Larp1 (La ribonucleoprotein domain family, member 1) - Rat Genome Database
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Gene: Larp1 (La ribonucleoprotein domain family, member 1) Mus musculus
Analyze
Symbol: Larp1
Name: La ribonucleoprotein domain family, member 1
RGD ID: 1550388
MGI Page MGI
Description: Predicted to have eukaryotic initiation factor 4E binding activity; nucleic acid binding activity; and ribosomal small subunit binding activity. Predicted to be involved in several processes, including TORC1 signaling; cellular response to rapamycin; and posttranscriptional regulation of gene expression. Predicted to colocalize with TORC1 complex and polysomal ribosome. Is expressed in several structures, including branchial arch; cranial ganglion; epithelium; future spinal cord; and limb bud. Orthologous to human LARP1 (La ribonucleoprotein 1, translational regulator); INTERACTS WITH 1,2-dimethylhydrazine; 2,3',4,4',5-Pentachlorobiphenyl; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 1810024J12Rik; 3110040D16Rik; la related protein; la-related protein 1; Larp; mKIAA0731
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Related Pseudogenes: Gm16425  
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391157,899,711 - 57,952,860 (+)NCBIGRCm39mm39
GRCm381157,973,418 - 58,062,034 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1158,009,064 - 58,062,034 (+)EnsemblGRCm38mm10GRCm38
MGSCv371157,822,566 - 57,875,536 (+)NCBIGRCm37mm9NCBIm37
MGSCv361157,824,441 - 57,878,230 (+)NCBImm8
MGSCv361158,519,580 - 58,571,809 (+)NCBImm8
Celera1162,767,009 - 62,819,040 (+)NCBICelera
Cytogenetic Map11B1.3NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


References

Additional References at PubMed
PMID:8889548   PMID:10349636   PMID:10878606   PMID:10922068   PMID:11042159   PMID:11076861   PMID:12477932   PMID:12520002   PMID:12904583   PMID:14610273   PMID:15489334   PMID:15741177  
PMID:16141072   PMID:16141073   PMID:17967808   PMID:18799693   PMID:26265008   PMID:30196744   PMID:30457570   PMID:31138677   PMID:31366290   PMID:32098917   PMID:32325033   PMID:32581705  
PMID:33483593  


Genomics

Comparative Map Data
Larp1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391157,899,711 - 57,952,860 (+)NCBIGRCm39mm39
GRCm381157,973,418 - 58,062,034 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1158,009,064 - 58,062,034 (+)EnsemblGRCm38mm10GRCm38
MGSCv371157,822,566 - 57,875,536 (+)NCBIGRCm37mm9NCBIm37
MGSCv361157,824,441 - 57,878,230 (+)NCBImm8
MGSCv361158,519,580 - 58,571,809 (+)NCBImm8
Celera1162,767,009 - 62,819,040 (+)NCBICelera
Cytogenetic Map11B1.3NCBI
LARP1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl5154,712,843 - 154,817,605 (+)EnsemblGRCh38hg38GRCh38
GRCh385154,682,979 - 154,817,605 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh375154,062,539 - 154,197,165 (+)NCBIGRCh37GRCh37hg19GRCh37
GRCh375154,062,224 - 154,197,167 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 365154,072,655 - 154,177,358 (+)NCBINCBI36hg18NCBI36
Celera5150,169,448 - 150,274,651 (+)NCBI
Cytogenetic Map5q33.2NCBI
HuRef5149,234,294 - 149,339,464 (+)NCBIHuRef
CHM1_15153,524,904 - 153,629,585 (+)NCBICHM1_1
Larp1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21042,191,378 - 42,246,361 (+)NCBI
Rnor_6.0 Ensembl1043,446,526 - 43,498,066 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.01043,435,738 - 43,501,186 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01043,243,479 - 43,297,161 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41043,608,207 - 43,676,236 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11043,646,021 - 43,688,503 (+)NCBI
Celera1041,482,583 - 41,536,302 (+)NCBICelera
Cytogenetic Map10q22NCBI
Larp1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554089,002,458 - 9,080,938 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554089,002,443 - 9,080,938 (+)NCBIChiLan1.0ChiLan1.0
LARP1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.15156,083,059 - 156,216,706 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl5156,112,358 - 156,216,706 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v05150,086,829 - 150,221,401 (+)NCBIMhudiblu_PPA_v0panPan3
LARP1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1 Ensembl454,994,227 - 55,017,098 (-)EnsemblCanFam3.1canFam3CanFam3.1
CanFam3.1454,991,528 - 55,045,976 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Larp1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
SpeTri2.0NW_0049365158,039,887 - 8,125,006 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
LARP1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1668,390,875 - 68,484,918 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11668,390,879 - 68,451,605 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21674,312,951 - 74,401,405 (-)NCBISscrofa10.2Sscrofa10.2susScr3
LARP1
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12357,126,878 - 57,265,243 (+)NCBI
ChlSab1.1 Ensembl2357,238,336 - 57,261,710 (+)Ensembl
Larp1
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462473334,504,259 - 34,593,223 (-)NCBI

