Hoxa5 (homeobox A5) - Rat Genome Database

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Gene: Hoxa5 (homeobox A5) Mus musculus
Analyze
Symbol: Hoxa5
Name: homeobox A5
RGD ID: 734225
MGI Page MGI
Description: Enables DNA binding activity. Acts upstream of or within several processes, including intestinal epithelial cell maturation; mammary gland development; and respiratory system development. Located in nucleus. Is expressed in several structures, including central nervous system; embryo mesenchyme; genitourinary system; gut; and skeleton. Orthologous to human HOXA5 (homeobox A5).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: homeo box A5; homeobox protein Hox-1.3; homeobox protein Hox-A5; homeobox protein M2; Hox-1.; Hox-1.3
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39652,178,768 - 52,181,437 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl652,178,734 - 52,181,567 (-)EnsemblGRCm39 Ensembl
GRCm38652,201,754 - 52,204,587 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl652,201,754 - 52,204,587 (-)EnsemblGRCm38mm10GRCm38
MGSCv37652,151,753 - 52,154,586 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36652,131,337 - 52,134,170 (-)NCBIMGSCv36mm8
Celera652,723,406 - 52,726,239 (-)NCBICelera
Cytogenetic Map6B3NCBI
cM Map625.4NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
1,2-dimethylhydrazine  (EXP)
17beta-estradiol  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP)
2-butoxyethanol  (EXP)
2-hydroxypropanoic acid  (ISO)
4,4'-sulfonyldiphenol  (EXP,ISO)
5-aza-2'-deoxycytidine  (ISO)
all-trans-retinoic acid  (EXP,ISO)
ammonium chloride  (ISO)
antirheumatic drug  (ISO)
arotinoid acid  (ISO)
arsenous acid  (ISO)
benzo[a]pyrene  (EXP,ISO)
bis(2-chloroethyl) sulfide  (EXP)
bisphenol A  (EXP,ISO)
bisphenol F  (EXP)
cadmium dichloride  (ISO)
calcitriol  (ISO)
CHIR 99021  (ISO)
chlorpyrifos  (EXP)
cisplatin  (ISO)
clobetasol  (EXP)
copper(II) chloride  (ISO)
cortisol  (ISO)
cyclosporin A  (ISO)
cytarabine  (ISO)
diarsenic trioxide  (ISO)
diethylstilbestrol  (ISO)
diuron  (ISO)
etoposide  (ISO)
flavonoids  (ISO)
folic acid  (EXP)
genistein  (EXP)
gentamycin  (ISO)
geraniol  (ISO)
lipopolysaccharide  (ISO)
mitoxantrone  (ISO)
mono(2-ethylhexyl) phthalate  (EXP,ISO)
N1'-[2-[[5-[(dimethylamino)methyl]-2-furanyl]methylthio]ethyl]-N1-methyl-2-nitroethene-1,1-diamine  (ISO)
nickel atom  (ISO)
nitrofen  (EXP)
oxaliplatin  (ISO)
ozone  (EXP)
paracetamol  (EXP,ISO)
perfluorodecanoic acid  (EXP)
perfluorononanoic acid  (EXP)
perfluorooctanoic acid  (EXP)
phosgene  (EXP)
pirinixic acid  (EXP)
quercetin  (ISO)
rac-lactic acid  (ISO)
ranitidine  (ISO)
S-(1,2-dichlorovinyl)-L-cysteine  (ISO)
SB 431542  (ISO)
silicon dioxide  (ISO)
sodium arsenite  (ISO)
stigmasterol  (EXP)
temozolomide  (ISO)
testosterone  (ISO)
thiram  (ISO)
titanium dioxide  (EXP)
topotecan  (ISO)
trichloroethene  (ISO)
trichostatin A  (ISO)
urethane  (ISO)
valproic acid  (EXP,ISO)
vinclozolin  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
anterior/posterior pattern specification  (IBA,IGI,IMP)
bronchiole development  (IMP)
cartilage morphogenesis  (IMP)
cell migration  (IMP)
cell-cell signaling involved in mammary gland development  (IMP)
embryonic skeletal system development  (IGI)
embryonic skeletal system morphogenesis  (IMP)
epithelial tube branching involved in lung morphogenesis  (IMP)
intestinal epithelial cell maturation  (IMP)
lobar bronchus epithelium development  (IMP)
lung alveolus development  (IMP)
lung development  (IMP)
lung goblet cell differentiation  (IMP)
lung-associated mesenchyme development  (IMP)
mammary gland alveolus development  (IMP)
mammary gland epithelial cell differentiation  (IMP)
mesenchymal-epithelial cell signaling  (IMP)
morphogenesis of an epithelium  (IMP)
multicellular organism growth  (IMP)
negative regulation of angiogenesis  (ISO)
negative regulation of erythrocyte differentiation  (ISO)
pattern specification process  (IMP)
positive regulation of apoptotic process  (ISO)
