HDAC6 (histone deacetylase 6) - Rat Genome Database

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Gene: HDAC6 (histone deacetylase 6) Canis lupus familiaris
Analyze
Symbol: HDAC6
Name: histone deacetylase 6
RGD ID: 12417654
Description: ENCODES a protein that exhibits acetylspermidine deacetylase activity (ortholog); deacetylase activity (ortholog); misfolded protein binding (ortholog); INVOLVED IN actin filament organization (ortholog); aggresome assembly (ortholog); axonal transport of mitochondrion (ortholog); PARTICIPATES IN histone modification pathway; ASSOCIATED WITH autistic disorder (ortholog); cervix uteri carcinoma in situ (ortholog); cholangiocarcinoma (ortholog); FOUND IN axon (ortholog); centrosome (ortholog)
Type: protein-coding
RefSeq Status: MODEL
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1X42,004,268 - 42,024,726 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 EnsemblX42,004,591 - 42,024,427 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_TashaX16,379,688 - 16,400,160 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0X42,140,437 - 42,160,915 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 EnsemblX42,140,480 - 42,160,909 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1X42,126,695 - 42,147,162 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0X42,114,965 - 42,135,438 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0X42,209,124 - 42,229,594 (+)NCBIUU_Cfam_GSD_1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
actin filament organization  (IEA,ISO)
aggresome assembly  (IEA,ISO)
axonal transport of mitochondrion  (IEA,ISO)
cellular response to hydrogen peroxide  (IEA)
cellular response to misfolded protein  (IEA,ISO)
cellular response to parathyroid hormone stimulus  (ISO)
cellular response to topologically incorrect protein  (IEA)
cilium disassembly  (IEA)
collateral sprouting  (IEA,ISO)
dendritic spine morphogenesis  (IEA,ISO)
erythrocyte enucleation  (IEA,ISO)
Hsp90 deacetylation  (ISO)
intracellular protein transport  (IEA)
lysosome localization  (IEA)
mitochondrion localization  (IEA)
negative regulation of aggrephagy  (IEA)
negative regulation of axon extension involved in axon guidance  (ISO)
negative regulation of gene expression, epigenetic  (IEA)
negative regulation of microtubule depolymerization  (IEA,ISO)
negative regulation of neuron projection development  (ISO)
negative regulation of protein acetylation  (ISO)
negative regulation of protein-containing complex assembly  (IEA)
negative regulation of protein-containing complex disassembly  (IEA)
negative regulation of proteolysis  (IEA)
neuron differentiation  (ISO)
peptidyl-lysine deacetylation  (ISO)
polyamine deacetylation  (ISO)
polyubiquitinated misfolded protein transport  (IEA)
positive regulation of cellular response to oxidative stress  (ISO)
positive regulation of cholangiocyte proliferation  (ISO)
positive regulation of dendrite morphogenesis  (ISO)
positive regulation of epithelial cell migration  (IEA)
positive regulation of peptidyl-serine phosphorylation  (ISO)
positive regulation of signaling receptor activity  (ISO)
positive regulation of synaptic transmission, glutamatergic  (ISO)
positive regulation of tubulin deacetylation  (ISO)
positive regulation of type 2 mitophagy  (IEA)
protein deacetylation  (ISO)
protein deacylation  (ISO)
protein destabilization  (IEA)
protein polyubiquitination  (IEA,ISO)
protein quality control for misfolded or incompletely synthesized proteins  (IEA)
protein-containing complex disassembly  (IEA,ISO)
regulation of establishment of protein localization  (IEA,ISO)
regulation of fat cell differentiation  (IEA,ISO)
regulation of macroautophagy  (IEA)
regulation of microtubule cytoskeleton organization  (ISO)
regulation of mitochondrion organization  (ISO)
regulation of protein phosphorylation  (ISO)
regulation of protein stability  (IEA)
response to amphetamine  (ISO)
response to corticosterone  (ISO)
response to dexamethasone  (ISO)
response to growth factor  (IEA)
response to immobilization stress  (ISO)
response to misfolded protein  (IEA)
spermidine deacetylation  (ISO)
tubulin deacetylation  (ISO)
type 2 mitophagy  (IEA)
ubiquitin-dependent protein catabolic process  (IEA,ISO)
ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway  (IEA,ISO)

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:22301074   PMID:24146251   PMID:25031336   PMID:30032202  


