Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models   new Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources

ONTOLOGY REPORT - ANNOTATIONS

Term:positive regulation of isotype switching to IgA isotypes
go back to main search page
Accession:GO:0048298 term browser browse the term
Definition:Any process that activates or increases the frequency, rate or extent of isotype switching to IgA isotypes.
Synonyms:exact_synonym: positive regulation of class switch recombination to IgA isotypes;   positive regulation of class switching to IgA isotypes;   positive regulation of isotype switch recombination to IgA isotypes;   up regulation of isotype switching to IgA isotypes;   upregulation of isotype switching to IgA isotypes
 narrow_synonym: activation of isotype switching to IgA isotypes;   stimulation of isotype switching to IgA isotypes


show annotations for term's descendants           Sort by:
positive regulation of isotype switching to IgA isotypes term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mlh1 mutL homolog 1 involved_in IEA
ISO		 GO_REF:0000107
(MGI:1342394|PMID:10430621)		 Ensembl
RGD		 PMID:10430621 GO_REF:0000107 MGI:1342394 NCBI chr 8:111,196,468...111,233,721
Ensembl chr 8:111,196,468...111,233,617 		JBrowse link
G Msh2 mutS homolog 2 involved_in IEA
ISO		 GO_REF:0000107
(MGI:1342394|PMID:10430621)		 Ensembl
RGD		 PMID:10430621 GO_REF:0000107 MGI:1342394 NCBI chr 6:6,813,793...6,872,960
Ensembl chr 6:6,813,795...6,872,938 		JBrowse link
G Nsd2 nuclear receptor binding SET domain protein 2 acts_upstream_of_or_within ISO (PMID:23241889) RGD PMID:23241889 NCBI chr14:76,833,179...76,911,304
Ensembl chr14:76,835,637...76,913,641 		JBrowse link
G Pms2 PMS1 homolog 2, mismatch repair system component involved_in ISO UniProtKB:Q9JK91 (MGI:1342394|PMID:10430621) RGD PMID:10430621 MGI:1342394 NCBI chr12:10,676,818...10,701,161
Ensembl chr12:10,676,764...10,701,066 		JBrowse link
G Tgfb1 transforming growth factor, beta 1 involved_in
acts_upstream_of_or_within		 ISS
ISO		 GO_REF:0000024
(PMID:14988498)		 AgBase
RGD		 PMID:14988498 GO_REF:0000024 NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847 		JBrowse link
G Tnfsf13 TNF superfamily member 13 acts_upstream_of_or_within
involved_in		 ISO
IBA		 (PMID:14988498)
MGI:3038886 (PMID:14988498)
GO_REF:0000033		 RGD
GO_Central		 PMID:14988498 GO_REF:0000033 NCBI chr10:54,400,054...54,403,723
Ensembl chr10:54,400,065...54,403,042 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19694
    developmental process 6963
      positive regulation of developmental process 1562
        positive regulation of isotype switching 31
          positive regulation of isotype switching to IgA isotypes 6
Path 2
Term Annotations click to browse term
  biological_process 19694
    metabolic process 11456
      organic substance metabolic process 10971
        organic cyclic compound metabolic process 6031
          nucleobase-containing compound metabolic process 5524
            nucleic acid metabolic process 4949
              DNA metabolic process 949
                DNA recombination 343
                  somatic cell DNA recombination 78
                    somatic diversification of immune receptors via germline recombination within a single locus 78
                      somatic recombination of immunoglobulin gene segments 66
                        somatic recombination of immunoglobulin genes involved in immune response 58
                          isotype switching 58
                            regulation of isotype switching 41
                              positive regulation of isotype switching 31
                                positive regulation of isotype switching to IgA isotypes 6
paths to the root