PON3 (paraoxonase 3) - Rat Genome Database

Name: PON3
Creator: Rat Genome Database
License: Creative Commons CC BY 4.0
Keywords: Rat Gene RGD Genome

Advanced Search (OLGA)

Gene: PON3 (paraoxonase 3) Canis lupus familiaris

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Symbol:

PON3

Name:

paraoxonase 3

RGD ID:

12191076

Description:

ENCODES a protein that exhibits acyl-L-homoserine-lactone lactonohydrolase activity (ortholog); arylesterase activity (ortholog); dihydrocoumarin hydrolase activity (ortholog); INVOLVED IN carboxylic acid catabolic process (ortholog); coumarin catabolic process (ortholog); establishment of localization in cell (ortholog); ASSOCIATED WITH Alzheimer's disease (ortholog); amyotrophic lateral sclerosis (ortholog); atherosclerosis (ortholog); FOUND IN extracellular space (ortholog)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

serum paraoxonase/lactonase 3

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	PON3 (paraoxonase 3)	HGNC	Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoMCL, Panther, PhylomeDB, Treefam
Mus musculus (house mouse):	Pon3 (paraoxonase 3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus norvegicus (Norway rat):	Pon3 (paraoxonase 3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Pon3 (paraoxonase 3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	PON3 (paraoxonase 3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Pon3 (paraoxonase 3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	PON3 (paraoxonase 3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	PON3 (paraoxonase 3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Pon3 (paraoxonase 3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Other homologs ²
Homo sapiens (human):	PON1 (paraoxonase 1)	HGNC	EggNOG, OrthoDB

Latest Assembly:

CanFam3.1 - Dog CanFam3.1 Assembly

Position:

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	14	20,615,180 - 20,642,807 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	14	20,565,641 - 20,642,985 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	14	20,174,181 - 20,202,180 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	14	20,437,560 - 20,465,291 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	14	20,437,057 - 20,465,276 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	14	20,582,215 - 20,609,982 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	14	20,317,344 - 20,345,279 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	14	20,574,717 - 20,602,546 (-)	NCBI		UU_Cfam_GSD_1.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

Alzheimer's disease (ISO)

amyotrophic lateral sclerosis (ISO)

atherosclerosis (ISO)

autism spectrum disorder (ISO)

celiac disease (ISO)

Crohn's disease (ISO)

pleomorphic xanthoastrocytoma (ISO)

ulcerative colitis (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

carboxylic acid catabolic process (ISO)

coumarin catabolic process (ISO)

establishment of localization in cell (ISO)

lactone catabolic process (ISO)

negative regulation of superoxide anion generation (ISO)

phenylacetate catabolic process (ISO)

regulation of cellular response to drug (ISO)

renal sodium ion transport (ISO)

Cellular Component

extracellular space (ISO)

Molecular Function

acyl-L-homoserine-lactone lactonohydrolase activity (ISO)

arylesterase activity (IEA,ISO)

dihydrocoumarin hydrolase activity (ISO)

hydrolase activity (IEA)

metal ion binding (IEA)

protein homodimerization activity (ISO)

References

Additional References at PubMed

PMID:22301074	PMID:30032202

Genomics

Comparative Map Data

PON3
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	14	20,615,180 - 20,642,807 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	14	20,565,641 - 20,642,985 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	14	20,174,181 - 20,202,180 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	14	20,437,560 - 20,465,291 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	14	20,437,057 - 20,465,276 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	14	20,582,215 - 20,609,982 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	14	20,317,344 - 20,345,279 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	14	20,574,717 - 20,602,546 (-)	NCBI		UU_Cfam_GSD_1.0

PON3
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	7	95,359,872 - 95,396,375 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	7	95,359,872 - 95,396,375 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	7	94,989,184 - 95,025,687 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	7	94,827,120 - 94,863,623 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	7	94,633,925 - 94,670,313	NCBI
Celera	7	89,687,888 - 89,724,394 (-)	NCBI		Celera
Cytogenetic Map	7	q21.3	NCBI
HuRef	7	89,596,240 - 89,632,745 (-)	NCBI		HuRef
CHM1_1	7	94,919,217 - 94,955,721 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	7	96,596,019 - 96,632,523 (-)	NCBI		T2T-CHM13v2.0
CRA_TCAGchr7v2	7	94,318,186 - 94,354,692 (-)	NCBI