Genomics

Comparative Map Data
HDAC6
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1X42,004,268 - 42,024,726 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 EnsemblX42,004,591 - 42,024,427 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_TashaX16,379,688 - 16,400,160 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0X42,140,437 - 42,160,915 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 EnsemblX42,140,480 - 42,160,909 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1X42,126,695 - 42,147,162 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0X42,114,965 - 42,135,438 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0X42,209,124 - 42,229,594 (+)NCBIUU_Cfam_GSD_1.0
HDAC6
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38X48,801,398 - 48,824,982 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 EnsemblX48,801,377 - 48,824,982 (+)EnsemblGRCh38hg38GRCh38
GRCh37X48,659,805 - 48,683,392 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36X48,545,431 - 48,568,324 (+)NCBINCBI36Build 36hg18NCBI36
Build 34X48,416,735 - 48,439,629NCBI
CeleraX52,980,148 - 53,003,041 (-)NCBICelera
Cytogenetic MapXp11.23NCBI
HuRefX46,319,662 - 46,343,018 (+)NCBIHuRef
CHM1_1X48,691,631 - 48,714,524 (+)NCBICHM1_1
T2T-CHM13v2.0X48,211,870 - 48,235,478 (+)NCBIT2T-CHM13v2.0
Hdac6
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39X7,796,355 - 7,814,284 (-)NCBIGRCm39GRCm39mm39
GRCm39 EnsemblX7,796,359 - 7,814,128 (-)EnsemblGRCm39 Ensembl
GRCm38X7,930,116 - 7,948,047 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 EnsemblX7,930,120 - 7,947,889 (-)EnsemblGRCm38mm10GRCm38
MGSCv37X7,507,248 - 7,525,015 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36X7,087,085 - 7,104,203 (-)NCBIMGSCv36mm8
CeleraX3,521,555 - 3,539,209 (+)NCBICelera
Cytogenetic MapXA1.1NCBI
cM MapX3.58NCBI
Hdac6
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8X17,222,538 - 17,244,373 (+)NCBIGRCr8
mRatBN7.2X14,550,645 - 14,572,445 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 EnsemblX14,551,044 - 14,572,441 (+)EnsemblmRatBN7.2 Ensembl
Rnor_6.0X15,396,185 - 15,417,486 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 EnsemblX15,295,473 - 15,316,671 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.0 EnsemblX15,396,895 - 15,417,146 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0X16,075,029 - 16,096,914 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4X26,585,852 - 26,606,999 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1X26,658,892 - 26,659,565 (+)NCBI
CeleraX14,635,909 - 14,657,201 (+)NCBICelera
Cytogenetic MapXq12NCBI
Hdac6
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955543348,019 - 378,071 (+)EnsemblChiLan1.0
ChiLan1.0NW_004955543348,314 - 378,391 (+)NCBIChiLan1.0ChiLan1.0
HDAC6
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2X50,290,594 - 50,314,118 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1X50,293,976 - 50,317,490 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0X41,099,539 - 41,122,650 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1X48,960,181 - 48,982,648 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 EnsemblX48,960,430 - 48,982,642 (+)Ensemblpanpan1.1panPan2
Hdac6
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2X34,517,114 - 34,538,029 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936721758,181 - 778,053 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936721757,500 - 778,416 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
HDAC6
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 EnsemblX42,917,964 - 42,941,887 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1X42,917,911 - 42,941,894 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2X47,858,997 - 47,883,202 (+)NCBISscrofa10.2Sscrofa10.2susScr3
HDAC6
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1X45,927,625 - 45,951,636 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 EnsemblX45,928,092 - 45,952,929 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366607611,407,911 - 11,431,438 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Hdac6
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624893608,540 - 628,580 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_004624893608,744 - 627,600 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in HDAC6
113 total Variants

Expression

RNA-SEQ Expression

adipose tissue
alimentary part of gastrointestinal system
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
reproductive system
respiratory system
6 5 5 23 22 16 6 6 6 6 33 22 12 14 10

