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ONTOLOGY REPORT - ANNOTATIONS

Term:DNA damage response, signal transduction by p53 class mediator
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Accession:GO:0030330 term browser browse the term
Definition:A cascade of processes induced by the cell cycle regulator phosphoprotein p53, or an equivalent protein, in response to the detection of DNA damage.
Synonyms:broad_synonym: p53-mediated DNA damage response
 related_synonym: DNA damage response, activation of p53;   TP53 signaling pathway;   p53 signaling pathway
 alt_id: GO:0006976


show annotations for term's descendants           Sort by:
DNA damage response, signal transduction by p53 class mediator term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acer2 alkaline ceramidase 2 involved_in ISO (PMID:28294157), (PMID:29229990) RGD PMID:28294157 PMID:29229990 NCBI chr 5:101,391,830...101,442,615
Ensembl chr 5:101,391,885...101,442,614 		JBrowse link
G Atrx ATRX, chromatin remodeler involved_in ISS
ISO		 GO_REF:0000024
(MGI:5568153|PMID:24651726)		 UniProt
RGD		 PMID:24651726 GO_REF:0000024 MGI:5568153 NCBI chr  X:70,850,981...70,997,330
Ensembl chr  X:70,850,981...70,997,330 		JBrowse link
G Batf basic leucine zipper ATF-like transcription factor involved_in ISS
ISO		 GO_REF:0000024
(MGI:5448499|PMID:22385964)		 UniProt
RGD		 PMID:22385964 GO_REF:0000024 MGI:5448499 NCBI chr 6:105,353,715...105,376,051
Ensembl chr 6:105,353,715...105,376,051 		JBrowse link
G Bcl3 BCL3, transcription coactivator involved_in ISO (PMID:16384933) RGD PMID:16384933 NCBI chr 1:79,471,368...79,485,908
Ensembl chr 1:79,471,369...79,485,607 		JBrowse link
G E2f7 E2F transcription factor 7 involved_in ISO
IEA
ISS		 (PMID:22802528)
GO_REF:0000107
GO_REF:0000024		 RGD
Ensembl
UniProt		 PMID:22802528 GO_REF:0000024 GO_REF:0000107 NCBI chr 7:46,150,533...46,192,739
Ensembl chr 7:46,151,293...46,192,734 		JBrowse link
G Foxo3 forkhead box O3 acts_upstream_of_or_within ISO (MGI:3057054|PMID:15383658) RGD PMID:15383658 MGI:3057054 NCBI chr20:45,669,708...45,764,606
Ensembl chr20:45,672,995...45,764,561 		JBrowse link
G Mdm4 MDM4 regulator of p53 involved_in ISO (PMID:14660608) RGD PMID:14660608 NCBI chr13:44,432,596...44,516,165
Ensembl chr13:44,406,213...44,474,226 		JBrowse link
G Mif macrophage migration inhibitory factor acts_upstream_of_or_within ISO MGI:2673280 (MGI:2670239|PMID:12878730) RGD PMID:12878730 MGI:2670239 NCBI chr20:12,790,919...12,791,784
Ensembl chr20:12,790,902...12,799,504 		JBrowse link
G Myo6 myosin VI involved_in ISO (PMID:16507995) RGD PMID:16507995 NCBI chr 8:81,087,157...81,242,022
Ensembl chr 8:81,087,139...81,239,292 		JBrowse link
G Ndrg1 N-myc downstream regulated 1 involved_in ISO
IEA		 (PMID:9766676)
GO_REF:0000107		 RGD
Ensembl		 PMID:9766676 GO_REF:0000107 NCBI chr 7:98,684,487...98,725,869
Ensembl chr 7:98,684,487...98,725,880 		JBrowse link
G Paxip1 PAX interacting protein 1 involved_in ISO (PMID:15456759), (PMID:17690115) RGD PMID:15456759 PMID:17690115 NCBI chr 4:7,524,887...7,576,663
Ensembl chr 4:7,525,004...7,576,548 		JBrowse link
G Ppm1d protein phosphatase, Mg2+/Mn2+ dependent, 1D acts_upstream_of_or_within ISO (MGI:5013521|PMID:21522133) RGD PMID:21522133 MGI:5013521 NCBI chr10:70,172,603...70,208,607
Ensembl chr10:70,172,603...70,208,607 		JBrowse link
G Sesn2 sestrin 2 involved_in ISO (PMID:18692468)
