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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 69247 Species: Rattus norvegicus RGD Object: Gene Symbol: Kcnj11 Name: potassium inwardly rectifying channel, subfamily J, member 11

Acc ID: CHEBI:26216 Term: potassium atom Definition: An alkali metal atom that has formula K. CasRN: 7440-09-7 Chemical ID: MESH:D011188

Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.

Qualifier	Evidence	With	Reference	Source	Notes	Original Reference(s)
multiple interactions	ISO	RGD:69099	6480464	CTD	2,4-Dinitrophenol promotes the reaction [KCNJ11 protein results in increased transport of Potassium] Glyburide inhibits the reaction [2,4-Dinitrophenol promotes the reaction [KCNJ11 protein results in increased transport of Potassium]]	PMID:15949470
multiple interactions	ISO	RGD:69099	6480464	CTD	Pinacidil promotes the reaction [KCNJ11 protein results in increased transport of Potassium]	PMID:18420708
increases transport	ISO	RGD:69099	6480464	CTD	KCNJ11 protein results in increased transport of Potassium	PMID:10022826 PMID:15949470 PMID:18420708
increases transport	ISO	RGD:69099	6480464	CTD	KCNJ11 protein results in increased transport of Potassium	PMID:15949470 PMID:18420708 PMID:10022826
increases transport	ISO	RGD:69099	6480464	CTD	KCNJ11 protein results in increased transport of Potassium	PMID:18420708 PMID:10022826 PMID:15949470
increases transport	ISO	RGD:69099	6480464	CTD	KCNJ11 protein results in increased transport of Potassium	PMID:10022826 PMID:18420708 PMID:15949470