pyrrolidinecarboxamide - Ontology Report - Rat Genome Database

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CHEBI ONTOLOGY - ANNOTATIONS

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The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:	pyrrolidinecarboxamide	go back to main search page
Accession:	CHEBI:46770	browse the term
Synonyms:	related_synonym:	pyrrolidinecarboxamides

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Rat (42) Mouse (41) Human (42) Chinchilla (0) Bonobo (0) Dog (0) Squirrel (0) Pig (0) Green Monkey (0) Naked Mole-rat (0) All
Genes (42)

acalabrutinib

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

C-reactive protein

affects expression

acalabrutinib affects the expression of CRP protein

NCBI chr13:85,135,384...85,175,178
Ensembl chr13:85,124,977...85,175,178

G

cytochrome P450, family 3, subfamily a, polypeptide 2

increases metabolic processing
multiple interactions
affects metabolic processing

CYP3A4 protein results in increased metabolism of acalabrutinib
Ketoconazole affects the reaction [CYP3A4 protein alternative form affects the metabolism of acalabrutinib]

NCBI chr12:9,207,978...9,230,064
Ensembl chr12:9,015,383...9,285,008

G

interleukin 6

decreases expression

acalabrutinib results in decreased expression of IL6 protein

NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178

clindamycin

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

cytochrome P450, family 3, subfamily a, polypeptide 2

multiple interactions
increases expression

Clindamycin results in increased expression of and results in increased activity of CYP3A4 protein
Clindamycin results in increased expression of CYP3A4 mRNA

NCBI chr12:9,207,978...9,230,064
Ensembl chr12:9,015,383...9,285,008

G

matrix metallopeptidase 13

increases expression

Clindamycin results in increased expression of MMP13 mRNA

NCBI chr 8:4,497,960...4,508,239
Ensembl chr 8:4,497,960...4,508,239

G

RT1 class Ia, locus A2

affects expression

Clindamycin affects the expression of HLA-E mRNA

NCBI chr20:4,870,939...4,910,183

G

RT1 class II, locus Db1

affects expression

Clindamycin affects the expression of HLA-DRB1 mRNA

NCBI chr20:4,548,664...4,558,237
Ensembl chr20:4,548,666...4,558,258

clindamycin phosphate

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

paraoxonase 1

decreases activity

clindamycin phosphate results in decreased activity of PON1 protein

NCBI chr 4:33,294,737...33,325,759
Ensembl chr 4:33,294,722...33,321,360

lincomycin

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

major histocompatibility complex, class I-related

affects expression

Lincomycin affects the expression of MR1 mRNA

NCBI chr13:67,298,362...67,317,985
Ensembl chr13:67,299,585...67,317,970

G

RT1 class Ia, locus A2

affects expression

Lincomycin affects the expression of HLA-E mRNA

NCBI chr20:4,870,939...4,910,183

meropenem

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

RT1 class II, locus DOb

affects expression

meropenem affects the expression of HLA-DOB mRNA

NCBI chr20:4,619,418...4,625,627
Ensembl chr20:4,619,816...4,625,667

G

RT1 class Ib, locus M3, gene 1

affects expression

Meropenem affects the expression of HLA-G mRNA

NCBI chr20:1,323,976...1,328,126
Ensembl chr20:1,287,521...1,328,117

SCH772984

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

actin alpha 2, smooth muscle

multiple interactions

SCH772984 inhibits the reaction [TGFB1 protein results in increased expression of ACTA2 protein]

NCBI chr 1:231,746,527...231,759,307
Ensembl chr 1:231,746,548...231,759,554

G

adrenomedullin

decreases secretion
multiple interactions

SCH772984 results in decreased secretion of ADM protein
SCH772984 inhibits the reaction [diphenylarsinic acid results in increased secretion of ADM protein]

NCBI chr 1:164,745,484...164,747,655
Ensembl chr 1:164,745,466...164,747,654

G

amyloid beta precursor protein

multiple interactions

SCH772984 inhibits the reaction [APP protein modified form results in increased expression of GRK2 protein]

