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PATHWAY ONTOLOGY - ANNOTATIONS

The Pathway Ontology (PW), is currently being developed at the Rat Genome Database. For more information about this vocabulary, please see Petri et al. The rat genome database pathway portal. Database (Oxford). 2011 Apr 8;2011:bar010. Print 2011 or contact us (https://rgd.mcw.edu/rgdweb/contact/contactus.html).
Term:epinephrine signaling pathway via adrenergic receptor beta
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Accession:PW:0000794 term browser browse the term
Definition:Epinephrine acts as a hormone and a neurotransmitter. It promotes various actions by signaling via various adrenergic receptors, G-protein coupled receptor type. The beta receptors couple to the Galphas subunit. Beta 2 receptor may also couple to Galphai.
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epinephrine signaling pathway via adrenergic receptor beta term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adrb1 adrenoceptor beta 1 ISO RGD PMID:19110970 RGD:4140391 NCBI chr 1:265,777,103...265,780,114
Ensembl chr 1:265,766,079...265,849,237 		JBrowse link
G Adrb2 adrenoceptor beta 2 ISO RGD PMID:19110970 RGD:4140391 NCBI chr18:57,912,760...57,914,802
Ensembl chr18:57,911,348...57,914,803 		JBrowse link
G Arrb1 arrestin, beta 1 ISO RGD PMID:19229505 PMID:18268361 RGD:5135529, RGD:4140419 NCBI chr 1:163,249,654...163,321,711
Ensembl chr 1:163,250,157...163,340,859 		JBrowse link
G Arrb2 arrestin, beta 2 ISO RGD PMID:19229505 PMID:18268361 RGD:5135529, RGD:4140419 NCBI chr10:55,645,539...55,653,485
Ensembl chr10:55,645,357...55,653,487 		JBrowse link
G Gnas GNAS complex locus ISO RGD PMID:19110970 RGD:4140391 NCBI chr 3:183,489,648...183,554,570
Ensembl chr 3:183,503,243...183,554,536 		JBrowse link
G Grk2 G protein-coupled receptor kinase 2 ISO RGD PMID:19110970 PMID:19229505 RGD:4140391, RGD:5135529 NCBI chr 1:211,010,259...211,031,013
Ensembl chr 1:211,009,978...211,031,015 		JBrowse link
G Grk5 G protein-coupled receptor kinase 5 ISO RGD PMID:19110970 PMID:19229505 RGD:4140391, RGD:5135529 NCBI chr 1:270,014,314...270,208,294
Ensembl chr 1:270,014,282...270,204,928 		JBrowse link
G Snx13 sorting nexin 13 ISO RGD PMID:17173929 RGD:4140388 NCBI chr 6:57,478,139...57,589,624
Ensembl chr 6:57,434,273...57,589,624 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  pathway 6091
    signaling pathway 2635
      chemical compound signaling pathway 86
        epinephrine signaling pathway 8
          epinephrine signaling pathway via adrenergic receptor beta 8
Path 2
Term Annotations click to browse term
  pathway 6091
    signaling pathway 2635
      signaling pathway pertinent to the brain and nervous system 466
        neuron-to-neuron signaling pathways 282
          neuron-to-neuron signaling pathway via the chemical synapse 280
            epinephrine signaling pathway 8
              epinephrine signaling pathway via adrenergic receptor beta 8
paths to the root