(MGI:3808916|PMID:18692468)		 RGD PMID:18692468 MGI:3808916 NCBI chr 5:144,702,287...144,721,241
Ensembl chr 5:144,701,530...144,721,260 		JBrowse link
G Tp53 tumor protein p53 involved_in
acts_upstream_of_or_within		 ISO (PMID:15149599), (PMID:20160708)
MGI:106184|MGI:109337 (MGI:2156961|PMID:11790307), (MGI:3032953|PMID:11884608), (MGI:3603875|PMID:16199867), (MGI:3714678|PMID:17476307)		 RGD PMID:11790307 PMID:11884608 PMID:15149599 PMID:16199867 PMID:17476307 More... MGI:2156961 MGI:3032953 MGI:3603875 MGI:3714678 NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524 		JBrowse link
G Triap1 TP53 regulated inhibitor of apoptosis 1 involved_in ISO (PMID:15735003) RGD PMID:15735003 NCBI chr12:41,267,534...41,270,053
Ensembl chr12:41,267,549...41,270,042 		JBrowse link
G Usp10 ubiquitin specific peptidase 10 involved_in IBA
ISS
ISO		 PMID:21873635
GO_REF:0000024
(PMID:20096447)		 UniProt
RGD		 PMID:20096447 PMID:21873635 GO_REF:0000024, RGD:13792537 NCBI chr19:47,972,858...48,014,900
Ensembl chr19:47,972,611...48,014,897 		JBrowse link
DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Casp2 caspase 2 involved_in ISO (PMID:21726810) RGD PMID:21726810 NCBI chr 4:71,149,632...71,167,388
Ensembl chr 4:71,149,669...71,167,379 		JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A involved_in ISO (PMID:15149599) RGD PMID:15149599 NCBI chr20:7,149,177...7,159,727
Ensembl chr20:7,149,217...7,159,585 		JBrowse link
G Cradd CASP2 and RIPK1 domain containing adaptor with death domain involved_in ISO
IBA		 (PMID:21726810)
PMID:21873635		 RGD PMID:21726810 PMID:21873635 RGD:13792537 NCBI chr 7:29,940,240...29,952,907
Ensembl chr 7:29,798,586...29,952,907 		JBrowse link
G Mdm2 MDM2 proto-oncogene involved_in ISO (PMID:21726810) RGD PMID:21726810 NCBI chr 7:53,290,660...53,315,205
Ensembl chr 7:53,290,664...53,314,915 		JBrowse link
G Muc1 mucin 1, cell surface associated involved_in ISO (PMID:15710329) RGD PMID:15710329 NCBI chr 2:174,635,559...174,640,738
Ensembl chr 2:174,635,995...174,640,733 		JBrowse link
G Pcbp4 poly(rC) binding protein 4 involved_in ISO (PMID:10891498) RGD PMID:10891498 NCBI chr 8:107,092,688...107,103,276
Ensembl chr 8:107,093,013...107,103,276 		JBrowse link
G Pidd1 p53-induced death domain protein 1 involved_in ISO (PMID:21726810) RGD PMID:21726810 NCBI chr 1:196,536,815...196,542,808
Ensembl chr 1:196,536,834...196,542,699 		JBrowse link
G Pml PML nuclear body scaffold involved_in ISO (MGI:3580934|PMID:15626733) RGD PMID:15626733 MGI:3580934 NCBI chr 8:58,627,347...58,661,927
Ensembl chr 8:58,628,837...58,658,971 		JBrowse link
G Ppp2r5c protein phosphatase 2, regulatory subunit B', gamma involved_in ISO (PMID:17245430) RGD PMID:17245430 NCBI chr 6:129,461,689...129,598,344
Ensembl chr 6:129,461,648...129,598,346 		JBrowse link
G Prap1 proline-rich acidic protein 1 involved_in ISS
ISO		 GO_REF:0000024
(PMID:23235459)		 UniProt
RGD		 PMID:23235459 GO_REF:0000024 NCBI chr 1:194,883,078...194,886,874
Ensembl chr 1:194,883,078...194,886,872 		JBrowse link
G Rbm38 RNA binding motif protein 38 involved_in ISO (PMID:17050675) RGD PMID:17050675 NCBI chr 3:161,801,550...161,814,381
Ensembl chr 3:161,801,577...161,814,381 		JBrowse link
G Rpl26 ribosomal protein L26 involved_in ISO (PMID:16213212)
(MGI:5882892|PMID:16213212)		 RGD PMID:16213212 MGI:5882892 NCBI chr10:53,610,836...53,613,966
Ensembl chr10:53,610,421...53,613,966 		JBrowse link
