Hoxa5 (homeo box A5) - Rat Genome Database

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Gene: Hoxa5 (homeo box A5) Rattus norvegicus
Analyze
Symbol: Hoxa5
Name: homeo box A5
RGD ID: 620609
Description: Predicted to enable DNA-binding transcription activator activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in several processes, including negative regulation of angiogenesis; regulation of gene expression; and regulation of myeloid cell differentiation. Predicted to act upstream of or within several processes, including intestinal epithelial cell maturation; mammary gland development; and respiratory system development. Predicted to be active in nucleus. Orthologous to human HOXA5 (homeobox A5); INTERACTS WITH all-trans-retinoic acid; ammonium chloride; diethylstilbestrol.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: homeobox protein Hox-1.3; homeobox protein Hox-A5; homeobox protein Hox-A5-like; hox-1.3; LOC100909641; LOC100911546; LOC103689922
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8482,632,958 - 82,636,851 (-)NCBIGRCr8
mRatBN7.2481,302,341 - 81,306,234 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl481,302,353 - 81,306,234 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx486,524,140 - 86,528,033 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0482,299,530 - 82,303,423 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0480,726,673 - 80,730,567 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0482,170,383 - 82,174,788 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl482,170,387 - 82,173,207 (-)NCBIRnor6.0rn6Rnor6.0
Rnor_5.04146,837,214 - 146,841,619 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4480,501,675 - 80,504,626 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1480,779,823 - 80,781,740 (-)NCBI
Celera476,192,532 - 76,196,931 (-)NCBICelera
Cytogenetic Map4q24NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
1,2-dimethylhydrazine  (ISO)
17beta-estradiol  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (ISO)
2-butoxyethanol  (ISO)
2-hydroxypropanoic acid  (ISO)
4,4'-sulfonyldiphenol  (ISO)
5-aza-2'-deoxycytidine  (ISO)
all-trans-retinoic acid  (EXP,ISO)
ammonium chloride  (EXP)
antirheumatic drug  (ISO)
arotinoid acid  (ISO)
arsenous acid  (ISO)
benzo[a]pyrene  (ISO)
bis(2-chloroethyl) sulfide  (ISO)
bisphenol A  (ISO)
bisphenol F  (ISO)
cadmium dichloride  (ISO)
calcitriol  (ISO)
CHIR 99021  (ISO)
chlorpyrifos  (ISO)
cisplatin  (ISO)
clobetasol  (ISO)
copper(II) chloride  (ISO)
cortisol  (ISO)
cyclosporin A  (ISO)
cytarabine  (ISO)
diarsenic trioxide  (ISO)
diethylstilbestrol  (EXP)
diuron  (EXP)
etoposide  (ISO)
flavonoids  (EXP)
folic acid  (ISO)
genistein  (ISO)
gentamycin  (EXP)
geraniol  (ISO)
lipopolysaccharide  (EXP)
mitoxantrone  (ISO)
mono(2-ethylhexyl) phthalate  (ISO)
N1'-[2-[[5-[(dimethylamino)methyl]-2-furanyl]methylthio]ethyl]-N1-methyl-2-nitroethene-1,1-diamine  (EXP)
nickel atom  (ISO)
nitrofen  (ISO)
nitrogen dioxide  (ISO)
oxaliplatin  (EXP)
ozone  (ISO)
paracetamol  (EXP,ISO)
perfluorodecanoic acid  (ISO)
perfluorononanoic acid  (ISO)
perfluorooctanoic acid  (ISO)
phosgene  (ISO)
pirinixic acid  (ISO)
quercetin  (ISO)
rac-lactic acid  (ISO)
ranitidine  (EXP)
S-(1,2-dichlorovinyl)-L-cysteine  (ISO)
SB 431542  (ISO)
silicon dioxide  (ISO)
sodium arsenite  (ISO)
stigmasterol  (ISO)
temozolomide  (ISO)
testosterone  (ISO)
thiram  (ISO)
titanium dioxide  (ISO)
topotecan  (EXP)
trichloroethene  (EXP)
trichostatin A  (ISO)
urethane  (ISO)
valproic acid  (ISO)
vinclozolin  (EXP)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
anterior/posterior pattern specification  (IBA,ISO)
