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ONTOLOGY REPORT - ANNOTATIONS


Term:calcium import into the mitochondrion
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Accession:GO:0036444 term browser browse the term
Definition:A process in which a calcium ion (Ca2+) is transported from the cytosol into the mitochondrial matrix.
Synonyms:exact_synonym: calcium ion transmembrane import into mitochondrion;   mitochondrial calcium ion import;   mitochondrial calcium uptake
 broad_synonym: calcium ion import into mitochondrion



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calcium import into the mitochondrion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Afg3l2 AFG3 like matrix AAA peptidase subunit 2 involved_in ISO (PMID:27642048) RGD PMID:27642048 NCBI chr18:60,954,268...60,999,110
Ensembl chr18:60,954,268...60,999,110
JBrowse link
G ENSRNOG00000066493 involved_in IEA GO_REF:0000104 UniProt GO_REF:0000104 Ensembl chr19:39,079,782...39,080,340 JBrowse link
G Hspa9 heat shock protein family A (Hsp70) member 9 involved_in IMP PMID:17178908 UniProt PMID:17178908 RGD:405650386 NCBI chr18:26,536,131...26,554,294
Ensembl chr18:26,535,798...26,554,292
JBrowse link
G Itpr1 inositol 1,4,5-trisphosphate receptor, type 1 involved_in IMP PMID:17178908 UniProt PMID:17178908 RGD:405650386 NCBI chr 4:141,187,377...141,554,240
Ensembl chr 4:141,187,418...141,510,491
JBrowse link
G Maip1 matrix AAA peptidase interacting protein 1 involved_in ISO
ISS
(PMID:27642048)
GO_REF:0000024
RGD
UniProt
PMID:27642048 GO_REF:0000024 NCBI chr 9:58,978,901...58,986,831
Ensembl chr 9:58,978,716...58,986,829
JBrowse link
G Mcu mitochondrial calcium uniporter acts_upstream_of_or_within
involved_in
ISO
IBA
(PMID:22925203)
(PMID:23755363), (PMID:29954988), (PMID:29995857), (PMID:30454562), (PMID:31080062), (PMID:32494073), (PMID:32762847), (PMID:33296646)
GO_REF:0000033
RGD
GO_Central
PMID:22925203 PMID:23755363 PMID:29954988 PMID:29995857 PMID:30454562 More... GO_REF:0000033 NCBI chr20:27,417,529...27,580,110
Ensembl chr20:27,417,526...27,580,110
JBrowse link
G Mcub mitochondrial calcium uniporter dominant negative subunit beta involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 2:218,479,301...218,549,594
Ensembl chr 2:218,479,301...218,549,593
JBrowse link
G Mcur1 mitochondrial calcium uniporter regulator 1 involved_in ISO
IBA
(PMID:26445506), (PMID:27184846)
GO_REF:0000033
RGD
GO_Central
PMID:26445506 PMID:27184846 GO_REF:0000033 NCBI chr17:21,142,526...21,159,651
Ensembl chr17:21,141,602...21,159,651
JBrowse link
G Micu1 mitochondrial calcium uptake 1 involved_in ISS
ISO
IBA
IEA
GO_REF:0000024
(PMID:26903221), (PMID:27642082), (PMID:28615291), (PMID:30638448), (PMID:31397067), (PMID:32148862), (PMID:32494073), (PMID:32667285), (PMID:32762847), (PMID:32790952), (PMID:36206740)
GO_REF:0000033
GO_REF:0000107
UniProt
RGD
GO_Central
Ensembl
PMID:26903221 PMID:27642082 PMID:28615291 PMID:30638448 PMID:31397067 More... GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 NCBI chr20:27,668,681...27,816,322
Ensembl chr20:27,668,747...27,814,964
JBrowse link
G Micu2 mitochondrial calcium uptake 2 involved_in ISS
ISO
IBA
IEA
GO_REF:0000024
(PMID:26903221), (PMID:28615291), (PMID:30699349), (PMID:31397067), (PMID:32148862), (PMID:32494073), (PMID:32667285), (PMID:32762847), (PMID:32790952)
GO_REF:0000033
GO_REF:0000107
UniProt
RGD
GO_Central
Ensembl
PMID:26903221 PMID:28615291 PMID:30699349 PMID:31397067 PMID:32148862 More... GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 NCBI chr15:32,064,872...32,146,874
Ensembl chr15:32,064,875...32,147,094
JBrowse link
G Micu3 mitochondrial calcium uptake family, member 3 involved_in IBA
IDA
ISO
GO_REF:0000033
PMID:31862210
(PMID:29725115)
GO_Central
RGD
PMID:29725115 PMID:31862210 GO_REF:0000033, RGD:405650270 NCBI chr16:51,919,859...52,010,705
Ensembl chr16:51,925,225...52,010,613
JBrowse link