G Tp53 tumor protein p53 involved_in
acts_upstream_of_or_within		 ISO (PMID:16213212)
MGI:108027 (MGI:3589512|PMID:16107883)		 RGD PMID:16107883 PMID:16213212 MGI:3589512 NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524 		JBrowse link
DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Brca2 BRCA2, DNA repair associated involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:1930616 (MGI:84760|PMID:8738145)		 Ensembl
RGD		 PMID:8738145 GO_REF:0000107 MGI:84760 NCBI chr12:59,492...103,789
Ensembl chr12:59,819...100,567 		JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A acts_upstream_of_or_within ISO (MGI:1354114|PMID:10710310) RGD PMID:10710310 MGI:1354114 NCBI chr20:7,149,177...7,159,727
Ensembl chr20:7,149,217...7,159,585 		JBrowse link
G Chek2 checkpoint kinase 2 acts_upstream_of_or_within ISO MGI:2386905 (MGI:1354114|PMID:10710310) RGD PMID:10710310 MGI:1354114 NCBI chr12:45,788,823...45,821,382
Ensembl chr12:45,788,827...45,821,286 		JBrowse link
G Foxm1 forkhead box M1 involved_in ISO
IEA		 (PMID:17101782)
GO_REF:0000107
(MGI:3698692|PMID:17101782)		 RGD
Ensembl		 PMID:17101782 GO_REF:0000107 MGI:3698692 NCBI chr 4:161,639,561...161,652,012
Ensembl chr 4:161,638,816...161,650,684 		JBrowse link
G Hipk2 homeodomain interacting protein kinase 2 involved_in ISO (PMID:14647468) RGD PMID:14647468 NCBI chr 4:67,439,327...67,619,223
Ensembl chr 4:67,440,501...67,619,223 		JBrowse link
G Kat5 lysine acetyltransferase 5 involved_in ISS
ISO		 GO_REF:0000024
(PMID:14966270)		 UniProt
RGD		 PMID:14966270 GO_REF:0000024 NCBI chr 1:202,895,751...202,903,178
Ensembl chr 1:202,895,751...202,903,458 		JBrowse link
G Muc1 mucin 1, cell surface associated involved_in ISO (PMID:15710329) RGD PMID:15710329 NCBI chr 2:174,635,559...174,640,738
Ensembl chr 2:174,635,995...174,640,733 		JBrowse link
G Rbm38 RNA binding motif protein 38 involved_in ISO (PMID:17050675) RGD PMID:17050675 NCBI chr 3:161,801,550...161,814,381
Ensembl chr 3:161,801,577...161,814,381 		JBrowse link
G Rps27l ribosomal protein S27-like involved_in ISO (PMID:18056458) RGD PMID:18056458 NCBI chr 8:67,562,483...67,567,418
Ensembl chr 8:67,562,483...67,567,418 		JBrowse link
G Rps6ka6 ribosomal protein S6 kinase A6 involved_in IBA
ISO		 PMID:21873635
(PMID:15042092)		 RGD PMID:15042092 PMID:21873635 RGD:13792537 NCBI chr  X:76,354,824...76,454,484
Ensembl chr  X:76,353,760...76,454,484 		JBrowse link
G Sp100 SP100 nuclear antigen involved_in ISO (PMID:14647468) RGD PMID:14647468 NCBI chr 9:86,310,990...86,377,036
Ensembl chr 9:86,311,032...86,377,034 		JBrowse link
G Tfap4 transcription factor AP-4 involved_in ISO (PMID:18818310) RGD PMID:18818310 NCBI chr10:11,001,338...11,019,386
Ensembl chr10:11,002,911...11,019,386 		JBrowse link
G Tp53 tumor protein p53 involved_in
acts_upstream_of_or_within		 ISO (PMID:16213212), (PMID:16479015), (PMID:7958916)
(MGI:1354114|PMID:10710310)		 RGD PMID:7958916 PMID:10710310 PMID:16213212 PMID:16479015 MGI:1354114 NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524 		JBrowse link
negative regulation of DNA damage response, signal transduction by p53 class mediator term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd44 CD44 molecule (Indian blood group) involved_in ISO (PMID:17045821)
(MGI:3690285|PMID:17045821)		 RGD PMID:17045821 MGI:3690285 NCBI chr 3:89,155,850...89,244,615
Ensembl chr 3:89,157,058...89,244,620 		JBrowse link
