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ONTOLOGY REPORT - ANNOTATIONS

Term:positive regulation of mast cell degranulation
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Accession:GO:0043306 term browser browse the term
Definition:Any process that activates or increases the frequency, rate or extent of mast cell degranulation.
Synonyms:exact_synonym: positive regulation of mast cell granule exocytosis;   up regulation of mast cell degranulation;   upregulation of mast cell degranulation
 narrow_synonym: activation of mast cell degranulation;   stimulation of mast cell degranulation

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positive regulation of mast cell degranulation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adora2b adenosine A2b receptor acts_upstream_of_or_within ISO (PMID:11454903) MGI PMID:11454903 NCBI chrNW_004624877:4,421,307...4,447,574
Ensembl chrNW_004624877:4,422,022...4,447,460 		JBrowse link
G Adora3 adenosine A3 receptor acts_upstream_of_or_within ISO (PMID:12817016) MGI PMID:12817016 NCBI chrNW_004624772:7,189,381...7,232,919
Ensembl chrNW_004624772:7,229,093...7,232,837 		JBrowse link
G Crhr1 corticotropin releasing hormone receptor 1 ISO RGD PMID:18209484 RGD:5130941 NCBI chrNW_004624849:2,484,144...2,528,130
Ensembl chrNW_004624849:2,484,109...2,528,223 		JBrowse link
G Fcer1a Fc fragment of IgE receptor Ia acts_upstream_of_or_within ISO (PMID:9000133) MGI PMID:9000133 NCBI chrNW_004624794:2,003,031...2,008,930
Ensembl chrNW_004624794:2,002,928...2,008,940 		JBrowse link
G Fcer1g Fc fragment of IgE receptor Ig acts_upstream_of_or_within ISO (PMID:14764707) MGI PMID:14764707 NCBI chrNW_004624794:168,564...172,433
Ensembl chrNW_004624794:168,564...172,034 		JBrowse link
G Fgr FGR proto-oncogene, Src family tyrosine kinase involved_in ISO (MGI:5294498|PMID:21746961) UniProt PMID:21746961 MGI:5294498 NCBI chrNW_004624764:11,482,719...11,513,215
Ensembl chrNW_004624764:11,489,685...11,513,270 		JBrowse link
G Gab2 GRB2 associated binding protein 2 involved_in ISO (MGI:2137187|PMID:11449275) UniProt PMID:11449275 MGI:2137187 NCBI chrNW_004624863:1,216,664...1,410,934
Ensembl chrNW_004624863:1,219,866...1,281,847 		JBrowse link
G Gata1 GATA binding protein 1 ISO RGD PMID:22390417 RGD:9587812 NCBI chrNW_004624893:595,948...602,980
Ensembl chrNW_004624893:595,967...602,979 		JBrowse link
G Gata2 GATA binding protein 2 ISO RGD PMID:22390417 RGD:9587812 NCBI chrNW_004624961:147,685...155,614
Ensembl chrNW_004624961:143,358...154,003 		JBrowse link
G Il13 interleukin 13 acts_upstream_of_or_within ISO (PMID:15944273) MGI PMID:15944273 NCBI chrNW_004624733:39,427,189...39,430,019
Ensembl chrNW_004624733:39,428,095...39,429,843 		JBrowse link
G Il4 interleukin 4 acts_upstream_of_or_within ISO (PMID:15944273) MGI PMID:15944273 NCBI chrNW_004624733:39,412,800...39,420,079 JBrowse link
G Il4r interleukin 4 receptor acts_upstream_of_or_within ISO (PMID:15944273) MGI PMID:15944273 NCBI chrNW_004624782:11,981,781...12,008,362 JBrowse link
G Ms4a2 membrane spanning 4-domains A2 ISO RGD PMID:16177098 RGD:1578516 NCBI chrNW_004624864:804,950...813,419
Ensembl chrNW_004624864:807,253...813,381 		JBrowse link
G Nppc natriuretic peptide C involved_in ISO PMID:9663691 UniProt PMID:9663691 RGD:13461752 NCBI chrNW_004624843:4,869,278...4,873,444