positive regulation of gene expression  (ISO)
positive regulation of myeloid cell differentiation  (ISO)
positive regulation of transcription by RNA polymerase II  (IDA,ISO)
regulation of DNA-templated transcription  (IEA)
regulation of mammary gland epithelial cell proliferation  (IMP)
regulation of transcription by RNA polymerase II  (IBA)
respiratory gaseous exchange by respiratory system  (IMP)
respiratory system process  (IMP)
skeletal system development  (IMP)
thyroid gland development  (IMP)
trachea cartilage morphogenesis  (IMP)
trachea morphogenesis  (IMP)

Cellular Component
nucleus  (IBA,IDA,ISO)

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
abnormal alveolar macrophage morphology  (IAGP)
abnormal axial skeleton morphology  (IAGP)
abnormal branching involved in lung morphogenesis  (IAGP)
abnormal bronchiole epithelium morphology  (IAGP)
abnormal bronchiole morphology  (IAGP)
abnormal bronchus epithelium morphology  (IAGP)
abnormal cell migration  (IAGP)
abnormal cervical vertebrae morphology  (IAGP)
abnormal cricoid cartilage morphology  (IAGP)
abnormal digestive secretion  (IAGP)
abnormal estrous cycle  (IAGP)
abnormal intervertebral disk morphology  (IAGP)
abnormal larynx morphology  (IAGP)
abnormal lung development  (IAGP)
abnormal lung saccule morphology  (IAGP)
abnormal lung weight  (IAGP)
abnormal pulmonary acinus morphology  (IAGP)
abnormal pulmonary alveolar parenchyma morphology  (IAGP)
abnormal pulmonary alveolar sac morphology  (IAGP)
abnormal pulmonary alveolus morphology  (IAGP)
abnormal pulmonary elastic fiber morphology  (IAGP)
abnormal pulmonary interalveolar septum morphology  (IAGP)
abnormal respiratory mucosa goblet cell morphology  (IAGP)
abnormal rib development  (IAGP)
abnormal rib joint morphology  (IAGP)
abnormal rib morphology  (IAGP)
abnormal skeleton morphology  (IAGP)
abnormal surfactant secretion  (IAGP)
abnormal thyroid gland development  (IAGP)
abnormal trachea morphology  (IAGP)
abnormal tracheal cartilage morphology  (IAGP)
abnormal vertebrae morphology  (IAGP)
abnormal xiphoid process morphology  (IAGP)
absent sternal manubrium  (IAGP)
asymmetric sternocostal joints  (IAGP)
atelectasis  (IAGP)
cervical vertebral fusion  (IAGP)
cervical vertebral transformation  (IAGP)
cricoid and tracheal cartilage fusion  (IAGP)
cyanosis  (IAGP)
decreased rib number  (IAGP)
decreased surfactant secretion  (IAGP)
decreased tracheal cartilage ring number  (IAGP)
delayed ear emergence  (IAGP)
delayed eyelid opening  (IAGP)
early sexual maturation  (IAGP)
emphysema  (IAGP)
impaired branching involved in bronchus morphogenesis  (IAGP)
impaired branching involved in respiratory bronchiole morphogenesis  (IAGP)
impaired lung alveolus development  (IAGP)
increased circulating estradiol level  (IAGP)
increased circulating thyroid-stimulating hormone level  (IAGP)
increased respiratory mucosa goblet cell number  (IAGP)
increased rib number  (IAGP)
increased sternebra number  (IAGP)
increased type II pneumocyte number  (IAGP)
lumbar vertebral transformation  (IAGP)
lung cyst  (IAGP)
lung inflammation  (IAGP)
meteorism  (IAGP)
neonatal lethality, incomplete penetrance  (IAGP)
no abnormal phenotype detected  (IAGP)
ovary cyst  (IAGP)
overexpanded pulmonary alveolus  (IAGP)
perinatal lethality, incomplete penetrance  (IAGP)
postnatal growth retardation  (IAGP)
postnatal lethality, incomplete penetrance  (IAGP)
prolonged diestrus  (IAGP)
prolonged estrous cycle  (IAGP)
prolonged metestrus  (IAGP)
respiratory distress  (IAGP)
rib fusion  (IAGP)
short estrus  (IAGP)
short sternum  (IAGP)
small thoracic cage  (IAGP)
sternebra fusion  (IAGP)
thick pulmonary interalveolar septum  (IAGP)
thoracic vertebral transformation  (IAGP)
trachea occlusion  (IAGP)
trachea stenosis  (IAGP)
vertebral transformation  (IAGP)
References

References - curated
# Reference Title Reference Citation
1. Hox-1.6: a mouse homeo-box-containing gene member of the Hox-1 complex. Baron A, etal., EMBO J 1987 Oct;6(10):2977-86.
