STUB1 (STIP1 homology and U-box containing protein 1) - Rat Genome Database

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Gene: STUB1 (STIP1 homology and U-box containing protein 1) Canis lupus familiaris
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Symbol: STUB1
Name: STIP1 homology and U-box containing protein 1
RGD ID: 12325293
Description: ENCODES a protein that exhibits enzyme binding (inferred); G protein-coupled receptor binding (inferred); heat shock protein binding (inferred); INVOLVED IN MAPK cascade (ortholog); negative regulation of apoptotic process (ortholog); negative regulation of cardiac muscle hypertrophy (ortholog); ASSOCIATED WITH autosomal recessive spinocerebellar ataxia 16 (ortholog); cerebellar ataxia type 48 (ortholog); epilepsy (ortholog); FOUND IN mitochondrion (ortholog); nucleus (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: E3 ubiquitin-protein ligase CHIP
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1639,893,492 - 39,895,385 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl639,893,670 - 39,897,573 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha641,157,620 - 41,160,024 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0640,236,147 - 40,238,551 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl640,236,151 - 40,238,584 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1639,924,709 - 39,927,112 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0639,884,918 - 39,887,322 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0640,364,058 - 40,366,462 (-)NCBIUU_Cfam_GSD_1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

References
Additional References at PubMed
PMID:26156079   PMID:30032202  


Genomics

Comparative Map Data
STUB1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1639,893,492 - 39,895,385 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl639,893,670 - 39,897,573 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha641,157,620 - 41,160,024 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0640,236,147 - 40,238,551 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl640,236,151 - 40,238,584 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1639,924,709 - 39,927,112 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0639,884,918 - 39,887,322 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0640,364,058 - 40,366,462 (-)NCBIUU_Cfam_GSD_1.0
STUB1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3816680,410 - 682,801 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl16680,224 - 682,870 (+)EnsemblGRCh38hg38GRCh38
GRCh3716730,410 - 732,801 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 3616670,116 - 672,769 (+)NCBINCBI36Build 36hg18NCBI36
Build 3416670,115 - 672,768NCBI
Celera16930,272 - 932,925 (+)NCBICelera
Cytogenetic Map16p13.3NCBI
HuRef16651,974 - 654,645 (+)NCBIHuRef
CHM1_116730,089 - 732,742 (+)NCBICHM1_1
T2T-CHM13v2.016684,485 - 686,876 (+)NCBIT2T-CHM13v2.0
Stub1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391726,049,608 - 26,051,893 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1726,049,479 - 26,052,378 (-)EnsemblGRCm39 Ensembl
GRCm381725,830,634 - 25,832,919 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1725,830,505 - 25,833,404 (-)EnsemblGRCm38mm10GRCm38
MGSCv371725,967,581 - 25,970,306 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361725,558,236 - 25,560,961 (-)NCBIMGSCv36mm8
Celera1726,363,459 - 26,366,184 (-)NCBICelera
Cytogenetic Map17A3.3NCBI
cM Map1712.93NCBI
Stub1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81015,355,278 - 15,357,559 (-)NCBIGRCr8
mRatBN7.21014,850,765 - 14,853,046 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1014,850,765 - 14,853,046 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1019,589,774 - 19,592,055 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01019,078,650 - 19,080,931 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01014,578,930 - 14,581,211 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01015,197,754 - 15,200,035 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1015,197,803 - 15,200,117 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01015,010,697 - 15,012,978 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41015,096,150 - 15,098,431 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11015,096,147 - 15,098,378 (-)NCBI
Celera1014,519,707 - 14,521,988 (-)NCBICelera
Cytogenetic Map10q12NCBI
Stub1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495544216,521,130 - 16,523,468 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495544216,521,130 - 16,523,733 (-)NCBIChiLan1.0ChiLan1.0
STUB1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v218921,269 - 923,958 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1164,705,136 - 4,707,825 (+)NCBINHGRI_mPanPan1
PanPan1.116694,414 - 696,682 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl16694,414 - 696,682 (+)Ensemblpanpan1.1panPan2
Stub1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024409344112,230,907 - 112,233,127 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936501326,451 - 330,983 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936501328,767 - 330,963 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
STUB1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl341,092,449 - 41,095,136 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1341,092,514 - 41,095,181 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2341,382,439 - 41,385,101 (+)NCBISscrofa10.2Sscrofa10.2susScr3
STUB1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.15599,907 - 602,549 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl5599,819 - 605,567 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366606830,534,608 - 30,537,266 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Stub1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046249131,491,991 - 1,494,249 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046249131,491,873 - 1,494,249 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in STUB1
4 total Variants

