Cwc22 (CWC22 spliceosome associated protein) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Advanced Search (OLGA)
Gene: Cwc22 (CWC22 spliceosome associated protein) Rattus norvegicus
Analyze
Symbol: Cwc22
Name: CWC22 spliceosome associated protein
RGD ID: 1565385
Description: Predicted to enable RNA binding activity. Predicted to be involved in mRNA splicing, via spliceosome. Predicted to be located in cytosol and nuclear speck. Predicted to be part of U2-type catalytic step 1 spliceosome; U2-type catalytic step 2 spliceosome; and U2-type precatalytic spliceosome. Orthologous to human CWC22 (CWC22 spliceosome associated protein homolog); INTERACTS WITH 3-chloropropane-1,2-diol; atrazine; bisphenol A.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: CWC22 homolog, spliceosome-associated protein; CWC22 spliceosome associated protein homolog; CWC22 spliceosome-associated protein; CWC22 spliceosome-associated protein homolog; CWC22 spliceosome-associated protein homolog (S. cerevisiae); LOC362153; pre-mRNA-splicing factor CWC22 homolog; RGD1565385; similar to mKIAA1604 protein
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Related Pseudogenes: Cwc22-ps1  
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8383,222,400 - 83,271,427 (-)NCBIGRCr8
mRatBN7.2362,815,230 - 62,864,269 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl362,802,045 - 62,864,228 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx366,163,694 - 66,212,505 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0374,747,356 - 74,796,169 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0372,514,819 - 72,563,630 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0364,731,145 - 64,780,127 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl364,731,381 - 64,766,472 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0371,298,090 - 71,346,831 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4360,560,959 - 60,600,491 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera362,293,622 - 62,342,514 (-)NCBICelera
Cytogenetic Map3q24NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function
protein binding  (ISO)
RNA binding  (IBA,ISO)

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. GOA pipeline RGD automated data pipeline
3. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
4. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:11991638   PMID:22961380   PMID:28076346   PMID:29301961   PMID:29360106  


Genomics

Comparative Map Data
Cwc22
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8383,222,400 - 83,271,427 (-)NCBIGRCr8
mRatBN7.2362,815,230 - 62,864,269 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl362,802,045 - 62,864,228 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx366,163,694 - 66,212,505 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0374,747,356 - 74,796,169 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0372,514,819 - 72,563,630 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0364,731,145 - 64,780,127 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl364,731,381 - 64,766,472 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0371,298,090 - 71,346,831 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4360,560,959 - 60,600,491 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera362,293,622 - 62,342,514 (-)NCBICelera
Cytogenetic Map3q24NCBI
CWC22
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382179,944,876 - 180,007,297 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2179,944,876 - 180,007,297 (-)EnsemblGRCh38hg38GRCh38
GRCh372180,809,603 - 180,872,024 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362180,517,849 - 180,580,025 (-)NCBINCBI36Build 36hg18NCBI36
Celera2174,403,852 - 174,466,024 (-)NCBICelera
Cytogenetic Map2q31.3NCBI
HuRef2172,661,628 - 172,723,794 (-)NCBIHuRef
CHM1_12180,815,566 - 180,877,744 (-)NCBICHM1_1
T2T-CHM13v2.02180,428,148 - 180,490,575 (-)NCBIT2T-CHM13v2.0
Cwc22
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39277,706,312 - 77,776,705 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl277,711,503 - 77,776,719 (-)EnsemblGRCm39 Ensembl
GRCm38277,881,159 - 77,946,356 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl277,881,159 - 77,946,375 (-)EnsemblGRCm38mm10GRCm38
MGSCv37277,733,710 - 77,784,240 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36277,696,492 - 77,747,022 (-)NCBIMGSCv36mm8
