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ONTOLOGY REPORT - ANNOTATIONS

Term:benzene-containing compound metabolic process
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Accession:GO:0042537 term browser browse the term
Definition:The chemical reactions and pathways involving benzene, C6H6, a volatile, very inflammable liquid, contained in the naphtha produced by the destructive distillation of coal, from which it is separated by fractional distillation, or any of its derivatives.
Synonyms:exact_synonym: benzene and derivative metabolic process;   benzene and derivative metabolism;   benzene-containing compound metabolism


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benzene-containing compound metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CYP1B1 cytochrome P450 family 1 subfamily B member 1 acts_upstream_of_or_within
involved_in		 ISO
IEA		 benzo[a]pyrene
(PMID:10051580)
(PMID:1910294)
(PMID:9367523), (PMID:9377560)		 RGD
MGI
Ensembl		 PMID:1910294 PMID:9367523 PMID:9377560 PMID:9806168 PMID:10051580 More... GO_REF:0000107 RGD:7800739 RGD:7829724 NCBI chr17:30,273,281...30,278,554
Ensembl chr17:30,272,749...30,278,554 		JBrowse link
G TXNRD1 thioredoxin reductase 1 ISO 5,5'-dithiobis-(2-nitrobenzoic acid) (DTNB) RGD PMID:20345183 RGD:5133728 NCBI chr10:33,904,065...34,021,549
Ensembl chr10:33,886,343...34,021,696 		JBrowse link
4-chlorobiphenyl metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G UGT1A6 UDP glucuronosyltransferase 1 family, polypeptide A6 ISO RGD PMID:16006569 RGD:1600442 NCBI chr25:45,081,655...45,161,584
Ensembl chr25:45,032,130...45,160,941 		JBrowse link
anthranilate metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G HAAO 3-hydroxyanthranilate 3,4-dioxygenase involved_in IEA UniProt GO_REF:0000104 NCBI chr10:45,368,157...45,379,521
Ensembl chr10:45,368,178...45,379,160 		JBrowse link
G KMO kynurenine 3-monooxygenase involved_in IEA UniProt GO_REF:0000104 NCBI chr 7:32,941,487...32,994,541
Ensembl chr 7:32,941,487...32,994,541 		JBrowse link
G KYNU kynureninase involved_in IEA
IBA		 UniProt
GO_Central
Ensembl		 GO_REF:0000033 GO_REF:0000104 GO_REF:0000107 NCBI chr19:45,022,450...45,150,977
Ensembl chr19:45,022,072...45,149,339 		JBrowse link
biphenyl catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G LOC480777 UDP-glucuronosyltransferase 2A1 ISO RGD PMID:16006569 RGD:1600442 NCBI chr13:58,911,301...58,932,594
Ensembl chr13:59,138,348...59,222,802
Ensembl chr13:59,138,348...59,222,802 		JBrowse link
biphenyl metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CYP11A1 cytochrome P450 family 11 subfamily A member 1 ISO PCB126
Aroclor 1254		 RGD PMID:19071209 PMID:20356859 RGD:4448154 RGD:4768197 NCBI chr30:37,474,997...37,487,028
Ensembl chr30:37,473,901...37,487,507 		JBrowse link
G CYP17A1 cytochrome P450 family 17 subfamily A member 1 ISO PCB126 RGD PMID:20356859 RGD:4448154 NCBI chr28:15,292,959...15,298,896
Ensembl chr28:15,293,106...15,298,852 		JBrowse link
G CYP19A1 cytochrome P450 family 19 subfamily A member 1 ISO PCB 126, 138, 153, 180 RGD PMID:19464308 RGD:4890403 NCBI chr30:16,954,020...17,056,728
Ensembl chr30:16,957,215...16,988,353 		JBrowse link
G CYP4B1 cytochrome P450 family 4 subfamily B member 1 ISO RGD PMID:9310344 RGD:1626420 NCBI chr15:13,676,631...13,694,483
Ensembl chr15:13,676,371...13,694,705 		JBrowse link
G HSD17B3 hydroxysteroid 17-beta dehydrogenase 3 ISO Aroclor 1254 RGD PMID:18502095 RGD:4783624 NCBI chr 1:70,551,013...70,586,364
Ensembl chr 1:70,487,334...70,586,368 		JBrowse link
G SRD5A2 steroid 5 alpha-reductase 2 ISO Aroclor 1254 RGD PMID:16938428 RGD:4891899 NCBI chr17:25,017,113...25,056,156
Ensembl chr17:25,017,113...25,056,544 		JBrowse link
G STAR steroidogenic acute regulatory protein ISO Aroclor 1254 RGD PMID:19071209 RGD:4768197 NCBI chr16:27,326,355...27,331,025
Ensembl chr16:27,326,355...27,331,025 		JBrowse link
homogentisate catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G FAH fumarylacetoacetate hydrolase involved_in IBA GO_Central GO_REF:0000033 NCBI chr 3:57,300,422...57,326,546
