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ONTOLOGY REPORT - ANNOTATIONS

Term:3'-5' DNA helicase activity
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Accession:GO:0043138 term browser browse the term
Definition:Unwinding a DNA helix in the direction 5' to 3', driven by ATP hydrolysis.
Synonyms:exact_synonym: 3' to 5' DNA helicase activity;   ATP-dependent 3' to 5' DNA helicase activity;   ATP-dependent 3'-5' DNA helicase activity
 alt_id: GO:0043140
 xref: EC:5.6.2.4;   Reactome:R-HSA-167097 "HIV Promoter Opening: First Transition";   Reactome:R-HSA-174438 "Formation of the Flap Intermediate on the C-strand";   Reactome:R-HSA-75949 "RNA Polymerase II Promoter Opening: First Transition";   Reactome:R-HSA-9613490 "Unwinding of DNA for the nascent HIV-1 transcript: Second Transition";   Reactome:R-HSA-9613494 "Unwinding of DNA for the Nascent Transcript: Second Transition";   Reactome:R-HSA-9613497 "Unwinding DNA for the nascent transcript";   Reactome:R-HSA-9613498 "Unwinding of DNA for the nascent HIV-1 transcript";   Reactome:R-HSA-9684118 "ERCC3-facilitated RNA Pol II backtracking in TC-NER"


show annotations for term's descendants           Sort by:
3'-5' DNA helicase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ascc3 activating signal cointegrator 1 complex subunit 3 enables ISO
ISS
IBA		 (PMID:22055184)
GO_REF:0000024
GO_REF:0000033		 RGD
UniProt
GO_Central		 PMID:22055184 GO_REF:0000024 GO_REF:0000033 NCBI chr20:53,510,137...53,795,446
Ensembl chr20:53,510,184...53,790,165 		JBrowse link
G Blm BLM RecQ like helicase enables IBA
ISO		 GO_REF:0000033
(PMID:9840919)		 GO_Central
RGD		 PMID:9840919 GO_REF:0000033 NCBI chr 1:134,409,832...134,496,073
Ensembl chr 1:134,409,857...134,484,312 		JBrowse link
G Dhx9 DExH-box helicase 9 enables ISO
IBA		 (PMID:21561811)
GO_REF:0000033		 RGD
GO_Central		 PMID:21561811 GO_REF:0000033 NCBI chr13:65,602,322...65,639,098
Ensembl chr13:65,602,323...65,639,069 		JBrowse link
G Ercc3 ERCC excision repair 3, TFIIH core complex helicase subunit enables ISO
IBA		 (PMID:17466626), (PMID:8663148)
GO_REF:0000033		 RGD
GO_Central		 PMID:8663148 PMID:17466626 GO_REF:0000033 NCBI chr18:23,883,613...23,914,326
Ensembl chr18:23,883,580...23,914,329 		JBrowse link
G Fancm FA complementation group M enables IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 6:83,126,903...83,180,455
Ensembl chr 6:83,127,093...83,180,028 		JBrowse link
G Fbh1 F-box DNA helicase 1 enables ISO
IBA		 (PMID:11956208), (PMID:23393192)
GO_REF:0000033		 RGD
GO_Central		 PMID:11956208 PMID:23393192 GO_REF:0000033 NCBI chr17:66,749,506...66,787,590
Ensembl chr17:66,749,534...66,787,590 		JBrowse link
G Mcm2 minichromosome maintenance complex component 2 contributes_to IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 4:121,346,434...121,360,962
Ensembl chr 4:121,346,434...121,360,847 		JBrowse link
G Mcm5 minichromosome maintenance complex component 5 contributes_to IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr19:13,483,030...13,504,389
Ensembl chr19:13,483,066...13,504,389 		JBrowse link
G Nav2 neuron navigator 2 enables ISO (PMID:12214280) RGD PMID:12214280 NCBI chr 1:98,957,629...99,322,339
Ensembl chr 1:98,663,759...99,322,337 		JBrowse link
G Recql RecQ like helicase enables ISS
IBA
ISO
IEA		 GO_REF:0000024
GO_REF:0000033
(PMID:35025765), (PMID:8056767)
GO_REF:0000107		 UniProt
GO_Central
RGD
Ensembl		 PMID:8056767 PMID:35025765 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 NCBI chr 4:175,308,337...175,332,965
Ensembl chr 4:175,304,117...175,332,945 		JBrowse link
G Recql4 RecQ like helicase 4 NOT|enables ISO
IBA		 (PMID:19177149)
GO_REF:0000033		 RGD
GO_Central		 PMID:19177149 GO_REF:0000033 NCBI chr 7:108,423,453...108,430,790
Ensembl chr 7:108,423,455...108,430,619 		JBrowse link
G Recql5 RecQ like helicase 5 enables IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr10:101,126,544...101,165,739
Ensembl chr10:101,126,547...101,165,652 		JBrowse link
G Ruvbl1 RuvB-like AAA ATPase 1 IDA RGD PMID:10336418 RGD:729809 NCBI chr 4:120,932,486...120,967,400
Ensembl chr 4:120,932,417...121,029,384 		JBrowse link
G Wrn WRN RecQ like helicase enables ISO
IBA		 (PMID:17715146)
GO_REF:0000033		 RGD
GO_Central		 PMID:17715146 GO_REF:0000033 NCBI chr16:58,763,517...58,898,604
Ensembl chr16:58,763,504...58,895,450 		JBrowse link
single-stranded 3'-5' DNA helicase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dhx9 DExH-box helicase 9 enables ISO (PMID:20669935), (PMID:24049074) RGD PMID:20669935 PMID:24049074 NCBI chr13:65,602,322...65,639,098
Ensembl chr13:65,602,323...65,639,069 		JBrowse link
G Helq helicase, POLQ-like enables ISO (PMID:11751861), (PMID:34316696), (PMID:34937945) RGD PMID:11751861 PMID:34316696 PMID:34937945 NCBI chr14:8,818,582...8,862,926
Ensembl chr14:8,818,592...8,862,960 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  molecular_function 20487
    ATP-dependent activity 627
      helicase activity 153
        DNA helicase activity 64
          3'-5' DNA helicase activity 15
            single-stranded 3'-5' DNA helicase activity 2
Path 2
Term Annotations click to browse term
  molecular_function 20487
    catalytic activity 6037
      catalytic activity, acting on a nucleic acid 630
        catalytic activity, acting on DNA 254
          ATP-dependent activity, acting on DNA 126
            DNA helicase activity 64
              3'-5' DNA helicase activity 15
                single-stranded 3'-5' DNA helicase activity 2
paths to the root