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ONTOLOGY REPORT - ANNOTATIONS

Term:negative regulation of translational initiation
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Accession:GO:0045947 term browser browse the term
Definition:Any process that stops, prevents, or reduces the frequency, rate or extent of translational initiation.
Synonyms:exact_synonym: down regulation of translational initiation;   downregulation of translational initiation
 narrow_synonym: inhibition of translational initiation


show annotations for term's descendants           Sort by:
negative regulation of translational initiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ago2 argonaute RISC catalytic subunit 2 involved_in ISO
ISS		 GO_Central
UniProt		 GO_REF:0000024 GO_REF:0000119 NCBI chr15:72,967,693...73,056,777
Ensembl chr15:72,967,693...73,056,784 		JBrowse link
G Bank1 B cell scaffold protein with ankyrin repeats 1 acts_upstream_of_or_within IMP (PMID:24227780) MGI PMID:24227780 NCBI chr 3:135,759,124...136,031,902
Ensembl chr 3:135,759,124...136,031,827 		JBrowse link
G Bc1 brain cytoplasmic RNA 1 acts_upstream_of_or_within ISO MGI GO_REF:0000008 NCBI chr 7:144,468,207...144,468,360
Ensembl chr 7:144,468,199...144,468,374 		JBrowse link
G Eif2ak4 eukaryotic translation initiation factor 2 alpha kinase 4 involved_in IDA (PMID:16601681) UniProt PMID:16601681 NCBI chr 2:118,219,065...118,305,715
Ensembl chr 2:118,219,099...118,305,715 		JBrowse link
G Eif4e2 eukaryotic translation initiation factor 4E member 2 involved_in ISO GO_Central GO_REF:0000119 NCBI chr 1:87,141,633...87,168,210
Ensembl chr 1:87,141,636...87,168,210 		JBrowse link
G Eif4ebp1 eukaryotic translation initiation factor 4E binding protein 1 acts_upstream_of_or_within
involved_in		 ISO
IDA
IBA		 (PMID:16142217) RGD
MGI
GO_Central		 PMID:11865047 PMID:16142217 GO_REF:0000033 GO_REF:0000096 GO_REF:0000119 RGD:1625627 NCBI chr 8:27,750,355...27,765,684
Ensembl chr 8:27,750,357...27,766,702 		JBrowse link
G Eif4ebp2 eukaryotic translation initiation factor 4E binding protein 2 involved_in ISO
IMP
ISS
IBA		 (PMID:16237163), (PMID:20347422), (PMID:23172145) GO_Central
UniProt		 PMID:16237163 PMID:20347422 PMID:23172145 GO_REF:0000024 GO_REF:0000033 GO_REF:0000119 NCBI chr10:61,268,276...61,288,448
Ensembl chr10:61,264,270...61,288,440 		JBrowse link
G Eif4ebp3 eukaryotic translation initiation factor 4E binding protein 3 involved_in IEA
IBA		 UniProt
GO_Central		 GO_REF:0000033 GO_REF:0000117 NCBI chr18:36,797,113...36,799,377
Ensembl chr18:36,797,113...36,798,970 		JBrowse link
G Fmr1 fragile X messenger ribonucleoprotein 1 involved_in IDA (PMID:18805096) UniProt PMID:18805096 NCBI chr  X:67,722,144...67,761,569
Ensembl chr  X:67,722,147...67,761,569 		JBrowse link
G Gigyf2 GRB10 interacting GYF protein 2 involved_in ISO
IEA		 GO_Central
Ensembl		 GO_REF:0000107 GO_REF:0000119 NCBI chr 1:87,254,653...87,378,532
Ensembl chr 1:87,254,720...87,378,518 		JBrowse link
G Larp1 La ribonucleoprotein 1, translational regulator involved_in ISO
ISS		 GO_Central
UniProt		 GO_REF:0000024 GO_REF:0000119 NCBI chr11:57,899,711...57,952,860
Ensembl chr11:57,899,890...57,952,860 		JBrowse link
G Paip2 polyadenylate-binding protein-interacting protein 2 involved_in ISO
IEA		 GO_Central
Ensembl		 GO_REF:0000107 GO_REF:0000119 NCBI chr18:35,731,649...35,750,239
Ensembl chr18:35,731,670...35,750,240 		JBrowse link
G Paip2b poly(A) binding protein interacting protein 2B involved_in ISS
ISO		 UniProt
GO_Central		 GO_REF:0000024 GO_REF:0000119 NCBI chr 6:83,783,040...83,808,723
Ensembl chr 6:83,782,383...83,808,723 		JBrowse link