Celera279,551,577 - 79,602,185 (-)NCBICelera
Cytogenetic Map2C3NCBI
cM Map246.45NCBI
Cwc22
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540317,083,414 - 17,125,982 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495540317,070,588 - 17,125,918 (+)NCBIChiLan1.0ChiLan1.0
CWC22
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21382,591,580 - 82,653,836 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12B82,606,555 - 82,668,811 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02B67,198,535 - 67,261,588 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12B184,901,707 - 184,963,884 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2B184,901,960 - 184,945,273 (-)Ensemblpanpan1.1panPan2
CWC22
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13623,355,501 - 23,415,059 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3623,168,979 - 23,397,045 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3623,376,571 - 23,436,155 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.03623,516,478 - 23,576,097 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3623,517,114 - 23,575,942 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13623,610,743 - 23,670,030 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03623,573,499 - 23,633,169 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03623,696,818 - 23,756,425 (-)NCBIUU_Cfam_GSD_1.0
Cwc22
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405303140,350,710 - 140,406,968 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365098,903,833 - 8,960,882 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365098,904,613 - 8,960,852 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CWC22
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1585,542,258 - 85,605,614 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11585,541,158 - 85,605,837 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21595,114,817 - 95,179,163 (-)NCBISscrofa10.2Sscrofa10.2susScr3
CWC22
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11065,464,537 - 65,527,530 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1065,463,390 - 65,527,520 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666040134,022,070 - 134,086,162 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Cwc22
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248441,785,775 - 1,846,608 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248441,787,668 - 1,846,167 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Cwc22
251 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:147
Count of miRNA genes:103
Interacting mature miRNAs:115
Transcripts:ENSRNOT00000037684
Prediction methods:Microtar, Miranda, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1582238Bw68Body weight QTL 683.20.0064body mass (VT:0001259)body weight (CMO:0000012)353184593115665732Rat
1582239Epfw1Epididymal fat weight QTL 14.50.0006epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)353184593115665732Rat
2298542Neuinf11Neuroinflammation QTL 113.9nervous system integrity trait (VT:0010566)spinal cord complement component 1, q subcomponent, B chain mRNA level (CMO:0002126)31500542276927699Rat
1358362Srcrt2Stress Responsive Cort QTL 22.78blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)338192233133483320Rat
737818Hcar12Hepatocarcinoma resistance QTL 122.6liver integrity trait (VT:0010547)volume of individual liver tumorous lesion (CMO:0001078)329463235118376539Rat
1582218Bw74Body weight QTL 743.90.0021body mass (VT:0001259)body weight (CMO:0000012)353184593115665732Rat
1581568Rf53Renal function QTL 53urine total protein amount (VT:0000032)urine protein excretion rate to body weight ratio (CMO:0001099)356395968161299569Rat
9590286Uminl1Urine mineral level QTL 13.50.001urine mineral amount (VT:0015086)urine electrolyte level (CMO:0000593)32824968773249687Rat
1300111Rf12Renal function QTL 123.78renal blood flow trait (VT:2000006)absolute change in renal blood flow rate (CMO:0001168)361017749121056321Rat
724523Tsu1Thymus enlargement suppressive QTL 13.84thymus mass (VT:0004954)thymus weight to body weight ratio (CMO:0000612)350437504115638231Rat
8662816Vetf4Vascular elastic tissue fragility QTL 44renal artery integrity trait (VT:0010642)number of ruptures of the internal elastic lamina of the renal arteries (CMO:0002563)359242096157323038Rat
