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ONTOLOGY REPORT - ANNOTATIONS

Term:negative regulation of bone mineralization
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Accession:GO:0030502 term browser browse the term
Definition:Any process that stops, prevents, or reduces the frequency, rate or extent of bone mineralization.
Synonyms:exact_synonym: down regulation of bone mineralization;   downregulation of bone mineralization
 narrow_synonym: inhibition of bone mineralization

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negative regulation of bone mineralization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AHSG alpha 2-HS glycoprotein involved_in ISO
IEA		 RGD
Ensembl		 PMID:8702833 GO_REF:0000107 RGD:1626074 NCBI chr15:2,809,234...2,818,382
Ensembl chr15:2,809,028...2,817,514 		JBrowse link
G BCOR BCL6 corepressor involved_in ISO (PMID:19578371) UniProt PMID:19578371 NCBI chr  X:37,191,242...37,319,966
Ensembl chr  X:37,192,874...37,319,782 		JBrowse link
G CCR1 C-C motif chemokine receptor 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr22:7,634,205...7,641,380 JBrowse link
G ECM1 extracellular matrix protein 1 involved_in IEA Ensembl GO_REF:0000107
G ENPP1 ectonucleotide pyrophosphatase/phosphodiesterase 1 involved_in ISO (MGI:5607146|PMID:25479107), (MGI:6220772|PMID:30111653), (MGI:6294341|PMID:22510396) UniProt PMID:22510396 PMID:25479107 PMID:30111653 MGI:5607146 MGI:6220772 MGI:6294341 NCBI chr13:41,670,416...41,755,549 JBrowse link
G FGF23 fibroblast growth factor 23 involved_in ISO (PMID:18282132) UniProt PMID:18282132 NCBI chr11:4,398,318...4,408,415
Ensembl chr11:4,398,675...4,407,209 		JBrowse link
G GATA1 GATA binding protein 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:15005853) Ensembl
MGI		 PMID:15005853 GO_REF:0000107 NCBI chr  X:45,912,638...45,920,415
Ensembl chr  X:45,917,231...45,920,268 		JBrowse link
G GREM1 gremlin 1, DAN family BMP antagonist involved_in ISO (PMID:15539560) BHF-UCL PMID:15539560 NCBI chr26:50,152,097...50,169,760 JBrowse link
G GREM1 gremlin 1, DAN family BMP antagonist involved_in IEA Ensembl GO_REF:0000107 Ensembl chr26:50,155,496...50,156,047 JBrowse link
G HIF1A hypoxia inducible factor 1 subunit alpha involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:17181398) Ensembl
MGI		 PMID:17181398 GO_REF:0000107 NCBI chr24:38,873,830...38,927,657
Ensembl chr24:38,873,861...38,928,288 		JBrowse link
G LOC103242767 C-C motif chemokine 3 involved_in ISO (PMID:21403648) UniProt PMID:21403648 NCBI chr16:29,887,799...29,897,664
Ensembl chr16:29,887,883...29,897,544 		JBrowse link
G LTBP3 latent transforming growth factor beta binding protein 3 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:11790802) Ensembl
MGI		 PMID:11790802 GO_REF:0000107 NCBI chr 1:8,681,140...8,700,721
Ensembl chr 1:8,681,156...8,703,740 		JBrowse link
G MEPE matrix extracellular phosphoglycoprotein acts_upstream_of_or_within ISO (PMID:12421822), (PMID:15843468)
(PMID:22766095)		 MGI PMID:12421822 PMID:15843468 PMID:22766095 NCBI chr 7:36,201,916...36,216,446 JBrowse link
G NFE2 nuclear factor, erythroid 2 acts_upstream_of_or_within ISO (PMID:15005853) MGI PMID:15005853 NCBI chr11:50,409,023...50,417,931
Ensembl chr11:50,408,984...50,417,863 		JBrowse link
G PTK2B protein tyrosine kinase 2 beta involved_in IEA Ensembl GO_REF:0000107 NCBI chr 8:25,437,680...25,571,594
Ensembl chr 8:25,437,564...25,571,782 		JBrowse link
G SOX9 SRY-box transcription factor 9 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:11371614) Ensembl
MGI		 PMID:11371614 GO_REF:0000107 NCBI chr16:49,519,749...49,523,967
Ensembl chr16:49,518,185...49,523,898 		JBrowse link
G SRGN serglycin involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:62,217,836...62,235,110
Ensembl chr 9:62,217,525...62,235,238 		JBrowse link
G TRPM4 transient receptor potential cation channel subfamily M member 4 ISO RGD PMID:23081848 RGD:10003033 NCBI chr 6:42,379,534...42,424,721
Ensembl chr 6:42,379,659...42,424,146 		JBrowse link
negative regulation of bone mineralization involved in bone maturation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GREM1 gremlin 1, DAN family BMP antagonist involved_in ISO (PMID:15539560) BHF-UCL PMID:15539560 NCBI chr26:50,152,097...50,169,760 JBrowse link
G GREM1 gremlin 1, DAN family BMP antagonist involved_in IEA Ensembl GO_REF:0000107 Ensembl chr26:50,155,496...50,156,047 JBrowse link
G LOC103239345 refilin-A involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:24436304) Ensembl
MGI		 PMID:24436304 GO_REF:0000107 NCBI chr11:119,497,097...119,666,178
Ensembl chr11:119,647,606...119,668,003 		JBrowse link
G PTH parathyroid hormone involved_in ISO PMID:11604398 CAFA PMID:11604398 RGD:12793028 NCBI chr 1:51,327,555...51,330,810 JBrowse link
G RFLNB refilin B involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:24436304) Ensembl
MGI		 PMID:24436304 GO_REF:0000107 NCBI chr16:269,395...278,249
Ensembl chr16:271,418...278,115 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 16523
    negative regulation of biological process 5431
      negative regulation of multicellular organismal process 1251
        negative regulation of ossification 48
          negative regulation of bone mineralization 21
            negative regulation of bone mineralization involved in bone maturation 5
Path 2
Term Annotations click to browse term
  biological_process 16523
    developmental process 6548
      anatomical structure development 6163
        tissue development 2175
          biomineral tissue development 190
            bone mineralization 145
              regulation of bone mineralization 88
                negative regulation of bone mineralization 21
                  negative regulation of bone mineralization involved in bone maturation 5
paths to the root