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ONTOLOGY REPORT - ANNOTATIONS

Term:transport across blood-brain barrier
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Accession:GO:0150104 term browser browse the term
Definition:The directed movement of substances (e.g. macromolecules, small molecules, ions) through the blood-brain barrier.
Synonyms:exact_synonym: transport across BBB
 only_in_taxon: NCBITaxon:6072 ! Eumetazoa


show annotations for term's descendants           Sort by:
transport across blood-brain barrier term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ager advanced glycosylation end product-specific receptor involved_in ISO
IEA		 GO_Central
Ensembl		 GO_REF:0000107 GO_REF:0000119 NCBI chr17:34,816,545...34,819,911
Ensembl chr17:34,816,836...34,819,910 		JBrowse link
G Flvcr2 feline leukemia virus subgroup C cellular receptor 2 acts_upstream_of_or_within
involved_in		 IMP
IDA		 (PMID:38693257)
(PMID:38302740), (PMID:38693257)		 MGI
UniProt		 PMID:38302740 PMID:38693257 NCBI chr12:85,793,313...85,860,359
Ensembl chr12:85,793,313...85,860,359 		JBrowse link
G Lrp1 low density lipoprotein receptor-related protein 1 involved_in IMP (PMID:20630619), (PMID:26619118) ARUK-UCL PMID:20630619 PMID:26619118 NCBI chr10:127,374,026...127,457,158
Ensembl chr10:127,374,030...127,457,017 		JBrowse link
G Slc16a2 solute carrier family 16 (monocarboxylic acid transporters), member 2 involved_in ISO
IEA		 GO_Central
Ensembl		 GO_REF:0000107 GO_REF:0000119 NCBI chr  X:102,741,020...102,865,594
Ensembl chr  X:102,741,020...102,865,589 		JBrowse link
G Slc1a5 solute carrier family 1 (neutral amino acid transporter), member 5 involved_in IDA (PMID:14622120) ARUK-UCL PMID:14622120 NCBI chr 7:16,515,259...16,532,199
Ensembl chr 7:16,515,265...16,532,199 		JBrowse link
G Slc22a5 solute carrier family 22 (organic cation transporter), member 5 involved_in IMP (PMID:14595704) ARUK-UCL PMID:14595704 NCBI chr11:53,755,368...53,782,609
Ensembl chr11:53,755,368...53,782,486 		JBrowse link
G Slc2a1 solute carrier family 2 (facilitated glucose transporter), member 1 acts_upstream_of_or_within
involved_in		 ISO
IEA		 GO_Central
Ensembl		 GO_REF:0000107 GO_REF:0000119 NCBI chr 4:118,966,001...118,994,527
Ensembl chr 4:118,965,908...118,995,180 		JBrowse link
G Slc2a3 solute carrier family 2 (facilitated glucose transporter), member 3 involved_in ISO (PMID:23975336) ARUK-UCL PMID:23975336 NCBI chr 6:122,704,783...122,779,149
Ensembl chr 6:122,704,768...122,778,599 		JBrowse link
G Slc5a1 solute carrier family 5 (sodium/glucose cotransporter), member 1 involved_in ISO GO_Central GO_REF:0000119 NCBI chr 5:33,261,563...33,320,043
Ensembl chr 5:33,261,563...33,320,214 		JBrowse link
G Slc5a6 solute carrier family 5 (sodium-dependent vitamin transporter), member 6 involved_in IEA
ISO		 Ensembl
GO_Central		 GO_REF:0000107 GO_REF:0000119 NCBI chr 5:31,193,380...31,206,268
Ensembl chr 5:31,193,380...31,206,268 		JBrowse link
lipid transport across blood-brain barrier term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd36 CD36 molecule involved_in ISO
IEA		 GO_Central
Ensembl		 GO_REF:0000107 GO_REF:0000119 NCBI chr 5:17,986,680...18,093,828
Ensembl chr 5:17,986,688...18,093,799 		JBrowse link
G Fabp5 fatty acid binding protein 5, epidermal involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:10,077,645...10,081,670
Ensembl chr 3:10,077,608...10,081,667 		JBrowse link
G Mfsd2a MFSD2 lysolipid transporter A, lysophospholipid involved_in IMP
IBA
ISO		 (PMID:24828044) UniProt
GO_Central		 PMID:24828044 GO_REF:0000033 GO_REF:0000119 NCBI chr 4:122,840,643...122,855,844
Ensembl chr 4:122,840,643...122,854,981 		JBrowse link
G Slc27a1 solute carrier family 27 (fatty acid transporter), member 1 involved_in IEA
ISO		 Ensembl
GO_Central		 GO_REF:0000107 GO_REF:0000119 NCBI chr 8:72,021,372...72,039,951
Ensembl chr 8:72,021,526...72,039,946 		JBrowse link