NCBI chr11:24,019,774...24,236,584
Ensembl chr11:24,019,778...24,236,561

G

BCL2, apoptosis regulator

multiple interactions

SCH772984 inhibits the reaction [pachastrissamine analog inhibits the reaction [BCL2 protein binds to BECN1 protein]]

NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743
Ensembl chr13:22,684,989...22,853,743

G

Bcl2-like 1

multiple interactions

SCH772984 inhibits the reaction [pachastrissamine analog inhibits the reaction [BCL2L1 protein binds to BECN1 protein]]

NCBI chr 3:141,253,508...141,304,582
Ensembl chr 3:141,253,523...141,303,479

G

beclin 1

multiple interactions

SCH772984 inhibits the reaction [pachastrissamine analog inhibits the reaction [BCL2 protein binds to BECN1 protein]]; SCH772984 inhibits the reaction [pachastrissamine analog inhibits the reaction [BCL2L1 protein binds to BECN1 protein]]

NCBI chr10:86,231,387...86,246,742
Ensembl chr10:86,231,388...86,246,742

G

C-C motif chemokine ligand 2

multiple interactions

SCH772984 inhibits the reaction [diphenylarsinic acid results in increased secretion of CCL2 protein]

NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226

G

cAMP responsive element binding protein 1

multiple interactions

SCH772984 inhibits the reaction [diphenylarsinic acid results in increased phosphorylation of and results in increased expression of CREB1 protein]; SCH772984 results in decreased phosphorylation of and results in decreased expression of CREB1 protein

NCBI chr 9:65,903,511...65,972,562
Ensembl chr 9:65,903,547...65,970,816

G

C-X-C motif chemokine ligand 1

multiple interactions

SCH772984 inhibits the reaction [diphenylarsinic acid results in increased secretion of CXCL1 protein]

NCBI chr14:17,193,364...17,195,143
Ensembl chr14:17,193,365...17,195,215

G

cytochrome P450, family 2, subfamily e, polypeptide 1

multiple interactions

SCH772984 inhibits the reaction [Ethylene Chlorohydrin results in increased expression of CYP2E1 mRNA]; SCH772984 inhibits the reaction [Ethylene Chlorohydrin results in increased expression of CYP2E1 protein]

NCBI chr 1:195,840,330...195,850,728
Ensembl chr 1:195,840,058...195,864,023

G

fibroblast growth factor 2

multiple interactions
increases secretion

SCH772984 promotes the reaction [diphenylarsinic acid results in increased secretion of FGF2 protein]
SCH772984 results in increased secretion of FGF2 protein

NCBI chr 2:120,236,328...120,290,673
Ensembl chr 2:120,236,328...120,291,221

G

Fos proto-oncogene, AP-1 transcription factor subunit

multiple interactions

[SCH772984 co-treated with bilobalide] inhibits the reaction [Oxaliplatin promotes the reaction [Morphine results in increased expression of FOS protein]]; SCH772984 inhibits the reaction [diphenylarsinic acid results in increased expression of and results in increased phosphorylation of FOS protein]; SCH772984 inhibits the reaction [Oxaliplatin promotes the reaction [Morphine results in increased expression of FOS protein]]

PMID:28087833 PMID:32319158

NCBI chr 6:105,121,170...105,124,036
Ensembl chr 6:105,121,170...105,124,036

G

G protein-coupled receptor 4

multiple interactions

SCH772984 inhibits the reaction [GPR4 protein affects the phosphorylation of MAPK1 protein]; SCH772984 inhibits the reaction [GPR4 protein affects the phosphorylation of MAPK3 protein]

NCBI chr 1:78,865,376...78,877,126
Ensembl chr 1:78,865,409...78,876,599

G

G protein-coupled receptor kinase 2

multiple interactions

SCH772984 inhibits the reaction [APP protein modified form results in increased expression of GRK2 protein]

NCBI chr 1:201,580,823...201,601,580
Ensembl chr 1:201,581,480...201,601,582

G

heme oxygenase 1

multiple interactions

SCH772984 inhibits the reaction [pachastrissamine analog results in increased expression of HMOX1 protein]

NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079

G

heat shock protein family A (Hsp70) member 1A

multiple interactions

SCH772984 inhibits the reaction [diphenylarsinic acid results in increased expression of HSPA1A protein]

