Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | (1->4)-beta-D-glucan | multiple interactions | EXP | | 6480464 | [perfluorooctane sulfonic acid co-treated with Cellulose] results in decreased expression of LARP1 mRNA | CTD | PMID:36331819 | 1,2-dimethylhydrazine | increases expression | EXP | | 6480464 | 1 and 2-Dimethylhydrazine results in increased expression of LARP1 mRNA | CTD | PMID:22206623 | 17beta-estradiol | increases expression | ISO | LARP1 (Homo sapiens) | 6480464 | Estradiol results in increased expression of LARP1 mRNA | CTD | PMID:23019147 and PMID:31614463 | 17beta-estradiol | increases phosphorylation | ISO | LARP1 (Homo sapiens) | 6480464 | Estradiol results in increased phosphorylation of LARP1 protein | CTD | PMID:27026707 | 2,3',4,4',5-Pentachlorobiphenyl | increases expression | EXP | | 6480464 | 2 more ... | CTD | PMID:31388691 | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | ISO | Larp1 (Rattus norvegicus) | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of LARP1 mRNA | CTD | PMID:21215274 and PMID:33387578 | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | ISO | Larp1 (Rattus norvegicus) | 6480464 | Tetrachlorodibenzodioxin results in increased expression of LARP1 mRNA | CTD | PMID:32109520 | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | EXP | | 6480464 | Tetrachlorodibenzodioxin affects the expression of LARP1 mRNA | CTD | PMID:24680724 | 2,4,6-tribromophenol | decreases expression | ISO | LARP1 (Homo sapiens) | 6480464 | 2 more ... | CTD | PMID:31675489 | 2,4-dinitrotoluene | affects expression | ISO | Larp1 (Rattus norvegicus) | 6480464 | 2 and 4-dinitrotoluene affects the expression of LARP1 mRNA | CTD | PMID:21346803 | 2,6-dinitrotoluene | affects expression | ISO | Larp1 (Rattus norvegicus) | 6480464 | 2 and 6-dinitrotoluene affects the expression of LARP1 mRNA | CTD | PMID:21346803 | 3-isobutyl-1-methyl-7H-xanthine | multiple interactions | ISO | LARP1 (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in decreased expression of LARP1 mRNA | CTD | PMID:28628672 | 4,4'-sulfonyldiphenol | increases expression | ISO | LARP1 (Homo sapiens) | 6480464 | bisphenol S results in increased expression of LARP1 protein | CTD | PMID:34186270 | 4-amino-2,6-dinitrotoluene | affects expression | ISO | Larp1 (Rattus norvegicus) | 6480464 | 4-amino-2 and 6-dinitrotoluene affects the expression of LARP1 mRNA | CTD | PMID:21346803 | aflatoxin B1 | decreases methylation | ISO | LARP1 (Homo sapiens) | 6480464 | Aflatoxin B1 results in decreased methylation of LARP1 gene | CTD | PMID:27153756 | amino acid | increases response to substance | ISO | LARP1 (Homo sapiens) | 6480464 | LARP1 protein results in increased susceptibility to Amino Acids deficiency | CTD | PMID:25940091 | amino acid | multiple interactions | ISO | LARP1 (Homo sapiens) | 6480464 | Amino Acids deficiency inhibits the reaction [[MTOR protein binds to RAPTOR protein] which binds to LARP1 protein] more ... | CTD | PMID:25940091 | amphetamine | decreases expression | ISO | Larp1 (Rattus norvegicus) | 6480464 | Amphetamine results in decreased expression of LARP1 mRNA | CTD | PMID:30779732 | aristolochic acid A | decreases expression | ISO | LARP1 (Homo sapiens) | 6480464 | aristolochic acid I results in decreased expression of LARP1 mRNA | CTD | PMID:33212167 | benzo[a]pyrene | decreases methylation | ISO | LARP1 (Homo sapiens) | 6480464 | Benzo(a)pyrene results in decreased methylation of LARP1 exon | CTD | PMID:27901495 | benzo[a]pyrene | affects methylation | ISO | LARP1 (Homo sapiens) | 6480464 | Benzo(a)pyrene affects the methylation of LARP1 promoter | CTD | PMID:27901495 | bis(2-chloroethyl) sulfide | increases phosphorylation | ISO | LARP1 (Homo sapiens) | 6480464 | Mustard Gas results in increased phosphorylation of LARP1 protein | CTD | PMID:19845377 | bisphenol A | decreases expression | EXP | | 6480464 | bisphenol A results in decreased expression of LARP1 mRNA | CTD | PMID:23798566 | bisphenol A | decreases expression | ISO | LARP1 (Homo sapiens) | 6480464 | bisphenol A results in decreased expression of LARP1 protein | CTD | PMID:31675489 | bisphenol A | increases expression | ISO | Larp1 (Rattus norvegicus) | 6480464 | bisphenol A results in increased expression of LARP1 mRNA | CTD | PMID:32145629 | bisphenol A | affects expression | ISO | Larp1 (Rattus norvegicus) | 6480464 | bisphenol A affects the expression of LARP1 mRNA | CTD | PMID:25181051 | Bisphenol B | increases expression | ISO | LARP1 (Homo sapiens) | 6480464 | bisphenol B results in increased expression of LARP1 protein | CTD | PMID:34186270 | bisphenol F | multiple interactions | ISO | LARP1 (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in decreased expression of LARP1 mRNA | CTD | PMID:28628672 | bisphenol F | increases expression | ISO | LARP1 (Homo sapiens) | 6480464 | bisphenol F results in increased expression of LARP1 protein | CTD | PMID:34186270 | Brodifacoum | decreases expression | ISO | Larp1 (Rattus norvegicus) | 6480464 | bromfenacoum results in decreased expression of LARP1 protein | CTD | PMID:28903499 | caffeine | affects phosphorylation | ISO | LARP1 (Homo sapiens) | 6480464 | Caffeine affects the phosphorylation of LARP1 protein | CTD | PMID:35688186 | cisplatin | decreases expression | ISO | LARP1 (Homo sapiens) | 6480464 | Cisplatin results in decreased expression of LARP1 mRNA | CTD | PMID:27594783 | clobetasol | decreases expression | EXP | | 6480464 | Clobetasol results in decreased expression of LARP1 mRNA | CTD | PMID:27462272 | clofibric acid | affects expression | ISO | Larp1 (Rattus norvegicus) | 6480464 | Clofibric Acid affects the expression of LARP1 mRNA | CTD | PMID:17602206 | cobalt dichloride | increases expression | ISO | LARP1 (Homo sapiens) | 6480464 | cobaltous chloride results in increased expression of LARP1 mRNA | CTD | PMID:19320972 | coumarin | affects phosphorylation | ISO | LARP1 (Homo sapiens) | 6480464 | coumarin affects the phosphorylation of LARP1 protein | CTD | PMID:35688186 | decabromodiphenyl ether | increases expression | ISO | LARP1 (Homo sapiens) | 6480464 | decabromobiphenyl ether results in increased expression of LARP1 protein | CTD | PMID:31675489 | dexamethasone | multiple interactions | ISO | LARP1 (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in decreased expression of LARP1 mRNA | CTD | PMID:28628672 | dextran sulfate | decreases expression | EXP | | 6480464 | Dextran Sulfate results in decreased expression of LARP1 protein | CTD | PMID:32272095 | dextran sulfate | multiple interactions | EXP | | 6480464 | Erianin inhibits the reaction [Dextran Sulfate results in decreased expression of LARP1 protein] | CTD | PMID:32272095 | dibutyl phthalate | decreases expression | EXP | | 6480464 | Dibutyl Phthalate results in decreased expression of LARP1 mRNA | CTD | PMID:17361019 | dicrotophos | increases expression | ISO | LARP1 (Homo sapiens) | 6480464 | dicrotophos results in increased expression of LARP1 mRNA | CTD | PMID:28302478 | dorsomorphin | multiple interactions | ISO | LARP1 (Homo sapiens) | 6480464 | [NOG protein co-treated with methylmercuric chloride co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of LARP1 mRNA | CTD | PMID:27188386 | doxorubicin | decreases expression | ISO | LARP1 (Homo sapiens) | 6480464 | Doxorubicin results in decreased expression of LARP1 mRNA | CTD | PMID:29803840 | enzyme inhibitor | multiple interactions | ISO | LARP1 (Homo sapiens) | 6480464 | [Enzyme Inhibitors results in decreased activity of OGA protein] which results in increased O-linked glycosylation of LARP1 protein | CTD | PMID:23301498 | ethanol | affects splicing | EXP | | 6480464 | Ethanol affects the splicing of LARP1 mRNA | CTD | PMID:30319688 | flutamide | increases expression | ISO | Larp1 (Rattus norvegicus) | 6480464 | Flutamide results in increased expression of LARP1 mRNA | CTD | PMID:24136188 | folic acid | increases expression | EXP | | 6480464 | Folic Acid results in increased expression of LARP1 mRNA | CTD | PMID:25629700 | FR900359 | affects phosphorylation | ISO | LARP1 (Homo sapiens) | 6480464 | FR900359 affects the phosphorylation of LARP1 protein | CTD | PMID:37730182 | gentamycin | increases expression | ISO | Larp1 (Rattus norvegicus) | 6480464 | Gentamicins results in increased expression of LARP1 mRNA | CTD | PMID:22061828 | hexadecanoic acid | decreases phosphorylation | ISO | LARP1 (Homo sapiens) | 6480464 | Palmitic Acid results in decreased phosphorylation of LARP1 protein | CTD | PMID:28073184 | indometacin | multiple interactions | ISO | LARP1 (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in decreased expression of LARP1 mRNA | CTD | PMID:28628672 | inulin | multiple interactions | EXP | | 6480464 | [perfluorooctane sulfonic acid co-treated with Inulin] results in decreased expression of LARP1 mRNA | CTD | PMID:36331819 | ivermectin | decreases expression | ISO | LARP1 (Homo sapiens) | 6480464 | Ivermectin results in decreased expression of LARP1 protein | CTD | PMID:32959892 | lead diacetate | increases expression | ISO | Larp1 (Rattus norvegicus) | 6480464 | lead acetate results in increased expression of LARP1 mRNA | CTD | PMID:11578147 | methapyrilene | decreases expression | ISO | Larp1 (Rattus norvegicus) | 6480464 | Methapyrilene results in decreased expression of LARP1 mRNA | CTD | PMID:30467583 | methyl methanesulfonate | decreases expression | ISO | LARP1 (Homo sapiens) | 6480464 | Methyl Methanesulfonate results in decreased expression of LARP1 mRNA | CTD | PMID:23649840 | methylmercury chloride | increases expression | ISO | LARP1 (Homo sapiens) | 6480464 | methylmercuric chloride results in increased expression of LARP1 mRNA | CTD | PMID:26272509 | methylmercury chloride | multiple interactions | ISO | LARP1 (Homo sapiens) | 6480464 | [NOG protein co-treated with methylmercuric chloride co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of LARP1 mRNA | CTD | PMID:27188386 | paracetamol | decreases expression | ISO | LARP1 (Homo sapiens) | 6480464 | Acetaminophen results in decreased expression of LARP1 mRNA | CTD | PMID:21420995 | perfluorooctane-1-sulfonic acid | multiple interactions | EXP | | 6480464 | [perfluorooctane sulfonic acid co-treated with Cellulose] results in decreased expression of LARP1 mRNA more ... | CTD | PMID:36331819 | pirinixic acid | multiple interactions | EXP | | 6480464 | [pirinixic acid binds to and results in increased activity of PPARA protein] which results in increased expression of LARP1 mRNA | CTD | PMID:19710929 | quercetin | increases phosphorylation | ISO | LARP1 (Homo sapiens) | 6480464 | Quercetin results in increased phosphorylation of LARP1 protein | CTD | PMID:35688186 | Salinomycin | decreases expression | ISO | LARP1 (Homo sapiens) | 6480464 | salinomycin results in decreased expression of LARP1 mRNA | CTD | PMID:19682730 | SB 431542 | multiple interactions | ISO | LARP1 (Homo sapiens) | 6480464 | [NOG protein co-treated with methylmercuric chloride co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of LARP1 mRNA | CTD | PMID:27188386 | sirolimus | multiple interactions | ISO | LARP1 (Homo sapiens) | 6480464 | LARP1 protein promotes the reaction [Sirolimus results in decreased expression of RPL32 protein] more ... | CTD | PMID:25940091 | sirolimus | increases response to substance | ISO | LARP1 (Homo sapiens) | 6480464 | LARP1 protein results in increased susceptibility to Sirolimus | CTD | PMID:25940091 | sodium arsenite | decreases expression | ISO | LARP1 (Homo sapiens) | 6480464 | sodium arsenite results in decreased expression of LARP1 protein | CTD | PMID:30528433 | thioacetamide | increases expression | ISO | Larp1 (Rattus norvegicus) | 6480464 | Thioacetamide results in increased expression of LARP1 mRNA | CTD | PMID:34492290 | torin 1 | multiple interactions | ISO | LARP1 (Homo sapiens) | 6480464 | 1-(4-(4-propionylpiperazin-1-yl)-3-(trifluoromethyl)phenyl)-9-(quinolin-3-yl)benzo(h)(1 more ... | CTD | PMID:25940091 | torin 1 | increases response to substance | ISO | LARP1 (Homo sapiens) | 6480464 | LARP1 protein results in increased susceptibility to 1-(4-(4-propionylpiperazin-1-yl)-3-(trifluoromethyl)phenyl)-9-(quinolin-3-yl)benzo(h)(1 and 6)naphthyridin-2(1H)-one | CTD | PMID:25940091 | Tributyltin oxide | decreases phosphorylation | EXP | | 6480464 | bis(tri-n-butyltin)oxide results in decreased phosphorylation of LARP1 protein | CTD | PMID:22174045 | trichostatin A | affects expression | ISO | LARP1 (Homo sapiens) | 6480464 | trichostatin A affects the expression of LARP1 mRNA | CTD | PMID:28542535 | trimellitic anhydride | increases expression | EXP | | 6480464 | trimellitic anhydride results in increased expression of LARP1 mRNA | CTD | PMID:19042947 | triptonide | decreases expression | EXP | | 6480464 | triptonide results in decreased expression of LARP1 mRNA | CTD | PMID:33045310 | troglitazone | decreases expression | EXP | | 6480464 | troglitazone results in decreased expression of LARP1 mRNA | CTD | PMID:28973697 | tungsten | decreases expression | EXP | | 6480464 | Tungsten results in decreased expression of LARP1 mRNA | CTD | PMID:30912803 | valproic acid | affects splicing | ISO | Larp1 (Rattus norvegicus) | 6480464 | Valproic Acid affects the splicing of LARP1 mRNA | CTD | PMID:29427782 | |