Ptprd (protein tyrosine phosphatase, receptor type, D) - Rat Genome Database

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Gene: Ptprd (protein tyrosine phosphatase, receptor type, D) Rattus norvegicus
Analyze
Symbol: Ptprd
Name: protein tyrosine phosphatase, receptor type, D
RGD ID: 1561090
Description: Predicted to enable cell adhesion molecule binding activity; protein tyrosine phosphatase activity; and signaling receptor binding activity. Involved in several processes, including cellular response to platelet-derived growth factor stimulus; regulation of postsynaptic density assembly; and synaptic membrane adhesion. Is active in glutamatergic synapse. Biomarker of restless legs syndrome. Human ortholog(s) of this gene implicated in coronary artery disease; diabetes mellitus; hypertension; and type 2 diabetes mellitus. Orthologous to human PTPRD (protein tyrosine phosphatase receptor type D); INTERACTS WITH (+)-schisandrin B; 1-naphthyl isothiocyanate; 17alpha-ethynylestradiol.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: LOC103692382; LOC313278; receptor-type tyrosine-protein phosphatase delta; RGD1561090; similar to protein tyrosine phosphatase, receptor type, D; uncharacterized LOC103692382
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8595,093,221 - 97,415,498 (-)NCBIGRCr8
mRatBN7.2591,122,354 - 91,641,754 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2590,046,993 - 90,698,977 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl590,048,966 - 92,369,396 (-)EnsemblmRatBN7.2 Ensembl
Rnor_6.0592,862,229 - 93,514,071 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl592,862,267 - 93,244,202 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0596,907,323 - 97,286,547 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4594,069,724 - 94,286,657 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera588,728,402 - 89,389,021 (-)NCBICelera
Cytogenetic Map5q31NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-schisandrin B  (EXP)
(1->4)-beta-D-glucan  (ISO)
1,2-dichloroethane  (ISO)
1,2-dimethylhydrazine  (ISO)
1-naphthyl isothiocyanate  (EXP)
17alpha-ethynylestradiol  (EXP)
2,2',4,4',5,5'-hexachlorobiphenyl  (EXP)
2,2',4,4'-Tetrabromodiphenyl ether  (EXP)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,3,7,8-Tetrachlorodibenzofuran  (EXP)
2,4-dinitrotoluene  (EXP)
2,6-dinitrotoluene  (EXP)
2-butoxyethanol  (ISO)
3,3',4,4',5-pentachlorobiphenyl  (EXP)
3,4-methylenedioxymethamphetamine  (ISO)
3-chloropropane-1,2-diol  (EXP)
4,4'-diaminodiphenylmethane  (EXP)
4-hydroxyphenyl retinamide  (ISO)
aflatoxin B1  (ISO)
Aflatoxin B2 alpha  (ISO)
all-trans-retinoic acid  (ISO)
aristolochic acid A  (ISO)
benzo[a]pyrene  (ISO)
benzo[e]pyrene  (ISO)
bis(2-chloroethyl) sulfide  (EXP)
bisphenol A  (EXP,ISO)
butanal  (ISO)
cadmium dichloride  (EXP)
calcitriol  (ISO)
casticin  (ISO)
CGP 52608  (ISO)
chloroprene  (EXP)
choline  (ISO)
cisplatin  (EXP)
clofibrate  (ISO)
clofibric acid  (EXP)
cumene  (ISO)
cyclosporin A  (ISO)
dexamethasone  (ISO)
diazinon  (EXP)
dibutyl phthalate  (ISO)
dioxygen  (EXP,ISO)
dorsomorphin  (ISO)
doxorubicin  (ISO)
endosulfan  (EXP)
ethanol  (ISO)
flutamide  (EXP)
folic acid  (ISO)
furan  (EXP)
geldanamycin  (ISO)
Heliotrine  (ISO)
irinotecan  (ISO)
isoprenaline  (ISO)
ivermectin  (ISO)
L-methionine  (ISO)
manganese(II) chloride  (EXP)
methapyrilene  (ISO)
mono(2-ethylhexyl) phthalate  (ISO)
N-nitrosodiethylamine  (EXP)
N-nitrosodimethylamine  (EXP)
nefazodone  (EXP)
nickel atom  (ISO)
nimesulide  (EXP)
O-methyleugenol  (ISO)
oxaliplatin  (EXP)
ozone  (ISO)
paracetamol  (EXP,ISO)
paraquat  (EXP)
pentachlorophenol  (ISO)
perfluorooctane-1-sulfonic acid  (ISO)
perfluorooctanoic acid  (EXP,ISO)
phenobarbital  (EXP,ISO)
pirinixic acid  (ISO)
pramipexole  (EXP)
pregnenolone 16alpha-carbonitrile  (EXP,ISO)
propiconazole  (ISO)
rotenone  (EXP)
SB 431542  (ISO)
senecionine  (ISO)
Senkirkine  (ISO)
silicon dioxide  (ISO)
sodium arsenite  (ISO)
sodium dichromate  (EXP)
streptozocin  (EXP)
temozolomide  (ISO)
testosterone enanthate  (ISO)
tetrachloromethane  (EXP,ISO)
thapsigargin  (ISO)
thioacetamide  (EXP)
titanium dioxide  (ISO)
toluene  (EXP)
topotecan  (EXP)
trichostatin A  (ISO)
trimellitic anhydride  (ISO)
triptonide  (ISO)
valdecoxib  (EXP)
valproic acid  (EXP,ISO)
vancomycin  (ISO)
vinclozolin  (EXP)
vitamin E  (ISO)
vorinostat  (ISO)
zinc atom  (EXP)
zinc sulfate  (EXP)
zinc(0)  (EXP)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Replication of genome-wide association signals of type 2 diabetes in Han Chinese in a prospective cohort. Chang YC, etal., Clin Endocrinol (Oxf). 2012 Mar;76(3):365-72. doi: 10.1111/j.1365-2265.2011.04175.x.
