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Pathways
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ONTOLOGY REPORT - ANNOTATIONS

Term:interleukin-15-mediated signaling pathway
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Accession:GO:0035723 term browser browse the term
Definition:The series of molecular signals initiated by interleukin-15 binding to its receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription.
Synonyms:exact_synonym: IL-15-mediated signaling pathway;   interleukin-15-mediated signalling pathway


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interleukin-15-mediated signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd4 Cd4 molecule involved_in ISO
IBA		 (PMID:24942581)
GO_REF:0000033		 RGD
GO_Central		 PMID:24942581 GO_REF:0000033 NCBI chr 4:157,668,878...157,695,366 JBrowse link
G Il15 interleukin 15 involved_in ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
(PMID:15123770), (PMID:24942581), (PMID:9097905)		 UniProt
Ensembl
RGD		 PMID:9097905 PMID:15123770 PMID:24942581 GO_REF:0000024 GO_REF:0000107 NCBI chr19:25,640,025...25,706,818
Ensembl chr19:25,640,251...25,706,820 		JBrowse link
G Il15ra interleukin 15 receptor subunit alpha involved_in ISO
IBA		 (PMID:15123770)
GO_REF:0000033		 RGD
GO_Central		 PMID:15123770 GO_REF:0000033 NCBI chr17:66,802,300...66,831,973
Ensembl chr17:66,802,334...66,832,278 		JBrowse link
G Il2rb interleukin 2 receptor subunit beta involved_in IEA
ISS
ISO		 GO_REF:0000107
GO_REF:0000024
(PMID:15123770), (PMID:31040184)		 Ensembl
UniProt
RGD		 PMID:15123770 PMID:31040184 GO_REF:0000024 GO_REF:0000107 NCBI chr 7:110,033,341...110,048,054
Ensembl chr 7:110,033,341...110,048,054 		JBrowse link
G Il2rg interleukin 2 receptor subunit gamma involved_in ISO (PMID:15123770) RGD PMID:15123770 NCBI chr  X:66,395,330...66,399,026
Ensembl chr  X:66,392,542...66,399,823 		JBrowse link
G Jak1 Janus kinase 1 involved_in ISO (PMID:7568001) RGD PMID:7568001 NCBI chr 5:115,780,248...115,888,841
Ensembl chr 5:115,780,248...115,888,926 		JBrowse link
G Jak3 Janus kinase 3 involved_in ISO
IEA		 (PMID:7568001)
GO_REF:0000107		 RGD
Ensembl		 PMID:7568001 GO_REF:0000107 NCBI chr16:18,386,330...18,398,542
Ensembl chr16:18,386,405...18,398,536 		JBrowse link
G Plcb1 phospholipase C beta 1 involved_in ISO
IEA		 (PMID:11743656)
GO_REF:0000107		 RGD
Ensembl		 PMID:11743656 GO_REF:0000107 NCBI chr 3:122,059,988...122,772,896
Ensembl chr 3:122,060,031...122,772,869 		JBrowse link
G Stat3 signal transducer and activator of transcription 3 involved_in ISO
IEA		 (PMID:7568001)
GO_REF:0000107		 RGD
Ensembl		 PMID:7568001 GO_REF:0000107 NCBI chr10:85,811,206...85,863,057
Ensembl chr10:85,811,218...85,863,057 		JBrowse link
G Stat5a signal transducer and activator of transcription 5A involved_in IEA
ISO		 GO_REF:0000107
(PMID:7568001)		 Ensembl
RGD		 PMID:7568001 GO_REF:0000107 NCBI chr10:85,785,537...85,809,869
Ensembl chr10:85,785,537...85,809,866 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19692
    cellular process 18168
      signal transduction 7006
        cell surface receptor signaling pathway 2815
          cytokine-mediated signaling pathway 484
            interleukin-15-mediated signaling pathway 10
Path 2
Term Annotations click to browse term
  biological_process 19692
    response to stimulus 10511
      response to chemical 5851
        response to peptide 1236
          response to cytokine 1212
            cellular response to cytokine stimulus 1076
              cytokine-mediated signaling pathway 484
                interleukin-15-mediated signaling pathway 10
paths to the root