2. MGDs mouse GO annotations MGD data from the GO Consortium
3. MGD IEA MGD IEA
4. Mouse MP Annotation Import Pipeline RGD automated import pipeline
5. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
6. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:1346779   PMID:1348361   PMID:1358459   PMID:1676977   PMID:1683707   PMID:1717831   PMID:1976088   PMID:2416462   PMID:2563568   PMID:2565857   PMID:2575552   PMID:2890554  
PMID:2891502   PMID:2901335   PMID:3019676   PMID:7546287   PMID:7628698   PMID:7680626   PMID:7901120   PMID:7909996   PMID:7910023   PMID:7911971   PMID:7918106   PMID:8095481  
PMID:8099712   PMID:8395283   PMID:8486351   PMID:8625838   PMID:8635464   PMID:8833244   PMID:8887324   PMID:9043087   PMID:9367423   PMID:9415485   PMID:9441679   PMID:9603431  
PMID:10030592   PMID:10075847   PMID:10349636   PMID:10564089   PMID:10579975   PMID:10633854   PMID:11042159   PMID:11044609   PMID:11053021   PMID:11076861   PMID:11217851   PMID:11869294  
PMID:11900462   PMID:12163409   PMID:12163410   PMID:12370779   PMID:12466851   PMID:12477932   PMID:12527197   PMID:12815622   PMID:12953790   PMID:15042701   PMID:15087118   PMID:15158076  
PMID:15295088   PMID:15352125   PMID:15489334   PMID:15618518   PMID:15680324   PMID:15741318   PMID:15922675   PMID:16024804   PMID:16109395   PMID:16139370   PMID:16141072   PMID:16141073  
PMID:16602821   PMID:16607641   PMID:16618927   PMID:16971476   PMID:17003488   PMID:17107999   PMID:17417799   PMID:17535249   PMID:17572674   PMID:17626057   PMID:17726103   PMID:18287559  
PMID:18324732   PMID:18553509   PMID:18662545   PMID:19204410   PMID:19262140   PMID:19458547   PMID:19853565   PMID:19922872   PMID:20042682   PMID:20059953   PMID:20211142   PMID:20485555  
PMID:20599664   PMID:20711475   PMID:20826310   PMID:21049546   PMID:21267068   PMID:21309069   PMID:21529712   PMID:21677750   PMID:21873635   PMID:22219351   PMID:22315454   PMID:22675207  
PMID:22701719   PMID:22711520   PMID:22811268   PMID:22872086   PMID:23103965   PMID:23213461   PMID:23307742   PMID:23359544   PMID:23585229   PMID:23843306   PMID:24218595   PMID:24307483  
PMID:24496616   PMID:24525295   PMID:24705708   PMID:25079229   PMID:25099890   PMID:25100655   PMID:25381007   PMID:25516969   PMID:25590986   PMID:25821967   PMID:26235626   PMID:26283362  
PMID:26329601   PMID:26395370   PMID:26678341   PMID:26820751   PMID:26904955   PMID:26930384   PMID:27568519   PMID:27650319   PMID:27974206   PMID:28009287   PMID:28041967   PMID:28188179  
PMID:28337978   PMID:28363633   PMID:28576978   PMID:28609438   PMID:28811488   PMID:28827394   PMID:29031500   PMID:29074702   PMID:29187810   PMID:29379870   PMID:29439250   PMID:29632085  
PMID:29651293   PMID:30169530   PMID:30242124   PMID:30311912   PMID:30348760   PMID:30604848   PMID:31427287   PMID:31441588   PMID:31747609   PMID:32325033   PMID:32479258   PMID:32553152  
PMID:33202249   PMID:33257809   PMID:33298461   PMID:33732701   PMID:34098726   PMID:34108202   PMID:34117711   PMID:34126188   PMID:34994686   PMID:35315772   PMID:35557949   PMID:35623098  
PMID:36166646   PMID:36167790   PMID:36563692   PMID:36577717   PMID:37167859   PMID:37626900   PMID:38521405  


Genomics

Comparative Map Data
Hoxa5
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39652,178,768 - 52,181,437 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl652,178,734 - 52,181,567 (-)EnsemblGRCm39 Ensembl
GRCm38652,201,754 - 52,204,587 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl652,201,754 - 52,204,587 (-)EnsemblGRCm38mm10GRCm38