NCBI chr20:3,870,765...3,873,221
Ensembl chr20:3,856,006...3,873,227

G

interleukin 6

multiple interactions

SCH772984 promotes the reaction [diphenylarsinic acid results in increased secretion of IL6 protein]

NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178

G

Jun proto-oncogene, AP-1 transcription factor subunit

multiple interactions

SCH772984 inhibits the reaction [diphenylarsinic acid results in increased expression of and results in increased phosphorylation of JUN protein]

NCBI chr 5:109,894,175...109,897,268
Ensembl chr 5:109,893,145...109,897,656

G

Kelch-like ECH-associated protein 1

multiple interactions

SCH772984 inhibits the reaction [pachastrissamine analog promotes the reaction [KEAP1 protein binds to SQSTM1 protein]]

NCBI chr 8:19,768,375...19,777,862
Ensembl chr 8:19,768,375...19,777,862

G

microtubule-associated protein 1 light chain 3 beta

multiple interactions

SCH772984 inhibits the reaction [pachastrissamine analog results in increased lipidation of MAP1LC3B protein]

NCBI chr19:49,665,795...49,673,655
Ensembl chr19:49,665,791...49,677,690

G

mitogen activated protein kinase kinase 1

increases phosphorylation

SCH772984 results in increased phosphorylation of MAP2K1 protein

NCBI chr 8:64,683,449...64,754,900
Ensembl chr 8:64,683,449...64,755,147

G

mitogen activated protein kinase kinase 2

increases phosphorylation

SCH772984 results in increased phosphorylation of MAP2K2 protein

NCBI chr 7:8,590,729...8,610,279
Ensembl chr 7:8,580,905...8,610,243

G

mitogen activated protein kinase 1

increases phosphorylation
decreases phosphorylation
multiple interactions
decreases expression
decreases activity

SCH772984 results in increased phosphorylation of MAPK1 protein
SCH772984 results in decreased phosphorylation of MAPK1 protein
SCH772984 inhibits the reaction [3,4,5-tri-O-(E)-caffeoylquinic acid analog results in increased phosphorylation of MAPK1 protein]; SCH772984 inhibits the reaction [GPR4 protein affects the phosphorylation of MAPK1 protein]; SCH772984 inhibits the reaction [Ozone results in increased phosphorylation of MAPK1 protein]; SCH772984 inhibits the reaction [pachastrissamine analog results in increased phosphorylation of MAPK1 protein]; SCH772984 inhibits the reaction [saikosaponin D results in increased phosphorylation of and results in increased activity of MAPK1 protein]
SCH772984 inhibits the reaction [diphenylarsinic acid results in increased phosphorylation of MAPK1 protein]
SCH772984 results in decreased expression of MAPK1 protein
SCH772984 results in decreased activity of MAPK1 protein

PMID:28087833 PMID:29925859 PMID:32156566 PMID:32822868 PMID:33161135 More...

NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616

G

mitogen activated protein kinase 3

decreases activity
decreases phosphorylation
decreases expression
multiple interactions
increases phosphorylation

SCH772984 results in decreased activity of MAPK3 protein
SCH772984 results in decreased phosphorylation of MAPK3 protein
SCH772984 results in decreased expression of MAPK3 protein
SCH772984 inhibits the reaction [3,4,5-tri-O-(E)-caffeoylquinic acid analog results in increased phosphorylation of MAPK3 protein]; SCH772984 inhibits the reaction [GPR4 protein affects the phosphorylation of MAPK3 protein]; SCH772984 inhibits the reaction [Ozone results in increased phosphorylation of MAPK3 protein]; SCH772984 inhibits the reaction [pachastrissamine analog results in increased phosphorylation of MAPK3 protein]; SCH772984 inhibits the reaction [saikosaponin D results in increased phosphorylation of and results in increased activity of MAPK3 protein]
SCH772984 results in increased phosphorylation of MAPK3 protein
SCH772984 inhibits the reaction [diphenylarsinic acid results in increased phosphorylation of MAPK3 protein]

PMID:28087833 PMID:29925859 PMID:32156566 PMID:32822868 PMID:33161135 More...

NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863

G

mitogen-activated protein kinase 8

decreases expression
multiple interactions

SCH772984 results in decreased expression of MAPK8 protein
SCH772984 inhibits the reaction [diphenylarsinic acid results in increased phosphorylation of MAPK8 protein]

NCBI chr16:8,638,897...8,721,960
Ensembl chr16:8,638,924...8,721,981

G

NFE2 like bZIP transcription factor 2

multiple interactions

SCH772984 inhibits the reaction [diphenylarsinic acid results in increased expression of NFE2L2 protein]

NCBI chr 3:60,594,239...60,621,712
Ensembl chr 3:60,594,242...60,621,737

G

NAD(P)H quinone dehydrogenase 1

multiple interactions

SCH772984 inhibits the reaction [pachastrissamine analog results in increased expression of NQO1 protein]

NCBI chr19:35,295,633...35,310,528
Ensembl chr19:35,295,573...35,310,557

G

RELA proto-oncogene, NF-kB subunit

multiple interactions

SCH772984 inhibits the reaction [3,4,5-tri-O-(E)-caffeoylquinic acid analog results in increased phosphorylation of RELA protein]

NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484

G

Sp1 transcription factor

multiple interactions

SCH772984 inhibits the reaction [Ethylene Chlorohydrin results in increased expression of and results in increased phosphorylation of SP1 protein]; SCH772984 inhibits the reaction [Ethylene Chlorohydrin results in increased expression of SP1 mRNA]

NCBI chr 7:133,541,302...133,571,961
Ensembl chr 7:133,541,491...133,571,961

G

Spi-1 proto-oncogene

multiple interactions

SCH772984 inhibits the reaction [saikosaponin D results in increased expression of SPI1 protein]

NCBI chr 3:77,059,744...77,093,730
Ensembl chr 3:77,073,012...77,092,393

G

sequestosome 1

multiple interactions

SCH772984 inhibits the reaction [pachastrissamine analog promotes the reaction [KEAP1 protein binds to SQSTM1 protein]]; SCH772984 inhibits the reaction [pachastrissamine analog results in increased expression of SQSTM1 protein]

NCBI chr10:34,525,517...34,536,670
Ensembl chr10:34,525,519...34,536,673

G

transforming growth factor, beta 1

multiple interactions

SCH772984 inhibits the reaction [TGFB1 protein results in increased expression of ACTA2 protein]; SCH772984 inhibits the reaction [TGFB1 protein results in increased expression of VIM protein]

NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847

G

vimentin

multiple interactions

SCH772984 inhibits the reaction [TGFB1 protein results in increased expression of VIM protein]