2. SALM5 trans-synaptically interacts with LAR-RPTPs in a splicing-dependent manner to regulate synapse development. Choi Y, etal., Sci Rep. 2016 May 26;6:26676. doi: 10.1038/srep26676.
3. Genome-wide association analysis of common genetic variants of resistant hypertension. El Rouby N, etal., Pharmacogenomics J. 2019 Jun;19(3):295-304. doi: 10.1038/s41397-018-0049-x. Epub 2018 Sep 20.
4. Air pollution and diabetes association: Modification by type 2 diabetes genetic risk score. Eze IC, etal., Environ Int. 2016 Sep;94:263-271. doi: 10.1016/j.envint.2016.04.032. Epub 2016 Jun 6.
5. Astrocyte-Secreted Glypican 4 Regulates Release of Neuronal Pentraxin 1 from Axons to Induce Functional Synapse Formation. Farhy-Tselnicker I, etal., Neuron. 2017 Oct 11;96(2):428-445.e13. doi: 10.1016/j.neuron.2017.09.053.
6. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
7. PTPRD gene associated with blood pressure response to atenolol and resistant hypertension. Gong Y, etal., J Hypertens. 2015 Nov;33(11):2278-85. doi: 10.1097/HJH.0000000000000714.
8. Trans-synaptic adhesions between netrin-G ligand-3 (NGL-3) and receptor tyrosine phosphatases LAR, protein-tyrosine phosphatase delta (PTPdelta), and PTPsigma via specific domains regulate excitatory synapse formation. Kwon SK, etal., J Biol Chem. 2010 Apr 30;285(18):13966-78. doi: 10.1074/jbc.M109.061127. Epub 2010 Feb 6.
9. Protein tyrosine phosphatase receptor type delta (PTPRD) gene in an animal model of restless legs syndrome. Morais MA, etal., J Sleep Res. 2023 Apr;32(2):e13716. doi: 10.1111/jsr.13716. Epub 2022 Sep 2.
10. Effectiveness of exercise and pramipexole in the treatment of restless leg syndrome: Implications on the dopaminergic system and PTPRD. Morais MA, etal., Sleep Med. 2023 Oct;110:201-211. doi: 10.1016/j.sleep.2023.08.012. Epub 2023 Aug 19.
11. GOA pipeline RGD automated data pipeline
12. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
13. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
14. Large scale association analysis identifies three susceptibility loci for coronary artery disease. Saade S, etal., PLoS One. 2011;6(12):e29427. doi: 10.1371/journal.pone.0029427. Epub 2011 Dec 27.
15. Methylation-mediated silencing of PTPRD induces pulmonary hypertension by promoting pulmonary arterial smooth muscle cell migration via the PDGFRB/PLCγ1 axis. Xu J, etal., J Hypertens. 2022 Sep 1;40(9):1795-1807. doi: 10.1097/HJH.0000000000003220. Epub 2022 Jul 25.