G Opa1 OPA1, mitochondrial dynamin like GTPase IMP RGD PMID:24085037 RGD:13208948 NCBI chr11:71,108,100...71,185,170
Ensembl chr11:71,109,873...71,185,109
JBrowse link
G Slc25a23 solute carrier family 25 member 23 involved_in ISO (PMID:24430870) RGD PMID:24430870 NCBI chr 9:1,882,636...1,898,369
Ensembl chr 9:1,882,621...1,898,561
JBrowse link
G Smdt1 single-pass membrane protein with aspartate-rich tail 1 acts_upstream_of_or_within
involved_in
ISO
IBA
(PMID:22925203)
(PMID:27099988), (PMID:27642048), (PMID:31080062), (PMID:32315830), (PMID:32494073), (PMID:32762847), (PMID:33296646)
GO_REF:0000033
RGD
GO_Central
PMID:22925203 PMID:27099988 PMID:27642048 PMID:31080062 PMID:32315830 More... GO_REF:0000033 NCBI chr 7:113,862,162...113,865,245
Ensembl chr 7:113,860,611...113,865,226
JBrowse link
G Vdac1 voltage-dependent anion channel 1 involved_in IMP PMID:11485562 UniProt PMID:11485562 RGD:405650210 NCBI chr10:36,532,306...36,559,642
Ensembl chr10:36,532,244...36,559,640
JBrowse link
negative regulation of calcium import into the mitochondrion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akt1 AKT serine/threonine kinase 1 IMP RGD PMID:24601882 RGD:39128160 NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921
JBrowse link
G Mcub mitochondrial calcium uniporter dominant negative subunit beta involved_in ISO (PMID:31533452) RGD PMID:31533452 NCBI chr 2:218,479,301...218,549,594
Ensembl chr 2:218,479,301...218,549,593
JBrowse link
G Ucp2 uncoupling protein 2 involved_in ISO (PMID:27642082) RGD PMID:27642082 NCBI chr 1:154,839,242...154,845,612
Ensembl chr 1:154,839,209...154,845,611
JBrowse link
G Vdac1 voltage-dependent anion channel 1 involved_in ISO (PMID:32047033) RGD PMID:32047033 NCBI chr10:36,532,306...36,559,642
Ensembl chr10:36,532,244...36,559,640
JBrowse link
regulation of calcium import into the mitochondrion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Afg3l2 AFG3 like matrix AAA peptidase subunit 2 involved_in ISO (PMID:28396416) RGD PMID:28396416 NCBI chr18:60,954,268...60,999,110
Ensembl chr18:60,954,268...60,999,110
JBrowse link
G Psen2 presenilin 2 involved_in ISO (PMID:21285369) RGD PMID:21285369 NCBI chr13:91,967,506...91,993,240
Ensembl chr13:91,967,983...91,993,174
JBrowse link
G Spg7 SPG7 matrix AAA peptidase subunit, paraplegin involved_in ISS GO_REF:0000024 UniProt GO_REF:0000024 NCBI chr19:51,117,088...51,151,228
Ensembl chr19:51,117,057...51,150,484
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19692
    cellular process 18168
      transmembrane transport 1594
        mitochondrial transmembrane transport 112
          mitochondrial calcium ion transmembrane transport 24
            calcium import into the mitochondrion 19
              calcium import into the mitochondrion involved in negative regulation of presynaptic cytosolic calcium concentration 0
              negative regulation of calcium import into the mitochondrion 4
              positive regulation of calcium import into the mitochondrion 0
              regulation of calcium import into the mitochondrion + 7
Path 2
Term Annotations click to browse term
  biological_process 19692
    localization 5613
      establishment of localization 4924
        transport 4612
          monoatomic ion transport 1301
            monoatomic cation transport 1099
              metal ion transport 940
                calcium ion transport 458
                  calcium ion transmembrane transport 335
                    mitochondrial calcium ion transmembrane transport 24
                      calcium import into the mitochondrion 19
                        calcium import into the mitochondrion involved in negative regulation of presynaptic cytosolic calcium concentration 0
                        negative regulation of calcium import into the mitochondrion 4
                        positive regulation of calcium import into the mitochondrion 0
                        regulation of calcium import into the mitochondrion + 7
paths to the root