bronchiole development  (ISO)
cartilage morphogenesis  (ISO)
cell migration  (ISO)
cell-cell signaling involved in mammary gland development  (ISO)
embryonic skeletal system development  (IEA,ISO)
embryonic skeletal system morphogenesis  (ISO)
epithelial tube branching involved in lung morphogenesis  (ISO)
intestinal epithelial cell maturation  (ISO)
lobar bronchus epithelium development  (ISO)
lung alveolus development  (ISO)
lung development  (ISO)
lung goblet cell differentiation  (ISO)
lung-associated mesenchyme development  (ISO)
mammary gland alveolus development  (ISO)
mammary gland epithelial cell differentiation  (ISO)
mesenchymal-epithelial cell signaling  (ISO)
morphogenesis of an epithelium  (ISO)
multicellular organism growth  (ISO)
negative regulation of angiogenesis  (IEA,ISO)
negative regulation of erythrocyte differentiation  (IEA,ISO)
pattern specification process  (ISO,TAS)
positive regulation of apoptotic process  (IEA,ISO)
positive regulation of gene expression  (IEA,ISO)
positive regulation of myeloid cell differentiation  (IEA,ISO)
positive regulation of transcription by RNA polymerase II  (IEA,ISO)
regulation of mammary gland epithelial cell proliferation  (ISO)
regulation of transcription by RNA polymerase II  (IBA)
respiratory gaseous exchange by respiratory system  (ISO)
respiratory system process  (ISO)
skeletal system development  (ISO)
thyroid gland development  (ISO)
trachea cartilage morphogenesis  (ISO)
trachea morphogenesis  (ISO)

Cellular Component
nucleus  (IBA,IEA,ISO)

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
3. Cloning and sequence analysis of homeobox transcription factor cDNAs with an inosine-containing probe. Gorski DH, etal., Biotechniques 1994 May;16(5):856-8, 860-2, 865.
4. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
5. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
6. GOA pipeline RGD automated data pipeline
7. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
8. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
9. Comprehensive gene review and curation RGD comprehensive gene curation
Additional References at PubMed
PMID:2890554   PMID:7901120   PMID:7911971   PMID:8635464   PMID:8657138   PMID:9441679   PMID:9603431   PMID:10397719   PMID:10564089   PMID:10875927   PMID:10879542   PMID:11900462  
PMID:12815622   PMID:15295088   PMID:15545268   PMID:16607641   PMID:16756717   PMID:17003488   PMID:17417799   PMID:17626057   PMID:17957028   PMID:23136161   PMID:29070584   PMID:33369800  


Genomics

Comparative Map Data
Hoxa5
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8482,632,958 - 82,636,851 (-)NCBIGRCr8
mRatBN7.2481,302,341 - 81,306,234 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl481,302,353 - 81,306,234 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx486,524,140 - 86,528,033 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0482,299,530 - 82,303,423 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0480,726,673 - 80,730,567 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0482,170,383 - 82,174,788 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl482,170,387 - 82,173,207 (-)NCBIRnor6.0rn6Rnor6.0
Rnor_5.04146,837,214 - 146,841,619 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4480,501,675 - 80,504,626 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1480,779,823 - 80,781,740 (-)NCBI
Celera476,192,532 - 76,196,931 (-)NCBICelera
Cytogenetic Map4q24NCBI
HOXA5
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38727,141,052 - 27,143,681 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl727,141,052 - 27,143,681 (-)EnsemblGRCh38hg38GRCh38