G Cd74 CD74 molecule involved_in ISS
ISO
IBA		 GO_REF:0000024
(MGI:3690285|PMID:17045821)
(PMID:17045821)
PMID:21873635		 BHF-UCL
RGD		 PMID:17045821 PMID:21873635 GO_REF:0000024 MGI:3690285, RGD:13792537 NCBI chr18:54,256,757...54,266,003
Ensembl chr18:54,256,778...54,266,003 		JBrowse link
G Dyrk1a dual specificity tyrosine phosphorylation regulated kinase 1A involved_in ISO (MGI:5318016|PMID:20736167) RGD PMID:20736167 MGI:5318016 NCBI chr11:33,890,706...34,009,420
Ensembl chr11:33,890,490...34,009,420 		JBrowse link
G Dyrk3 dual specificity tyrosine phosphorylation regulated kinase 3 involved_in IEA
ISO		 GO_REF:0000107
(MGI:4838949|PMID:20167603)		 Ensembl
RGD		 PMID:20167603 GO_REF:0000107 MGI:4838949 NCBI chr13:42,594,120...42,604,898
Ensembl chr13:42,594,121...42,604,778 		JBrowse link
G Kdm1a lysine demethylase 1A involved_in ISO (PMID:17805299) RGD PMID:17805299 NCBI chr 5:148,782,976...148,838,319
Ensembl chr 5:148,782,976...148,838,319 		JBrowse link
G Marchf7 membrane associated ring-CH-type finger 7 involved_in ISO
ISS		 (PMID:29295817)
GO_REF:0000024		 RGD
UniProt		 PMID:29295817 GO_REF:0000024 NCBI chr 3:44,680,229...44,720,172
Ensembl chr 3:44,681,632...44,720,168 		JBrowse link
G Mdm2 MDM2 proto-oncogene involved_in ISO (PMID:10360174), (PMID:9529249) RGD PMID:9529249 PMID:10360174 NCBI chr 7:53,290,660...53,315,205
Ensembl chr 7:53,290,664...53,314,915 		JBrowse link
G Mif macrophage migration inhibitory factor involved_in ISO (PMID:17045821)
(MGI:3690285|PMID:17045821)		 RGD PMID:17045821 MGI:3690285 NCBI chr20:12,790,919...12,791,784
Ensembl chr20:12,790,902...12,799,504 		JBrowse link
G Psmd10 proteasome 26S subunit, non-ATPase 10 involved_in ISS
ISO		 GO_REF:0000024
(PMID:16023600)		 UniProt
RGD		 PMID:16023600 GO_REF:0000024 NCBI chr  X:104,656,809...104,665,126
Ensembl chr  X:104,656,812...104,665,097 		JBrowse link
G Pttg1ip PTTG1 interacting protein acts_upstream_of_or_within ISO (PMID:24506068) RGD PMID:24506068 NCBI chr20:11,030,013...11,047,742
Ensembl chr20:11,030,015...11,047,316 		JBrowse link
G Senp2 SUMO specific peptidase 2 acts_upstream_of_or_within ISO (MGI:5433829|PMID:21183956) RGD PMID:21183956 MGI:5433829 NCBI chr11:78,981,429...79,018,274
Ensembl chr11:78,981,432...79,018,238 		JBrowse link
G Sirt1 sirtuin 1 involved_in ISO (PMID:11672523) RGD PMID:11672523 NCBI chr20:25,307,143...25,329,260
Ensembl chr20:25,306,917...25,329,260 		JBrowse link
G Snai1 snail family transcriptional repressor 1 involved_in ISO (PMID:15314165) RGD PMID:15314165 NCBI chr 3:156,248,479...156,252,969
Ensembl chr 3:156,248,485...156,252,969 		JBrowse link
G Snai2 snail family transcriptional repressor 2 involved_in ISO (PMID:15314165) RGD PMID:15314165 NCBI chr11:86,183,800...86,186,109
Ensembl chr11:86,181,909...86,186,200 		JBrowse link
G Twist1 twist family bHLH transcription factor 1 involved_in ISO (PMID:17690110) RGD PMID:17690110 NCBI chr 6:50,674,910...50,676,904
Ensembl chr 6:50,674,678...50,677,653 		JBrowse link
negative regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pcbp4 poly(rC) binding protein 4 acts_upstream_of_or_within ISO (MGI:5050389|PMID:20817677) RGD PMID:20817677 MGI:5050389 NCBI chr 8:107,092,688...107,103,276
Ensembl chr 8:107,093,013...107,103,276 		JBrowse link