Additional References at PubMed
PMID:10856223   PMID:21926414   PMID:21940441   PMID:22357843   PMID:23345436   PMID:23533145   PMID:24843164   PMID:25908590   PMID:25989451  


Genomics

Comparative Map Data
Ptprd
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8595,093,221 - 97,415,498 (-)NCBIGRCr8
mRatBN7.2591,122,354 - 91,641,754 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2590,046,993 - 90,698,977 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl590,048,966 - 92,369,396 (-)EnsemblmRatBN7.2 Ensembl
Rnor_6.0592,862,229 - 93,514,071 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl592,862,267 - 93,244,202 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0596,907,323 - 97,286,547 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4594,069,724 - 94,286,657 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera588,728,402 - 89,389,021 (-)NCBICelera
Cytogenetic Map5q31NCBI
PTPRD
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3898,314,246 - 10,613,002 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl98,314,246 - 10,613,002 (-)EnsemblGRCh38hg38GRCh38
GRCh3798,314,246 - 10,613,002 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 3698,304,246 - 10,602,509 (-)NCBINCBI36Build 36hg18NCBI36
Build 3498,307,267 - 9,008,737NCBI
Celera98,248,560 - 10,545,456 (-)NCBICelera
Cytogenetic Map9p24.1-p23NCBI
HuRef98,274,893 - 10,576,645 (-)NCBIHuRef
CHM1_198,314,050 - 10,612,534 (-)NCBICHM1_1
T2T-CHM13v2.098,320,802 - 10,622,316 (-)NCBIT2T-CHM13v2.0
Ptprd
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39475,859,474 - 78,132,282 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl475,859,475 - 78,130,198 (-)EnsemblGRCm39 Ensembl
GRCm38475,941,237 - 78,211,742 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl475,941,238 - 78,211,961 (-)EnsemblGRCm38mm10GRCm38
MGSCv37475,587,143 - 76,240,203 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36475,416,037 - 76,065,530 (-)NCBIMGSCv36mm8
Celera474,401,961 - 75,072,056 (-)NCBICelera
Cytogenetic Map4C3NCBI
cM Map436.94NCBI
Ptprd
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495543412,031,420 - 12,428,774 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495543412,033,825 - 14,132,636 (-)NCBIChiLan1.0ChiLan1.0
PTPRD
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v211113,968,495 - 116,276,594 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan19113,974,448 - 116,282,540 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v098,113,171 - 10,420,732 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.198,284,946 - 10,587,642 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl98,288,569 - 8,831,227 (-)Ensemblpanpan1.1panPan2
PTPRD
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11129,100,913 - 31,278,495 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1129,104,448 - 29,501,600 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1127,899,386 - 28,554,986 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01129,983,665 - 32,164,492 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1129,983,093 - 30,381,977 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11128,699,584 - 30,884,051 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01128,519,644 - 30,692,371 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01129,185,571 - 31,348,978 (-)NCBIUU_Cfam_GSD_1.0
Ptprd
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404947144,112,128 - 146,247,876 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365392,564,793 - 2,945,293 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365392,564,815 - 3,369,975 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PTPRD
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1213,483,348 - 214,009,893 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11211,832,409 - 214,013,013 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
PTPRD
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11270,160,253 - 71,237,292 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1270,693,214 - 71,239,437 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603857,226,835 - 59,559,270 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Ptprd
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473612,874,706 - 13,278,956 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462473612,874,884 - 13,558,030 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Ptprd
3896 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:514
Count of miRNA genes:115
Interacting mature miRNAs:123
Transcripts:ENSRNOT00000008897, ENSRNOT00000025426, ENSRNOT00000066046, ENSRNOT00000071089, ENSRNOT00000074491, ENSRNOT00000075474
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1331756Rf34Renal function QTL 344.16275kidney blood vessel physiology trait (VT:0100012)absolute change in renal blood flow rate (CMO:0001168)5190450412Rat
70212Niddm25Non-insulin dependent diabetes mellitus QTL 253.54blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)51131345958Rat
1576314Eutr1Estrogen induced uterine response QTL 1uterus integrity trait (VT:0010575)pyometritis severity score (CMO:0002009)52138965166875058Rat
7394712Emca13Estrogen-induced mammary cancer QTL 13mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)5982326699753708Rat
634305Mamtr1Mammary tumor resistance QTL 10.0001mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)512789751113558310Rat