Ensembl chr 3:57,300,441...57,326,486 		JBrowse link
kynurenine metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AADAT aminoadipate aminotransferase involved_in IEA Ensembl GO_REF:0000107 NCBI chr25:20,920,118...20,944,251
Ensembl chr25:20,920,139...20,945,387 		JBrowse link
G KMO kynurenine 3-monooxygenase involved_in IEA
IBA		 Ensembl
GO_Central		 GO_REF:0000033 GO_REF:0000107 NCBI chr 7:32,941,487...32,994,541
Ensembl chr 7:32,941,487...32,994,541 		JBrowse link
G KYAT1 kynurenine aminotransferase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:54,760,212...54,796,996
Ensembl chr 9:54,760,276...54,796,848 		JBrowse link
G KYAT3 kynurenine aminotransferase 3 involved_in ISO (PMID:19029248) UniProt PMID:19029248 NCBI chr 6:59,409,715...59,473,238
Ensembl chr 6:59,416,191...59,473,232 		JBrowse link
L-kynurenine catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G KYAT3 kynurenine aminotransferase 3 involved_in IEA UniProt GO_REF:0000041 NCBI chr 6:59,409,715...59,473,238
Ensembl chr 6:59,416,191...59,473,232 		JBrowse link
G KYNU kynureninase involved_in IEA UniProt GO_REF:0000041 GO_REF:0000104 NCBI chr19:45,022,450...45,150,977
Ensembl chr19:45,022,072...45,149,339 		JBrowse link
L-kynurenine metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G KMO kynurenine 3-monooxygenase ISO RGD PMID:23690293 RGD:13513904 NCBI chr 7:32,941,487...32,994,541
Ensembl chr 7:32,941,487...32,994,541 		JBrowse link
G KYAT1 kynurenine aminotransferase 1 ISO RGD PMID:7796908 RGD:9685040 NCBI chr 9:54,760,212...54,796,996
Ensembl chr 9:54,760,276...54,796,848 		JBrowse link
L-tryptophan catabolic process to kynurenine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AFMID arylformamidase involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:15866519) InterPro
UniProt
MGI		 PMID:15866519 GO_REF:0000002 GO_REF:0000041 GO_REF:0000104
G IDO1 indoleamine 2,3-dioxygenase 1 involved_in
acts_upstream_of_or_within		 ISO
IBA
IEA		 (PMID:11751753), (PMID:2419335) RGD
GO_Central
UniProt
MGI
InterPro		 PMID:2419335 PMID:10719243 PMID:11513477 PMID:11751753 GO_REF:0000002 GO_REF:0000033 GO_REF:0000104 RGD:2290190 RGD:2290543 NCBI chr16:25,391,759...25,407,161
Ensembl chr16:25,391,754...25,407,048 		JBrowse link
G IDO2 indoleamine 2,3-dioxygenase 2 involved_in
acts_upstream_of_or_within		 IEA
IBA
ISO		 (PMID:17499941)
(PMID:17671174)		 InterPro
GO_Central
UniProt
MGI
Ensembl		 PMID:17499941 PMID:17671174 GO_REF:0000002 GO_REF:0000033 GO_REF:0000104 GO_REF:0000107 NCBI chr16:25,319,035...25,375,085
Ensembl chr16:25,319,035...25,385,515 		JBrowse link
G KYNU kynureninase involved_in IBA GO_Central GO_REF:0000033 NCBI chr19:45,022,450...45,150,977
Ensembl chr19:45,022,072...45,149,339 		JBrowse link
G TDO2 tryptophan 2,3-dioxygenase involved_in IEA InterPro
UniProt
Ensembl		 GO_REF:0000002 GO_REF:0000041 GO_REF:0000104 GO_REF:0000107 NCBI chr15:53,406,110...53,424,260
Ensembl chr15:53,405,957...53,423,958 		JBrowse link
mandelate metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G HAO2 hydroxyacid oxidase 2 ISO RGD PMID:8508789 RGD:70759 NCBI chr17:56,505,463...56,529,441
Ensembl chr17:56,505,506...56,528,954 		JBrowse link
nitrobenzene metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GSTM3 glutathione S-transferase mu 3 involved_in ISO (PMID:8373352) BHF-UCL PMID:8373352 NCBI chr 6:42,187,869...42,191,274
Ensembl chr 6:42,187,967...42,191,273 		JBrowse link
G LOC479912 glutathione S-transferase Mu 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:12069689) Ensembl
MGI		 PMID:12069689 GO_REF:0000107 NCBI chr 6:42,201,697...42,207,886 JBrowse link
phenylacetate catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACAA1 acetyl-CoA acyltransferase 1 involved_in IBA GO_Central GO_REF:0000033 NCBI chr23:7,889,481...7,901,324
Ensembl chr23:7,889,500...7,901,229 		JBrowse link
G PON3 paraoxonase 3 ISO RGD PMID:12946270 RGD:1303961 NCBI chr14:20,615,180...20,642,807
Ensembl chr14:20,565,641...20,642,985 		JBrowse link