positive regulation of DNA damage response, signal transduction by p53 class mediator term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ankrd1 ankyrin repeat domain 1 involved_in ISO (PMID:20599664) RGD PMID:20599664 NCBI chr 1:233,815,851...233,834,891
Ensembl chr 1:233,815,851...233,834,919 		JBrowse link
G Atm ATM serine/threonine kinase involved_in ISO (PMID:9733515) RGD PMID:9733515 NCBI chr 8:53,828,741...53,932,773
Ensembl chr 8:53,831,093...53,932,437 		JBrowse link
G Atr ATR serine/threonine kinase involved_in ISO (PMID:9925639) RGD PMID:9925639 NCBI chr 8:96,426,704...96,524,152
Ensembl chr 8:96,426,724...96,524,136 		JBrowse link
G Cdkn2a cyclin-dependent kinase inhibitor 2A involved_in ISO (PMID:9529249) RGD PMID:9529249 NCBI chr 5:103,984,949...103,992,143
Ensembl chr 5:103,984,949...104,003,149 		JBrowse link
G Ddx5 DEAD-box helicase 5 involved_in ISO (PMID:15660129) RGD PMID:15660129 NCBI chr10:91,723,508...91,732,210
Ensembl chr10:91,723,508...91,732,283 		JBrowse link
G Eef1e1 eukaryotic translation elongation factor 1 epsilon 1 acts_upstream_of_or_within ISO MGI:3574590 (MGI:3573962|PMID:15680327) RGD PMID:15680327 MGI:3573962 NCBI chr17:26,148,652...26,159,358
Ensembl chr17:26,148,633...26,215,720 		JBrowse link
G Hic1 HIC ZBTB transcriptional repressor 1 involved_in ISO (MGI:5297787|PMID:16269335) RGD PMID:16269335 MGI:5297787 NCBI chr10:60,014,520...60,019,475
Ensembl chr10:60,011,528...60,019,475 		JBrowse link
G Pla2r1 phospholipase A2 receptor 1 involved_in ISS
ISO		 GO_REF:0000024
(PMID:19197340)		 UniProt
RGD		 PMID:19197340 GO_REF:0000024 NCBI chr 3:44,883,943...45,013,793
Ensembl chr 3:44,883,943...45,013,660 		JBrowse link
G Pmaip1 phorbol-12-myristate-13-acetate-induced protein 1 involved_in ISO (PMID:15102863)
(MGI:2679929|PMID:14500851)		 RGD PMID:14500851 PMID:15102863 MGI:2679929 NCBI chr18:59,986,187...59,990,174
Ensembl chr18:59,986,017...59,992,429 		JBrowse link
G Spred1 sprouty-related, EVH1 domain containing 1 involved_in ISO (MGI:5318016|PMID:20736167) RGD PMID:20736167 MGI:5318016 NCBI chr 3:103,983,120...104,050,321
Ensembl chr 3:103,983,072...104,049,718 		JBrowse link
G Spred2 sprouty-related, EVH1 domain containing 2 involved_in ISO (MGI:5318016|PMID:20736167) RGD PMID:20736167 MGI:5318016 NCBI chr14:94,226,312...94,248,162
Ensembl chr14:94,148,837...94,249,162 		JBrowse link
positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ing4 inhibitor of growth family, member 4 involved_in ISO (PMID:15251430) RGD PMID:15251430 NCBI chr 4:157,841,882...157,850,519
Ensembl chr 4:157,841,951...157,850,265 		JBrowse link
G Rpl26 ribosomal protein L26 involved_in ISO (PMID:16213212) RGD PMID:16213212 NCBI chr10:53,610,836...53,613,966
Ensembl chr10:53,610,421...53,613,966 		JBrowse link
G Zfp385a zinc finger protein 385A involved_in ISO (PMID:17719541) RGD PMID:17719541 NCBI chr 7:134,448,914...134,475,548
Ensembl chr 7:134,448,921...134,475,548 		JBrowse link
G Znhit1 zinc finger, HIT-type containing 1 involved_in ISO (PMID:17700068) RGD PMID:17700068 NCBI chr12:19,686,606...19,692,880
Ensembl chr12:19,686,148...19,692,880 		JBrowse link
regulation of DNA damage response, signal transduction by p53 class mediator term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AABR07010705.1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 Ensembl chr 2:142,289,467...142,290,623 JBrowse link
G AABR07033047.1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 Ensembl chr11:3,479,411...3,480,543 JBrowse link
