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Gene: Eif2ak4 (eukaryotic translation initiation factor 2 alpha kinase 4) Mus musculus
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Symbol: Eif2ak4
Name: eukaryotic translation initiation factor 2 alpha kinase 4
Description: Exhibits eukaryotic translation initiation factor 2alpha kinase activity and tRNA binding activity. Involved in several processes, including generation of neurons; learning or memory; and regulation of translational initiation. Localizes to the polysome. Human ortholog(s) of this gene implicated in pulmonary venoocclusive disease. Is expressed in brain; oocyte; and ovary. Orthologous to human EIF2AK4 (eukaryotic translation initiation factor 2 alpha kinase 4); PARTICIPATES IN Endoplasmic Reticulum-associated degradation pathway; hepatitis C pathway; influenza A pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 4-vinylcyclohexene dioxide; amino acid.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 2610011M03; eIF-2-alpha kinase GCN2; eukaryotic translation initiation factor 2-alpha kinase 4; GCN2; GCN2 eIF2alpha kinase; GCN2-like protein; MGCN2
Orthologs:
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm382118,388,583 - 118,475,234 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv372118,214,353 - 118,300,970 (+)NCBIGRCm37mm9NCBIm37
MGSCv362118,080,058 - 118,166,674 (+)NCBImm8
Celera2119,539,566 - 119,626,375 (+)NCBICelera
Cytogenetic Map2 E5NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Eif2ak4
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1332170
Created: 2005-02-01
Species: Mus musculus
Last Modified: 2019-10-16
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.