GRCh37727,180,671 - 27,183,300 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36727,147,521 - 27,149,812 (-)NCBINCBI36Build 36hg18NCBI36
Build 34726,954,235 - 26,956,527NCBI
Celera727,169,928 - 27,172,220 (-)NCBICelera
Cytogenetic Map7p15.2NCBI
HuRef727,061,238 - 27,063,851 (-)NCBIHuRef
CHM1_1727,180,379 - 27,182,993 (-)NCBICHM1_1
T2T-CHM13v2.0727,277,027 - 27,279,657 (-)NCBIT2T-CHM13v2.0
CRA_TCAGchr7v2727,231,823 - 27,234,436 (-)NCBI
Hoxa5
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39652,178,768 - 52,181,437 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl652,178,734 - 52,181,567 (-)EnsemblGRCm39 Ensembl
GRCm38652,201,754 - 52,204,587 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl652,201,754 - 52,204,587 (-)EnsemblGRCm38mm10GRCm38
MGSCv37652,151,753 - 52,154,586 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36652,131,337 - 52,134,170 (-)NCBIMGSCv36mm8
Celera652,723,406 - 52,726,239 (-)NCBICelera
Cytogenetic Map6B3NCBI
cM Map625.4NCBI
Hoxa5
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541028,834,127 - 28,838,244 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495541028,835,795 - 28,838,244 (-)NCBIChiLan1.0ChiLan1.0
HOXA5
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2631,969,814 - 31,973,097 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1780,294,841 - 80,297,564 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0727,786,040 - 27,789,339 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1727,385,175 - 27,388,990 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl727,385,175 - 27,388,990 (-)Ensemblpanpan1.1panPan2
HOXA5
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11440,315,409 - 40,319,001 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1440,315,639 - 40,317,768 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1439,746,469 - 39,750,543 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01440,253,687 - 40,258,302 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1440,254,476 - 40,256,603 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11440,368,242 - 40,372,352 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01440,053,309 - 40,057,416 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01440,411,943 - 40,416,018 (-)NCBIUU_Cfam_GSD_1.0
Hoxa5
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440511884,557,026 - 84,560,322 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364783,769,258 - 3,771,840 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364783,768,757 - 3,771,850 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
HOXA5
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1845,421,663 - 45,432,885 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11845,429,691 - 45,432,723 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21850,062,880 - 50,065,910 (+)NCBISscrofa10.2Sscrofa10.2susScr3
HOXA5
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12131,224,017 - 31,227,819 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2131,224,977 - 31,227,994 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604273,506,435 - 73,509,813 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Hoxa5
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247393,461,800 - 3,464,785 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247393,461,779 - 3,464,543 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Hoxa5
8 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:31
Count of miRNA genes:31
Interacting mature miRNAs:31
Transcripts:ENSRNOT00000008523
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1358352Srcrt3Stress Responsive Cort QTL 32.29blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)438465774146803430Rat