Sequence

Nucleotide Sequences
RefSeq Transcripts XM_005641325 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_005641326 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_005641327 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_005641328 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_005641329 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_014111656 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_022415720 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_022415721 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_022415722 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_022415723 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_022415724 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038449950 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038449951 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038449952 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038449953 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038449955 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038449956 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038523399 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038523400 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038523402 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038523403 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038523404 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038523405 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038587369 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038587370 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038587371 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038587372 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038587373 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038587374 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038651882 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038651883 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038651884 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038651885 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038651886 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038651887 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AAEX04000146 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAAHUQ010000372 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAAQRD010000110 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAAUVH010000175 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  REHQ01000039 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSCAFT00000024781   ⟹   ENSCAFP00000022990
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 EnsemblX42,004,709 - 42,024,427 (+)Ensembl
Ensembl Acc Id: ENSCAFT00000061245   ⟹   ENSCAFP00000049288
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 EnsemblX42,004,591 - 42,024,193 (+)Ensembl
Ensembl Acc Id: ENSCAFT00000066433   ⟹   ENSCAFP00000057585
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 EnsemblX42,004,709 - 42,024,193 (+)Ensembl
Ensembl Acc Id: ENSCAFT00000084286   ⟹   ENSCAFP00000053674
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 EnsemblX42,004,709 - 42,024,193 (+)Ensembl
Ensembl Acc Id: ENSCAFT00000088614   ⟹   ENSCAFP00000057790
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 EnsemblX42,004,709 - 42,024,193 (+)Ensembl
Ensembl Acc Id: ENSCAFT00000092977   ⟹   ENSCAFP00000053562
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 EnsemblX42,004,709 - 42,024,427 (+)Ensembl
Ensembl Acc Id: ENSCAFT00845054969   ⟹   ENSCAFP00845043222
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 EnsemblX42,140,480 - 42,160,901 (+)Ensembl
Ensembl Acc Id: ENSCAFT00845054976   ⟹   ENSCAFP00845043227
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 EnsemblX42,140,769 - 42,160,909 (+)Ensembl
RefSeq Acc Id: XM_005641325   ⟹   XP_005641382
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1X42,004,919 - 42,024,726 (+)NCBI
Dog10K_Boxer_TashaX16,380,362 - 16,400,160 (+)NCBI
Sequence:
RefSeq Acc Id: XM_005641326   ⟹   XP_005641383
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1X42,004,268 - 42,024,726 (+)NCBI
Dog10K_Boxer_TashaX16,379,688 - 16,400,160 (+)NCBI
Sequence:
RefSeq Acc Id: XM_005641327   ⟹   XP_005641384
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1X42,004,858 - 42,024,726 (+)NCBI
Dog10K_Boxer_TashaX16,380,287 - 16,400,160 (+)NCBI
Sequence:
RefSeq Acc Id: XM_005641328   ⟹   XP_005641385
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1X42,004,574 - 42,024,726 (+)NCBI
Dog10K_Boxer_TashaX16,380,003 - 16,400,160 (+)NCBI
Sequence:
RefSeq Acc Id: XM_014111656   ⟹   XP_013967131
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1X42,004,575 - 42,024,726 (+)NCBI
Dog10K_Boxer_TashaX16,380,004 - 16,400,160 (+)NCBI
Sequence:
RefSeq Acc Id: XM_022415720   ⟹   XP_022271428
