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ONTOLOGY REPORT - ANNOTATIONS

Term:positive regulation of DNA damage response, signal transduction by p53 class mediator
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Accession:GO:0043517 term browser browse the term
Definition:Any process that activates, maintains or increases the rate of the cascade of processes induced by the cell cycle regulator phosphoprotein p53, or an equivalent protein, in response to the detection of DNA damage.
Synonyms:exact_synonym: positive regulation of p53 induced by DNA damage response;   up regulation of DNA damage response, signal transduction by p53 class mediator;   upregulation of DNA damage response, signal transduction by p53 class mediator
 narrow_synonym: activation of DNA damage response, signal transduction by p53 class mediator;   stimulation of DNA damage response, signal transduction by p53 class mediator


show annotations for term's descendants           Sort by:
positive regulation of DNA damage response, signal transduction by p53 class mediator term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ANKRD1 ankyrin repeat domain 1 involved_in IDA (PMID:20599664) BHF-UCL PMID:20599664 NCBI chr10:90,912,096...90,921,087
Ensembl chr10:90,912,096...90,921,087 		JBrowse link
G ATM ATM serine/threonine kinase involved_in IMP (PMID:9733515) BHF-UCL PMID:9733515 NCBI chr11:108,223,067...108,369,102
Ensembl chr11:108,222,804...108,369,102 		JBrowse link
G ATR ATR serine/threonine kinase involved_in IMP (PMID:9925639) BHF-UCL PMID:9925639 NCBI chr 3:142,449,235...142,578,733
Ensembl chr 3:142,449,007...142,578,733 		JBrowse link
G CDKN2A cyclin dependent kinase inhibitor 2A involved_in IDA (PMID:9529249) BHF-UCL PMID:9529249 NCBI chr 9:21,967,752...21,995,324
Ensembl chr 9:21,967,752...21,995,301 		JBrowse link
G DDX5 DEAD-box helicase 5 involved_in IMP (PMID:15660129) UniProt PMID:15660129 NCBI chr17:64,498,254...64,506,866
Ensembl chr17:64,498,254...64,508,199 		JBrowse link
G EEF1E1 eukaryotic translation elongation factor 1 epsilon 1 involved_in
acts_upstream_of_or_within		 IEA
ISO
ISS		 (PMID:15680327) InterPro
MGI
UniProt
Ensembl		 PMID:15680327 GO_REF:0000002 GO_REF:0000024 GO_REF:0000107 NCBI chr 6:8,073,360...8,102,548
Ensembl chr 6:8,073,360...8,102,559 		JBrowse link
G EEF1E1-BLOC1S5 EEF1E1-BLOC1S5 readthrough (NMD candidate) involved_in IEA InterPro GO_REF:0000002 NCBI chr 6:8,013,567...8,102,595
Ensembl chr 6:8,015,726...8,102,530 		JBrowse link
G EPRS1 glutamyl-prolyl-tRNA synthetase 1 involved_in IEA InterPro GO_REF:0000002 NCBI chr 1:219,968,600...220,046,505
Ensembl chr 1:219,968,600...220,046,530 		JBrowse link
G HIC1 HIC ZBTB transcriptional repressor 1 involved_in ISS
IEA		 UniProt
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr17:2,055,103...2,063,241
Ensembl chr17:2,054,154...2,063,241 		JBrowse link
G MSX1 msh homeobox 1 involved_in IC (PMID:15705871) BHF-UCL PMID:15705871 NCBI chr 4:4,859,665...4,863,936
Ensembl chr 4:4,859,665...4,863,936 		JBrowse link
G PLA2R1 phospholipase A2 receptor 1 involved_in IMP (PMID:19197340) UniProt PMID:19197340 NCBI chr 2:159,923,933...160,062,615
Ensembl chr 2:159,932,006...160,062,615 		JBrowse link
G PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1 involved_in IMP (PMID:15102863) UniProt PMID:15102863 NCBI chr18:59,899,996...59,904,305
Ensembl chr18:59,899,996...59,904,305 		JBrowse link
G SPRED1 sprouty related EVH1 domain containing 1 involved_in ISS
IEA		 (PMID:20736167) BHF-UCL
Ensembl		 PMID:20736167 GO_REF:0000107 NCBI chr15:38,252,836...38,357,249
Ensembl chr15:38,252,836...38,357,249 		JBrowse link
G SPRED2 sprouty related EVH1 domain containing 2 involved_in ISS (PMID:20736167) BHF-UCL PMID:20736167 NCBI chr 2:65,307,175...65,432,599
Ensembl chr 2:65,310,851...65,432,637 		JBrowse link
positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ING4 inhibitor of growth family member 4 involved_in IDA (PMID:15251430) UniProt PMID:15251430 NCBI chr12:6,650,301...6,663,119
Ensembl chr12:6,650,301...6,663,142 		JBrowse link
G PYHIN1 pyrin and HIN domain family member 1 involved_in IDA (PMID:16479015) UniProt PMID:16479015 NCBI chr 1:158,931,552...158,990,870
Ensembl chr 1:158,930,796...158,977,059 		JBrowse link
G RPL26 ribosomal protein L26 involved_in IMP (PMID:16213212) CAFA PMID:16213212 NCBI chr17:8,377,516...8,383,193
Ensembl chr17:8,377,516...8,383,213 		JBrowse link
G ZNF385A zinc finger protein 385A involved_in IMP (PMID:17719541) UniProt PMID:17719541 NCBI chr12:54,369,136...54,391,298
Ensembl chr12:54,369,133...54,391,298 		JBrowse link
G ZNHIT1 zinc finger HIT-type containing 1 involved_in IDA (PMID:17700068) UniProt PMID:17700068 NCBI chr 7:101,218,165...101,224,190
Ensembl chr 7:101,218,165...101,224,190 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19613
    cellular process 18233
      regulation of cellular process 12409
        regulation of cellular response to stress 596
          regulation of DNA damage response, signal transduction by p53 class mediator 42
            positive regulation of DNA damage response, signal transduction by p53 class mediator 19
              positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator 5
Path 2
Term Annotations click to browse term
  biological_process 19613
    biological regulation 13363
      regulation of biological process 12979
        signaling 7170
          signal transduction 6566
            intracellular signal transduction 2993
              signal transduction in response to DNA damage 205
                DNA damage response, signal transduction by p53 class mediator 82
                  regulation of DNA damage response, signal transduction by p53 class mediator 42
                    positive regulation of DNA damage response, signal transduction by p53 class mediator 19
                      positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator 5
paths to the root