NCBI chr17:76,668,701...76,677,186
Ensembl chr17:76,668,647...76,677,187

Term paths to the root

Path 1
Term	Annotations
CHEBI ontology	19841
chemical entity	19839
atom	19839
nonmetal atom	19777
nitrogen atom	18962
nitrogen molecular entity	18962
organonitrogen compound	18812
carboxamide	17548
monocarboxylic acid amide	15680
pyrrolidinecarboxamide	42
(2R,4R)-N(1)-(4-chlorophenyl)-N(2)-[3-fluoro-2'-(methylsulfonyl)biphenyl-4-yl]-4-methoxypyrrolidine-1,2-dicarboxamide	0
(2S,4R)-1-acetyl-N-[(1S)-4-[(aminoiminomethyl)amino]-1-(benzothiazol-2-ylcarbonyl)butyl]-4-hydroxypyrrolidine-2-carboxamide	0
(3S)-1-cyclohexyl-5-oxo-N-phenylpyrrolidine-3-carboxamide	0
(3S)-1-cyclohexyl-N-(3,5-dichlorophenyl)-5-oxopyrrolidine-3-carboxamide	0
(3S)-N-(3-bromophenyl)-1-cyclohexyl-5-oxopyrrolidine-3-carboxamide	0
(3S)-N-(3-chloro-2-methylphenyl)-1-cyclohexyl-5-oxopyrrolidine-3-carboxamide	0
(3S)-N-(5-chloro-2-methylphenyl)-1-cyclohexyl-5-oxopyrrolidine-3-carboxamide	0
(4S)-N-hydroxy-4-(methoxyamino)-1-[(4-methoxyphenyl)sulfonyl]-D-prolinamide	0
1-(4-azido-2-nitrophenyl)amino-3-(1-oxyl-2,2,5,5-pyrrolidin-3-ylcarbonylamino)propan-2-yl diphosphate	0
1-[(2R)-2-amino-2-cyclohexylacetyl]-N-\{5-chloro-2-[2-(ethylamino)-2-oxoethoxy]benzyl\}-L-prolinamide	0
1-[2-(4-methylphenyl)ethyl]-N-[3-(4-methyl-1-piperazinyl)propyl]-5-oxo-3-pyrrolidinecarboxamide	0
1-[3,3-dimethyl-2-(2-2-methylaminopropionylamino)butyryl]-4-phenoxypyrrolidine-2-[N-(1,2,3,4-tetrahydronaphthalen-1-yl)]carboxamide	0
1-\{[1-(2-amino-3-phenylpropionyl)pyrrolidine-2-carbonyl]amino\}-2-(3-cyanophenyl)ethaneboronic acid	0
3-(2-iodacetamido)-PROXYL	0
3-[2-(2-bromoacetamido)acetamide]-PROXYL	0
3-carbamoyl-PROXYL	0
L-prolinamide	0
LSM-10075	0
LSM-10127	0
LSM-10130	0
LSM-10265	0
LSM-10374	0
LSM-10378	0
LSM-10843	0
LSM-10850	0
LSM-10968	0
LSM-10996	0
LSM-10997	0
LSM-11016	0
LSM-11045	0
LSM-11067	0
LSM-11199	0
LSM-11239	0
LSM-11262	0
LSM-11360	0
LSM-11372	0
LSM-11835	0
LSM-11836	0
LSM-11871	0
LSM-11966	0
LSM-11980	0
LSM-12023	0
LSM-12251	0
LSM-12321	0
LSM-12437	0
LSM-12589	0
LSM-12961	0
LSM-13016	0
LSM-13017	0
LSM-13040	0
LSM-13071	0
LSM-13157	0
LSM-13215	0
LSM-13242	0
LSM-13260	0
LSM-13303	0
LSM-13310	0
LSM-13469	0
LSM-13512	0
LSM-13684	0
LSM-13713	0
LSM-13728	0
LSM-13731	0
LSM-13921	0
LSM-13945	0
LSM-14013	0
LSM-14114	0
LSM-14443	0
LSM-14580	0
LSM-14583	0
LSM-14588	0
LSM-14590	0
LSM-14596	0
LSM-14599	0
LSM-14600	0
LSM-14602	0
LSM-14611	0
LSM-14617	0
LSM-14619	0
LSM-14623	0
LSM-14632	0
LSM-14635	0
LSM-14638	0
LSM-14639	0
LSM-14642	0
LSM-14643	0
LSM-14644	0
LSM-14648	0
LSM-14652	0
LSM-14661	0
LSM-14662	0
LSM-14665	0
LSM-14668	0
LSM-14670	0
LSM-14671	0
LSM-14959	0