G Kmt5a lysine methyltransferase 5A involved_in ISO
IBA		 (PMID:17707234)
PMID:21873635		 RGD PMID:17707234 PMID:21873635 RGD:13792537 NCBI chr12:32,139,353...32,167,777
Ensembl chr12:32,139,178...32,162,711 		JBrowse link
G Npm1 nucleophosmin 1 acts_upstream_of_or_within ISO MGI:98834 (MGI:3603875|PMID:16199867) RGD PMID:16199867 MGI:3603875 NCBI chr10:17,741,512...17,751,626
Ensembl chr10:17,739,941...17,751,645 		JBrowse link
G RGD1561318 similar to SET domain-containing protein involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr  X:92,178,344...92,180,517
Ensembl chr  X:92,178,016...92,179,731 		JBrowse link
G Smyd2 SET and MYND domain containing 2 involved_in ISO
ISS		 (PMID:17108971)
GO_REF:0000024		 RGD
UniProt		 PMID:17108971 GO_REF:0000024 NCBI chr13:101,425,270...101,466,576
Ensembl chr13:101,425,273...101,466,576 		JBrowse link
G Sox4 SRY-box transcription factor 4 involved_in ISO (PMID:19234109) RGD PMID:19234109 NCBI chr17:35,667,809...35,672,515
Ensembl chr17:35,667,537...35,673,665 		JBrowse link
G Tp53 tumor protein p53 acts_upstream_of_or_within ISO MGI:1890508 (MGI:5013521|PMID:21522133) RGD PMID:21522133 MGI:5013521 NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524 		JBrowse link
G Zmpste24 zinc metallopeptidase STE24 acts_upstream_of_or_within ISO MGI:2180033|MGI:98834 (MGI:3789238|PMID:16079796), (MGI:5013521|PMID:21522133) RGD PMID:16079796 PMID:21522133 MGI:3789238 MGI:5013521 NCBI chr 5:134,627,218...134,660,360
Ensembl chr 5:134,627,229...134,660,110 		JBrowse link
regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cops3 COP9 signalosome subunit 3 involved_in ISO (PMID:15861129) RGD PMID:15861129 NCBI chr10:44,618,115...44,652,807
Ensembl chr10:44,618,115...44,641,597 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19738
    cellular process 17330
      signal transduction 7035
        intracellular signal transduction 2720
          signal transduction by p53 class mediator 158
            DNA damage response, signal transduction by p53 class mediator 73
              DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest 13
              DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator + 19
              negative regulation of DNA damage response, signal transduction by p53 class mediator + 16
              positive regulation of DNA damage response, signal transduction by p53 class mediator + 15
              regulation of DNA damage response, signal transduction by p53 class mediator + 41
Path 2
Term Annotations click to browse term
  biological_process 19738
    biological regulation 13436
      regulation of biological process 13021
        regulation of cellular process 11037
          signal transduction 7035
            intracellular signal transduction 2720
              signal transduction by p53 class mediator 158
                DNA damage response, signal transduction by p53 class mediator 73
                  DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest 13
                  DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator + 19
                  negative regulation of DNA damage response, signal transduction by p53 class mediator + 16
                  positive regulation of DNA damage response, signal transduction by p53 class mediator + 15
                  regulation of DNA damage response, signal transduction by p53 class mediator + 41
paths to the root