Pon3
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	6	5,216,253 - 5,256,236 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	6	5,220,852 - 5,256,286 (-)	Ensembl		GRCm39 Ensembl
GRCm38	6	5,216,256 - 5,256,285 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	6	5,220,852 - 5,256,286 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	6	5,170,852 - 5,206,233 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	6	5,170,852 - 5,206,233 (-)	NCBI		MGSCv36	mm8
Celera	6	5,367,370 - 5,403,410 (-)	NCBI		Celera
Cytogenetic Map	6	A1	NCBI
cM Map	6	1.99	NCBI

Pon3
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	4	34,323,546 - 34,350,244 (-)	NCBI		GRCr8
mRatBN7.2	4	33,356,983 - 33,383,681 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	4	33,349,168 - 33,383,855 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	4	38,316,014 - 38,342,716 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	4	34,242,154 - 34,268,854 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	4	32,651,934 - 32,678,640 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	4	30,311,981 - 30,338,679 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	4	30,311,982 - 30,338,679 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	4	30,218,888 - 30,245,586 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	4	30,000,505 - 30,027,203 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	4	30,039,834 - 30,066,533 (-)	NCBI
Celera	4	28,883,809 - 28,910,507 (-)	NCBI		Celera
Cytogenetic Map	4	q21	NCBI

Pon3
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955432	11,942,922 - 11,983,504 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955432	11,945,383 - 11,983,417 (-)	NCBI	ChiLan1.0	ChiLan1.0

PON3
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	6	113,197,534 - 113,238,696 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	7	161,462,173 - 161,503,379 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	7	87,314,788 - 87,354,020 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	7	100,902,432 - 100,941,611 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	7	100,902,432 - 100,941,611 (-)	Ensembl	panpan1.1		panPan2

Pon3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405118	33,933,867 - 33,961,080 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936585	4,902,289 - 4,929,556 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936585	4,902,430 - 4,928,377 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

PON3
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	9	74,991,277 - 75,017,942 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	9	74,983,040 - 75,017,947 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	9	82,185,788 - 82,193,864 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

PON3
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	21	53,645,406 - 53,675,066 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	21	53,645,384 - 53,674,812 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666042	50,670,307 - 50,702,561 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Pon3
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624813	2,022,482 - 2,051,330 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624813	2,023,025 - 2,051,319 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in PON3
227 total Variants

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_022427375	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_022427376	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038435504	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038494578	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038494579	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038494580	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038556863	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038556864	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038556865	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038620802	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038620803	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038620804	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038686492	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038686493	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038686494	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_532467	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AAEX04000014	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAAHUQ010000156	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAAQRD010000017	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAAUVH010000208	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	REHQ01000014	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSCAFT00845036491 ⟹ ENSCAFP00845028557

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0 Ensembl	14	20,437,057 - 20,465,276 (-)	Ensembl

Ensembl Acc Id:

ENSCAFT00845036571 ⟹ ENSCAFP00845028618

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0 Ensembl	14	20,438,204 - 20,464,633 (-)	Ensembl

RefSeq Acc Id:

XM_022427375 ⟹ XP_022283083

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1	14	20,615,180 - 20,642,807 (-)	NCBI
Dog10K_Boxer_Tasha	14	20,174,181 - 20,201,989 (-)	NCBI

Sequence:

show sequence

TGTCTCGGGATCAATGCTCCGTCTCATCTTCCGTCTTGCCTTCCAGAAACAGCAAGTTTTGGGC
TCCGAACTCAGCTCCCCGAGGTCCCCCGACTCTTCAGCTCCCCGACAAAGAACTAATGCATTTC
GAAAAGTGGAGCCAGTAGAACCGCAGAACTGCCGCCTTATTGAGGGACTCGAAAATGGCTCTGA
AGATATTGATATACTTCCTAGTGGGCTGGCTTTTATCTCCAGTGGATTAAAATATCCAGGCCTG
CCAAGTTTTGCACCAGATGAGCCAGGACAAATTTTCTTGATGGATATGAATGAGCAAAACCCAA
AGGTCCAGGCATTAAACATCAGTGATGGTTTTGACAAAGCATCATTTAATCCACACGGAATCAG
TACTTTCATCGATGAAGACCATACTGTGTATCTTTACGTTGTGAATCATCCCCACATGAAGTCC
ACCGTGGAGAAATTTAAGTTTGAGGAACAACAACGTTCTCTTGTACACCTAAAAACTATAAAAC
ATGAACTTCTCAAAAGTGTGAATGACATTGTGGTTCTTGGACCAGAACAGTTTTATGCCACAAG
AGACCATTACTTTACCAACTTCTTCTTGGTACTATTCGAGATGATCATGGATCTTCATTGGACT
TATGCTGTTTTCTACAGTCCAAGAGAGGTCAAAGTCGTAGCCAAAGGGTTTAGCTCTGCCAATG
GGATCACAGTCTCACTAGACAAAAAGTATATCTACATAGCTGATGTAACTGCTCAGAACATTCA
CGTACTGAAAAAACATGAGAACTGGGATTTAACTCAAGTGAAGGTAATACATTTGGGCACCTTA
GTGGATAACTTAACTGTGGATCCTGATACTGGAGATATTTGGGCAGGATGCCATCCTGACGGCA
AGAAGCTGCTGATCTATAACCCTGAGGATCCTCCAGGGTCTGAAGTACTTCGCATCCAGGATGT
TTTGTCTGAGAAGCCTAAGATAAGCACCGAGTACGCCAATAATGGCTCTGTGCTTCAGGGAAGC
ACCGTGGCTTCTGTGTACCACGGAAAACTTCTCATAGGCACGGTATTTCACAAAGCTCTGTACT
GTTTGCTTTAGATCCCAGACATTCCAAAAAAGTCTTGTTAACCAATGAAAGACAAAATTGCAAG
CAGCAAAATAAATGTGTTTATTTGGGGTCTCAGGGATTGCAATGTGAGAAATACAGATTCGGCT
AGAATTGAAAGCTTGATCTGGGGAGACAAAGGAGGTTGGAGTTTTTAAAGAGGAGAGAAGGGAT
TTACATAAGTTGTTTGAAGCAAAGGTTTTTGGTGTTGGTATAGCTACAGTTACACTAATCTACG
TGTGATTGGTTGCTAGGGCTAGGCAGAAAGTCCACTTATGTCCATTTTAACACCTACTAGATGA
CTTGGCTTTTAGCTGAGTTTAGGAAAACTTCTGAGAATTTTATATAGAGCATGTGCATAAGCCC
CACCTCCTTGATGTCCTTCAAGCTCTATTTTAAATAACTCTTTTAGTAATTGTCACTCAATTTT
ATTGTCTCTGTTGTCAATCTACATGTTTGGTAAAAATAAACCCATAATTATATGATAAGTGGAA
TTGTACATAAATGACAAATACCAATAA

hide sequence

RefSeq Acc Id:

XM_038435504 ⟹ XP_038291432

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
Dog10K_Boxer_Tasha	14	20,174,181 - 20,202,180 (-)	NCBI

RefSeq Acc Id:

XM_038494578 ⟹ XP_038350506

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UMICH_Zoey_3.1	14	20,582,215 - 20,609,982 (-)	NCBI

RefSeq Acc Id:

XM_038494579 ⟹ XP_038350507

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UMICH_Zoey_3.1	14	20,582,215 - 20,609,791 (-)	NCBI

RefSeq Acc Id:

XM_038494580 ⟹ XP_038350508

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UMICH_Zoey_3.1	14	20,582,215 - 20,609,368 (-)	NCBI

RefSeq Acc Id:

XM_038556863 ⟹ XP_038412791

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UU_Cfam_GSD_1.0	14	20,574,717 - 20,602,546 (-)	NCBI

RefSeq Acc Id:

XM_038556864 ⟹ XP_038412792

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UU_Cfam_GSD_1.0	14	20,574,717 - 20,602,355 (-)	NCBI

RefSeq Acc Id:

XM_038556865 ⟹ XP_038412793

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UU_Cfam_GSD_1.0	14	20,574,717 - 20,601,941 (-)	NCBI