Sequence


Ensembl Acc Id: ENSCAFT00000049790   ⟹   ENSCAFP00000036229
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl639,893,670 - 39,897,573 (-)Ensembl
Ensembl Acc Id: ENSCAFT00845047539   ⟹   ENSCAFP00845037301
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl640,236,151 - 40,238,584 (-)Ensembl
RefSeq Acc Id: XM_038479624   ⟹   XP_038335552
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.1639,924,709 - 39,927,112 (-)NCBI
RefSeq Acc Id: XM_038540905   ⟹   XP_038396833
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.0640,364,058 - 40,366,462 (-)NCBI
RefSeq Acc Id: XM_038551199   ⟹   XP_038407127
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
Dog10K_Boxer_Tasha641,157,620 - 41,160,024 (-)NCBI
RefSeq Acc Id: XM_038605030   ⟹   XP_038460958
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.0639,884,918 - 39,887,322 (-)NCBI
RefSeq Acc Id: XM_038669705   ⟹   XP_038525633
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0640,236,147 - 40,238,551 (-)NCBI
Ensembl Acc Id: ENSCAFP00000036229   ⟸   ENSCAFT00000049790
RefSeq Acc Id: XP_038335552   ⟸   XM_038479624
RefSeq Acc Id: XP_038460958   ⟸   XM_038605030
RefSeq Acc Id: XP_038525633   ⟸   XM_038669705
- UniProtKB: A0A8C0N702 (UniProtKB/TrEMBL),   A0A8C0K769 (UniProtKB/TrEMBL),   A0A8I3PT83 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038407127   ⟸   XM_038551199
- UniProtKB: A0A8C0N702 (UniProtKB/TrEMBL),   A0A8C0K769 (UniProtKB/TrEMBL),   A0A8I3PT83 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038396833   ⟸   XM_038540905
- UniProtKB: A0A8C0K769 (UniProtKB/TrEMBL),   A0A8C0N702 (UniProtKB/TrEMBL),   A0A8I3PT83 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSCAFP00845037301   ⟸   ENSCAFT00845047539
Protein Domains
U-box


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000031099 Ensembl, UniProtKB/TrEMBL
  ENSCAFG00030012499 UniProtKB/TrEMBL
  ENSCAFG00040003540 UniProtKB/TrEMBL
  ENSCAFG00845026980 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCAFT00000049790.3 UniProtKB/TrEMBL
  ENSCAFT00030023169.1 UniProtKB/TrEMBL
  ENSCAFT00040006733.1 UniProtKB/TrEMBL
  ENSCAFT00845047539 ENTREZGENE
  ENSCAFT00845047539.1 UniProtKB/TrEMBL
Gene3D-CATH 1.25.40.10 UniProtKB/TrEMBL
  3.30.40.10 UniProtKB/TrEMBL
  6.10.140.2020 UniProtKB/TrEMBL
InterPro CHIP/LubX_RING-Ubox UniProtKB/TrEMBL
  CHIP_TPR_N UniProtKB/TrEMBL
  TPR-like_helical_dom_sf UniProtKB/TrEMBL
  TPR_repeat UniProtKB/TrEMBL
  Ubox_domain UniProtKB/TrEMBL
  Znf_RING/FYVE/PHD UniProtKB/TrEMBL
NCBI Gene STUB1 ENTREZGENE
PANTHER E3 UBIQUITIN-PROTEIN LIGASE CHIP UniProtKB/TrEMBL
  PTHR46803 UniProtKB/TrEMBL
Pfam ANAPC3 UniProtKB/TrEMBL
  CHIP_TPR_N UniProtKB/TrEMBL
  U-box UniProtKB/TrEMBL
PROSITE TPR UniProtKB/TrEMBL
  U_BOX UniProtKB/TrEMBL
SMART TPR UniProtKB/TrEMBL
  Ubox UniProtKB/TrEMBL
Superfamily-SCOP RING/U-box UniProtKB/TrEMBL
  SSF48452 UniProtKB/TrEMBL
UniProt A0A8C0K769 ENTREZGENE
  A0A8C0N702 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I3PT83 ENTREZGENE, UniProtKB/TrEMBL
VGNC ID VGNC:54073 ENTREZGENE