Ensembl chrNW_004624843:4,869,614...4,873,448 		JBrowse link
G Pld2 phospholipase D2 ISO RGD PMID:16861349 RGD:2299903 NCBI chrNW_004624786:8,690,968...8,702,213
Ensembl chrNW_004624786:8,690,461...8,702,771 		JBrowse link
G Sphk2 sphingosine kinase 2 involved_in ISO (MGI:3703830|PMID:17346996) UniProt PMID:17346996 MGI:3703830 NCBI chrNW_004624832:5,246,328...5,254,247
Ensembl chrNW_004624832:5,246,895...5,253,207 		JBrowse link
G Stxbp1 syntaxin binding protein 1 ISO RGD PMID:23487749 RGD:12904029 NCBI chrNW_004624760:7,843,741...7,914,444
Ensembl chrNW_004624760:7,842,640...7,914,484 		JBrowse link
G Stxbp2 syntaxin binding protein 2 ISO RGD PMID:23487749 RGD:12904029 NCBI chrNW_004624828:718,728...725,063
Ensembl chrNW_004624828:718,485...725,483 		JBrowse link
G Syk spleen associated tyrosine kinase acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:9000133) MGI
Ensembl
TreeGrafter
RGD		 PMID:9000133 PMID:16861349 GO_REF:0000107 GO_REF:0000118 RGD:2299903 NCBI chrNW_004624868:1,654,079...1,738,648
Ensembl chrNW_004624868:1,653,997...1,701,391 		JBrowse link
positive regulation of histamine secretion by mast cell term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nppa natriuretic peptide A involved_in ISO PMID:9663691 UniProt PMID:9663691 RGD:13461752 NCBI chrNW_004624818:1,147,654...1,149,722
Ensembl chrNW_004624818:1,147,974...1,148,927 		JBrowse link
G Pla2g3 phospholipase A2 group III involved_in ISO (MGI:5492190|PMID:23624557)
(PMID:23624557)		 UniProt PMID:23624557 MGI:5492190 NCBI chrNW_004624747:7,602,848...7,607,872
Ensembl chrNW_004624747:7,603,277...7,607,753 		JBrowse link
G Snx4 sorting nexin 4 involved_in ISO (PMID:18253931) UniProt PMID:18253931 NCBI chrNW_004624731:1,522,467...1,585,793
Ensembl chrNW_004624731:1,522,098...1,586,066 		JBrowse link
G Vamp7 vesicle associated membrane protein 7 involved_in ISO (PMID:18253931) UniProt PMID:18253931 NCBI chrNW_004624980:40,937...94,547
Ensembl chrNW_004624980:40,843...94,528 		JBrowse link
G Vamp8 vesicle associated membrane protein 8 involved_in ISO (PMID:18253931) UniProt PMID:18253931 NCBI chrNW_004624749:17,558,429...17,562,765
Ensembl chrNW_004624749:17,558,429...17,562,723 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 15093
    immune system process 2103
      immune effector process 553
        positive regulation of immune effector process 234
          positive regulation of leukocyte degranulation 32
            positive regulation of mast cell degranulation 24
              positive regulation of histamine secretion by mast cell 5
              positive regulation of mast cell degranulation in another organism 0
Path 2
Term Annotations click to browse term
  biological_process 15093
    localization 4970
      establishment of localization 4307
        transport 4014
          secretion 1066
            secretion by cell 923
              exocytosis 360
                regulated exocytosis 251
                  leukocyte degranulation 80
                    regulation of leukocyte degranulation 51
                      positive regulation of leukocyte degranulation 32
                        positive regulation of mast cell degranulation 24
                          positive regulation of histamine secretion by mast cell 5
                          positive regulation of mast cell degranulation in another organism 0
paths to the root