G Rbm4 RNA binding motif protein 4 involved_in ISS
ISO		 UniProt
GO_Central		 GO_REF:0000024 GO_REF:0000119 NCBI chr19:4,834,321...4,844,037
Ensembl chr19:4,834,321...4,843,929 		JBrowse link
G Scrib scribbled planar cell polarity involved_in ISO GO_Central GO_REF:0000119 NCBI chr15:75,919,011...75,941,633
Ensembl chr15:75,919,007...75,941,633 		JBrowse link
G Tpr translocated promoter region, nuclear basket protein involved_in ISO
ISS		 GO_Central
UniProt		 GO_REF:0000024 GO_REF:0000119 NCBI chr 1:150,268,544...150,325,686
Ensembl chr 1:150,268,589...150,325,686 		JBrowse link
G Zfp598 zinc finger protein 598 involved_in ISO GO_Central GO_REF:0000119 NCBI chr17:24,888,661...24,900,997
Ensembl chr17:24,888,661...24,900,990 		JBrowse link
negative regulation of formation of translation preinitiation complex term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Rpl13a ribosomal protein L13A involved_in ISO
IEA		 GO_Central
Ensembl		 GO_REF:0000107 GO_REF:0000119 NCBI chr 7:44,774,987...44,778,169
Ensembl chr 7:44,774,982...44,778,185 		JBrowse link
negative regulation of translation in response to oxidative stress term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pml promyelocytic leukemia involved_in ISO GO_Central GO_REF:0000119 NCBI chr 9:58,125,359...58,157,077
Ensembl chr 9:58,125,359...58,157,069 		JBrowse link
negative regulation of translational initiation in response to stress term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Eif2ak4 eukaryotic translation initiation factor 2 alpha kinase 4 involved_in IDA
IBA		 (PMID:12176355) UniProt
GO_Central		 PMID:12176355 GO_REF:0000033 NCBI chr 2:118,219,065...118,305,715
Ensembl chr 2:118,219,099...118,305,715 		JBrowse link
G Eif2s1 eukaryotic translation initiation factor 2, subunit 1 alpha involved_in IDA (PMID:12176355) UniProt PMID:12176355 NCBI chr12:78,908,846...78,933,784
Ensembl chr12:78,908,593...78,933,784 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 28635
    cellular process 18392
      metabolic process 11624
        translational initiation 132
          negative regulation of translational initiation 20
            negative regulation of cytoplasmic translational initiation + 1
            negative regulation of formation of translation initiation ternary complex 0
            negative regulation of mitochondrial translational initiation 0
            negative regulation of translational initiation by iron 0
            negative regulation of translational initiation in response to stress + 3
Path 2
Term Annotations click to browse term
  biological_process 28635
    biological regulation 13450
      regulation of biological process 13009
        regulation of cellular process 12632
          regulation of metabolic process 6975
            regulation of biosynthetic process 5711
              regulation of macromolecule biosynthetic process 5492
                regulation of gene expression 5373
                  post-transcriptional regulation of gene expression 807
                    regulation of translation 477
                      regulation of translational initiation 72
                        negative regulation of translational initiation 20
                          negative regulation of cytoplasmic translational initiation + 1
                          negative regulation of formation of translation initiation ternary complex 0
                          negative regulation of mitochondrial translational initiation 0
                          negative regulation of translational initiation by iron 0
                          negative regulation of translational initiation in response to stress + 3
paths to the root