1549843Bw53Body weight QTL 530.0001body mass (VT:0001259)body weight gain (CMO:0000420)461697658103194791Rat
61445Strs3Sensitivity to stroke QTL 33cerebrum integrity trait (VT:0010549)post-insult time to onset of cerebrovascular lesion (CMO:0002343)44043338885433388Rat
6893678Bw108Body weight QTL 1082.60.006body mass (VT:0001259)body weight (CMO:0000012)44345797688457976Rat
10755501Bp390Blood pressure QTL 3902.5arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)426775591168368347Rat
1357342Bw40Body weight QTL 400.001body mass (VT:0001259)body weight (CMO:0000012)476647384117676292Rat
631556Bp135Blood pressure QTL 1350.017arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)478881294117676292Rat
1358363Sradr3Stress Responsive Adrenal Weight QTL 36.19adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)457486946102486946Rat
61330Eau1Experimental allergic uveoretinitis QTL 10.0003uvea integrity trait (VT:0010551)experimental autoimmune uveitis score (CMO:0001504)470362013132642728Rat
70167Bw22Body weight QTL 223.1body mass (VT:0001259)body weight (CMO:0000012)476647384117676292Rat
1549839Bw52Body weight QTL 520.0001body mass (VT:0001259)body weight gain (CMO:0000420)461697658115089733Rat
724522Bp146Blood pressure QTL 1462.20.0021arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)473630210118630210Rat
8694439Bw168Body weight QTL 1689.570.001retroperitoneal fat pad mass (VT:0010430)retroperitoneal fat pad weight to body weight ratio (CMO:0000635)44043341485433414Rat
1641919Alc22Alcohol consumption QTL 220.0005drinking behavior trait (VT:0001422)ethanol drink intake rate (CMO:0001407)481192555126192555Rat
1354660Salc1Saline consumption QTL 111.26drinking behavior trait (VT:0001422)saline drink intake rate (CMO:0001627)444463908148090542Rat
2300179Bmd50Bone mineral density QTL 505.90.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)460928534105928534Rat
1298082Stresp4Stress response QTL 4blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)450119848146803430Rat
70192BpQTLcluster5Blood pressure QTL cluster 54.183arterial blood pressure trait (VT:2000000)absolute change in mean arterial blood pressure (CMO:0000533)462933508114921294Rat
2317586Eae25Experimental allergic encephalomyelitis QTL 259.300000190734863nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis duration (CMO:0001424)47888281783007655Rat
61364Iddm2Insulin dependent diabetes mellitus QTL 2blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)478885890102684881Rat
1300139Hrtrt6Heart rate QTL 62.85heart pumping trait (VT:2000009)heart rate (CMO:0000002)439524264116179656Rat
70200Alc18Alcohol consumption QTL 189.2drinking behavior trait (VT:0001422)ethanol intake volume to total fluid intake volume ratio (CMO:0001591)456647873149491524Rat
1578657Bss12Bone structure and strength QTL 128.9femur morphology trait (VT:0000559)femoral neck cross-sectional area (CMO:0001697)460220938105220938Rat
1578658Bss13Bone structure and strength QTL 138femur strength trait (VT:0010010)femoral neck polar moment of inertia (CMO:0001670)460220938105220938Rat
2316958Gluco58Glucose level QTL 5810blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)411320076180699135Rat
6478684Anxrr30Anxiety related response QTL 300.00087defecation behavior trait (VT:0010462)defecation rate (CMO:0000998)462753847107753847Rat
2302051Pia28Pristane induced arthritis QTL 285.30.001blood autoantibody amount (VT:0003725)serum immunoglobulin G-type rheumatoid factor level relative to an arbitrary reference serum (CMO:0002112)473630210118630210Rat