2290448Scl54Serum cholesterol level QTL 542.93blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)531663789131345958Rat
1576317Eutr2Estrogen induced uterine response QTL 20.01uterus integrity trait (VT:0010575)pyometritis severity score (CMO:0002009)534730116104251008Rat
2316959Gluco59Glucose level QTL 594.7blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)534944474113558310Rat
1641912Alcrsp18Alcohol response QTL 18response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)535189153141643988Rat
1549845Scl44Serum cholesterol level QTL 446blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)540128307148607290Rat
1331801Rf33Renal function QTL 334.149kidney blood vessel physiology trait (VT:0100012)absolute change in renal vascular resistance (CMO:0001900)543726656129132602Rat
1578766Tcas11Tongue tumor susceptibility QTL 114.12tongue integrity trait (VT:0010553)number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)546711509161317411Rat
1300115Hrtrt7Heart rate QTL 72.76heart pumping trait (VT:2000009)heart rate (CMO:0000002)54786906290099692Rat
9589025Epfw7Epididymal fat weight QTL 720.660.001epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)54946360094463600Rat
7411561Bw134Body weight QTL 134240.001body mass (VT:0001259)body weight gain (CMO:0000420)54946360094463600Rat
1576312Emca8Estrogen-induced mammary cancer QTL 84.1mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)550328551141643988Rat
2303615Vencon7Ventilatory control QTL 70.001respiration trait (VT:0001943)respiration rate (CMO:0000289)55098389595983895Rat
2303574Gluco42Glucose level QTL 422blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)55349671998496719Rat
61359EaexExperimental allergic encephalomyelitis QTL x3nervous system integrity trait (VT:0010566)post-insult time to onset of experimental autoimmune encephalomyelitis (CMO:0001422)555715622100715622Rat
70189Mcs5Mammary carcinoma susceptibility QTL 510.51mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)555805606132207589Rat
1358895Bp254Blood pressure QTL 2543.60.0003arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)558829236128034027Rat
61426Scl2Serum cholesterol level QTL 27.30.001blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)559793399143070159Rat
2316954Rf57Renal function QTL 570kidney glomerulus morphology trait (VT:0005325)index of glomerular damage (CMO:0001135)55979352890450144Rat
2316957Pur21Proteinuria QTL 216.2urine protein amount (VT:0005160)urine protein level (CMO:0000591)559793528113558156Rat
61386Bp49Blood pressure QTL 4916.6cerebrum integrity trait (VT:0010549)brain infarction volume (CMO:0001013)56029343498603051Rat
61393Bp7Blood pressure QTL 74.50.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)560293434161481680Rat
2290005Mcs24Mammary carcinoma susceptibility QTL 24mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)564719390109719390Rat
2306971Anxrr21Anxiety related response QTL 219.47fear/anxiety-related behavior trait (VT:1000241)number of entries into a discrete space in an experimental apparatus (CMO:0000960)566174080124160948Rat
2312671Scl64Serum cholesterol level QTL 640.001blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)568984307104251008Rat
61380Edpm5Estrogen-dependent pituitary mass QTL 54.50.92pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)568984307104251008Rat
1357396Bw44Body weight QTL 444.19body mass (VT:0001259)body weight (CMO:0000012)568984307104251008Rat
1357402Bw46Body weight QTL 464.47body mass (VT:0001259)body mass index (BMI) (CMO:0000105)568984307104251008Rat
2302381Bw84Body weight QTL 844.47body mass (VT:0001259)body mass index (BMI) (CMO:0000105)568984307104251008Rat
1354598Srn6Serum renin concentration QTL 63.8blood renin amount (VT:0003349)plasma renin activity level (CMO:0000116)569540295151018848Rat
1298070Scl18Serum cholesterol level QTL 183.7blood LDL cholesterol amount (VT:0000181)calculated plasma low density lipoprotein cholesterol level (CMO:0001245)579584860124584860Rat
1598846Bp293Blood pressure QTL 2933.9arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)579584860124584860Rat
1598859Cm66Cardiac mass QTL 662heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)579584860124584860Rat
1302790Scl20Serum cholesterol level QTL 206.40.0001blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)582394392166664054Rat
1331782Rf36Renal function QTL 363.296kidney blood vessel physiology trait (VT:0100012)absolute change in renal blood flow rate (CMO:0001168)58384059897059958Rat
1298086Bp156Blood pressure QTL 156arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)584132602129132602Rat
7411601Foco12Food consumption QTL 1219.70.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)587468046132468046Rat
7411564Bw135Body weight QTL 1350.001body mass (VT:0001259)body weight gain (CMO:0000420)587468046132468046Rat
7411582Foco3Food consumption QTL 37.50.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)587468046132468046Rat
6903316Bw113Body weight QTL 11320.0103body mass (VT:0001259)body weight (CMO:0000012)587765973132765973Rat
1358889Bp261Blood pressure QTL 2612.86arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)590067849128034027Rat
1358909Kidm25Kidney mass QTL 251.87kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)590067849128034027Rat
631527Tls1T-lymphoma susceptibility QTL 100.001thymus integrity trait (VT:0010555)post-insult time to onset of T-cell lymphoma (CMO:0001907)590450144135450144Rat