LSM-41954	0
LSM-8600	0
LSM-8607	0
LSM-8678	0
LSM-8714	0
LSM-8744	0
LSM-8961	0
LSM-9024	0
LSM-9088	0
LSM-9202	0
LSM-9270	0
LSM-9380	0
LSM-9383	0
LSM-9422	0
LSM-9575	0
LSM-9591	0
LSM-9659	0
LSM-9681	0
LSM-9694	0
LSM-9698	0
LSM-9771	0
LSM-9838	0
LSM-9856	0
MK-8353	0
N-(3-\{[5-bromo-2-(\{3-[(pyrrolidin-1-ylcarbonyl)amino]phenyl\}amino)pyrimidin-4-yl]amino\}propyl)-2,2-dimethylmalonamide	0
N-[2-(1,3-benzodioxol-5-yl)ethyl]-1-[2-(1H-imidazol-1-yl)-6-methylpyrimidin-4-yl]-D-prolinamide	0
N-[3-(1-azepanyl)propyl]-1-[(4-methoxyphenyl)methyl]-5-oxo-3-pyrrolidinecarboxamide	0
N-[3-(1-azepanyl)propyl]-5-oxo-1-(2-phenylethyl)-3-pyrrolidinecarboxamide	0
N-[4-(morpholin-4-ylcarbonyl)benzoyl]-L-valyl-N-[(3S)-5,5,6,6,6-pentafluoro-2-methyl-4-oxohexan-3-yl]-L-prolinamide	0
N-\{[(3S,5S)-5-(1,3-thiazolidin-3-ylcarbonyl)pyrrolidin-3-yl]methyl\}-1,3-thiazole-4-carboxamide	0
N-butan-2-yl-1-[2-(4-fluorophenyl)ethyl]-5-oxo-3-pyrrolidinecarboxamide	0
SCH772984	33
Squamolone	0
acalabrutinib	3
beta-phenyl-D-phenylalanyl-N-(2,5-dichlorobenzyl)-L-prolinamide	0
celesticetin	0
clindamycin +	5
ertapenem	0
lincomycin +	6
meropenem +	2
narlaprevir	0
nirmatrelvir +	0
tetflupyrolimet	0
trofinetide	0
vaniprevir	0
Path 2
Term	Annotations
CHEBI ontology	19841
subatomic particle	19839
composite particle	19839
hadron	19839
baryon	19839
nucleon	19839
atomic nucleus	19839
atom	19839
main group element atom	19789
p-block element atom	19789
carbon group element atom	19737
carbon atom	19733
organic molecular entity	19733
heteroorganic entity	19492
organochalcogen compound	19255
organooxygen compound	19172
carbon oxoacid	18641
carboxylic acid	18638
carboacyl group	17698
univalent carboacyl group	17698
carbamoyl group	17548
carboxamide	17548
monocarboxylic acid amide	15680
pyrrolidinecarboxamide	42
(2R,4R)-N(1)-(4-chlorophenyl)-N(2)-[3-fluoro-2'-(methylsulfonyl)biphenyl-4-yl]-4-methoxypyrrolidine-1,2-dicarboxamide	0
(2S,4R)-1-acetyl-N-[(1S)-4-[(aminoiminomethyl)amino]-1-(benzothiazol-2-ylcarbonyl)butyl]-4-hydroxypyrrolidine-2-carboxamide	0
(3S)-1-cyclohexyl-5-oxo-N-phenylpyrrolidine-3-carboxamide	0
(3S)-1-cyclohexyl-N-(3,5-dichlorophenyl)-5-oxopyrrolidine-3-carboxamide	0
(3S)-N-(3-bromophenyl)-1-cyclohexyl-5-oxopyrrolidine-3-carboxamide	0
(3S)-N-(3-chloro-2-methylphenyl)-1-cyclohexyl-5-oxopyrrolidine-3-carboxamide	0
(3S)-N-(5-chloro-2-methylphenyl)-1-cyclohexyl-5-oxopyrrolidine-3-carboxamide	0
(4S)-N-hydroxy-4-(methoxyamino)-1-[(4-methoxyphenyl)sulfonyl]-D-prolinamide	0
1-(4-azido-2-nitrophenyl)amino-3-(1-oxyl-2,2,5,5-pyrrolidin-3-ylcarbonylamino)propan-2-yl diphosphate	0
1-[(2R)-2-amino-2-cyclohexylacetyl]-N-\{5-chloro-2-[2-(ethylamino)-2-oxoethoxy]benzyl\}-L-prolinamide	0