MGSCv37652,151,753 - 52,154,586 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36652,131,337 - 52,134,170 (-)NCBIMGSCv36mm8
Celera652,723,406 - 52,726,239 (-)NCBICelera
Cytogenetic Map6B3NCBI
cM Map625.4NCBI
HOXA5
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38727,141,052 - 27,143,681 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl727,141,052 - 27,143,681 (-)EnsemblGRCh38hg38GRCh38
GRCh37727,180,671 - 27,183,300 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36727,147,521 - 27,149,812 (-)NCBINCBI36Build 36hg18NCBI36
Build 34726,954,235 - 26,956,527NCBI
Celera727,169,928 - 27,172,220 (-)NCBICelera
Cytogenetic Map7p15.2NCBI
HuRef727,061,238 - 27,063,851 (-)NCBIHuRef
CHM1_1727,180,379 - 27,182,993 (-)NCBICHM1_1
T2T-CHM13v2.0727,277,027 - 27,279,657 (-)NCBIT2T-CHM13v2.0
CRA_TCAGchr7v2727,231,823 - 27,234,436 (-)NCBI
Hoxa5
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8482,632,958 - 82,636,851 (-)NCBIGRCr8
mRatBN7.2481,302,341 - 81,306,234 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl481,302,353 - 81,306,234 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx486,524,140 - 86,528,033 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0482,299,530 - 82,303,423 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0480,726,673 - 80,730,567 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0482,170,383 - 82,174,788 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl482,170,387 - 82,173,207 (-)NCBIRnor6.0rn6Rnor6.0
Rnor_5.04146,837,214 - 146,841,619 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4480,501,675 - 80,504,626 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1480,779,823 - 80,781,740 (-)NCBI
Celera476,192,532 - 76,196,931 (-)NCBICelera
Cytogenetic Map4q24NCBI
Hoxa5
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541028,834,127 - 28,838,244 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495541028,835,795 - 28,838,244 (-)NCBIChiLan1.0ChiLan1.0
HOXA5
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2631,969,814 - 31,973,097 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1780,294,841 - 80,297,564 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0727,786,040 - 27,789,339 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1727,385,175 - 27,388,990 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl727,385,175 - 27,388,990 (-)Ensemblpanpan1.1panPan2
HOXA5
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11440,315,409 - 40,319,001 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1440,315,639 - 40,317,768 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1439,746,469 - 39,750,543 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01440,253,687 - 40,258,302 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1440,254,476 - 40,256,603 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11440,368,242 - 40,372,352 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01440,053,309 - 40,057,416 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01440,411,943 - 40,416,018 (-)NCBIUU_Cfam_GSD_1.0
Hoxa5
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440511884,557,026 - 84,560,322 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364783,769,258 - 3,771,840 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364783,768,757 - 3,771,850 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
HOXA5
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1845,421,663 - 45,432,885 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11845,429,691 - 45,432,723 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21850,062,880 - 50,065,910 (+)NCBISscrofa10.2Sscrofa10.2susScr3
HOXA5