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1X42,004,573 - 42,024,726 (+)NCBI
Dog10K_Boxer_TashaX16,380,002 - 16,400,160 (+)NCBI
Sequence:
RefSeq Acc Id: XM_038449950   ⟹   XP_038305878
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0X42,140,752 - 42,160,915 (+)NCBI
RefSeq Acc Id: XM_038449951   ⟹   XP_038305879
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0X42,140,751 - 42,160,915 (+)NCBI
RefSeq Acc Id: XM_038449952   ⟹   XP_038305880
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0X42,140,753 - 42,160,915 (+)NCBI
RefSeq Acc Id: XM_038449953   ⟹   XP_038305881
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0X42,141,111 - 42,160,915 (+)NCBI
RefSeq Acc Id: XM_038449955   ⟹   XP_038305883
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0X42,140,437 - 42,160,915 (+)NCBI
RefSeq Acc Id: XM_038449956   ⟹   XP_038305884
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0X42,141,036 - 42,160,915 (+)NCBI
RefSeq Acc Id: XM_038523399   ⟹   XP_038379327
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.1X42,127,010 - 42,147,162 (+)NCBI
RefSeq Acc Id: XM_038523400   ⟹   XP_038379328
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.1X42,127,009 - 42,147,162 (+)NCBI
RefSeq Acc Id: XM_038523402   ⟹   XP_038379330
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.1X42,127,011 - 42,147,162 (+)NCBI
RefSeq Acc Id: XM_038523403   ⟹   XP_038379331
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.1X42,127,369 - 42,147,162 (+)NCBI
RefSeq Acc Id: XM_038523404   ⟹   XP_038379332
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.1X42,126,695 - 42,147,162 (+)NCBI
RefSeq Acc Id: XM_038523405   ⟹   XP_038379333
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.1X42,127,294 - 42,147,162 (+)NCBI
RefSeq Acc Id: XM_038587369   ⟹   XP_038443297
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.0X42,209,439 - 42,229,594 (+)NCBI
RefSeq Acc Id: XM_038587370   ⟹   XP_038443298
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.0X42,209,438 - 42,229,594 (+)NCBI
RefSeq Acc Id: XM_038587371   ⟹   XP_038443299
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.0X42,209,440 - 42,229,594 (+)NCBI
RefSeq Acc Id: XM_038587372   ⟹   XP_038443300
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.0X42,209,798 - 42,229,594 (+)NCBI
RefSeq Acc Id: XM_038587373   ⟹   XP_038443301
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.0X42,209,124 - 42,229,594 (+)NCBI
RefSeq Acc Id: XM_038587374   ⟹   XP_038443302
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.0X42,209,723 - 42,229,594 (+)NCBI
RefSeq Acc Id: XM_038651882   ⟹   XP_038507810
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.0X42,115,280 - 42,135,438 (+)NCBI
RefSeq Acc Id: XM_038651883   ⟹   XP_038507811
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.0X42,115,279 - 42,135,438 (+)NCBI
RefSeq Acc Id: XM_038651884   ⟹   XP_038507812
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.0X42,115,281 - 42,135,438 (+)NCBI
RefSeq Acc Id: XM_038651885   ⟹   XP_038507813
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.0X42,115,639 - 42,135,438 (+)NCBI
RefSeq Acc Id: XM_038651886   ⟹   XP_038507814
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.0X42,114,965 - 42,135,438 (+)NCBI
RefSeq Acc Id: XM_038651887   ⟹   XP_038507815
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.0X42,115,564 - 42,135,438 (+)NCBI
Protein Sequences
Protein RefSeqs XP_005641382 (Get FASTA)   NCBI Sequence Viewer  
  XP_005641383 (Get FASTA)   NCBI Sequence Viewer  
  XP_005641384 (Get FASTA)   NCBI Sequence Viewer  
  XP_005641385 (Get FASTA)   NCBI Sequence Viewer  
  XP_013967131 (Get FASTA)   NCBI Sequence Viewer  
  XP_022271428 (Get FASTA)   NCBI Sequence Viewer  
  XP_038305878 (Get FASTA)   NCBI Sequence Viewer  
  XP_038305879 (Get FASTA)   NCBI Sequence Viewer  
  XP_038305880 (Get FASTA)   NCBI Sequence Viewer  
  XP_038305881 (Get FASTA)   NCBI Sequence Viewer  
  XP_038305883 (Get FASTA)   NCBI Sequence Viewer  
  XP_038305884 (Get FASTA)   NCBI Sequence Viewer  
  XP_038379327 (Get FASTA)   NCBI Sequence Viewer  
  XP_038379328 (Get FASTA)   NCBI Sequence Viewer  
  XP_038379330 (Get FASTA)   NCBI Sequence Viewer  
  XP_038379331 (Get FASTA)   NCBI Sequence Viewer  
  XP_038379332 (Get FASTA)   NCBI Sequence Viewer  
  XP_038379333 (Get FASTA)   NCBI Sequence Viewer  
  XP_038443297 (Get FASTA)   NCBI Sequence Viewer  
  XP_038443298 (Get FASTA)   NCBI Sequence Viewer  
  XP_038443299 (Get FASTA)   NCBI Sequence Viewer  
  XP_038443300 (Get FASTA)   NCBI Sequence Viewer  
  XP_038443301 (Get FASTA)   NCBI Sequence Viewer  
  XP_038443302 (Get FASTA)   NCBI Sequence Viewer  
  XP_038507810 (Get FASTA)   NCBI Sequence Viewer  
  XP_038507811 (Get FASTA)   NCBI Sequence Viewer  
  XP_038507812 (Get FASTA)   NCBI Sequence Viewer  
  XP_038507813 (Get FASTA)   NCBI Sequence Viewer  
