CHEBI ONTOLOGY - ANNOTATIONS
The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/ . The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/ ). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term: Xanthorrhizol
Accession: CHEBI:184290
browse the term
Synonyms: exact_synonym: 2-methyl-5-[(2R)-6-methylhept-5-en-2-yl]phenol
related_synonym: Formula=C15H22O; InChI=1S/C15H22O/c1-11(2)6-5-7-12(3)14-9-8-13(4)15(16)10-14/h6,8-10,12,16H,5,7H2,1-4H3/t12-/m1/s1; InChIKey=FKWGCEDRLNNZOZ-GFCCVEGCSA-N; SMILES=OC=1C=C([C@@H](CCC=C(C)C)C)C=CC1C
xref: CAS:30199-26-9; Chemspider:84081
xref_mesh: MESH:C120248
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Bad
BCL2-associated agonist of cell death
increases expression
ISO
xanthorrhizol results in increased expression of BAD protein
CTD
PMID:34664399
NCBI chr 1:204,133,502...204,142,829
Ensembl chr 1:204,131,501...204,142,823
G
Bax
BCL2 associated X, apoptosis regulator
increases expression
ISO
xanthorrhizol results in increased expression of BAX protein
CTD
PMID:34664399
NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368
G
Bcl2
BCL2, apoptosis regulator
decreases expression
ISO
xanthorrhizol results in decreased expression of BCL2 protein
CTD
PMID:34664399
NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743 Ensembl chr13:22,684,989...22,853,743
G
Bcl2l1
Bcl2-like 1
decreases expression
ISO
xanthorrhizol results in decreased expression of BCL2L1 protein
CTD
PMID:34664399
NCBI chr 3:141,253,508...141,304,582
Ensembl chr 3:141,253,523...141,303,479
G
Casp3
caspase 3
multiple interactions
ISO
benzoylcarbonyl-aspartyl-glutamyl-valyl-aspartyl-fluoromethyl ketone inhibits the reaction [xanthorrhizol results in increased expression of and results in increased activity of CASP3 protein]; xanthorrhizol results in increased expression of and results in increased activity of CASP3 protein
CTD
PMID:34664399
NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
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Casp9
caspase 9
increases activity
ISO
xanthorrhizol results in increased activity of CASP9 protein
CTD
PMID:34664399
NCBI chr 5:154,108,872...154,126,628
Ensembl chr 5:154,109,046...154,126,626
G
Chuk
component of inhibitor of nuclear factor kappa B kinase complex
decreases expression
ISO
xanthorrhizol results in decreased expression of CHUK protein
CTD
PMID:34664399
NCBI chr 1:242,959,539...242,995,066
Ensembl chr 1:242,959,760...242,995,065
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Cycs
cytochrome c, somatic
increases expression
ISO
xanthorrhizol results in increased expression of CYCS protein
CTD
PMID:34664399
NCBI chr 4:79,651,894...79,653,994
Ensembl chr 4:79,651,378...79,654,054 Ensembl chr18:79,651,378...79,654,054
G
Nfkbia
NFKB inhibitor alpha
increases expression
ISO
xanthorrhizol results in increased expression of NFKBIA protein
CTD
PMID:34664399
NCBI chr 6:72,858,713...72,861,941
Ensembl chr 6:72,858,712...72,861,941
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