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12131,224,017 - 31,227,819 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2131,224,977 - 31,227,994 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604273,506,435 - 73,509,813 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Hoxa5
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247393,461,800 - 3,464,785 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247393,461,779 - 3,464,543 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Hoxa5
54 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:288
Count of miRNA genes:211
Interacting mature miRNAs:242
Transcripts:ENSMUST00000048794
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
4142271Egq8_mearly growth QTL 8 (mouse)Not determined450382396633110Mouse
1301266Lmr4_mleishmaniasis resistance 4 (mouse)Not determined64209335876093500Mouse
12910785Pwgrq16_mpost-weaning growth rate QTL 16 (mouse)64380374777788506Mouse
11252142Mom12_mModifier of Min 12 (mouse)63387226167872400Mouse
14696807Rbcn2_mrod bipolar cell number 2 (mouse)65118698056186985Mouse
4140983Srilp_msleep response to influenza, light phase (mouse)Not determined4870349075424693Mouse
12910798Pwgrq5_mpre-weaning growth rate QTL 5 (mouse)64380374777788506Mouse
1300767Aliq4_macute lung injury QTL 4 (mouse)Not determined63627333270273435Mouse
4142259Tabw2_mtally ho associated body weight 2 (mouse)Not determined46912919136400690Mouse
25314319Histh6_mhistamine hypersensitivity 6 (mouse)648696934125336963Mouse
4142126W3q3_mweight 3 weeks QTL 3 (mouse)Not determined450382396633110Mouse
25314320Histh5_mhistamine hypersensitivity 5 (mouse)648696934148351498Mouse
12910807Pwbwq11_mpost-weaning body weight QTL 11 (mouse)64380374777788506Mouse
14746995Manh60_mmandible shape 60 (mouse)63720266271202662Mouse
1301254Skts11_mskin tumor susceptibility 11 (mouse)Not determined65115613485156284Mouse
1357442Dbts1_mdiabetes 1 (mouse)Not determined61823414773364675Mouse
12910802Pwbwq12_mpost-weaning body weight QTL 12 (mouse)64380374777788506Mouse
4141094Hrtr1_mheart rate 1 (mouse)Not determined3674146370741463Mouse
1300618Pgia19_mproteoglycan induced arthritis 19 (mouse)Not determined64529099387403016Mouse
4141988Obrq3_mobesity resistance QTL 3 (mouse)Not determined2829099362291115Mouse
12910809Pwbwq10_mpost-weaning body weight QTL 10 (mouse)64380374777788506Mouse
12910820Ogrq3_moverall growth rate QTL 3 (mouse)64380374777788506Mouse
26884414Bzwq12_mbi-zygomatic width QTL 12, 16 week (mouse)63400000139076998Mouse
4142361W10q11_mweight 10 weeks QTL 11 (mouse)Not determined450382396633110Mouse
4142232W6q4_mweight 6 weeks QTL 4 (mouse)Not determined450382396633110Mouse
12904940Edlmmq5_mextensor digitorum longus muscle mass QTL 5 (mouse)61961634653616346Mouse
10412213Sxbq2_mSGC/Knj cross B6 QTL 2 (mouse)Not determined61991268571299759Mouse
12904943Tammq4_mtibialis anterior muscle mass QTL 4 (mouse)61961634653616346Mouse
4141454Obrq4_mobesity resistance QTL 4 (mouse)Not determined3170349965703611Mouse
12904952Gmmq4_mgastrocnemius muscle mass QTL 4 (mouse)61961634653616346Mouse
13208564Bmiq7_mbody mass index QTL 7 (mouse)62499999979976983Mouse
26884441Sklq3_mskull length QTL 3, 5 week (mouse)6760000080576983Mouse
1300959Lxw2_mlupus BXSB x NZW 2 (mouse)Not determined63387226167872400Mouse
10412107Desp4_mdespair 4 (mouse)Not determined62004983054049830Mouse
1301962Eila2_methanol induced locomotor activity 2 (mouse)Not determined648703490125333748Mouse
1301326Trbv4c2_mT cell receptor beta variable 4 (mouse)Not determined64086823071356155Mouse
1558984Cplaq9_mcircadian period of locomotor activity 9 (mouse)Not determined63864656092584431Mouse