  XP_038507814 (Get FASTA)   NCBI Sequence Viewer  
  XP_038507815 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCAFP00000022990.5
  ENSCAFP00000053562.2
  ENSCAFP00030013432.1
  ENSCAFP00030013608.1
  ENSCAFP00030013792.1
  ENSCAFP00040014679.1
  ENSCAFP00040014795.1
  ENSCAFP00040015006.1
  ENSCAFP00040015179.1
  ENSCAFP00845043222
  ENSCAFP00845043222.1
  ENSCAFP00845043227
  ENSCAFP00845043227.1
RefSeq Acc Id: XP_005641383   ⟸   XM_005641326
- Peptide Label: isoform X4
- UniProtKB: A0A8I3QQ94 (UniProtKB/TrEMBL),   A0A8P0NH53 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_005641385   ⟸   XM_005641328
- Peptide Label: isoform X1
- UniProtKB: A0A8I3QQ94 (UniProtKB/TrEMBL),   A0A8P0NH53 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_013967131   ⟸   XM_014111656
- Peptide Label: isoform X3
- UniProtKB: A0A8I3Q5U6 (UniProtKB/TrEMBL),   A0A8P0P368 (UniProtKB/TrEMBL),   A0A8I3QQ94 (UniProtKB/TrEMBL),   A0A8P0NH53 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_005641384   ⟸   XM_005641327
- Peptide Label: isoform X4
- UniProtKB: A0A8I3QQ94 (UniProtKB/TrEMBL),   A0A8P0NH53 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_005641382   ⟸   XM_005641325
- Peptide Label: isoform X4
- UniProtKB: A0A8I3QQ94 (UniProtKB/TrEMBL),   A0A8P0NH53 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_022271428   ⟸   XM_022415720
- Peptide Label: isoform X2
- UniProtKB: A0A8I3QQ94 (UniProtKB/TrEMBL),   A0A8P0NH53 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSCAFP00000057790   ⟸   ENSCAFT00000088614
Ensembl Acc Id: ENSCAFP00000053674   ⟸   ENSCAFT00000084286
Ensembl Acc Id: ENSCAFP00000053562   ⟸   ENSCAFT00000092977
Ensembl Acc Id: ENSCAFP00000022990   ⟸   ENSCAFT00000024781
Ensembl Acc Id: ENSCAFP00000057585   ⟸   ENSCAFT00000066433
Ensembl Acc Id: ENSCAFP00000049288   ⟸   ENSCAFT00000061245
RefSeq Acc Id: XP_038379332   ⟸   XM_038523404
- Peptide Label: isoform X4
RefSeq Acc Id: XP_038379328   ⟸   XM_038523400
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038379327   ⟸   XM_038523399
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038379330   ⟸   XM_038523402
- Peptide Label: isoform X3
RefSeq Acc Id: XP_038379333   ⟸   XM_038523405
- Peptide Label: isoform X4
RefSeq Acc Id: XP_038379331   ⟸   XM_038523403
- Peptide Label: isoform X4
RefSeq Acc Id: XP_038507814   ⟸   XM_038651886
- Peptide Label: isoform X4
RefSeq Acc Id: XP_038507811   ⟸   XM_038651883
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038507810   ⟸   XM_038651882
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038507812   ⟸   XM_038651884
- Peptide Label: isoform X3
RefSeq Acc Id: XP_038507815   ⟸   XM_038651887
- Peptide Label: isoform X4
RefSeq Acc Id: XP_038507813   ⟸   XM_038651885
- Peptide Label: isoform X4
RefSeq Acc Id: XP_038305883   ⟸   XM_038449955
- Peptide Label: isoform X4
- UniProtKB: A0A8I3QQ94 (UniProtKB/TrEMBL),   A0A8P0NH53 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038305879   ⟸   XM_038449951
- Peptide Label: isoform X2
- UniProtKB: A0A8I3QQ94 (UniProtKB/TrEMBL),   A0A8P0NH53 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038305878   ⟸   XM_038449950
- Peptide Label: isoform X1
- UniProtKB: A0A8I3QQ94 (UniProtKB/TrEMBL),   A0A8P0NH53 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038305880   ⟸   XM_038449952
- Peptide Label: isoform X3
- UniProtKB: A0A8I3Q5U6 (UniProtKB/TrEMBL),   A0A8P0P368 (UniProtKB/TrEMBL),   A0A8I3QQ94 (UniProtKB/TrEMBL),   A0A8P0NH53 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038305884   ⟸   XM_038449956
- Peptide Label: isoform X4
- UniProtKB: A0A8I3QQ94 (UniProtKB/TrEMBL),   A0A8P0NH53 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038305881   ⟸   XM_038449953
- Peptide Label: isoform X4
- UniProtKB: A0A8I3QQ94 (UniProtKB/TrEMBL),   A0A8P0NH53 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038443301   ⟸   XM_038587373
- Peptide Label: isoform X4
- UniProtKB: A0A8C0S234 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038443298   ⟸   XM_038587370
- Peptide Label: isoform X2
- UniProtKB: A0A8C0S234 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038443297   ⟸   XM_038587369
- Peptide Label: isoform X1
- UniProtKB: A0A8C0S234 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038443299   ⟸   XM_038587371
- Peptide Label: isoform X3
- UniProtKB: A0A8C0ML56 (UniProtKB/TrEMBL),   A0A8C0S234 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038443302   ⟸   XM_038587374
- Peptide Label: isoform X4
- UniProtKB: A0A8C0S234 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038443300   ⟸   XM_038587372
- Peptide Label: isoform X4
- UniProtKB: A0A8C0S234 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSCAFP00845043227   ⟸   ENSCAFT00845054976
Ensembl Acc Id: ENSCAFP00845043222   ⟸   ENSCAFT00845054969
Protein Domains
Histone deacetylase   UBP-type