1581503Cm58Cardiac mass QTL 582.70.05heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)343827364121056321Rat
2292613Ept16Estrogen-induced pituitary tumorigenesis QTL 168.3pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)347233430110362260Rat
731180Bp152Blood pressure QTL 1520.03arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)35378111291609953Rat
631200Cm25Cardiac mass QTL 254.80.0001heart left ventricle mass (VT:0007031)heart left ventricle wet weight (CMO:0000071)36113434889115068Rat
61356Bp37Blood pressure QTL 373blood pressure trait (VT:0000183)systolic blood pressure (CMO:0000004)33068464275684642Rat
1358905Hrtrt17Heart rate QTL 175.90.000014heart pumping trait (VT:2000009)heart rate (CMO:0000002)31086191289878372Rat
8694196Abfw2Abdominal fat weight QTL 216.580.001visceral adipose mass (VT:0010063)abdominal fat pad weight to body weight ratio (CMO:0000095)32824968773249687Rat
2301971Cm71Cardiac mass QTL 714.63heart left ventricle mass (VT:0007031)heart left ventricle weight (CMO:0000776)341874578155617519Rat
1358885Bp251Blood pressure QTL 2513.8arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)314489145121056321Rat
2301970Bw81Body weight QTL 815.19body mass (VT:0001259)body weight (CMO:0000012)341874578155617519Rat
1582249Bw77Body weight QTL 773.20.0025epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)35318459364655484Rat
2290452Scl56Serum cholesterol level QTL 562.26blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)3191609953Rat
12879868Am6Aortic mass QTL 60.001aorta mass (VT:0002845)aorta weight to aorta length to body weight ratio (CMO:0002722)33142640370668733Rat
11565451Bw177Body weight QTL 1770.002body mass (VT:0001259)body weight (CMO:0000012)33142640370668733Rat
1358888Bp264Blood pressure QTL 2644.43arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)314489145121056321Rat
11565452Kidm57Kidney mass QTL 570.001kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)33142640370668733Rat
12879866Cm94Cardiac mass QTL 940.001heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)33142640370668733Rat
12879867Cm95Cardiac mass QTL 950.047heart right ventricle mass (VT:0007033)heart right ventricle weight to body weight ratio (CMO:0000914)33142640370668733Rat
1300178Hrtrt4Heart rate QTL 43.74heart pumping trait (VT:2000009)heart rate (CMO:0000002)34382736490905114Rat
61377Edpm3Estrogen-dependent pituitary mass QTL 37.050.038pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)35318469289878207Rat
2302055Pia30Pristane induced arthritis QTL 303.50.001blood autoantibody amount (VT:0003725)serum immunoglobulin M-type rheumatoid factor level relative to an arbitrary reference serum (CMO:0002111)32793691972936919Rat
1331795Rf30Renal function QTL 303.708urine potassium amount (VT:0010539)urine potassium level (CMO:0000128)33945463789115240Rat
70216Cm14Cardiac mass QTL 142.1heart mass (VT:0007028)heart wet weight (CMO:0000069)331172320163586636Rat
1354589Bw31Body weight QTL 313.3body mass (VT:0001259)body weight (CMO:0000012)33370334778196190Rat
2303593Gluco46Glucose level QTL 463blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)32846857173468571Rat
1354590Despr11Despair related QTL 110.000031locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)32846857173468571Rat
2292591Esta4Estrogen-induced thymic atrophy QTL 4thymus mass (VT:0004954)thymus wet weight (CMO:0000855)347233211147415807Rat
1331777Bw24Body weight QTL 243.503body mass (VT:0001259)body weight (CMO:0000012)33945463789115240Rat
631647Bp122Blood pressure QTL 1226.2arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)33068464275684642Rat
1559282Emca5Estrogen-induced mammary cancer QTL 53.9mammary gland integrity trait (VT:0010552)percentage of study population developing mammary tumors during a period of time (CMO:0000948)343827364169034231Rat
2302276Bw82Body weight QTL 824.32body mass (VT:0001259)body weight (CMO:0000012)33945463762951183Rat
738019Anxrr10Anxiety related response QTL 103.9exploratory behavior trait (VT:0010471)number of entries into a discrete space in an experimental apparatus (CMO:0000960)33851780383517803Rat
9590136Scort3Serum corticosterone level QTL 323.370.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)32824968773249687Rat