RefSeq Acc Id:

XM_038620802 ⟹ XP_038476730

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UNSW_CanFamBas_1.0	14	20,317,344 - 20,345,279 (-)	NCBI

RefSeq Acc Id:

XM_038620803 ⟹ XP_038476731

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UNSW_CanFamBas_1.0	14	20,317,344 - 20,345,088 (-)	NCBI

RefSeq Acc Id:

XM_038620804 ⟹ XP_038476732

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UNSW_CanFamBas_1.0	14	20,317,344 - 20,344,679 (-)	NCBI

RefSeq Acc Id:

XM_038686492 ⟹ XP_038542420

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0	14	20,437,560 - 20,465,291 (-)	NCBI

RefSeq Acc Id:

XM_038686493 ⟹ XP_038542421

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0	14	20,437,560 - 20,465,100 (-)	NCBI

RefSeq Acc Id:

XM_038686494 ⟹ XP_038542422

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0	14	20,437,560 - 20,464,677 (-)	NCBI

RefSeq Acc Id:

XM_532467 ⟹ XP_532467

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1	14	20,615,180 - 20,642,396 (-)	NCBI
Dog10K_Boxer_Tasha	14	20,174,181 - 20,201,580 (-)	NCBI

Sequence:

show sequence

CGGGGGCGGGAGCCTGCCCGCCGCACCCTTGGCAGCGCTGGGCGCCCGCTCGTCGCCACCGGGC
ACCCCGGGCGTCGGAGACCATGGGGAAGCTGATGGTGCTGACCCTGCTGGGGGCCGGCCTGGCC
TTAGTCGGGGAGAGGCTGGTGGCCTTTAGACAAAGAACTAATGCATTTCGAAAAGTGGAGCCAG
TAGAACCGCAGAACTGCCGCCTTATTGAGGGACTCGAAAATGGCTCTGAAGATATTGATATACT
TCCTAGTGGGCTGGCTTTTATCTCCAGTGGATTAAAATATCCAGGCCTGCCAAGTTTTGCACCA
GATGAGCCAGGACAAATTTTCTTGATGGATATGAATGAGCAAAACCCAAAGGTCCAGGCATTAA
ACATCAGTGATGGTTTTGACAAAGCATCATTTAATCCACACGGAATCAGTACTTTCATCGATGA
AGACCATACTGTGTATCTTTACGTTGTGAATCATCCCCACATGAAGTCCACCGTGGAGAAATTT
AAGTTTGAGGAACAACAACGTTCTCTTGTACACCTAAAAACTATAAAACATGAACTTCTCAAAA
GTGTGAATGACATTGTGGTTCTTGGACCAGAACAGTTTTATGCCACAAGAGACCATTACTTTAC
CAACTTCTTCTTGGTACTATTCGAGATGATCATGGATCTTCATTGGACTTATGCTGTTTTCTAC
AGTCCAAGAGAGGTCAAAGTCGTAGCCAAAGGGTTTAGCTCTGCCAATGGGATCACAGTCTCAC
TAGACAAAAAGTATATCTACATAGCTGATGTAACTGCTCAGAACATTCACGTACTGAAAAAACA
TGAGAACTGGGATTTAACTCAAGTGAAGGTAATACATTTGGGCACCTTAGTGGATAACTTAACT
GTGGATCCTGATACTGGAGATATTTGGGCAGGATGCCATCCTGACGGCAAGAAGCTGCTGATCT
ATAACCCTGAGGATCCTCCAGGGTCTGAAGTACTTCGCATCCAGGATGTTTTGTCTGAGAAGCC
TAAGATAAGCACCGAGTACGCCAATAATGGCTCTGTGCTTCAGGGAAGCACCGTGGCTTCTGTG
TACCACGGAAAACTTCTCATAGGCACGGTATTTCACAAAGCTCTGTACTGTTTGCTTTAGATCC
CAGACATTCCAAAAAAGTCTTGTTAACCAATGAAAGACAAAATTGCAAGCAGCAAAATAAATGT
GTTTATTTGGGGTCTCAGGGATTGCAATGTGAGAAATACAGATTCGGCTAGAATTGAAAGCTTG
ATCTGGGGAGACAAAGGAGGTTGGAGTTTTTAAAGAGGAGAGAAGGGATTTACATAAGTTGTTT
GAAGCAAAGGTTTTTGGTGTTGGTATAGCTACAGTTACACTAATCTACGTGTGATTGGTTGCTA
GGGCTAGGCAGAAAGTCCACTTATGTCCATTTTAACACCTACTAGATGACTTGGCTTTTAGCTG
AGTTTAGGAAAACTTCTGAGAATTTTATATAGAGCATGTGCATAAGCCCCACCTCCTTGATGTC
CTTCAAGCTCTATTTTAAATAACTCTTTTAGTAATTGTCACTCAATTTTATTGTCTCTGTTGTC
AATCTACATGTTTGGTAAAAATAAACCCATAATTATATGATAAGTGGAATTGTACATAAATGAC
AAATACCAATAA

