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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:buserelin
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Accession:CHEBI:135907 term browser browse the term
Synonyms:related_synonym: Formula=C60H86N16O13;   InChI=1S/C60H86N16O13/c1-7-64-57(87)48-15-11-23-76(48)58(88)41(14-10-22-65-59(61)62)69-51(81)42(24-33(2)3)70-56(86)47(31-89-60(4,5)6)75-52(82)43(25-34-16-18-37(78)19-17-34)71-55(85)46(30-77)74-53(83)44(26-35-28-66-39-13-9-8-12-38(35)39)72-54(84)45(27-36-29-63-32-67-36)73-50(80)40-20-21-49(79)68-40/h8-9,12-13,16-19,28-29,32-33,40-48,66,77-78H,7,10-11,14-15,20-27,30-31H2,1-6H3,(H,63,67)(H,64,87)(H,68,79)(H,69,81)(H,70,86)(H,71,85)(H,72,84)(H,73,80)(H,74,83)(H,75,82)(H4,61,62,65)/t40-,41-,42-,43-,44-,45-,46-,47+,48-/m0/s1;   InChIKey=CUWODFFVMXJOKD-UVLQAERKSA-N;   SMILES=C([C@H](NC([C@H](CC1=CNC=N1)NC(=O)[C@@H]2CCC(N2)=O)=O)C(N[C@H](C(N[C@@H](CC3=CC=C(C=C3)O)C(N[C@@H](C(N[C@H](C(N[C@H](C(=O)N4[C@H](C(NCC)=O)CCC4)CCCNC(=N)N)=O)CC(C)C)=O)COC(C)(C)C)=O)=O)CO)=O)C=5C6=C(NC5)C=CC=C6;   etilamide;   receptal
 xref: CAS:57982-77-1;   Drug_Central:436
 xref_mesh: MESH:D002064


show annotations for term's descendants           Sort by:
buserelin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcc3 ATP binding cassette subfamily C member 3 multiple interactions ISO [Buserelin co-treated with CGB3 protein] results in increased expression of ABCC3 mRNA CTD PMID:19955106 NCBI chr10:79,793,571...79,839,528
Ensembl chr10:79,296,693...79,342,595 		JBrowse link
G Ahnak2 AHNAK nucleoprotein 2 multiple interactions ISO [Buserelin co-treated with CGB3 protein] results in increased expression of AHNAK2 mRNA CTD PMID:19955106 NCBI chr 6:131,830,668...131,876,311
Ensembl chr 6:131,831,454...131,854,463 		JBrowse link
G Bax BCL2 associated X, apoptosis regulator increases expression ISO Buserelin results in increased expression of BAX protein CTD PMID:15965100 NCBI chr 1:105,076,472...105,081,906
Ensembl chr 1:95,938,808...95,945,368 		JBrowse link
G Casp3 caspase 3 increases expression ISO Buserelin results in increased expression of CASP3 protein CTD PMID:15965100 NCBI chr16:52,395,539...52,413,794
Ensembl chr16:45,662,910...45,684,648 		JBrowse link
G Casp9 caspase 9 increases expression ISO Buserelin results in increased expression of CASP9 protein CTD PMID:15965100 Ensembl chr 5:154,109,046...154,126,626 JBrowse link
G Cycs cytochrome c, somatic affects localization ISO Buserelin affects the localization of CYCS protein CTD PMID:15965100 NCBI chr 4:80,982,667...80,984,767
Ensembl chr 4:79,651,378...79,654,054
Ensembl chr18:79,651,378...79,654,054 		JBrowse link
G Dkk1 dickkopf WNT signaling pathway inhibitor 1 multiple interactions ISO [Buserelin co-treated with CGB3 protein] results in increased expression of DKK1 mRNA; [Buserelin co-treated with CGB3 protein] results in increased expression of DKK1 protein CTD PMID:19955106 NCBI chr 1:237,794,969...237,798,650
Ensembl chr 1:228,381,521...228,385,202 		JBrowse link
G Dkk2 dickkopf WNT signaling pathway inhibitor 2 multiple interactions ISO [Buserelin co-treated with CGB3 protein] results in decreased expression of DKK2 mRNA CTD PMID:19955106 NCBI chr 2:220,568,338...220,660,225
Ensembl chr 2:220,568,338...220,660,225 		JBrowse link
G Fshb follicle stimulating hormone subunit beta multiple interactions ISO Buserelin inhibits the reaction [Doxorubicin inhibits the reaction [FSHB protein results in increased chemical synthesis of Estradiol]] CTD PMID:17028438 NCBI chr 3:114,003,262...114,007,072
Ensembl chr 3:93,548,560...93,552,370 		JBrowse link
G Gnrhr gonadotropin releasing hormone receptor multiple interactions ISO Buserelin binds to and results in increased activity of GNRHR protein; Buserelin inhibits the reaction [GNRHR protein results in increased transport of deslorelin] CTD PMID:15212170 NCBI chr14:21,856,871...21,874,861
Ensembl chr14:21,856,871...21,874,861 		JBrowse link
G Muc16 mucin 16, cell surface associated multiple interactions ISO [Buserelin co-treated with CGB3 protein] results in increased expression of MUC16 mRNA CTD PMID:19955106 NCBI chr 8:16,164,531...16,323,126 JBrowse link
G Sfrp4 secreted frizzled-related protein 4 multiple interactions ISO [Buserelin co-treated with CGB3 protein] results in decreased expression of SFRP4 mRNA CTD PMID:19955106 NCBI chr17:45,278,867...45,330,806
Ensembl chr17:45,234,097...45,330,736 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19899
    chemical entity 19897
      group 19849
        organic group 19011
          amino-acid residue 11452
            peptide 11452
              oligopeptide 1361
                buserelin 12
Path 2
Term Annotations click to browse term
  CHEBI ontology 19899
    subatomic particle 19897
      composite particle 19897
        hadron 19897
          baryon 19897
            nucleon 19897
              atomic nucleus 19897
                atom 19897
                  main group element atom 19836
                    p-block element atom 19836
                      carbon group element atom 19776
                        carbon atom 19772
                          organic molecular entity 19772
                            heteroorganic entity 19536
                              organochalcogen compound 19296
                                organooxygen compound 19214
                                  carbon oxoacid 18693
                                    carboxylic acid 18690
                                      carboacyl group 17731
                                        univalent carboacyl group 17731
                                          carbamoyl group 17576
                                            carboxamide 17576
                                              peptide 11452
                                                oligopeptide 1361
                                                  buserelin 12
paths to the root