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ONTOLOGY REPORT - ANNOTATIONS


Term:aminoacyl-tRNA editing activity
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Accession:GO:0002161 term browser browse the term
Definition:The hydrolysis of an incorrectly aminoacylated tRNA.
Synonyms:related_synonym: amino acid proofreading activity;   aminoacyl-tRNA hydrolysis activity



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aminoacyl-tRNA editing activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aars1 alanyl-tRNA synthetase 1 enables ISS
IBA
ISO
GO_REF:0000024
GO_REF:0000033
(MGI:4457227|PMID:20010690)
(PMID:28493438)
UniProt
GO_Central
RGD
PMID:20010690 PMID:28493438 GO_REF:0000024 GO_REF:0000033 MGI:4457227 NCBI chr19:38,999,130...39,021,152
Ensembl chr19:38,999,163...39,021,147
JBrowse link
G Aars2 alanyl-tRNA synthetase 2, mitochondrial enables IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 9:15,484,639...15,496,116
Ensembl chr 9:15,297,531...15,496,090
JBrowse link
G Aarsd1 alanyl-tRNA synthetase domain containing 1 enables ISO (MGI:5486548|PMID:18172502) RGD PMID:18172502 MGI:5486548 NCBI chr10:86,340,625...86,353,732
Ensembl chr10:86,340,626...86,353,729
JBrowse link
G Iars1 isoleucyl-tRNA synthetase 1 enables IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr17:14,940,919...14,987,277
Ensembl chr17:14,940,924...14,987,237
JBrowse link
G Iars2 isoleucyl-tRNA synthetase 2, mitochondrial enables IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr13:96,831,484...96,865,518
Ensembl chr13:96,831,484...96,865,501
JBrowse link
G Lars1 leucyl-tRNA synthetase 1 enables ISO (PMID:25051973) RGD PMID:25051973 NCBI chr18:34,201,555...34,256,003
Ensembl chr18:34,201,549...34,255,931
JBrowse link
G Lars2 leucyl-tRNA synthetase 2, mitochondrial enables IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 8:123,010,271...123,106,395
Ensembl chr 8:123,010,293...123,106,395
JBrowse link
G Prorsd1 prolyl-tRNA synthetase associated domain containing 1 enables IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr14:103,257,979...103,260,248
Ensembl chr14:103,257,979...103,260,248
JBrowse link
G Tars2 threonyl-tRNA synthetase 2, mitochondrial enables ISO
ISS
(PMID:26811336)
GO_REF:0000024
RGD
UniProt
PMID:26811336 GO_REF:0000024 NCBI chr 2:183,293,095...183,310,210
Ensembl chr 2:183,293,097...183,310,184
JBrowse link
G Vars1 valyl-tRNA synthetase 1 enables IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr20:3,805,774...3,820,468
Ensembl chr20:3,805,776...3,820,298
JBrowse link
G Vars2 valyl-tRNA synthetase 2, mitochondrial enables IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr20:3,077,132...3,087,994
Ensembl chr20:3,077,132...3,087,994
JBrowse link
Ala-tRNA(Thr) hydrolase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dtd2 D-aminoacyl-tRNA deacylase 2 enables ISO (PMID:29410408)
(MGI:6148359|PMID:29410408)
RGD PMID:29410408 MGI:6148359 NCBI chr 6:69,450,146...69,456,430
Ensembl chr 6:69,449,614...69,456,427
JBrowse link
D-tyrosyl-tRNA(Tyr) deacylase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dtd1 D-aminoacyl-tRNA deacylase 1 enables IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 3:131,995,870...132,158,646
Ensembl chr 3:131,995,861...132,158,659
JBrowse link
G Dtd2 D-aminoacyl-tRNA deacylase 2 enables ISO
IBA
(MGI:6148359|PMID:29410408)
GO_REF:0000033
RGD
GO_Central
PMID:29410408 GO_REF:0000033 MGI:6148359 NCBI chr 6:69,450,146...69,456,430
Ensembl chr 6:69,449,614...69,456,427
JBrowse link
Ser-tRNA(Ala) hydrolase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aars1 alanyl-tRNA synthetase 1 enables ISO
ISS
(MGI:3640843|PMID:16906134), (MGI:5609717|PMID:25422440), (MGI:6159204|PMID:29769718), (PMID:25422440)
GO_REF:0000024
RGD
UniProt
PMID:16906134 PMID:25422440 PMID:29769718 GO_REF:0000024 MGI:3640843 MGI:5609717 MGI:6159204 NCBI chr19:38,999,130...39,021,152
Ensembl chr19:38,999,163...39,021,147
JBrowse link
G Aarsd1 alanyl-tRNA synthetase domain containing 1 enables IBA
ISO
GO_REF:0000033
(PMID:21285375)
GO_Central
RGD
PMID:21285375 GO_REF:0000033 NCBI chr10:86,340,625...86,353,732
Ensembl chr10:86,340,626...86,353,729
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  molecular_function 20483
    catalytic activity 6036
      catalytic activity, acting on a nucleic acid 630
        catalytic activity, acting on RNA 396
          catalytic activity, acting on a tRNA 136
            aminoacyl-tRNA editing activity 13
              Ala-tRNA(Pro) hydrolase activity 0
              Ala-tRNA(Thr) hydrolase activity 1
              Cys-tRNA(Pro) hydrolase activity 0
              D-aminoacyl-tRNA deacylase activity + 2
              Gly-tRNA(Ala) hydrolase activity 0
              Ser-tRNA(Ala) hydrolase activity 2
paths to the root