Position Markers
RH135912  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381158,057,261 - 58,058,610UniSTSGRCm38
GRCm38819,538,252 - 19,538,431UniSTSGRCm38
MGSCv37819,538,252 - 19,538,431UniSTSGRCm37
MGSCv371157,870,763 - 57,872,112UniSTSGRCm37
Celera819,702,840 - 19,703,019UniSTS
Celera1162,814,249 - 62,815,598UniSTS
Cytogenetic Map11B2UniSTS
Cytogenetic Map8A1.3UniSTS
UniSTS:236586  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381158,057,656 - 58,057,857UniSTSGRCm38
MGSCv371157,871,158 - 57,871,359UniSTSGRCm37
Celera1162,814,644 - 62,814,845UniSTS
Cytogenetic Map11B2UniSTS
C88147  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381346,679,946 - 46,680,062UniSTSGRCm38
GRCm381158,038,458 - 58,038,574UniSTSGRCm38
MGSCv371346,775,315 - 46,775,431UniSTSGRCm37
MGSCv371157,851,960 - 57,852,076UniSTSGRCm37
Celera1347,763,463 - 47,763,579UniSTS
Cytogenetic Map11B2UniSTS
Cytogenetic Map13A5UniSTS
Whitehead/MRC_RH13483.49UniSTS
AI136666  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381158,057,341 - 58,057,539UniSTSGRCm38
MGSCv371157,870,843 - 57,871,041UniSTSGRCm37
Celera1162,814,329 - 62,814,527UniSTS
Cytogenetic Map11B2UniSTS


