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ONTOLOGY REPORT - ANNOTATIONS

Term:positive regulation of epidermal growth factor receptor signaling pathway
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Accession:GO:0045742 term browser browse the term
Definition:Any process that activates or increases the frequency, rate or extent of epidermal growth factor receptor signaling pathway activity.
Synonyms:exact_synonym: positive regulation of EGF receptor signaling pathway;   positive regulation of EGF receptor signalling pathway;   positive regulation of EGFR signaling pathway;   up regulation of epidermal growth factor receptor signaling pathway;   upregulation of epidermal growth factor receptor signaling pathway
 narrow_synonym: activation of epidermal growth factor receptor signaling pathway;   stimulation of epidermal growth factor receptor signaling pathway


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positive regulation of epidermal growth factor receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADAM17 ADAM metallopeptidase domain 17 involved_in
acts_upstream_of		 IEA
ISO		 (PMID:18625725) Ensembl
BHF-UCL		 PMID:18625725 GO_REF:0000107 NCBI chr17:6,589,874...6,638,788
Ensembl chr17:6,589,878...6,638,731 		JBrowse link
G ADRA2A adrenoceptor alpha 2A involved_in IEA Ensembl GO_REF:0000107 NCBI chr28:22,366,989...22,392,163
Ensembl chr28:22,367,780...22,370,684 		JBrowse link
G AFAP1L2 actin filament associated protein 1 like 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr28:25,137,235...25,228,454
Ensembl chr28:25,133,296...25,194,431 		JBrowse link
G AGR2 anterior gradient 2, protein disulphide isomerase family member involved_in IEA Ensembl GO_REF:0000107 NCBI chr14:31,303,784...31,316,752
Ensembl chr14:31,305,567...31,316,686 		JBrowse link
G AGT angiotensinogen involved_in IEA Ensembl GO_REF:0000107 NCBI chr 4:8,681,192...8,694,059
Ensembl chr 4:8,683,798...8,693,880 		JBrowse link
G ARHGEF2 Rho/Rac guanine nucleotide exchange factor 2 involved_in ISO (PMID:23389627) AgBase PMID:23389627 NCBI chr 7:41,835,322...41,850,488
Ensembl chr 7:41,812,353...41,850,488 		JBrowse link
G B9D2 B9 domain containing 2 acts_upstream_of ISO (PMID:18625725) BHF-UCL PMID:18625725 NCBI chr 1:112,621,832...112,627,726
Ensembl chr 1:112,621,633...112,643,885 		JBrowse link
G CCDC88A coiled-coil domain containing 88A involved_in IEA Ensembl GO_REF:0000107 NCBI chr10:56,167,907...56,300,974
Ensembl chr10:56,170,479...56,300,908 		JBrowse link
G CNOT9 CCR4-NOT transcription complex subunit 9 involved_in IEA Ensembl GO_REF:0000107 NCBI chr37:25,186,928...25,213,255
Ensembl chr37:25,187,066...25,212,642 		JBrowse link
G DGKD diacylglycerol kinase delta involved_in IEA Ensembl GO_REF:0000107 NCBI chr25:44,851,827...44,961,352
Ensembl chr25:44,851,493...44,961,364 		JBrowse link
G ESR1 estrogen receptor 1 ISO RGD PMID:17928626 RGD:5128669 NCBI chr 1:42,081,952...42,368,544
Ensembl chr 1:42,081,969...42,368,544 		JBrowse link
G ESR2 estrogen receptor 2 ISO RGD PMID:17928626 RGD:5128669 NCBI chr 8:38,645,917...38,715,347
Ensembl chr 8:38,645,430...38,702,691 		JBrowse link
G FAM83B family with sequence similarity 83 member B involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:22,256,452...22,341,919
Ensembl chr12:22,257,110...22,338,231 		JBrowse link
G FASLG Fas ligand ISO RGD PMID:18471522 RGD:2315731 NCBI chr 7:26,335,837...26,344,224
Ensembl chr 7:26,335,846...26,344,224 		JBrowse link
G GPER1 G protein-coupled estrogen receptor 1 involved_in ISO
IEA		 RGD
Ensembl		 PMID:20445128 GO_REF:0000107 RGD:4892084 NCBI chr 6:15,792,072...15,796,922
Ensembl chr 6:15,792,897...15,794,051 		JBrowse link
G HAP1 huntingtin associated protein 1 involved_in ISO PMID:12890790 UniProt PMID:12890790 RGD:10047165 NCBI chr 9:21,065,770...21,074,462