Markers in Region
D5Rat107  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2590,405,302 - 90,405,423 (+)MAPPERmRatBN7.2
Rnor_6.0593,227,981 - 93,228,101NCBIRnor6.0
Rnor_5.0597,270,362 - 97,270,482UniSTSRnor5.0
RGSC_v3.4594,470,752 - 94,470,873RGDRGSC3.4
RGSC_v3.4594,470,753 - 94,470,873UniSTSRGSC3.4
RGSC_v3.1594,475,866 - 94,475,986RGD
Celera589,089,638 - 89,089,758UniSTS
RH 3.4 Map5701.0RGD
RH 3.4 Map5701.0UniSTS
RH 2.0 Map5565.6RGD
SHRSP x BN Map551.3999RGD
Cytogenetic Map5q31UniSTS
BE097842  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2590,263,544 - 90,263,763 (+)MAPPERmRatBN7.2
Rnor_6.0593,081,022 - 93,081,240NCBIRnor6.0
Rnor_5.0597,123,917 - 97,124,135UniSTSRnor5.0
RGSC_v3.4594,328,091 - 94,328,309UniSTSRGSC3.4
Celera588,947,981 - 88,948,199UniSTS
RH 3.4 Map5696.9UniSTS
Cytogenetic Map5q31UniSTS
AI703917  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2590,240,196 - 90,240,412 (+)MAPPERmRatBN7.2
Rnor_6.0593,058,206 - 93,058,421NCBIRnor6.0
Rnor_5.0597,100,865 - 97,101,080UniSTSRnor5.0
RGSC_v3.4594,080,181 - 94,080,396UniSTSRGSC3.4
Celera588,924,532 - 88,924,747UniSTS
RH 3.4 Map5696.9UniSTS
Cytogenetic Map5q31UniSTS
RH142256  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2590,048,601 - 90,048,779 (+)MAPPERmRatBN7.2
Rnor_6.0592,863,838 - 92,864,015NCBIRnor6.0
Rnor_5.0596,908,932 - 96,909,109UniSTSRnor5.0
RGSC_v3.4594,284,871 - 94,285,048UniSTSRGSC3.4
Celera588,730,011 - 88,730,190UniSTS
RH 3.4 Map5692.1UniSTS
Cytogenetic Map5q31UniSTS
BF410120  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2590,166,521 - 90,166,760 (+)MAPPERmRatBN7.2
Rnor_6.0592,982,495 - 92,982,733NCBIRnor6.0
Rnor_5.0597,026,961 - 97,027,199UniSTSRnor5.0
RGSC_v3.4594,165,897 - 94,166,135UniSTSRGSC3.4
Celera588,847,833 - 88,848,071UniSTS
RH 3.4 Map1909.29UniSTS
Cytogenetic Map5q31UniSTS
RH135104  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2590,050,283 - 90,050,472 (+)MAPPERmRatBN7.2
Rnor_6.0592,865,520 - 92,865,708NCBIRnor6.0
Rnor_5.0596,910,614 - 96,910,802UniSTSRnor5.0
RGSC_v3.4594,283,178 - 94,283,366UniSTSRGSC3.4
Celera588,731,695 - 88,731,883UniSTS
RH 3.4 Map5692.1UniSTS
Cytogenetic Map5q31UniSTS
RH138901  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2590,049,295 - 90,049,484 (+)MAPPERmRatBN7.2
Rnor_6.0592,864,532 - 92,864,720NCBIRnor6.0
Rnor_5.0596,909,626 - 96,909,814UniSTSRnor5.0
RGSC_v3.4594,284,166 - 94,284,354UniSTSRGSC3.4
Celera588,730,707 - 88,730,895UniSTS
RH 3.4 Map5692.1UniSTS
Cytogenetic Map5q31UniSTS
PTPRD  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2590,060,612 - 90,061,733 (+)MAPPERmRatBN7.2
Rnor_6.0592,875,847 - 92,876,967NCBIRnor6.0
Rnor_5.0596,920,941 - 96,922,061UniSTSRnor5.0
RGSC_v3.4594,271,919 - 94,273,039UniSTSRGSC3.4
Celera588,742,018 - 88,743,142UniSTS
Cytogenetic Map5q31UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 2 35 34 25 2 25 2 2 74 35 34 11 2
Low 1 8 23 16 17 16 6 8 7 6
Below cutoff 1

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001427220 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039111437 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039111440 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039111451 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039111453 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039111455 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039111456 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039111459 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039111461 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039111462 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039111463 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063288538 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063288539 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063288540 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063288541 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063288542 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063288543 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063288544 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063288545 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063288546 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063288547 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063288548 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063288549 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063288550 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063288551 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063288552 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063288553 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063288554 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063288555 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063288556 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063288557 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063288559 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063288560 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063288561 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063288562 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063288564 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063288565 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063288566 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063288567 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063288568 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063288569 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063288570 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063288571 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063288572 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063288573 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063288574 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide CH473978 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAXUCZ010000005 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  U57502 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