1300556Cia6_mcollagen induced arthritis QTL 6 (mouse)Not determined6446488487403016Mouse
10412157Fl1n_mfatty liver 1 in NSY (mouse)Not determined645290993128811995Mouse
25440480Moaq2_mmodifier of alien QTL 2 (mouse)63050001117476961Mouse
1357683Igf1sl1_mIGF-1 serum levels 1 (mouse)Not determined652138693116132228Mouse
4141782Mrdq5_mmodifier of retinal degeneration QTL 5 (mouse)Not determined3282758578215957Mouse
12880424V25Dq4_mvitamin D inactive form serum level QTL 4 (mouse)64157698575576985Mouse
12880425V25Dq5_mvitamin D inactive form serum level QTL 5 (mouse)63267698066676980Mouse
11040600Lmr4c_mleishmaniasis resistance 4c (mouse)64209335876093500Mouse
11040601Lmr4a_mleishmaniasis resistance 4a (mouse)64209335876093500Mouse
14700690Ccs6_mcolon cancer susceptibility 6 (mouse)62377693457776934Mouse
10043885Cia6c_mcollagen induced arthritis QTL 6c (mouse)Not determined64444280571096451Mouse
11533915Mts4_mmammary tumor susceptibility 4 (mouse)64209335876093500Mouse
1357539Bsbob3_mBSB obesity 3 (mouse)Not determined63644845670448576Mouse
27226726Tibmd7_mtibia midshaft diameter 7, 16 week (mouse)61769999953476985Mouse

Markers in Region
Y00208  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38652,202,238 - 52,202,427UniSTSGRCm38
MGSCv37652,152,237 - 52,152,426UniSTSGRCm37
Celera652,723,890 - 52,724,079UniSTS
Cytogenetic Map6B3UniSTS
cM Map626.3UniSTS
cM Map626.3UniSTS
Whitehead_YAC6 UniSTS
REN100512  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38652,202,149 - 52,202,397UniSTSGRCm38
MGSCv37652,152,148 - 52,152,396UniSTSGRCm37
Celera652,723,801 - 52,724,049UniSTS
Cytogenetic Map6B3UniSTS
cM Map626.3UniSTS
cM Map626.3UniSTS
REN100511  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38652,201,889 - 52,202,163UniSTSGRCm38
MGSCv37652,151,888 - 52,152,162UniSTSGRCm37
Celera652,723,541 - 52,723,815UniSTS
Cytogenetic Map6B3UniSTS
cM Map626.3UniSTS
cM Map626.3UniSTS
REN100523  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38652,204,358 - 52,204,587UniSTSGRCm38
MGSCv37652,154,357 - 52,154,586UniSTSGRCm37
Celera652,726,010 - 52,726,239UniSTS
Cytogenetic Map6B3UniSTS
cM Map626.3UniSTS
cM Map626.3UniSTS
REN100522  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38652,204,258 - 52,204,504UniSTSGRCm38
MGSCv37652,154,257 - 52,154,503UniSTSGRCm37
Celera652,725,910 - 52,726,156UniSTS
Cytogenetic Map6B3UniSTS
cM Map626.3UniSTS
cM Map626.3UniSTS
REN100524  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38652,204,565 - 52,204,805UniSTSGRCm38
MGSCv37652,154,564 - 52,154,804UniSTSGRCm37
Celera652,726,217 - 52,726,457UniSTS
Cytogenetic Map6B3UniSTS
cM Map626.3UniSTS
cM Map626.3UniSTS
Hoxa5  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map6B3UniSTS
cM Map626.3UniSTS
Hoxa5  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38652,202,602 - 52,202,752UniSTSGRCm38
MGSCv37652,152,601 - 52,152,751UniSTSGRCm37
Celera652,724,254 - 52,724,404UniSTS
Cytogenetic Map6B3UniSTS
cM Map626.3UniSTS
stSG609349  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38652,201,967 - 52,202,185UniSTSGRCm38
MGSCv37652,151,966 - 52,152,184UniSTSGRCm37
Celera652,723,619 - 52,723,837UniSTS
Cytogenetic Map6B3UniSTS
cM Map626.3UniSTS
cM Map626.3UniSTS
MARC_6217-6218:992007117:1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38652,202,001 - 52,202,235UniSTSGRCm38
MGSCv37652,152,000 - 52,152,234UniSTSGRCm37
Celera652,723,653 - 52,723,887UniSTS
Cytogenetic Map6B3UniSTS
cM Map626.3UniSTS
cM Map626.3UniSTS
Hoxa5  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map6B3UniSTS
cM Map626.3UniSTS
Hoxa5  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38652,201,872 - 52,202,019UniSTSGRCm38