phthalate metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CMPK1 cytidine/uridine monophosphate kinase 1 ISO di-(2-ethylhexyl)phthalate RGD PMID:16400681 RGD:5133250 NCBI chr15:13,324,235...13,357,387
Ensembl chr15:13,326,185...13,358,152 		JBrowse link
G CYP17A1 cytochrome P450 family 17 subfamily A member 1 ISO RGD PMID:16809437 RGD:1601046 NCBI chr28:15,292,959...15,298,896
Ensembl chr28:15,293,106...15,298,852 		JBrowse link
G CYP19A1 cytochrome P450 family 19 subfamily A member 1 ISO di-(2-ethylhexyl) phthalate RGD PMID:20920559 RGD:4890045 NCBI chr30:16,954,020...17,056,728
Ensembl chr30:16,957,215...16,988,353 		JBrowse link
G SRD5A2 steroid 5 alpha-reductase 2 ISO RGD PMID:20954080 RGD:4891498 NCBI chr17:25,017,113...25,056,156
Ensembl chr17:25,017,113...25,056,544 		JBrowse link
G STAR steroidogenic acute regulatory protein ISO RGD PMID:16809437 RGD:1601046 NCBI chr16:27,326,355...27,331,025
Ensembl chr16:27,326,355...27,331,025 		JBrowse link
G TH tyrosine hydroxylase ISO mono-(2-ethylhexyl) phthalate RGD PMID:21145954 RGD:5128805 NCBI chr18:46,327,136...46,334,973
Ensembl chr18:46,327,137...46,335,602 		JBrowse link
stilbene catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G EPHX2 epoxide hydrolase 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr25:30,045,040...30,107,110
Ensembl chr25:30,045,291...30,107,110 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 22103
    cellular process 21633
      metabolic process 15381
        benzene-containing compound metabolic process 30
          (+)-pinoresinol metabolic process + 0
          (-)-pinoresinol metabolic process + 0
          1,1,1-trichloro-2,2-bis-(4-chlorophenyl)ethane metabolic process + 0
          1,2,4-trichlorobenzene catabolic process 0
          1,4-dichlorobenzene catabolic process 0
          1-(3,5-dichloro-2,6-dihydroxy-4-methoxyphenyl)hexan-1-one metabolic process + 0
          2,4,5-trichlorophenoxyacetic acid metabolic process + 0
          2,4-dichlorobenzoate metabolic process + 0
          2,4-dichlorophenoxyacetic acid metabolic process + 0
          2-aminobenzenesulfonate metabolic process + 0
          2-chloro-N-isopropylacetanilide metabolic process + 0
          3,4-dihydroxybenzoate metabolic process + 0
          3-chlorocatechol metabolic process + 0
          3-phenylpropionate metabolic process + 0
          4-carboxy-4'-sulfoazobenzene metabolic process 0
          4-chlorobiphenyl metabolic process 1
          4-toluenecarboxylate metabolic process + 0
          anthranilate metabolic process + 3
          benzene metabolic process + 0
          benzoate metabolic process + 0
          benzonitrile metabolic process 0
          biphenyl metabolic process + 8
          bromoxynil metabolic process 0
          chlorobenzene catabolic process 0
          cinnamic acid metabolic process + 0
          ethylbenzene catabolic process + 0
          eugenol metabolic process + 0
          gallate catabolic process + 0
          gerfelin metabolic process + 0
          homogentisate metabolic process + 1
          iprodione metabolic process 0
          kynurenine metabolic process + 9
          mandelate metabolic process + 1
          methylgallate metabolic process + 0
          monodictyphenone metabolic process + 0
          nitrobenzene metabolic process + 2
          o-orsellinic acid metabolic process + 0
          olivetolic acid biosynthetic process 0
          p-cumate metabolic process + 0
          para-aminobenzoic acid metabolic process + 0
          pentachlorophenol metabolic process + 0
          phenylacetate catabolic process 2
          phenylmercury acetate metabolic process + 0
          phthalate metabolic process + 6
          salicylic acid metabolic process + 0
          sinapate metabolic process + 0
          stilbene metabolic process + 1
          styrene metabolic process + 0
          toluene-containing compound metabolic process + 0
          vanillin metabolic process + 0
          xylene metabolic process + 0
paths to the root