Ensembl chr 9:21,065,846...21,072,991 		JBrowse link
G HIP1 huntingtin interacting protein 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:6,957,760...7,115,676
Ensembl chr 6:6,961,053...7,115,618 		JBrowse link
G HIP1R huntingtin interacting protein 1 related involved_in IEA Ensembl GO_REF:0000107 NCBI chr26:6,623,583...6,639,107
Ensembl chr26:6,624,791...6,637,659 		JBrowse link
G MIR29A microRNA mir-29a involved_in ISO (PMID:25058496) FlyBase PMID:25058496 NCBI chr14:6,184,844...6,184,903
Ensembl chr14:6,184,830...6,184,916 		JBrowse link
G MMP9 matrix metallopeptidase 9 involved_in IEA Ensembl GO_REF:0000107 NCBI chr24:33,274,260...33,281,116
Ensembl chr24:33,274,268...33,281,293 		JBrowse link
G NEU3 neuraminidase 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr21:23,456,424...23,484,872 JBrowse link
G PDE6G phosphodiesterase 6G involved_in
acts_upstream_of_or_within		 IBA
ISO		 (PMID:11502744) GO_Central
MGI		 PMID:11502744 GO_REF:0000033 NCBI chr 9:525,123...529,406
Ensembl chr 9:526,577...529,526 		JBrowse link
G PDE6H phosphodiesterase 6H acts_upstream_of_or_within ISO (PMID:11502744) MGI PMID:11502744 NCBI chr27:31,640,731...31,664,494
Ensembl chr27:31,640,737...31,664,401 		JBrowse link
G PLAUR plasminogen activator, urokinase receptor involved_in ISO (PMID:22984561) CACAO PMID:22984561 NCBI chr 1:111,476,804...111,490,876
Ensembl chr 1:111,476,893...111,490,880 		JBrowse link
G RALA RAS like proto-oncogene A involved_in IEA Ensembl GO_REF:0000107 NCBI chr18:10,022,490...10,047,583
Ensembl chr18:10,024,311...10,039,183 		JBrowse link
G RALB RAS like proto-oncogene B involved_in IEA Ensembl GO_REF:0000107 NCBI chr19:29,820,006...29,868,345
Ensembl chr19:29,768,359...29,868,335 		JBrowse link
G SHKBP1 SH3KBP1 binding protein 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:113,154,285...113,165,988
Ensembl chr 1:113,154,460...113,165,992 		JBrowse link
G SOS1 SOS Ras/Rac guanine nucleotide exchange factor 1 ISO RGD PMID:8577724 RGD:1581110 NCBI chr17:31,007,940...31,181,569
Ensembl chr17:31,009,257...31,142,063 		JBrowse link
G SPRY2 sprouty RTK signaling antagonist 2 involved_in ISO (PMID:15962011) MGI PMID:15962011 NCBI chr22:33,366,139...33,371,102
Ensembl chr22:33,366,931...33,367,878 		JBrowse link
G TGFB1 transforming growth factor beta 1 acts_upstream_of
involved_in		 ISS
IEA		 UniProt
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr 1:112,629,476...112,643,885
Ensembl chr 1:112,621,633...112,643,885 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 17099
    cellular process 16594
      signal transduction 6024
        positive regulation of signal transduction 1686
          positive regulation of ERBB signaling pathway 32
            positive regulation of epidermal growth factor receptor signaling pathway 30
              positive regulation of epidermal growth factor receptor signaling pathway involved in heart process 0
Path 2
Term Annotations click to browse term
  biological_process 17099
    biological regulation 11803
      regulation of biological process 11452
        regulation of cellular process 11119
          signal transduction 6024
            cell surface receptor signaling pathway 2637
              enzyme-linked receptor protein signaling pathway 986
                cell surface receptor protein tyrosine kinase signaling pathway 605
                  ERBB signaling pathway 139
                    regulation of ERBB signaling pathway 77
                      positive regulation of ERBB signaling pathway 32
                        positive regulation of epidermal growth factor receptor signaling pathway 30
                          positive regulation of epidermal growth factor receptor signaling pathway involved in heart process 0
paths to the root