1-[2-(4-methylphenyl)ethyl]-N-[3-(4-methyl-1-piperazinyl)propyl]-5-oxo-3-pyrrolidinecarboxamide	0
1-[3,3-dimethyl-2-(2-2-methylaminopropionylamino)butyryl]-4-phenoxypyrrolidine-2-[N-(1,2,3,4-tetrahydronaphthalen-1-yl)]carboxamide	0
1-\{[1-(2-amino-3-phenylpropionyl)pyrrolidine-2-carbonyl]amino\}-2-(3-cyanophenyl)ethaneboronic acid	0
3-(2-iodacetamido)-PROXYL	0
3-[2-(2-bromoacetamido)acetamide]-PROXYL	0
3-carbamoyl-PROXYL	0
L-prolinamide	0
LSM-10075	0
LSM-10127	0
LSM-10130	0
LSM-10265	0
LSM-10374	0
LSM-10378	0
LSM-10843	0
LSM-10850	0
LSM-10968	0
LSM-10996	0
LSM-10997	0
LSM-11016	0
LSM-11045	0
LSM-11067	0
LSM-11199	0
LSM-11239	0
LSM-11262	0
LSM-11360	0
LSM-11372	0
LSM-11835	0
LSM-11836	0
LSM-11871	0
LSM-11966	0
LSM-11980	0
LSM-12023	0
LSM-12251	0
LSM-12321	0
LSM-12437	0
LSM-12589	0
LSM-12961	0
LSM-13016	0
LSM-13017	0
LSM-13040	0
LSM-13071	0
LSM-13157	0
LSM-13215	0
LSM-13242	0
LSM-13260	0
LSM-13303	0
LSM-13310	0
LSM-13469	0
LSM-13512	0
LSM-13684	0
LSM-13713	0
LSM-13728	0
LSM-13731	0
LSM-13921	0
LSM-13945	0
LSM-14013	0
LSM-14114	0
LSM-14443	0
LSM-14580	0
LSM-14583	0
LSM-14588	0
LSM-14590	0
LSM-14596	0
LSM-14599	0
LSM-14600	0
LSM-14602	0
LSM-14611	0
LSM-14617	0
LSM-14619	0
LSM-14623	0
LSM-14632	0
LSM-14635	0
LSM-14638	0
LSM-14639	0
LSM-14642	0
LSM-14643	0
LSM-14644	0
LSM-14648	0
LSM-14652	0
LSM-14661	0
LSM-14662	0
LSM-14665	0
LSM-14668	0
LSM-14670	0
LSM-14671	0
LSM-14959	0
LSM-41954	0
LSM-8600	0
LSM-8607	0
LSM-8678	0
LSM-8714	0
LSM-8744	0
LSM-8961	0
LSM-9024	0
LSM-9088	0
LSM-9202	0
LSM-9270	0
LSM-9380	0
LSM-9383	0
LSM-9422	0
LSM-9575	0
LSM-9591	0
LSM-9659	0
LSM-9681	0
LSM-9694	0
LSM-9698	0
LSM-9771	0
LSM-9838	0
LSM-9856	0
MK-8353	0
N-(3-\{[5-bromo-2-(\{3-[(pyrrolidin-1-ylcarbonyl)amino]phenyl\}amino)pyrimidin-4-yl]amino\}propyl)-2,2-dimethylmalonamide	0
N-[2-(1,3-benzodioxol-5-yl)ethyl]-1-[2-(1H-imidazol-1-yl)-6-methylpyrimidin-4-yl]-D-prolinamide	0
N-[3-(1-azepanyl)propyl]-1-[(4-methoxyphenyl)methyl]-5-oxo-3-pyrrolidinecarboxamide	0
N-[3-(1-azepanyl)propyl]-5-oxo-1-(2-phenylethyl)-3-pyrrolidinecarboxamide	0
N-[4-(morpholin-4-ylcarbonyl)benzoyl]-L-valyl-N-[(3S)-5,5,6,6,6-pentafluoro-2-methyl-4-oxohexan-3-yl]-L-prolinamide	0
N-\{[(3S,5S)-5-(1,3-thiazolidin-3-ylcarbonyl)pyrrolidin-3-yl]methyl\}-1,3-thiazole-4-carboxamide	0
N-butan-2-yl-1-[2-(4-fluorophenyl)ethyl]-5-oxo-3-pyrrolidinecarboxamide	0
SCH772984	33
Squamolone	0
acalabrutinib	3
beta-phenyl-D-phenylalanyl-N-(2,5-dichlorobenzyl)-L-prolinamide	0
celesticetin	0
clindamycin +	5
ertapenem	0
lincomycin +	6
meropenem +	2
narlaprevir	0
nirmatrelvir +	0
tetflupyrolimet	0
trofinetide	0
vaniprevir	0

paths to the root