QTLs in Region (GRCm38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
27226798Scvln18_msacral vertebrae length 2, 16 week (mouse)11330000060800000Mouse
26884446Sklq10_mskull length QTL 10, 10 week (mouse)11330000063000000Mouse
26884453Sklq16_mskull length QTL 16, 16 week (mouse)11330000072800000Mouse
13208559Wght10_mweight 10 (mouse)11400000089000000Mouse
13208558Lgth12_mbody length 12 (mouse)11400000095000000Mouse
1300905Scc6_mcolon tumor susceptibility 6 (mouse)Not determined11693027789128908Mouse
27226738Metcl11_mmetatarsal-calcaneal length 11, 10 week (mouse)11890000061500000Mouse
26884401Huml4_mhumerus length 4, 10 week (mouse)111160000068600000Mouse
27226762Feml21_mfemur length 21, 16 week (mouse)111180000066100000Mouse
4141966Tailq1_mtail length QTL 1 (mouse)Not determined1231863768609504Mouse
1357851Scfq3_msubcutaneous fat pad weight QTL 3 (mouse)Not determined111231863768609504Mouse
1357437Epfq4_mepididymal fat pad weight QTL 4 (mouse)Not determined111231863768609504Mouse
4141127W3q4_mweight 3 weeks QTL 4 (mouse)Not determined1231863768609504Mouse
4142216Lgq1_mlate growth QTL 1 (mouse)Not determined1231863768609504Mouse
4142308W6q3_mweight 6 weeks QTL 3 (mouse)Not determined111231863768609504Mouse
4141582Lgaq1_mlate growth adjusted QTL 1 (mouse)Not determined1231863768609504Mouse
4142109W10q2_mweight 10 weeks QTL 2 (mouse)Not determined1231863768609504Mouse
4141470Egq4_mearly growth QTL 4 (mouse)Not determined1231863768609504Mouse
1357640Orq2_movulation rate QTL 2 (mouse)Not determined111231863768609504Mouse
1357720Kidpq1_mkidney weight percentage QTL 1 (mouse)Not determined111231863768609504Mouse
1559002Lmrq4_mLeishmania major resistance QTL 4 (mouse)Not determined111231863769794121Mouse
1357859Lvrq7_mliver weight QTL 7 (mouse)Not determined1112318637118131898Mouse
39128214Lwq20_mliver weight QTL 20 (mouse)1112318637118131898Mouse
1558945Orgwq8_morgan weight QTL 8 (mouse)Not determined111710617567187585Mouse
10053687Eae6_msusceptibility to experimental allergic encephalomyelitis 6 (mouse)Not determined111783196668609504Mouse
4141894Nidd6k_mNidd6 on KK-A (mouse)Not determined1917420497007000Mouse
10412246Dfs2_mdental fluorosis suseptibility 2 (mouse)Not determined112185736495990405Mouse
10044006Hbnr13_mHeligmosomoides bakeri nematode resistance 13 (mouse)Not determined112588179959881914Mouse
1357844Si5lq5_mserum IGFBP-5 level QTL 5 (mouse)Not determined112827504662275149Mouse
13524848Ppiq7_mprepulse inhibition QTL 7 (mouse)112867832062678320Mouse
1301426Desp2_mdespair 2 (mouse)Not determined112881775462817873Mouse
11522752Cocia18_mcocaine-induced activity, QTL 18 (mouse)113111738265117382Mouse
11059563Lmr31_mleishmaniasis resistance 31 (mouse)113220975066209867Mouse
1357782Char8_mP. chabaudi malaria resistance QTL 8 (mouse)Not determined113568778969794161Mouse
13208569Bmiq10_mbody mass index QTL 10 (mouse)113600000085000000Mouse
1301328Mol4_mmodifier of LPS-response 4 (mouse)Not determined113639175083590530Mouse
1301788Lbw8_mlupus NZB x NZW 8 (mouse)Not determined113661246070618665Mouse
1301896Tria1_mT-cell receptor induced activation 1 (mouse)Not determined113672273870723028Mouse
4141853Skmw17_mskeletal muscle weight 17 (mouse)Not determined113719011571190238Mouse
4142475Ity2a_mimmunity to S. typhimurium 2a (mouse)Not determined113787775360511890Mouse
10766457Nwa3_mNew Zealand White autoimmunity 3 (mouse)113812528972125383Mouse
11532698Sluc36a_msusceptibility to lung cancer 36a (mouse)114236579176365904Mouse
11532699Sluc36b_msusceptibility to lung cancer 36b (mouse)114236579176365904Mouse
4142300Ctrq3_mC. trachomatis resistance QTL 3 (mouse)Not determined114473921176963931Mouse
4141367Inf1_macute ozone induced inflammation (mouse)Not determined44739211113167183Mouse
4141000Nidd3_mnon-insulin-dependent diabetes mellitus 3 (mouse)Not determined4515120179151308Mouse
1302021Nidd1n_mnon-insulin-dependent diabetes mellitus 1 in NSY (mouse)Not determined114527504680087498Mouse
1357878Mastr_mmodifier of astrocytoma (mouse)Not determined114581775489927907Mouse
1300765Bbaa4_mB.burgdorferi-associated arthritis 4 (mouse)Not determined114629434180294436Mouse
1301988Bmd11_mbone mineral density 11 (mouse)Not determined114642858180428696Mouse
1301830Ssta4_msusceptibility to Salmonella typhimurium antigens 4 (mouse)Not determined115018736584187585Mouse
13524840Ppiq9a_mprepulse inhibition QTL 9a (mouse)115260355986603559Mouse
1300774Pgia7_mproteoglycan induced arthritis 7 (mouse)Not determined115349976287499911Mouse
4141084Spqq1_msperm quality QTL 1 (mouse)Not determined5417484463428696Mouse
1302186Blmpf2_mbleomycin-induced pulmonary fibrosis 2 (mouse)Not determined115417484467187585Mouse
4142148Ckdbp2_mchronic kidney disease blood pressure locus 2 (mouse)Not determined115419011565213015Mouse
4141830Pregq1_mpregnancy QTL 1 (mouse)Not determined115423592683842826Mouse
4141875Etax9_methanol induced ataxia 9 (mouse)Not determined5539415972319101Mouse
4142121Tmc1m2_mTmc1 modifier 2 (mouse)Not determined1156973201114267131Mouse
1300664Etohcta9_methanol conditioned taste aversion 9 (mouse)Not determined115786383491863932Mouse

