322,285
Ensembl chr 7:42,317,862...42,322,864
JBrowse link
G HDAC6 histone deacetylase 6 involved_in IEA Ensembl GO_REF:0000107 NCBI chr  X:42,004,268...42,024,726
Ensembl chr  X:42,004,591...42,024,427
JBrowse link
G HK2 hexokinase 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:48,287,367...48,329,470
Ensembl chr17:48,289,272...48,348,663
JBrowse link
G HUWE1 HECT, UBA and WWE domain containing E3 ubiquitin protein ligase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr  X:45,234,666...45,409,641
Ensembl chr  X:45,234,322...45,410,043
JBrowse link
G MUL1 mitochondrial E3 ubiquitin protein ligase 1 involved_in ISO (PMID:24709290) ParkinsonsUK-UCL PMID:24709290 NCBI chr 2:78,394,013...78,402,032
Ensembl chr 2:78,394,040...78,425,482
JBrowse link
G PINK1 PTEN induced kinase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:78,276,091...78,293,761
Ensembl chr 2:78,277,077...78,294,123
JBrowse link
G PRKN parkin RBR E3 ubiquitin protein ligase involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:49,886,887...51,201,930
Ensembl chr 1:49,889,005...51,201,764
JBrowse link
G TOMM7 translocase of outer mitochondrial membrane 7 involved_in ISO (PMID:24270810) ParkinsonsUK-UCL PMID:24270810 NCBI chr14:36,523,707...36,532,180
Ensembl chr14:36,523,707...36,532,291
JBrowse link
G VDAC1 voltage dependent anion channel 1 involved_in ISO (PMID:32047033) UniProt PMID:32047033 NCBI chr11:22,197,814...22,212,924
Ensembl chr11:22,197,949...22,212,924
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 17101
    cellular process 16595
      process utilizing autophagic mechanism 505
        autophagy 505
          positive regulation of autophagy 164
            positive regulation of autophagy of mitochondrion 29
              positive regulation of mitophagy 28
                positive regulation of type 2 mitophagy 11
Path 2
Term Annotations click to browse term
  biological_process 17101
    biological regulation 11805
      regulation of biological process 11454
        regulation of cellular process 11121
          regulation of metabolic process 6206
            positive regulation of metabolic process 3735
              positive regulation of catabolic process 613
                positive regulation of autophagy 164
                  positive regulation of macroautophagy 100
                    positive regulation of mitophagy 28
                      positive regulation of type 2 mitophagy 11
paths to the root