Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Object Symbol | Species | Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | Taok3 | Rat | (-)-epigallocatechin 3-gallate | multiple interactions | ISO | TAOK3 (Homo sapiens) | 6480464 | [potassium chromate(VI) co-treated with epigallocatechin gallate] results in decreased expression of TAOK3 mRNA | CTD | PMID:22079256 | Taok3 | Rat | (1->4)-beta-D-glucan | multiple interactions | ISO | Taok3 (Mus musculus) | 6480464 | [perfluorooctane sulfonic acid co-treated with Cellulose] results in decreased expression of TAOK3 mRNA | CTD | PMID:36331819 | Taok3 | Rat | 1,1-dichloroethene | increases expression | ISO | Taok3 (Mus musculus) | 6480464 | vinylidene chloride results in increased expression of TAOK3 mRNA | CTD | PMID:26682919 | Taok3 | Rat | 1,2-dichloroethane | decreases expression | ISO | Taok3 (Mus musculus) | 6480464 | ethylene dichloride results in decreased expression of TAOK3 mRNA | CTD | PMID:28960355 | Taok3 | Rat | 1,2-dimethylhydrazine | increases expression | ISO | Taok3 (Mus musculus) | 6480464 | 1 and 2-Dimethylhydrazine results in increased expression of TAOK3 mRNA | CTD | PMID:22206623 | Taok3 | Rat | 17beta-hydroxy-5alpha-androstan-3-one | increases expression | ISO | TAOK3 (Homo sapiens) | 6480464 | Dihydrotestosterone results in increased expression of TAOK3 mRNA | CTD | PMID:29581250 | Taok3 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | EXP | | 6480464 | Tetrachlorodibenzodioxin affects the expression of TAOK3 mRNA | CTD | PMID:22298810 and PMID:34747641 | Taok3 | Rat | 2,4-dinitrotoluene | affects expression | EXP | | 6480464 | 2 and 4-dinitrotoluene affects the expression of TAOK3 mRNA | CTD | PMID:21346803 | Taok3 | Rat | 2-hydroxypropanoic acid | decreases expression | ISO | TAOK3 (Homo sapiens) | 6480464 | Lactic Acid results in decreased expression of TAOK3 mRNA | CTD | PMID:30851411 | Taok3 | Rat | 3,4-methylenedioxymethamphetamine | decreases expression | ISO | Taok3 (Mus musculus) | 6480464 | N-Methyl-3 and 4-methylenedioxyamphetamine results in decreased expression of TAOK3 mRNA | CTD | PMID:26251327 | Taok3 | Rat | 4,4'-diaminodiphenylmethane | decreases expression | ISO | Taok3 (Mus musculus) | 6480464 | 4 and 4'-diaminodiphenylmethane results in decreased expression of TAOK3 mRNA | CTD | PMID:18648102 | Taok3 | Rat | 4,4'-sulfonyldiphenol | affects methylation | ISO | Taok3 (Mus musculus) | 6480464 | bisphenol S affects the methylation of TAOK3 gene | CTD | PMID:31683443 | Taok3 | Rat | 5-fluorouracil | affects response to substance | ISO | TAOK3 (Homo sapiens) | 6480464 | TAOK3 protein affects the susceptibility to Fluorouracil | CTD | PMID:15548681 | Taok3 | Rat | 6-propyl-2-thiouracil | decreases expression | EXP | | 6480464 | Propylthiouracil results in decreased expression of TAOK3 mRNA | CTD | PMID:24780913 | Taok3 | Rat | acrylamide | increases expression | ISO | TAOK3 (Homo sapiens) | 6480464 | Acrylamide results in increased expression of TAOK3 mRNA | CTD | PMID:32763439 | Taok3 | Rat | amphetamine | decreases expression | EXP | | 6480464 | Amphetamine results in decreased expression of TAOK3 mRNA | CTD | PMID:30779732 | Taok3 | Rat | aristolochic acid A | decreases expression | ISO | TAOK3 (Homo sapiens) | 6480464 | aristolochic acid I results in decreased expression of TAOK3 mRNA | CTD | PMID:33212167 | Taok3 | Rat | belinostat | increases expression | ISO | TAOK3 (Homo sapiens) | 6480464 | belinostat results in increased expression of TAOK3 mRNA | CTD | PMID:26272509 | Taok3 | Rat | benzo[a]pyrene | decreases expression | ISO | TAOK3 (Homo sapiens) | 6480464 | Benzo(a)pyrene results in decreased expression of TAOK3 mRNA | CTD | PMID:20106945 and PMID:21632981 | Taok3 | Rat | benzo[a]pyrene | affects methylation | ISO | TAOK3 (Homo sapiens) | 6480464 | Benzo(a)pyrene affects the methylation of TAOK3 5' UTR and Benzo(a)pyrene affects the methylation of TAOK3 intron | CTD | PMID:27901495 and PMID:30157460 | Taok3 | Rat | bisphenol A | decreases expression | ISO | Taok3 (Mus musculus) | 6480464 | bisphenol A results in decreased expression of TAOK3 mRNA | CTD | PMID:21932408 and PMID:33221593 | Taok3 | Rat | bisphenol A | increases expression | EXP | | 6480464 | bisphenol A results in increased expression of TAOK3 mRNA | CTD | PMID:30816183 and PMID:32528016 | Taok3 | Rat | bisphenol A | increases methylation | EXP | | 6480464 | bisphenol A results in increased methylation of TAOK3 gene | CTD | PMID:28505145 | Taok3 | Rat | bisphenol A | decreases expression | EXP | | 6480464 | bisphenol A results in decreased expression of TAOK3 mRNA | CTD | PMID:25181051 and PMID:34947998 | Taok3 | Rat | bisphenol A | increases expression | ISO | Taok3 (Mus musculus) | 6480464 | bisphenol A results in increased expression of TAOK3 mRNA | CTD | PMID:26063408 | Taok3 | Rat | Bisphenol A diglycidyl ether | affects splicing | ISO | Taok3 (Mus musculus) | 6480464 | 2 and 2-bis(4-glycidyloxyphenyl)propane affects the splicing of TAOK3 mRNA | CTD | PMID:36464114 | Taok3 | Rat | cadmium atom | multiple interactions | ISO | TAOK3 (Homo sapiens) | 6480464 | [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of TAOK3 mRNA | CTD | PMID:35301059 | Taok3 | Rat | cadmium dichloride | multiple interactions | ISO | TAOK3 (Homo sapiens) | 6480464 | [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of TAOK3 mRNA | CTD | PMID:35301059 | Taok3 | Rat | calcitriol | increases expression | ISO | TAOK3 (Homo sapiens) | 6480464 | Calcitriol results in increased expression of TAOK3 mRNA | CTD | PMID:16002434 | Taok3 | Rat | carbamazepine | affects expression | ISO | TAOK3 (Homo sapiens) | 6480464 | Carbamazepine affects the expression of TAOK3 mRNA | CTD | PMID:25979313 | Taok3 | Rat | celastrol | decreases expression | ISO | TAOK3 (Homo sapiens) | 6480464 | celastrol results in decreased expression of TAOK3 mRNA | CTD | PMID:17010675 | Taok3 | Rat | cobalt dichloride | increases expression | ISO | Taok3 (Mus musculus) | 6480464 | cobaltous chloride results in increased expression of TAOK3 mRNA | CTD | PMID:21139344 | Taok3 | Rat | coumarin | increases phosphorylation | ISO | TAOK3 (Homo sapiens) | 6480464 | coumarin results in increased phosphorylation of TAOK3 protein | CTD | PMID:35688186 | Taok3 | Rat | coumestrol | multiple interactions | ISO | TAOK3 (Homo sapiens) | 6480464 | [Coumestrol co-treated with 2 and 3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of TAOK3 mRNA | CTD | PMID:19167446 | Taok3 | Rat | coumestrol | decreases expression | ISO | TAOK3 (Homo sapiens) | 6480464 | Coumestrol results in decreased expression of TAOK3 mRNA | CTD | PMID:19167446 | Taok3 | Rat | diuron | decreases expression | EXP | | 6480464 | Diuron results in decreased expression of TAOK3 mRNA | CTD | PMID:21551480 | Taok3 | Rat | dorsomorphin | multiple interactions | ISO | TAOK3 (Homo sapiens) | 6480464 | [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1 more ... | CTD | PMID:27188386 | Taok3 | Rat | emodin | decreases expression | ISO | TAOK3 (Homo sapiens) | 6480464 | Emodin results in decreased expression of TAOK3 mRNA | CTD | PMID:16045814 | Taok3 | Rat | endosulfan | decreases expression | EXP | | 6480464 | Endosulfan results in decreased expression of TAOK3 mRNA | CTD | PMID:29391264 | Taok3 | Rat | Enterolactone | multiple interactions | ISO | TAOK3 (Homo sapiens) | 6480464 | [Coumestrol co-treated with 2 and 3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of TAOK3 mRNA | CTD | PMID:19167446 | Taok3 | Rat | ethanol | decreases response to substance | ISO | Taok3 (Mus musculus) | 6480464 | TAOK3 gene mutant form results in decreased susceptibility to Ethanol | CTD | PMID:23227189 | Taok3 | Rat | FR900359 | affects phosphorylation | ISO | TAOK3 (Homo sapiens) | 6480464 | FR900359 affects the phosphorylation of TAOK3 protein | CTD | PMID:37730182 | Taok3 | Rat | furan | increases methylation | EXP | | 6480464 | furan results in increased methylation of TAOK3 gene | CTD | PMID:22079235 | Taok3 | Rat | furan | decreases expression | EXP | | 6480464 | furan results in decreased expression of TAOK3 mRNA | CTD | PMID:26194646 | Taok3 | Rat | gedunin | decreases expression | ISO | TAOK3 (Homo sapiens) | 6480464 | gedunin results in decreased expression of TAOK3 mRNA | CTD | PMID:17010675 | Taok3 | Rat | gentamycin | increases expression | EXP | | 6480464 | Gentamicins results in increased expression of TAOK3 mRNA | CTD | PMID:33387578 | Taok3 | Rat | glycidol | increases expression | EXP | | 6480464 | glycidol results in increased expression of TAOK3 mRNA | CTD | PMID:24915197 | Taok3 | Rat | inulin | multiple interactions | ISO | Taok3 (Mus musculus) | 6480464 | [perfluorooctane sulfonic acid co-treated with Inulin] results in decreased expression of TAOK3 mRNA | CTD | PMID:36331819 | Taok3 | Rat | ivermectin | decreases expression | ISO | TAOK3 (Homo sapiens) | 6480464 | Ivermectin results in decreased expression of TAOK3 protein | CTD | PMID:32959892 | Taok3 | Rat | methoxychlor | affects methylation | EXP | | 6480464 | Methoxychlor affects the methylation of TAOK3 gene | CTD | PMID:35440735 | Taok3 | Rat | Nor-9-carboxy-delta9-THC | multiple interactions | ISO | TAOK3 (Homo sapiens) | 6480464 | [Cannabinoids results in increased abundance of 11-nor-delta(9)-tetrahydrocannabinol-9-carboxylic acid] which affects the methylation of TAOK3 gene | CTD | PMID:30521419 | Taok3 | Rat | paracetamol | increases expression | ISO | Taok3 (Mus musculus) | 6480464 | Acetaminophen results in increased expression of TAOK3 mRNA | CTD | PMID:17585979 | Taok3 | Rat | paracetamol | increases expression | EXP | | 6480464 | Acetaminophen results in increased expression of TAOK3 mRNA | CTD | PMID:33387578 | Taok3 | Rat | paracetamol | increases expression | ISO | TAOK3 (Homo sapiens) | 6480464 | Acetaminophen results in increased expression of TAOK3 mRNA | CTD | PMID:25704631 and PMID:29067470 | Taok3 | Rat | perfluorooctane-1-sulfonic acid | multiple interactions | ISO | Taok3 (Mus musculus) | 6480464 | [perfluorooctane sulfonic acid co-treated with Cellulose] results in decreased expression of TAOK3 mRNA more ... | CTD | PMID:36331819 | Taok3 | Rat | phenobarbital | decreases expression | ISO | Taok3 (Mus musculus) | 6480464 | Phenobarbital results in decreased expression of TAOK3 mRNA | CTD | PMID:19270015 and PMID:23091169 | Taok3 | Rat | phenylmercury acetate | increases expression | ISO | TAOK3 (Homo sapiens) | 6480464 | Phenylmercuric Acetate results in increased expression of TAOK3 mRNA | CTD | PMID:26272509 | Taok3 | Rat | phenylmercury acetate | multiple interactions | ISO | TAOK3 (Homo sapiens) | 6480464 | [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of TAOK3 mRNA | CTD | PMID:27188386 | Taok3 | Rat | potassium chromate | multiple interactions | ISO | TAOK3 (Homo sapiens) | 6480464 | [potassium chromate(VI) co-treated with epigallocatechin gallate] results in decreased expression of TAOK3 mRNA | CTD | PMID:22079256 | Taok3 | Rat | potassium chromate | decreases expression | ISO | TAOK3 (Homo sapiens) | 6480464 | potassium chromate(VI) results in decreased expression of TAOK3 mRNA | CTD | PMID:22079256 | Taok3 | Rat | pregnenolone 16alpha-carbonitrile | decreases expression | ISO | Taok3 (Mus musculus) | 6480464 | Pregnenolone Carbonitrile results in decreased expression of TAOK3 mRNA | CTD | PMID:28903501 | Taok3 | Rat | propiconazole | decreases expression | ISO | Taok3 (Mus musculus) | 6480464 | propiconazole results in decreased expression of TAOK3 mRNA | CTD | PMID:21278054 | Taok3 | Rat | quercetin | decreases expression | ISO | TAOK3 (Homo sapiens) | 6480464 | Quercetin results in decreased expression of TAOK3 mRNA | CTD | PMID:21632981 | Taok3 | Rat | rac-lactic acid | decreases expression | ISO | TAOK3 (Homo sapiens) | 6480464 | Lactic Acid results in decreased expression of TAOK3 mRNA | CTD | PMID:30851411 | Taok3 | Rat | raloxifene | increases expression | ISO | TAOK3 (Homo sapiens) | 6480464 | Raloxifene Hydrochloride results in increased expression of TAOK3 mRNA | CTD | PMID:19429434 | Taok3 | Rat | resveratrol | multiple interactions | ISO | TAOK3 (Homo sapiens) | 6480464 | [Plant Extracts co-treated with Resveratrol] results in increased expression of TAOK3 mRNA | CTD | PMID:23557933 | Taok3 | Rat | rotenone | decreases expression | EXP | | 6480464 | Rotenone results in decreased expression of TAOK3 mRNA | CTD | PMID:19013527 | Taok3 | Rat | SB 431542 | multiple interactions | ISO | TAOK3 (Homo sapiens) | 6480464 | [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1 more ... | CTD | PMID:27188386 | Taok3 | Rat | sodium arsenite | decreases expression | ISO | TAOK3 (Homo sapiens) | 6480464 | sodium arsenite results in decreased expression of TAOK3 mRNA and sodium arsenite results in decreased expression of TAOK3 protein | CTD | PMID:30528433 and PMID:34032870 | Taok3 | Rat | sodium arsenite | decreases expression | ISO | Taok3 (Mus musculus) | 6480464 | sodium arsenite results in decreased expression of TAOK3 mRNA | CTD | PMID:37682722 | Taok3 | Rat | sodium arsenite | increases expression | ISO | Taok3 (Mus musculus) | 6480464 | sodium arsenite results in increased expression of TAOK3 mRNA | CTD | PMID:36209798 | Taok3 | Rat | tamoxifen | increases expression | ISO | TAOK3 (Homo sapiens) | 6480464 | Tamoxifen results in increased expression of TAOK3 mRNA | CTD | PMID:19429434 | Taok3 | Rat | Tesaglitazar | decreases expression | EXP | | 6480464 | tesaglitazar results in decreased expression of TAOK3 mRNA | CTD | PMID:21515302 | Taok3 | Rat | tetrachloromethane | decreases expression | EXP | | 6480464 | Carbon