Gene:	Kcnj11 ( Rattus norvegicus ) potassium inwardly rectifying channel, subfamily J, member 11
Description:	an ATP-sensitive K+ channel
Synonyms:	Kir6.2; potassium inwardly-rectifying channel subfamily J member 11;
ArrayIDs:	1391007_s_at; 5893237; D86039_at; 1369782_a_at; D86039_g_at; 1387698_at; rc_AI044326_i_at; 6155584;  (details...)
Gene Type:	protein-coding
Additional Data
Homologs
Homo sapiens: KCNJ11     See the Human gene in context in:     UCSC     NCBI MapViewer
Mus musculus: Kcnj11     See the Mouse gene in context in:     UCSC     NCBI MapViewer
Comparative Map Data Species Symbol Map Name Chr. Position Rattus norvegicus Kcnj11 genome assembly 3.1 1 96693070 - 96696104     Rat Celera Assembly 1 90842071 - 90845104     RGSC genome assembly v3.4 1 96614960 - 96617993     Cytogenetic 1 q22 Mus musculus Kcnj11 Mouse genome assembly build 36.1 7 53352532 - 53355607     Cytogenetic 7 7 B4 Homo sapiens KCNJ11 human genome assembly 11 17364788 - 17366737     Human genome assembly build 36.2 11 17363371 - 17366782     Cytogenetic 11 p15.1   View comparative maps:      NCBI MapViewer
Genome
View:
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Annotation
Molecular Function	Gene Ontology potassium ion binding,  voltage-gated ion channel activity,  ATP binding ...  (details...)
Biological Process	Gene Ontology potassium ion import,  response to drug,  response to ATP ...  (details...)
Cellular Component	Gene Ontology mitochondrion,  ATP-sensitive potassium channel complex,  integral to membrane ...  (details...)
Disease	Ontology Parkinsonian Disorders,  Hypertension,  Diabetes Mellitus ...  (details...)
Expression	Note Reference expressed in vascular smooth muscle cells 724755
Pathway	Ontology altered insulin secretion pathway,  type 2 diabetes mellitus pathway,  insulin secretion pathway (details...)
External Links
Databases	DATABASE ID SOURCE UNIPARC: UPI000012D8AB IPI KEGG Report: rno:83535 ENTREZGENE HomoloGene Group ID: 441 ENTREZGENE Germonline: 69247 Pfam: IRK IPI KEGG Pathway: 04930 ENTREZGENE InterPro: K_chnl_inward-rec_Kir6.2. IPI InterPro: K_chnl_inward-rec_Kir_Cr2. IPI InterPro: K_chnl_inward-rec_Kir_cyto. IPI InterPro: K_chnl_inward-rec_Kir-like. IPI InterPro: Ig_E-set. IPI InterPro: K_chnl_inward-rec_Kir. IPI IPI: IPI00190663 IPI Ensembl Protein: ENSRNOP00000028685 IPI Gene3D-CATH: IR_K+channel_cytopl IPI Entrez Gene: Kcnj11 ENTREZGENE PIRSF: GIRK_kir IPI TIGR: TC216683 UniProt: IRK11_RAT IPI Ensembl Genes: ENSRNOG00000021128 IPI Superfamily-SCOP: Ig_E-set IPI PANTHER: K+channel_IR IPI PRINTS: KIRCHANNEL. IPI PRINTS: KIR62CHANNEL. IPI
Sequences	Nucleotide: BF565039 Get FASTA Search GEO Profiles Nucleotide: AW527189 Get FASTA Search GEO Profiles Nucleotide: D61687 Get FASTA Search GEO Profiles Nucleotide: AB043638 Get FASTA Search GEO Profiles Nucleotide: U44897 Get FASTA Search GEO Profiles Nucleotide: CH473979 Get FASTA Search GEO Profiles Nucleotide: X97041 Get FASTA Search GEO Profiles Nucleotide: NM_031358 Get FASTA Search GEO Profiles (View all 8 Nucleotide Accessions) Protein: BAA23630 Get FASTA Protein: EDM07273 Get FASTA Protein: AAB01810 Get FASTA Protein: NP_112648 Get FASTA Protein: BAA96239 Get FASTA Protein: P70673 Get FASTA Protein: CAA65754 Get FASTA (View all 7 Protein Accessions)
Clusters	UniGene: 3985
References
Curated References	33 references in RGD related to Kcnj11
Other References	36 other references at PubMed related to Kcnj11
Database Information
RGD ID	69247
History	Date Current Symbol Current Name Previous Symbol Previous name Status Description Reference 30-MAR-06: Kcnj11 potassium inwardly rectifying channel, subfamily J, member 11 APPROVED Symbol and Name status set to approved 1299863 25-JUL-02: Kir6.2 potassium inwardly rectifying channel, subfamily J, member 11 WITHDRAWN gene retired, merged with Kcnj11 (RGD:69247) 61033 10-JUN-02: Kcnj11 potassium inwardly rectifying channel, subfamily J, member 11 APPROVED Name updated 70584