G Slc27a4 solute carrier family 27 (fatty acid transporter), member 4 involved_in IEA
ISO		 Ensembl
GO_Central		 GO_REF:0000107 GO_REF:0000119 NCBI chr 2:29,692,646...29,707,534
Ensembl chr 2:29,692,646...29,707,534 		JBrowse link
negative regulation of lipid transport across blood-brain barrier term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apoe apolipoprotein E involved_in ISO GO_Central GO_REF:0000119 NCBI chr 7:19,430,169...19,434,326
Ensembl chr 7:19,430,034...19,433,113 		JBrowse link
positive regulation of lipid transport across blood-brain barrier term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apoe apolipoprotein E involved_in ISO
IEA		 GO_Central
Ensembl		 GO_REF:0000107 GO_REF:0000119 NCBI chr 7:19,430,169...19,434,326
Ensembl chr 7:19,430,034...19,433,113 		JBrowse link
xenobiotic transport across blood-brain barrier term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb1a ATP-binding cassette, sub-family B member 1A involved_in ISO
IMP		 (PMID:28587984) RGD
GO_Central
ARUK-UCL		 PMID:25053619 PMID:28587984 GO_REF:0000119 RGD:11252095 NCBI chr 5:8,617,091...8,798,575
Ensembl chr 5:8,710,077...8,798,575 		JBrowse link
G Abcb1b ATP-binding cassette, sub-family B member 1B involved_in ISO GO_Central GO_REF:0000119 NCBI chr 5:8,848,147...8,916,314
Ensembl chr 5:8,848,147...8,916,315 		JBrowse link
G Abcc1 ATP-binding cassette, sub-family C member 1 involved_in IEA
ISO		 Ensembl
GO_Central		 GO_REF:0000107 GO_REF:0000119 NCBI chr16:14,179,317...14,292,743
Ensembl chr16:14,179,422...14,293,601 		JBrowse link
G Abcc2 ATP-binding cassette, sub-family member 2 involved_in ISO GO_Central GO_REF:0000096 NCBI chr19:43,770,747...43,826,771
Ensembl chr19:43,770,631...43,829,179 		JBrowse link
G Abcg2 ATP binding cassette subfamily G member 2 (Junior blood group) involved_in ISO GO_Central GO_REF:0000119 NCBI chr 6:58,561,476...58,669,436
Ensembl chr 6:58,561,508...58,672,661 		JBrowse link
G Abcg3 ATP binding cassette subfamily G member 3 involved_in ISO GO_Central GO_REF:0000119 NCBI chr 5:105,082,924...105,130,675
Ensembl chr 5:105,082,923...105,130,584 		JBrowse link
G Slc22a1 solute carrier family 22 (organic cation transporter), member 1 involved_in NAS (PMID:20477935) ARUK-UCL PMID:20477935 NCBI chr17:12,867,761...12,894,725
Ensembl chr17:12,867,756...12,894,716 		JBrowse link
G Slc22a2 solute carrier family 22 (organic cation transporter), member 2 involved_in NAS (PMID:20477935) ARUK-UCL PMID:20477935 NCBI chr17:12,803,076...12,847,376
Ensembl chr17:12,803,019...12,847,375 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 28638
    localization 5656
      establishment of localization 4988
        transport 4665
          vascular transport 25
            transport across blood-brain barrier 24
              copper ion transport across blood-brain barrier 0
              lipid transport across blood-brain barrier + 6
              negative regulation of transport across blood-brain barrier + 1
              positive regulation of transport across blood-brain barrier + 1
              regulation of transport across blood-brain barrier + 1
              xenobiotic transport across blood-brain barrier 8
Path 2
Term Annotations click to browse term
  biological_process 28638
    multicellular organismal process 9056
      system process 3325
        circulatory system process 625
          vascular process in circulatory system 274
            vascular transport 25
              transport across blood-brain barrier 24
                copper ion transport across blood-brain barrier 0
                lipid transport across blood-brain barrier + 6
                negative regulation of transport across blood-brain barrier + 1
                positive regulation of transport across blood-brain barrier + 1
                regulation of transport across blood-brain barrier + 1
                xenobiotic transport across blood-brain barrier 8
paths to the root