MGSCv37652,151,871 - 52,152,018UniSTSGRCm37
Celera652,723,524 - 52,723,671UniSTS
Cytogenetic Map6B3UniSTS
cM Map626.3UniSTS
Hoxa5  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38652,201,877 - 52,202,058UniSTSGRCm38
MGSCv37652,151,876 - 52,152,057UniSTSGRCm37
Celera652,723,529 - 52,723,710UniSTS
Cytogenetic Map6B3UniSTS
cM Map626.3UniSTS
UniSTS:57649  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38652,202,147 - 52,202,482UniSTSGRCm38
MGSCv37652,152,146 - 52,152,481UniSTSGRCm37
Celera652,723,799 - 52,724,134UniSTS
Cytogenetic Map6B3UniSTS
cM Map626.3UniSTS
cM Map626.3UniSTS
Hoxa5  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map6B3UniSTS
cM Map626.3UniSTS


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSMUST00000048794   ⟹   ENSMUSP00000039012
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl652,178,734 - 52,181,567 (-)Ensembl
GRCm38.p6 Ensembl652,201,754 - 52,204,587 (-)Ensembl
RefSeq Acc Id: NM_010453   ⟹   NP_034583
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39652,178,768 - 52,181,437 (-)NCBI
GRCm38652,201,754 - 52,204,587 (-)ENTREZGENE
MGSCv37652,151,753 - 52,154,586 (-)RGD
Celera652,723,406 - 52,726,239 (-)RGD
cM Map6 ENTREZGENE
Sequence:
RefSeq Acc Id: NP_034583   ⟸   NM_010453
- UniProtKB: Q91VQ5 (UniProtKB/Swiss-Prot),   P09021 (UniProtKB/Swiss-Prot),   Q3UNA0 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSMUSP00000039012   ⟸   ENSMUST00000048794
Protein Domains
Homeobox

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P09021-F1-model_v2 AlphaFold P09021 1-270 view protein structure

Promoters
RGD ID:6839460
Promoter ID:MM_KWN:46011
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day1,   3T3L1_Day2,   3T3L1_Day3,   3T3L1_Day4,   Kidney,   Liver,   Lung,   MEF_B4,   MEF_B6
Transcripts:NM_010453
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36652,154,376 - 52,155,132 (-)MPROMDB

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:96177 AgrOrtholog
Ensembl Genes ENSMUSG00000038253 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSMUST00000048794 ENTREZGENE
  ENSMUST00000048794.7 UniProtKB/Swiss-Prot
Gene3D-CATH Homeodomain-like UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro Antp_homeobox UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Homeobox-like_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Homeobox_antennapedia UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Homeobox_Antennapedia_CS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Homeobox_CS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Homeobox_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Homeobox_metazoa UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:15402 UniProtKB/Swiss-Prot
MGD MGI:96177 ENTREZGENE
NCBI Gene 15402 ENTREZGENE
PANTHER HOMEOBOX PROTEIN HOX UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  HOMEOBOX PROTEIN HOX-A5 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam Homeodomain UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Hoxa5 PhenoGen
PRINTS ANTENNAPEDIA UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  HOMEOBOX UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE ANTENNAPEDIA UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  HOMEOBOX_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  HOMEOBOX_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART HOX UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF46689 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt HXA5_MOUSE UniProtKB/Swiss-Prot, ENTREZGENE
  Q3UNA0 ENTREZGENE, UniProtKB/TrEMBL
  Q91VQ5 ENTREZGENE
UniProt Secondary Q91VQ5 UniProtKB/Swiss-Prot