RefSeq Acc Id: ENSRNOT00000075474   ⟹   ENSRNOP00000066744
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl590,048,966 - 90,341,310 (-)Ensembl
Rnor_6.0 Ensembl592,862,267 - 93,244,202 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000094348   ⟹   ENSRNOP00000089430
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl590,048,966 - 92,369,396 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000110800   ⟹   ENSRNOP00000085531
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl590,048,966 - 90,550,297 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000113220   ⟹   ENSRNOP00000086806
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl590,048,966 - 90,550,297 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000115119   ⟹   ENSRNOP00000080613
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl590,048,966 - 90,893,576 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000119354   ⟹   ENSRNOP00000091521
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl590,048,966 - 90,527,316 (-)Ensembl
RefSeq Acc Id: XM_039111437   ⟹   XP_038967365
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8595,093,221 - 97,415,498 (-)NCBI
mRatBN7.2590,049,220 - 90,698,977 (-)NCBI
RefSeq Acc Id: XM_039111440   ⟹   XP_038967368
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8595,093,221 - 97,415,498 (-)NCBI
mRatBN7.2590,049,220 - 90,698,977 (-)NCBI
RefSeq Acc Id: XM_039111451   ⟹   XP_038967379
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8595,093,221 - 97,415,498 (-)NCBI
mRatBN7.2590,049,220 - 90,698,977 (-)NCBI
RefSeq Acc Id: XM_039111453   ⟹   XP_038967381
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8595,093,221 - 97,415,498 (-)NCBI
mRatBN7.2590,049,220 - 90,698,977 (-)NCBI
RefSeq Acc Id: XM_039111455   ⟹   XP_038967383
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8595,093,221 - 97,415,498 (-)NCBI
mRatBN7.2590,049,220 - 90,698,977 (-)NCBI
RefSeq Acc Id: XM_039111456   ⟹   XP_038967384
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8595,093,221 - 97,415,498 (-)NCBI
mRatBN7.2590,049,220 - 90,698,977 (-)NCBI
RefSeq Acc Id: XM_039111459   ⟹   XP_038967387
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8595,093,221 - 97,415,498 (-)NCBI
mRatBN7.2590,049,220 - 90,698,977 (-)NCBI
RefSeq Acc Id: XM_039111461   ⟹   XP_038967389
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8595,093,221 - 97,415,498 (-)NCBI
mRatBN7.2590,049,220 - 90,698,977 (-)NCBI
RefSeq Acc Id: XM_039111462   ⟹   XP_038967390
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8595,093,221 - 97,415,498 (-)NCBI
mRatBN7.2590,049,220 - 90,698,977 (-)NCBI
RefSeq Acc Id: XM_039111463   ⟹   XP_038967391
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8595,093,221 - 97,415,498 (-)NCBI
mRatBN7.2590,046,993 - 90,421,239 (-)NCBI
RefSeq Acc Id: XM_063288538   ⟹   XP_063144608
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8595,093,221 - 97,415,498 (-)NCBI
RefSeq Acc Id: XM_063288539   ⟹   XP_063144609
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8595,093,221 - 97,415,498 (-)NCBI
RefSeq Acc Id: XM_063288540   ⟹   XP_063144610
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8595,093,221 - 97,415,498 (-)NCBI
RefSeq Acc Id: XM_063288541   ⟹   XP_063144611
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8595,093,221 - 95,483,931 (-)NCBI
RefSeq Acc Id: XM_063288542   ⟹   XP_063144612
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8595,093,221 - 97,415,498 (-)NCBI
RefSeq Acc Id: XM_063288543   ⟹   XP_063144613
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8595,093,221 - 97,415,498 (-)NCBI
RefSeq Acc Id: XM_063288544   ⟹   XP_063144614
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8595,093,221 - 97,415,498 (-)NCBI
RefSeq Acc Id: XM_063288545   ⟹   XP_063144615
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8595,093,221 - 97,415,498 (-)NCBI
RefSeq Acc Id: XM_063288546   ⟹   XP_063144616
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8595,093,221 - 97,415,498 (-)NCBI
RefSeq Acc Id: XM_063288547   ⟹   XP_063144617
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8595,093,221 - 97,415,498 (-)NCBI
RefSeq Acc Id: XM_063288548   ⟹   XP_063144618
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8595,093,221 - 97,415,498 (-)NCBI
RefSeq Acc Id: XM_063288549   ⟹   XP_063144619
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8595,093,221 - 97,415,498 (-)NCBI
RefSeq Acc Id: XM_063288550   ⟹   XP_063144620
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8595,093,221 - 97,415,498 (-)NCBI
RefSeq Acc Id: XM_063288551   ⟹   XP_063144621
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8595,093,221 - 97,415,498 (-)NCBI
RefSeq Acc Id: XM_063288552   ⟹   XP_063144622
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8595,093,221 - 97,415,498 (-)NCBI