8552782Vie1Viral induced encephalitis QTL 126.4brain integrity trait (VT:0010579)encephalitis incidence/prevalence measurement (CMO:0002361)43443048482490359Rat
738009Sach4Saccharine consumption QTL 44.90.000016consumption behavior trait (VT:0002069)saccharin intake volume to total fluid intake volume ratio (CMO:0001601)459948935154902892Rat
631261Tcas3Tongue tumor susceptibility QTL 36.88tongue integrity trait (VT:0010553)number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)41081417091360527Rat
2312567Glom19Glomerulus QTL 191.90.006kidney glomerulus morphology trait (VT:0005325)index of glomerular damage (CMO:0001135)445456990146803430Rat
738015Pia9Pristane induced arthritis QTL 94.50.048joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)480694870125694870Rat
6478772Anxrr49Anxiety related response QTL 490.15488defecation behavior trait (VT:0010462)defecation rate (CMO:0000998)462753847107753847Rat
631646Stl4Serum triglyceride level QTL 46.50.0001blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)473169846132642728Rat
2312569Pur19Proteinuria QTL 193.40.001urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)46588210796130297Rat
8655961Kidm43Kidney mass QTL 4318kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)436303261103194984Rat
1354612Foco1Food consumption QTL 18.87eating behavior trait (VT:0001431)food intake rate (CMO:0000427)444463908148090542Rat
634344Hcar7Hepatocarcinoma resistance QTL 77.8liver integrity trait (VT:0010547)liver tumorous lesion number (CMO:0001068)470808386115808386Rat
2303168Bp330Blood pressure QTL 3304.250.017arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)45214602146446691Rat
8552801Bw143Body weight QTL 1437.3body mass (VT:0001259)change in body weight to body weight ratio (CMO:0002216)43443048482490359Rat
738031Alc14Alcohol consumption QTL 147.60.00003consumption behavior trait (VT:0002069)ethanol drink intake rate to body weight ratio (CMO:0001616)459948935154902892Rat
8552807Vie4Viral induced encephalitis QTL 47.3brain integrity trait (VT:0010579)encephalitis incidence/prevalence measurement (CMO:0002361)46293350882490359Rat
631662Hcar2Hepatocarcinoma resistance QTL 23.10.0003liver integrity trait (VT:0010547)volume of individual liver tumorous lesion (CMO:0001078)478878504123878504Rat
1576305Emca6Estrogen-induced mammary cancer QTL 65.8mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)444463720155883716Rat
61418Pia5Pristane induced arthritis QTL 54.5joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)462277855128289560Rat
631651Bp124Blood pressure QTL 1243arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)462879517107879517Rat
8552809Vie5Viral induced encephalitis QTL 525.3brain integrity trait (VT:0010579)encephalitis incidence/prevalence measurement (CMO:0002361)43443048482490359Rat
738016Alc16Alcohol consumption QTL 163.60.00015consumption behavior trait (VT:0002069)ethanol drink intake rate to body weight ratio (CMO:0001616)459948935154902892Rat
1558651Swd3Spike wave discharge measurement QTL 34.620.000024brain electrophysiology trait (VT:0010557)brain spike-and-wave discharge frequency (CMO:0001742)45843213392991462Rat
1641833Alc21Alcohol consumption QTL 218.60.0001drinking behavior trait (VT:0001422)ethanol drink intake rate (CMO:0001407)456698790126192555Rat
2306899Bp338Blood pressure QTL 3380.071arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)481006124120102625Rat
631546Bp86Blood pressure QTL 863.2arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)45711443291360801Rat
631674Iddm14Insulin dependent diabetes mellitus QTL 14blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)464528739157573521Rat