hide sequence

Protein Sequences


Protein RefSeqs	XP_022283083	(Get FASTA)	NCBI Sequence Viewer
	XP_038291432	(Get FASTA)	NCBI Sequence Viewer
	XP_038350506	(Get FASTA)	NCBI Sequence Viewer
	XP_038350507	(Get FASTA)	NCBI Sequence Viewer
	XP_038350508	(Get FASTA)	NCBI Sequence Viewer
	XP_038412791	(Get FASTA)	NCBI Sequence Viewer
	XP_038412792	(Get FASTA)	NCBI Sequence Viewer
	XP_038412793	(Get FASTA)	NCBI Sequence Viewer
	XP_038476730	(Get FASTA)	NCBI Sequence Viewer
	XP_038476731	(Get FASTA)	NCBI Sequence Viewer
	XP_038476732	(Get FASTA)	NCBI Sequence Viewer
	XP_038542420	(Get FASTA)	NCBI Sequence Viewer
	XP_038542421	(Get FASTA)	NCBI Sequence Viewer
	XP_038542422	(Get FASTA)	NCBI Sequence Viewer
	XP_532467	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSCAFP00000056112.1
	ENSCAFP00000063219.1
	ENSCAFP00030029319.1
	ENSCAFP00040022218.1
	ENSCAFP00845028557.1
	ENSCAFP00845028618.1

RefSeq Acc Id:	XP_532467 ⟸ XM_532467
- Peptide Label:	isoform X3
- UniProtKB:	A0A8C0KDK5 (UniProtKB/TrEMBL)
- Sequence:	show sequence MGKLMVLTLLGAGLALVGERLVAFRQRTNAFRKVEPVEPQNCRLIEGLENGSEDIDILPSGLAF ISSGLKYPGLPSFAPDEPGQIFLMDMNEQNPKVQALNISDGFDKASFNPHGISTFIDEDHTVYL YVVNHPHMKSTVEKFKFEEQQRSLVHLKTIKHELLKSVNDIVVLGPEQFYATRDHYFTNFFLVL FEMIMDLHWTYAVFYSPREVKVVAKGFSSANGITVSLDKKYIYIADVTAQNIHVLKKHENWDLT QVKVIHLGTLVDNLTVDPDTGDIWAGCHPDGKKLLIYNPEDPPGSEVLRIQDVLSEKPKISTEY ANNGSVLQGSTVASVYHGKLLIGTVFHKALYCLL hide sequence

RefSeq Acc Id:

XP_022283083 ⟸ XM_022427375

- Peptide Label:

isoform X2

- Sequence:

show sequence

MLRLIFRLAFQKQQVLGSELSSPRSPDSSAPRQRTNAFRKVEPVEPQNCRLIEGLENGSEDIDI
LPSGLAFISSGLKYPGLPSFAPDEPGQIFLMDMNEQNPKVQALNISDGFDKASFNPHGISTFID
EDHTVYLYVVNHPHMKSTVEKFKFEEQQRSLVHLKTIKHELLKSVNDIVVLGPEQFYATRDHYF
TNFFLVLFEMIMDLHWTYAVFYSPREVKVVAKGFSSANGITVSLDKKYIYIADVTAQNIHVLKK
HENWDLTQVKVIHLGTLVDNLTVDPDTGDIWAGCHPDGKKLLIYNPEDPPGSEVLRIQDVLSEK
PKISTEYANNGSVLQGSTVASVYHGKLLIGTVFHKALYCLL