Tetrachloride results in decreased expression of TAOK3 mRNA | CTD | PMID:30690589 and PMID:31150632 | Taok3 | Rat | tetrachloromethane | increases methylation | EXP | | 6480464 | Carbon Tetrachloride results in increased methylation of TAOK3 promoter | CTD | PMID:30690589 | Taok3 | Rat | thioacetamide | decreases expression | EXP | | 6480464 | Thioacetamide results in decreased expression of TAOK3 mRNA | CTD | PMID:23411599 | Taok3 | Rat | thiram | increases expression | ISO | TAOK3 (Homo sapiens) | 6480464 | Thiram results in increased expression of TAOK3 mRNA | CTD | PMID:38568856 | Taok3 | Rat | titanium dioxide | decreases methylation | ISO | Taok3 (Mus musculus) | 6480464 | titanium dioxide results in decreased methylation of TAOK3 gene and titanium dioxide results in decreased methylation of TAOK3 promoter alternative form | CTD | PMID:35295148 | Taok3 | Rat | titanium dioxide | decreases methylation | ISO | TAOK3 (Homo sapiens) | 6480464 | titanium dioxide results in decreased methylation of TAOK3 gene | CTD | PMID:34973136 | Taok3 | Rat | trichloroethene | increases methylation | EXP | | 6480464 | Trichloroethylene results in increased methylation of TAOK3 gene | CTD | PMID:27618143 | Taok3 | Rat | trichloroethene | increases expression | EXP | | 6480464 | Trichloroethylene results in increased expression of TAOK3 mRNA | CTD | PMID:33387578 | Taok3 | Rat | trichostatin A | increases expression | ISO | TAOK3 (Homo sapiens) | 6480464 | trichostatin A results in increased expression of TAOK3 mRNA | CTD | PMID:24935251 | Taok3 | Rat | trichostatin A | affects expression | ISO | TAOK3 (Homo sapiens) | 6480464 | trichostatin A affects the expression of TAOK3 mRNA | CTD | PMID:28542535 | Taok3 | Rat | triptonide | affects expression | ISO | Taok3 (Mus musculus) | 6480464 | triptonide affects the expression of TAOK3 mRNA | CTD | PMID:33045310 | Taok3 | Rat | troglitazone | decreases expression | ISO | Taok3 (Mus musculus) | 6480464 | troglitazone results in decreased expression of TAOK3 mRNA | CTD | PMID:28973697 | Taok3 | Rat | tungsten | decreases expression | ISO | Taok3 (Mus musculus) | 6480464 | Tungsten results in decreased expression of TAOK3 mRNA | CTD | PMID:30912803 | Taok3 | Rat | urethane | increases expression | ISO | TAOK3 (Homo sapiens) | 6480464 | Urethane results in increased expression of TAOK3 mRNA | CTD | PMID:28818685 | Taok3 | Rat | valproic acid | decreases methylation | ISO | TAOK3 (Homo sapiens) | 6480464 | Valproic Acid results in decreased methylation of TAOK3 gene | CTD | PMID:29154799 | Taok3 | Rat | valproic acid | affects expression | ISO | TAOK3 (Homo sapiens) | 6480464 | Valproic Acid affects the expression of TAOK3 mRNA | CTD | PMID:25979313 | Taok3 | Rat | valproic acid | increases expression | ISO | TAOK3 (Homo sapiens) | 6480464 | Valproic Acid results in increased expression of TAOK3 mRNA | CTD | PMID:22083351 more ... | Taok3 | Rat | valproic acid | multiple interactions | ISO | TAOK3 (Homo sapiens) | 6480464 | [NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of TAOK3 mRNA | CTD | PMID:27188386 | Taok3 | Rat | vinclozolin | increases methylation | EXP | | 6480464 | vinclozolin results in increased methylation of TAOK3 gene | CTD | PMID:31079544 | Taok3 | Rat | vorinostat | increases expression | ISO | TAOK3 (Homo sapiens) | 6480464 | vorinostat results in increased expression of TAOK3 mRNA | CTD | PMID:22083351 | |