RefSeq Acc Id: XM_063288553   ⟹   XP_063144623
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8595,093,221 - 97,415,498 (-)NCBI
RefSeq Acc Id: XM_063288554   ⟹   XP_063144624
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8595,093,221 - 97,415,498 (-)NCBI
RefSeq Acc Id: XM_063288555   ⟹   XP_063144625
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8595,093,221 - 97,415,498 (-)NCBI
RefSeq Acc Id: XM_063288556   ⟹   XP_063144626
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8595,093,221 - 97,415,498 (-)NCBI
RefSeq Acc Id: XM_063288557   ⟹   XP_063144627
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8595,093,221 - 97,415,498 (-)NCBI
RefSeq Acc Id: XM_063288559   ⟹   XP_063144629
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8595,093,221 - 97,415,498 (-)NCBI
RefSeq Acc Id: XM_063288560   ⟹   XP_063144630
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8595,093,221 - 97,415,498 (-)NCBI
RefSeq Acc Id: XM_063288561   ⟹   XP_063144631
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8595,093,221 - 97,415,498 (-)NCBI
RefSeq Acc Id: XM_063288562   ⟹   XP_063144632
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8595,093,221 - 97,415,498 (-)NCBI
RefSeq Acc Id: XM_063288564   ⟹   XP_063144634
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8595,093,221 - 97,415,498 (-)NCBI
RefSeq Acc Id: XM_063288565   ⟹   XP_063144635
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8595,093,221 - 97,415,498 (-)NCBI
RefSeq Acc Id: XM_063288566   ⟹   XP_063144636
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8595,093,221 - 97,415,498 (-)NCBI
RefSeq Acc Id: XM_063288567   ⟹   XP_063144637
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8595,093,221 - 97,415,498 (-)NCBI
RefSeq Acc Id: XM_063288568   ⟹   XP_063144638
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8595,093,221 - 97,415,498 (-)NCBI
RefSeq Acc Id: XM_063288569   ⟹   XP_063144639
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8595,093,221 - 97,415,498 (-)NCBI
RefSeq Acc Id: XM_063288570   ⟹   XP_063144640
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8595,093,221 - 97,415,498 (-)NCBI
RefSeq Acc Id: XM_063288571   ⟹   XP_063144641
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8595,093,221 - 97,415,498 (-)NCBI
RefSeq Acc Id: XM_063288572   ⟹   XP_063144642
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8595,093,221 - 97,415,498 (-)NCBI
RefSeq Acc Id: XM_063288573   ⟹   XP_063144643
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8595,093,221 - 97,415,498 (-)NCBI
RefSeq Acc Id: XM_063288574   ⟹   XP_063144644
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8595,093,221 - 97,415,498 (-)NCBI
Protein Sequences
Protein RefSeqs NP_001414149 (Get FASTA)   NCBI Sequence Viewer  
  XP_038967365 (Get FASTA)   NCBI Sequence Viewer  
  XP_038967368 (Get FASTA)   NCBI Sequence Viewer  
  XP_038967379 (Get FASTA)   NCBI Sequence Viewer  
  XP_038967381 (Get FASTA)   NCBI Sequence Viewer  
  XP_038967383 (Get FASTA)   NCBI Sequence Viewer  
  XP_038967384 (Get FASTA)   NCBI Sequence Viewer  
  XP_038967387 (Get FASTA)   NCBI Sequence Viewer  
  XP_038967389 (Get FASTA)   NCBI Sequence Viewer  
  XP_038967390 (Get FASTA)   NCBI Sequence Viewer  
  XP_038967391 (Get FASTA)   NCBI Sequence Viewer  
  XP_063144608 (Get FASTA)   NCBI Sequence Viewer  
  XP_063144609 (Get FASTA)   NCBI Sequence Viewer  
  XP_063144610 (Get FASTA)   NCBI Sequence Viewer  
  XP_063144611 (Get FASTA)   NCBI Sequence Viewer  
  XP_063144612 (Get FASTA)   NCBI Sequence Viewer  
  XP_063144613 (Get FASTA)   NCBI Sequence Viewer  
  XP_063144614 (Get FASTA)   NCBI Sequence Viewer  
  XP_063144615 (Get FASTA)   NCBI Sequence Viewer  
  XP_063144616 (Get FASTA)   NCBI Sequence Viewer  
  XP_063144617 (Get FASTA)   NCBI Sequence Viewer  
  XP_063144618 (Get FASTA)   NCBI Sequence Viewer  
  XP_063144619 (Get FASTA)   NCBI Sequence Viewer  
  XP_063144620 (Get FASTA)   NCBI Sequence Viewer  
  XP_063144621 (Get FASTA)   NCBI Sequence Viewer  
  XP_063144622 (Get FASTA)   NCBI Sequence Viewer  
  XP_063144623 (Get FASTA)   NCBI Sequence Viewer  
  XP_063144624 (Get FASTA)   NCBI Sequence Viewer  
  XP_063144625 (Get FASTA)   NCBI Sequence Viewer  
  XP_063144626 (Get FASTA)   NCBI Sequence Viewer  
  XP_063144627 (Get FASTA)   NCBI Sequence Viewer  
  XP_063144629 (Get FASTA)   NCBI Sequence Viewer  
  XP_063144630 (Get FASTA)   NCBI Sequence Viewer  
  XP_063144631 (Get FASTA)   NCBI Sequence Viewer  
  XP_063144632 (Get FASTA)   NCBI Sequence Viewer  
  XP_063144634 (Get FASTA)   NCBI Sequence Viewer  
  XP_063144635 (Get FASTA)   NCBI Sequence Viewer  
  XP_063144636 (Get FASTA)   NCBI Sequence Viewer  
  XP_063144637 (Get FASTA)   NCBI Sequence Viewer  
  XP_063144638 (Get FASTA)   NCBI Sequence Viewer  
  XP_063144639 (Get FASTA)   NCBI Sequence Viewer  
  XP_063144640 (Get FASTA)   NCBI Sequence Viewer  
  XP_063144641 (Get FASTA)   NCBI Sequence Viewer  
  XP_063144642 (Get FASTA)   NCBI Sequence Viewer  
  XP_063144643 (Get FASTA)   NCBI Sequence Viewer  
  XP_063144644 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAB02007 (Get FASTA)   NCBI Sequence Viewer  
  EDM10485 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000066744.3
  ENSRNOP00000080613.1
  ENSRNOP00000085531
  ENSRNOP00000085531.1
  ENSRNOP00000086806.1
  ENSRNOP00000089430.1
  ENSRNOP00000091521.1