hide sequence

RefSeq Acc Id:	XP_038350506 ⟸ XM_038494578
- Peptide Label:	isoform X1

RefSeq Acc Id:	XP_038350507 ⟸ XM_038494579
- Peptide Label:	isoform X2

RefSeq Acc Id:	XP_038350508 ⟸ XM_038494580
- Peptide Label:	isoform X3

RefSeq Acc Id:	XP_038476730 ⟸ XM_038620802
- Peptide Label:	isoform X1

RefSeq Acc Id:	XP_038476731 ⟸ XM_038620803
- Peptide Label:	isoform X2

RefSeq Acc Id:	XP_038476732 ⟸ XM_038620804
- Peptide Label:	isoform X3

RefSeq Acc Id:	XP_038542420 ⟸ XM_038686492
- Peptide Label:	isoform X1

RefSeq Acc Id:	XP_038542421 ⟸ XM_038686493
- Peptide Label:	isoform X2

RefSeq Acc Id:	XP_038542422 ⟸ XM_038686494
- Peptide Label:	isoform X3
- UniProtKB:	A0A8C0KDK5 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038291432 ⟸ XM_038435504
- Peptide Label:	isoform X1

RefSeq Acc Id:	XP_038412791 ⟸ XM_038556863
- Peptide Label:	isoform X1

RefSeq Acc Id:	XP_038412792 ⟸ XM_038556864
- Peptide Label:	isoform X2

RefSeq Acc Id:	XP_038412793 ⟸ XM_038556865
- Peptide Label:	isoform X3
- UniProtKB:	A0A8C0KDK5 (UniProtKB/TrEMBL)

Ensembl Acc Id:

ENSCAFP00845028618 ⟸ ENSCAFT00845036571

Ensembl Acc Id:

ENSCAFP00845028557 ⟸ ENSCAFT00845036491

Promoters

RGD ID:

13685755

Promoter ID:

EPDNEW_C3825

Type:

single initiation site

Name:

PON3_1

Description:

paraoxonase 3

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1	14	20,642,544 - 20,642,604	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSCAFG00000002118	Ensembl, UniProtKB/TrEMBL
	ENSCAFG00030018030	UniProtKB/TrEMBL
	ENSCAFG00040013767	UniProtKB/TrEMBL
	ENSCAFG00845020697	Ensembl, UniProtKB/TrEMBL
Ensembl Transcript	ENSCAFT00000064726.2	UniProtKB/TrEMBL
	ENSCAFT00000086443.2	UniProtKB/TrEMBL
	ENSCAFT00030033598.1	UniProtKB/TrEMBL
	ENSCAFT00040025556.1	UniProtKB/TrEMBL
	ENSCAFT00845036491.1	UniProtKB/TrEMBL
	ENSCAFT00845036571.1	UniProtKB/TrEMBL
Gene3D-CATH	2.120.10.30	UniProtKB/TrEMBL
InterPro	6-blade_b-propeller_TolB-like	UniProtKB/TrEMBL
	Arylesterase	UniProtKB/TrEMBL
	Serum_paraoxonase/arylesterase	UniProtKB/TrEMBL
NCBI Gene	PON3	ENTREZGENE
PANTHER	PARAOXONASE	UniProtKB/TrEMBL
	SERUM PARAOXONASE/LACTONASE 3	UniProtKB/TrEMBL
Pfam	Arylesterase	UniProtKB/TrEMBL
PRINTS	PARAOXONASE	UniProtKB/TrEMBL
Superfamily-SCOP	Calcium-dependent phosphotriesterase	UniProtKB/TrEMBL
UniProt	A0A8C0KDK5	ENTREZGENE
	A0A8C0SK41_CANLF	UniProtKB/TrEMBL
	A0A8I3PAM3_CANLF	UniProtKB/TrEMBL
	A0A8I3PAS3_CANLF	UniProtKB/TrEMBL
	A0A8P0T8A9_CANLF	UniProtKB/TrEMBL
VGNC ID	VGNC:44814	ENTREZGENE

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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Imported Disease Annotations - CTD

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Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD