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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:drimane
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Accession:CHEBI:36474 term browser browse the term
Definition:A terpenoid fundamental parent that has formula C15H28.
Synonyms:related_synonym: (4aR,5S,6S,8aS)-1,1,4a,5,6-pentamethyldecahydronaphthalene;   Formula=C15H28;   InChI=1S/C15H28/c1-11-7-8-13-14(3,4)9-6-10-15(13,5)12(11)2/h11-13H,6-10H2,1-5H3/t11-,12-,13-,15+/m0/s1;   InChIKey=CVRSZZJUWRLRDE-PWNZVWSESA-N;   SMILES=[H][C@@]12CC[C@H](C)[C@H](C)[C@@]1(C)CCCC2(C)C
 xref: Beilstein:2959385


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(+)-albicanol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CASP3 caspase 3 multiple interactions ISO albicanol inhibits the reaction [Galactose results in increased expression of CASP3 mRNA] CTD PMID:33761044 NCBI chr 4:184,627,696...184,649,447
Ensembl chr 4:184,627,696...184,650,062 		JBrowse link
G CASP9 caspase 9 multiple interactions ISO albicanol inhibits the reaction [Galactose results in increased expression of CASP9 mRNA] CTD PMID:33761044 NCBI chr 1:15,491,401...15,524,912
Ensembl chr 1:15,490,832...15,526,534 		JBrowse link
G CAT catalase multiple interactions ISO albicanol inhibits the reaction [Galactose results in decreased activity of CAT protein] CTD PMID:33761044 NCBI chr11:34,438,934...34,472,060
Ensembl chr11:34,438,934...34,472,060 		JBrowse link
G HMOX1 heme oxygenase 1 multiple interactions ISO albicanol inhibits the reaction [Galactose results in decreased expression of HMOX1 protein] CTD PMID:33761044 NCBI chr22:35,381,096...35,394,207
Ensembl chr22:35,380,361...35,394,214 		JBrowse link
G IL1B interleukin 1 beta multiple interactions ISO albicanol inhibits the reaction [Galactose results in increased expression of IL1B mRNA] CTD PMID:33761044 NCBI chr 2:112,829,751...112,836,779
Ensembl chr 2:112,829,751...112,836,816 		JBrowse link
G KEAP1 kelch like ECH associated protein 1 multiple interactions ISO albicanol inhibits the reaction [Galactose results in increased expression of KEAP1 mRNA]; albicanol inhibits the reaction [Galactose results in increased expression of KEAP1 protein] CTD PMID:33761044 NCBI chr19:10,486,125...10,503,356
Ensembl chr19:10,486,125...10,503,558 		JBrowse link
G NFE2L2 NFE2 like bZIP transcription factor 2 multiple interactions ISO albicanol inhibits the reaction [Galactose results in decreased expression of NFE2L2 mRNA]; albicanol inhibits the reaction [Galactose results in decreased expression of NFE2L2 protein] CTD PMID:33761044 NCBI chr 2:177,230,303...177,264,727
Ensembl chr 2:177,218,667...177,392,756 		JBrowse link
G NQO1 NAD(P)H quinone dehydrogenase 1 multiple interactions ISO albicanol inhibits the reaction [Galactose results in decreased expression of NQO1 protein] CTD PMID:33761044 NCBI chr16:69,709,401...69,726,560
Ensembl chr16:69,706,996...69,726,668 		JBrowse link
G SOD2 superoxide dismutase 2 multiple interactions ISO albicanol inhibits the reaction [Galactose results in decreased expression of SOD2 protein] CTD PMID:33761044 NCBI chr 6:159,669,069...159,762,281
Ensembl chr 6:159,669,069...159,762,529 		JBrowse link
G TNF tumor necrosis factor multiple interactions ISO albicanol inhibits the reaction [Galactose results in increased expression of TNF mRNA] CTD PMID:33761044 NCBI chr 6:31,575,565...31,578,336
Ensembl chr 6:31,575,565...31,578,336 		JBrowse link
drimenol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BAX BCL2 associated X, apoptosis regulator increases expression EXP drimenol results in increased expression of BAX protein CTD PMID:30935903 NCBI chr19:48,954,875...48,961,798
Ensembl chr19:48,954,815...48,961,798 		JBrowse link
G BCL2 BCL2 apoptosis regulator decreases expression EXP drimenol results in decreased expression of BCL2 protein CTD PMID:30935903 NCBI chr18:63,123,346...63,320,090
Ensembl chr18:63,123,346...63,320,128 		JBrowse link
G CASP3 caspase 3 increases activity EXP drimenol results in increased activity of CASP3 protein CTD PMID:30935903 NCBI chr 4:184,627,696...184,649,447
Ensembl chr 4:184,627,696...184,650,062 		JBrowse link
G CASP9 caspase 9 increases cleavage EXP drimenol results in increased cleavage of CASP9 protein CTD PMID:30935903 NCBI chr 1:15,491,401...15,524,912
Ensembl chr 1:15,490,832...15,526,534 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 26504
    chemical entity 26484
      atom 26480
        nonmetal atom 25742
          carbon atom 25624
            organic molecular entity 25624
              organic fundamental parent 22044
                natural product fundamental parent 16230
                  terpenoid fundamental parent 4058
                    drimane 12
                      (+)-albicanol 10
                      drimendiol 0
                      drimenol + 4
Path 2
Term Annotations click to browse term
  CHEBI ontology 26504
    subatomic particle 26480
      composite particle 26480
        hadron 26480
          baryon 26480
            nucleon 26480
              atomic nucleus 26480
                atom 26480
                  main group element atom 26217
                    main group molecular entity 26217
                      s-block molecular entity 25454
                        hydrogen molecular entity 24861
                          hydrides 23080
                            organic hydride 22044
                              organic fundamental parent 22044
                                hydrocarbon 21482
                                  terpene 14726
                                    sesquiterpene 3376
                                      drimane 12
                                        (+)-albicanol 10
                                        drimendiol 0
                                        drimenol + 4
paths to the root