6478743Anxrr40Anxiety related response QTL 400.83076defecation behavior trait (VT:0010462)defecation rate (CMO:0000998)462753847107753847Rat
7394826Bw126Body weight QTL 1260.002body mass (VT:0001259)body weight gain (CMO:0000420)46293326987483707Rat
12798520Anxrr55Anxiety related response QTL 554.450.01locomotor behavior trait (VT:0001392)number of rearing movements with lid-pushing in an experimental apparatus (CMO:0002715)432583980114627242Rat

Markers in Region
Hoxa5  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2481,302,662 - 81,302,813 (+)MAPPERmRatBN7.2
Rnor_6.0482,257,017 - 82,257,167NCBIRnor6.0
Rnor_6.0482,171,223 - 82,171,373NCBIRnor6.0
Rnor_5.04146,838,054 - 146,838,204UniSTSRnor5.0
Rnor_5.04146,923,848 - 146,923,998UniSTSRnor5.0
RGSC_v3.4480,502,545 - 80,502,695UniSTSRGSC3.4
Celera476,193,372 - 76,193,522UniSTS
Cytogenetic Map4q24UniSTS
stSG609349  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2481,302,015 - 81,302,234 (+)MAPPERmRatBN7.2
Rnor_6.0482,256,369 - 82,256,587NCBIRnor6.0
Rnor_6.0482,170,575 - 82,170,793NCBIRnor6.0
Rnor_5.04146,837,406 - 146,837,624UniSTSRnor5.0
Rnor_5.04146,923,200 - 146,923,418UniSTSRnor5.0
RGSC_v3.4480,501,897 - 80,502,115UniSTSRGSC3.4
Celera476,192,724 - 76,192,942UniSTS
Cytogenetic Map4q24UniSTS
MARC_6217-6218:992007117:1  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2481,302,049 - 81,302,284 (+)MAPPERmRatBN7.2
Rnor_6.0482,256,403 - 82,256,637NCBIRnor6.0
Rnor_6.0482,170,609 - 82,170,843NCBIRnor6.0
Rnor_5.04146,837,440 - 146,837,674UniSTSRnor5.0
Rnor_5.04146,923,234 - 146,923,468UniSTSRnor5.0
RGSC_v3.4480,501,931 - 80,502,165UniSTSRGSC3.4
Celera476,192,758 - 76,192,992UniSTS
Cytogenetic Map4q24UniSTS
UniSTS:57649  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2481,302,195 - 81,302,539 (+)MAPPERmRatBN7.2
Rnor_6.0482,256,549 - 82,256,893NCBIRnor6.0
Rnor_6.0482,170,755 - 82,171,099NCBIRnor6.0
Rnor_5.04146,837,586 - 146,837,930UniSTSRnor5.0
Rnor_5.04146,923,380 - 146,923,724UniSTSRnor5.0
RGSC_v3.4480,502,077 - 80,502,421UniSTSRGSC3.4
Celera476,192,904 - 76,193,248UniSTS
Cytogenetic Map4q24UniSTS
REN100511  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2481,301,937 - 81,302,212 (+)MAPPERmRatBN7.2
Rnor_6.0482,256,291 - 82,256,565NCBIRnor6.0
Rnor_6.0482,170,497 - 82,170,771NCBIRnor6.0
Rnor_5.04146,837,328 - 146,837,602UniSTSRnor5.0
Rnor_5.04146,923,122 - 146,923,396UniSTSRnor5.0
RGSC_v3.4480,501,819 - 80,502,093UniSTSRGSC3.4
Celera476,192,646 - 76,192,920UniSTS
Cytogenetic Map4q24UniSTS
REN100512  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2481,302,197 - 81,302,454 (+)MAPPERmRatBN7.2
Rnor_6.0482,256,551 - 82,256,808NCBIRnor6.0
Rnor_6.0482,170,757 - 82,171,014NCBIRnor6.0
Rnor_5.04146,837,588 - 146,837,845UniSTSRnor5.0
Rnor_5.04146,923,382 - 146,923,639UniSTSRnor5.0
RGSC_v3.4480,502,079 - 80,502,336UniSTSRGSC3.4
Celera476,192,906 - 76,193,163UniSTS
Cytogenetic Map4q24UniSTS
REN100522  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2481,304,317 - 81,304,564 (+)MAPPERmRatBN7.2
Rnor_6.0482,258,673 - 82,258,919NCBIRnor6.0
Rnor_6.0482,172,878 - 82,173,124NCBIRnor6.0
Rnor_5.04146,839,709 - 146,839,955UniSTSRnor5.0
Rnor_5.04146,925,504 - 146,925,750UniSTSRnor5.0
RGSC_v3.4480,504,201 - 80,504,447UniSTSRGSC3.4
Celera476,195,021 - 76,195,267UniSTS
Cytogenetic Map4q24UniSTS
Hoxa5  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2481,301,920 - 81,302,068 (+)MAPPERmRatBN7.2
Rnor_6.0482,256,274 - 82,256,421NCBIRnor6.0
Rnor_6.0482,170,480 - 82,170,627NCBIRnor6.0
Rnor_5.04146,837,311 - 146,837,458UniSTSRnor5.0
Rnor_5.04146,923,105 - 146,923,252UniSTSRnor5.0
RGSC_v3.4480,501,802 - 80,501,949UniSTSRGSC3.4