Promoters
RGD ID:13689313
Promoter ID:EPDNEW_C7381
Type:single initiation site
Name:HDAC6_1
Description:histone deacetylase 6
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1X42,005,470 - 42,005,530EPDNEW

Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000015620 Ensembl, UniProtKB/TrEMBL
  ENSCAFG00030008342 UniProtKB/TrEMBL
  ENSCAFG00040009125 UniProtKB/TrEMBL
  ENSCAFG00845030925 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCAFT00000024781.5 UniProtKB/TrEMBL
  ENSCAFT00000092977.2 UniProtKB/TrEMBL
  ENSCAFT00030015404.1 UniProtKB/TrEMBL
  ENSCAFT00030015616.1 UniProtKB/TrEMBL
  ENSCAFT00030015822.1 UniProtKB/TrEMBL
  ENSCAFT00040016937.1 UniProtKB/TrEMBL
  ENSCAFT00040017071.1 UniProtKB/TrEMBL
  ENSCAFT00040017312.1 UniProtKB/TrEMBL
  ENSCAFT00040017497.1 UniProtKB/TrEMBL
  ENSCAFT00845054969 ENTREZGENE
  ENSCAFT00845054969.1 UniProtKB/TrEMBL
  ENSCAFT00845054976 ENTREZGENE
  ENSCAFT00845054976.1 UniProtKB/TrEMBL
Gene3D-CATH 3.30.40.10 UniProtKB/TrEMBL
  3.40.800.20 UniProtKB/TrEMBL
InterPro HDAC_PDAC UniProtKB/TrEMBL
  His_deacetylse UniProtKB/TrEMBL
  His_deacetylse_dom UniProtKB/TrEMBL
  His_deacetylse_dom_sf UniProtKB/TrEMBL
  Ureohydrolase_dom_sf UniProtKB/TrEMBL
  Znf_RING/FYVE/PHD UniProtKB/TrEMBL
  Znf_UBP UniProtKB/TrEMBL
NCBI Gene HDAC6 ENTREZGENE
PANTHER HISTONE DEACETYLASE 6 UniProtKB/TrEMBL
  HISTONE DEACETYLASE HDAC1-RELATED UniProtKB/TrEMBL
Pfam Hist_deacetyl UniProtKB/TrEMBL
  zf-UBP UniProtKB/TrEMBL
PRINTS HDASUPER UniProtKB/TrEMBL
PROSITE ZF_UBP UniProtKB/TrEMBL
SMART ZnF_UBP UniProtKB/TrEMBL
Superfamily-SCOP RING/U-box UniProtKB/TrEMBL
  SSF52768 UniProtKB/TrEMBL
UniProt A0A8C0ML56 ENTREZGENE, UniProtKB/TrEMBL
  A0A8C0MR26_CANLF UniProtKB/TrEMBL
  A0A8C0MRK0_CANLF UniProtKB/TrEMBL
  A0A8C0S234 ENTREZGENE, UniProtKB/TrEMBL
  A0A8C0S277_CANLF UniProtKB/TrEMBL
  A0A8C0S393_CANLF UniProtKB/TrEMBL
  A0A8I3Q5U6 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I3QQ94 ENTREZGENE, UniProtKB/TrEMBL
  A0A8P0NH53 ENTREZGENE, UniProtKB/TrEMBL
  A0A8P0P368 ENTREZGENE, UniProtKB/TrEMBL
VGNC ID VGNC:50630 ENTREZGENE