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GENE - TERM ANNOTATION REPORT

2 Annotations Found.

An association has been curated linking Kcnj11 and altered insulin secretion pathway in Rattus norvegicus.        

The association was inferred from sequence or structural similarity (ISS)
The annotation was made from Florez JC, etal., Diabetes. 2007 Feb;56(2):531-6.
The annotation has been inferred from KCNJ11 (Homo sapiens)
17 additional annotations were made from Florez JC, etal., Diabetes. 2007 Feb;56(2):531-6.
3 RGD objects have been annotated to altered insulin secretion pathway  (PW:0000677)
38 papers in RGD have been used to annotate Kcnj11
Curation Notes: DNA:missense mutation::p.E23K (human)

This annotation was curated on 2011-06-28 11:58:10.0 by RGD curator number 20. For more information contact us

An association has been curated linking Kcnj11 and altered insulin secretion pathway in Rattus norvegicus.        

The association was inferred from sequence or structural similarity (ISS)
The annotation was made from Riedel MJ, etal., Hum Genet. 2005 Feb;116(3):133-45. Epub 2004 Nov 23.
The annotation has been inferred from KCNJ11 (Homo sapiens)
8 additional annotations were made from Riedel MJ, etal., Hum Genet. 2005 Feb;116(3):133-45. Epub 2004 Nov 23.
3 RGD objects have been annotated to altered insulin secretion pathway  (PW:0000677)
38 papers in RGD have been used to annotate Kcnj11
Curation Notes: polymorphisms in the human gene are linked to altered insulin secretion; E23K polymorphism appears to confer susceptibility to diabetes type-2 in Caucasian population

This annotation was curated on 2009-10-05 09:35:00.0 by RGD curator number 20. For more information contact us

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