10450804Scl70Serum cholesterol level QTL 704.70.001blood LDL cholesterol amount (VT:0000181)blood low density lipoprotein cholesterol level (CMO:0000053)32071409065714090Rat
61419Cia11Collagen induced arthritis QTL 115.6joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)33035677398535386Rat
1354597Kidm13Kidney mass QTL 132.9kidney mass (VT:0002707)right kidney wet weight (CMO:0000082)341874578104104347Rat
8552950Pigfal12Plasma insulin-like growth factor 1 level QTL 127.3blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)32824968773249687Rat
10450794Scl69Serum cholesterol level QTL 696.30.001blood LDL cholesterol amount (VT:0000181)blood low density lipoprotein cholesterol level (CMO:0000053)32071409065714090Rat
8694386Bw159Body weight QTL 1594.520.001body lean mass (VT:0010483)lean tissue morphological measurement (CMO:0002184)32824968773249687Rat
1354604Bw36Body weight QTL 362.9body mass (VT:0001259)body weight (CMO:0000012)333703347104104347Rat
631665Bw8Body weight QTL 85.5body mass (VT:0001259)body weight (CMO:0000012)350437042119183768Rat
2301400Cm68Cardiac mass QTL 680.001heart mass (VT:0007028)heart wet weight to body weight ratio (CMO:0002408)33142640370668733Rat
1358186Ept2Estrogen-induced pituitary tumorigenesis QTL 28.3pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)347233430110362260Rat

Markers in Region
RH136821  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2362,815,442 - 62,815,644 (+)MAPPERmRatBN7.2
mRatBN7.2362,815,442 - 62,815,645 (+)MAPPERmRatBN7.2
Rnor_6.0364,731,358 - 64,731,560NCBIRnor6.0
Rnor_6.06103,932,405 - 103,932,607NCBIRnor6.0
Rnor_5.06112,106,403 - 112,106,605UniSTSRnor5.0
Rnor_5.0371,298,303 - 71,298,505UniSTSRnor5.0
Celera362,293,835 - 62,294,037UniSTS
Cytogenetic Map3q24UniSTS
Cytogenetic Map6q24UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 11 49 113 91 90 59 25 59 6 218 97 93 45 60 31

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001399981 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_001062863 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006224501 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006234425 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008761965 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008761966 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008761967 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008775444 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008775445 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008775446 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063284136 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063284137 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AY325221 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH473949 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ231274 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ231579 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAXUCZ010000003 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSRNOT00000037684   ⟹   ENSRNOP00000039180
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl362,815,230 - 62,850,652 (-)Ensembl
Rnor_6.0 Ensembl364,731,381 - 64,766,472 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000103122   ⟹   ENSRNOP00000095427
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl362,815,230 - 62,850,738 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000104366   ⟹   ENSRNOP00000079427
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl362,802,045 - 62,864,228 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000118363   ⟹   ENSRNOP00000092657
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl362,815,230 - 62,864,228 (-)Ensembl
RefSeq Acc Id: NM_001399981   ⟹   NP_001386910
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8383,222,400 - 83,271,206 (-)NCBI
mRatBN7.2362,815,230 - 62,864,048 (-)NCBI
RefSeq Acc Id: XM_006234425   ⟹   XP_006234487
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8383,222,400 - 83,271,401 (-)NCBI
mRatBN7.2362,815,230 - 62,864,149 (-)NCBI
Rnor_6.0364,731,145 - 64,780,008 (-)NCBI
Rnor_5.0371,298,090 - 71,346,831 (-)NCBI
Sequence:
RefSeq Acc Id: XM_008761965   ⟹   XP_008760187
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8383,222,400 - 83,271,405 (-)NCBI
mRatBN7.2362,815,230 - 62,864,149 (-)NCBI
Rnor_6.0364,731,145 - 64,780,009 (-)NCBI
Sequence:
RefSeq Acc Id: XM_008761966   ⟹   XP_008760188
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8383,222,400 - 83,271,427 (-)NCBI
mRatBN7.2362,815,230 - 62,864,269 (-)NCBI
Rnor_6.0364,731,145 - 64,780,127 (-)NCBI
Sequence:
RefSeq Acc Id: XM_008761967   ⟹   XP_008760189
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8383,222,400 - 83,271,401 (-)NCBI
mRatBN7.2362,815,230 - 62,864,149 (-)NCBI
Rnor_6.0364,731,145 - 64,780,009 (-)NCBI
Sequence:
RefSeq Acc Id: XM_063284136   ⟹   XP_063140206
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8383,222,400 - 83,271,401 (-)NCBI
RefSeq Acc Id: XM_063284137   ⟹   XP_063140207
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8383,233,889 - 83,271,401 (-)NCBI
RefSeq Acc Id: XP_006234487   ⟸   XM_006234425
- Peptide Label: isoform X3
- UniProtKB: A0A8I6GJW5 (UniProtKB/TrEMBL),   F1LY38 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_008760188   ⟸   XM_008761966
- Peptide Label: isoform X1
- UniProtKB: F1LY38 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_008760189   ⟸   XM_008761967
- Peptide Label: isoform X2
- UniProtKB: F1LY38 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_008760187   ⟸   XM_008761965
- Peptide Label: isoform X1
- UniProtKB: F1LY38 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000039180   ⟸   ENSRNOT00000037684
Ensembl Acc Id: ENSRNOP00000079427   ⟸   ENSRNOT00000104366
Ensembl Acc Id: ENSRNOP00000095427   ⟸   ENSRNOT00000103122
Ensembl Acc Id: ENSRNOP00000092657   ⟸   ENSRNOT00000118363
RefSeq Acc Id: NP_001386910   ⟸   NM_001399981
- UniProtKB: A6HMK0 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063140206   ⟸   XM_063284136
- Peptide Label: isoform X4
- UniProtKB: A6HMK0 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063140207   ⟸   XM_063284137
- Peptide Label: isoform X5
Protein Domains
MI

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-F1LY38-F1-model_v2 AlphaFold F1LY38 1-874 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1565385 AgrOrtholog
BioCyc Gene G2FUF-49259 BioCyc
Ensembl Genes ENSRNOG00000012651 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000037684.7 UniProtKB/TrEMBL
  ENSRNOT00000103122.1 UniProtKB/TrEMBL
  ENSRNOT00000104366.1 UniProtKB/TrEMBL
  ENSRNOT00000118363.1 UniProtKB/TrEMBL
Gene3D-CATH 1.25.40.180 UniProtKB/TrEMBL
InterPro ARM-type_fold UniProtKB/TrEMBL
  CWC22_splicing_factor UniProtKB/TrEMBL
  Initiation_fac_eIF4g_MI UniProtKB/TrEMBL
  MIF4G-like_typ-3 UniProtKB/TrEMBL
NCBI Gene 362153 ENTREZGENE
PANTHER CELL CYCLE CONTROL PROTEIN CWF22-RELATED UniProtKB/TrEMBL
  PRE-MRNA-SPLICING FACTOR CWC22 HOMOLOG UniProtKB/TrEMBL
Pfam MA3 UniProtKB/TrEMBL
  MIF4G UniProtKB/TrEMBL
PhenoGen Cwc22 PhenoGen
PROSITE PS51366 UniProtKB/TrEMBL
RatGTEx ENSRNOG00000012651 RatGTEx
SMART MA3 UniProtKB/TrEMBL
  MIF4G UniProtKB/TrEMBL
Superfamily-SCOP ARM-type_fold UniProtKB/TrEMBL
UniProt A0A8I6AJM5_RAT UniProtKB/TrEMBL
  A0A8I6G3A2_RAT UniProtKB/TrEMBL
  A0A8I6GJW5 ENTREZGENE, UniProtKB/TrEMBL
  A6HMK0 ENTREZGENE, UniProtKB/TrEMBL
  F1LY38 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2022-03-29 Cwc22  CWC22 spliceosome associated protein  Cwc22  CWC22 spliceosome associated protein homolog  Name changed 629549 APPROVED
2016-08-18 Cwc22  CWC22 spliceosome associated protein homolog  Cwc22  CWC22 homolog, spliceosome-associated protein  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2015-11-12 Cwc22  CWC22 homolog, spliceosome-associated protein  Cwc22  CWC22 spliceosome-associated protein  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2014-07-09 Cwc22  CWC22 spliceosome-associated protein  Cwc22  CWC22 spliceosome-associated protein homolog (S. cerevisiae)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2009-06-12 Cwc22  CWC22 spliceosome-associated protein homolog (S. cerevisiae)  RGD1565385  similar to mKIAA1604 protein   Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-04-30 RGD1565385  similar to mKIAA1604 protein   RGD1565385_predicted  similar to mKIAA1604 protein (predicted)  'predicted' is removed 2292626 APPROVED
2006-03-07 RGD1565385_predicted  similar to mKIAA1604 protein (predicted)  LOC362153  similar to mKIAA1604 protein  Symbol and Name status set to approved 1299863 APPROVED
2006-02-09 LOC362153  similar to mKIAA1604 protein      Symbol and Name status set to provisional 70820 PROVISIONAL