Celera476,192,629 - 76,192,776UniSTS
Cytogenetic Map4q24UniSTS
Hoxa5  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2481,301,925 - 81,302,107 (+)MAPPERmRatBN7.2
Rnor_6.0482,256,279 - 82,256,460NCBIRnor6.0
Rnor_6.0482,170,485 - 82,170,666NCBIRnor6.0
Rnor_5.04146,837,316 - 146,837,497UniSTSRnor5.0
Rnor_5.04146,923,110 - 146,923,291UniSTSRnor5.0
RGSC_v3.4480,501,807 - 80,501,988UniSTSRGSC3.4
Celera476,192,634 - 76,192,815UniSTS
Cytogenetic Map4q24UniSTS
Hoxa5  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2481,304,245 - 81,304,330 (+)MAPPERmRatBN7.2
Rnor_6.0482,172,806 - 82,172,890NCBIRnor6.0
Rnor_6.0482,258,601 - 82,258,685NCBIRnor6.0
Rnor_5.04146,925,432 - 146,925,516UniSTSRnor5.0
Rnor_5.04146,839,637 - 146,839,721UniSTSRnor5.0
Celera476,194,949 - 76,195,033UniSTS
Cytogenetic Map4q24UniSTS


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSRNOT00000074167   ⟹   ENSRNOP00000064639
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl481,302,353 - 81,306,234 (-)Ensembl
Rnor_6.0 Ensembl482,170,387 - 82,173,207 (-)Ensembl
RefSeq Acc Id: NM_024389   ⟹   NP_077365
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8482,632,958 - 82,636,851 (-)NCBI
mRatBN7.2481,302,341 - 81,306,234 (-)NCBI
Protein Sequences
Protein RefSeqs NP_077365 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAA67844 (Get FASTA)   NCBI Sequence Viewer  
  P52949 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_077365   ⟸   NM_024389
- UniProtKB: M0R5H2 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000064639   ⟸   ENSRNOT00000074167

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-G3V6T2-F1-model_v2 AlphaFold G3V6T2 1-270 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:620609 AgrOrtholog
BioCyc Gene G2FUF-44819 BioCyc
Ensembl Genes ENSRNOG00000047951 Ensembl
Gene3D-CATH Homeodomain-like UniProtKB/Swiss-Prot
InterPro Antp_homeobox UniProtKB/Swiss-Prot
  Homeobox-like_sf UniProtKB/Swiss-Prot
  Homeobox_antennapedia UniProtKB/Swiss-Prot
  Homeobox_Antennapedia_CS UniProtKB/Swiss-Prot
  Homeobox_CS UniProtKB/Swiss-Prot
  Homeobox_dom UniProtKB/Swiss-Prot
  Homeobox_metazoa UniProtKB/Swiss-Prot
NCBI Gene 79241 ENTREZGENE
PANTHER HOMEOBOX PROTEIN HOX UniProtKB/Swiss-Prot
  HOMEOBOX PROTEIN HOX-A5 UniProtKB/Swiss-Prot
Pfam Homeodomain UniProtKB/Swiss-Prot
PhenoGen Hoxa5 PhenoGen
PRINTS ANTENNAPEDIA UniProtKB/Swiss-Prot
  HOMEOBOX UniProtKB/Swiss-Prot
PROSITE ANTENNAPEDIA UniProtKB/Swiss-Prot
  HOMEOBOX_1 UniProtKB/Swiss-Prot
  HOMEOBOX_2 UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000047951 RatGTEx
SMART HOX UniProtKB/Swiss-Prot
Superfamily-SCOP SSF46689 UniProtKB/Swiss-Prot
UniProt HXA5_RAT UniProtKB/Swiss-Prot
  M0R5H2 ENTREZGENE
  P52949 ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2021-03-09 Hoxa5  homeo box A5  LOC103689922  homeobox protein Hox-A5  Data merged from RGD:9260675 737654 PROVISIONAL
2015-07-29 Hoxa5  homeo box A5  LOC100911546  homeobox protein Hox-A5-like  Data merged from RGD:6492497 737654 PROVISIONAL
2015-07-29 Hoxa5  homeo box A5  LOC100909641  homeobox protein Hox-A5-like  Data merged from RGD:6502805 737654 PROVISIONAL
2014-08-25 LOC103689922  homeobox protein Hox-A5      Symbol and Name status set to provisional 70820 PROVISIONAL
2012-07-05 LOC100911546  homeobox protein Hox-A5-like      Symbol and Name status set to provisional 70820 PROVISIONAL
2012-07-05 LOC100909641  homeobox protein Hox-A5-like      Symbol and Name status set to provisional 70820 PROVISIONAL
2004-09-10 Hoxa5  homeo box A5      Symbol and Name status set to approved 1299863 APPROVED
2002-08-07 Hoxa5  homeo box A5      Symbol and Name status set to provisional 70820 PROVISIONAL