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:2632
Count of miRNA genes:687
Interacting mature miRNAs:840
Transcripts:ENSMUST00000071487, ENSMUST00000140500, ENSMUST00000178636
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSMUST00000071487   ⟹   ENSMUSP00000071421
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl1158,009,064 - 58,062,031 (+)Ensembl
RefSeq Acc Id: ENSMUST00000140500
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl1158,041,613 - 58,043,013 (+)Ensembl
RefSeq Acc Id: ENSMUST00000178636   ⟹   ENSMUSP00000136673
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl1158,009,064 - 58,062,034 (+)Ensembl
RefSeq Acc Id: NM_028451   ⟹   NP_082727
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391157,899,890 - 57,952,860 (+)NCBI
GRCm381158,009,064 - 58,062,034 (+)NCBI
MGSCv371157,822,566 - 57,875,536 (+)RGD
Celera1162,767,009 - 62,819,040 (+)RGD
cM Map11 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_006534334   ⟹   XP_006534397
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391157,900,601 - 57,952,860 (+)NCBI
GRCm381158,009,766 - 58,062,034 (+)NCBI
Sequence:
RefSeq Acc Id: XM_036157022   ⟹   XP_036012915
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391157,899,711 - 57,952,860 (+)NCBI
Reference Sequences
RefSeq Acc Id: NP_082727   ⟸   NM_028451
- UniProtKB: Q6ZQ58 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_006534397   ⟸   XM_006534334
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: ENSMUSP00000071421   ⟸   ENSMUST00000071487
RefSeq Acc Id: ENSMUSP00000136673   ⟸   ENSMUST00000178636
RefSeq Acc Id: XP_036012915   ⟸   XM_036157022
- Peptide Label: isoform X2
Protein Domains
HTH La-type RNA-binding

Promoters
RGD ID:6821185
Promoter ID:MM_KWN:7525
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day1,   3T3L1_Day2,   3T3L1_Day3,   3T3L1_Day4,   BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   ES_Cell,   Kidney,   Liver,   MEF_B4
Transcripts:AK019141_2510010K19RIK,   NM_028451,   OTTMUST00000012716
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361157,822,036 - 57,822,567 (+)MPROMDB
RGD ID:6820307
Promoter ID:MM_KWN:7528
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:BoneMarrow_2Hour,   BoneMarrow_4Hour,   Brain,   Kidney,   Lung
Transcripts:UC007JAI.1
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361157,873,864 - 57,874,364 (+)MPROMDB
RGD ID:8674742
Promoter ID:EPDNEW_M15398
Type:initiation region
Name:Larp1_1
Description:Mus musculus La ribonucleoprotein domain family, member 1 , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381158,009,139 - 58,009,199EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:1890165 AgrOrtholog
Ensembl Genes ENSMUSG00000037331 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ENSMUSG00000069876
Ensembl Protein ENSMUSP00000071421 UniProtKB/TrEMBL
  ENSMUSP00000136673 ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSMUST00000071487 UniProtKB/TrEMBL
  ENSMUST00000178636 ENTREZGENE, UniProtKB/Swiss-Prot
Gene3D-CATH 1.10.10.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro DM15 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  La_HTH UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  WH-like_DNA-bd_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  WH_DNA-bd_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:73158 UniProtKB/Swiss-Prot
MGD MGI:1890165 ENTREZGENE
NCBI Gene 73158 ENTREZGENE
Pfam PF05383 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Larp1 PhenoGen
PROSITE HTH_LA UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART DM15 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SM00715 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF46785 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt LARP1_MOUSE UniProtKB/Swiss-Prot
  Q3TEA9_MOUSE UniProtKB/TrEMBL
  Q3UU34_MOUSE UniProtKB/TrEMBL
  Q6ZQ58 ENTREZGENE
  Z4YJT3_MOUSE UniProtKB/TrEMBL
UniProt Secondary A2AFQ8 UniProtKB/Swiss-Prot
  J3QNB1 UniProtKB/Swiss-Prot
  Q7TSF7 UniProtKB/Swiss-Prot