RefSeq Acc Id: ENSRNOP00000066744   ⟸   ENSRNOT00000075474
RefSeq Acc Id: XP_038967391   ⟸   XM_039111463
- Peptide Label: isoform X4
- UniProtKB: A0A8I6A6R5 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038967390   ⟸   XM_039111462
- Peptide Label: isoform X42
- UniProtKB: A0A8I6A789 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038967389   ⟸   XM_039111461
- Peptide Label: isoform X40
- UniProtKB: A0A8I5ZQN2 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038967368   ⟸   XM_039111440
- Peptide Label: isoform X20
- UniProtKB: A0A8I6AEM0 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038967387   ⟸   XM_039111459
- Peptide Label: isoform X39
- UniProtKB: A0A8I5ZQN2 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038967381   ⟸   XM_039111453
- Peptide Label: isoform X34
- UniProtKB: A0A8I5ZQN2 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038967384   ⟸   XM_039111456
- Peptide Label: isoform X37
- UniProtKB: A0A8I5ZQN2 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038967383   ⟸   XM_039111455
- Peptide Label: isoform X36
- UniProtKB: A0A8I5ZQN2 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038967379   ⟸   XM_039111451
- Peptide Label: isoform X33
- UniProtKB: A0A8I5ZQN2 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038967365   ⟸   XM_039111437
- Peptide Label: isoform X14
- UniProtKB: A0A8I6A1V1 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSRNOP00000089430   ⟸   ENSRNOT00000094348
RefSeq Acc Id: ENSRNOP00000080613   ⟸   ENSRNOT00000115119
RefSeq Acc Id: ENSRNOP00000085531   ⟸   ENSRNOT00000110800
RefSeq Acc Id: ENSRNOP00000091521   ⟸   ENSRNOT00000119354
RefSeq Acc Id: ENSRNOP00000086806   ⟸   ENSRNOT00000113220
RefSeq Acc Id: XP_063144609   ⟸   XM_063288539
- Peptide Label: isoform X1
- UniProtKB: A0A8I6A6R5 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063144610   ⟸   XM_063288540
- Peptide Label: isoform X1
- UniProtKB: A0A8I6A6R5 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063144644   ⟸   XM_063288574
- Peptide Label: isoform X41
- UniProtKB: A0A8I6A789 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063144636   ⟸   XM_063288566
- Peptide Label: isoform X27
- UniProtKB: A0A8I6AEM0 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063144635   ⟸   XM_063288565
- Peptide Label: isoform X26
- UniProtKB: A0A8I6A6R5 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063144634   ⟸   XM_063288564
- Peptide Label: isoform X25
- UniProtKB: A0A8I6A6R5 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063144629   ⟸   XM_063288559
- Peptide Label: isoform X21
- UniProtKB: A0A8I6AEM0 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063144624   ⟸   XM_063288554
- Peptide Label: isoform X16
- UniProtKB: A0A8I6A6R5 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063144623   ⟸   XM_063288553
- Peptide Label: isoform X15
- UniProtKB: A0A8I6A6R5 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063144626   ⟸   XM_063288556
- Peptide Label: isoform X18
- UniProtKB: A6J821 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063144620   ⟸   XM_063288550
- Peptide Label: isoform X11
- UniProtKB: A0A8I6A6R5 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063144618   ⟸   XM_063288548
- Peptide Label: isoform X9
- UniProtKB: A0A8I6A6R5 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063144632   ⟸   XM_063288562
- Peptide Label: isoform X24
- UniProtKB: A0A8I6A6R5 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063144631   ⟸   XM_063288561
- Peptide Label: isoform X23
- UniProtKB: A0A8I6A6R5 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063144614   ⟸   XM_063288544
- Peptide Label: isoform X5
- UniProtKB: A0A8I6A6R5 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063144641   ⟸   XM_063288571
- Peptide Label: isoform X32
- UniProtKB: A0A8I6A789 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063144643   ⟸   XM_063288573
- Peptide Label: isoform X38
- UniProtKB: A0A8I5ZQN2 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063144627   ⟸   XM_063288557
- Peptide Label: isoform X19
- UniProtKB: A0A8I6AEM0 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063144616   ⟸   XM_063288546
- Peptide Label: isoform X7
- UniProtKB: A0A8I6A6R5 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063144640   ⟸   XM_063288570
- Peptide Label: isoform X31
- UniProtKB: A0A8I6A789 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063144638   ⟸   XM_063288568
- Peptide Label: isoform X29
- UniProtKB: A0A8I6A789 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063144642   ⟸   XM_063288572
- Peptide Label: isoform X35
- UniProtKB: A0A8I5ZQN2 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063144639   ⟸   XM_063288569
- Peptide Label: isoform X30
- UniProtKB: A0A8I6A789 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063144637   ⟸   XM_063288567
- Peptide Label: isoform X28
- UniProtKB: A0A8I6A789 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063144630   ⟸   XM_063288560
- Peptide Label: isoform X22
- UniProtKB: A0A8I6A6R5 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063144625   ⟸   XM_063288555
- Peptide Label: isoform X17
- UniProtKB: A0A8I6AEM0 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063144619   ⟸   XM_063288549
- Peptide Label: isoform X10
- UniProtKB: A0A8I6A6R5 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063144617   ⟸   XM_063288547
- Peptide Label: isoform X8
- UniProtKB: A0A8I6A6R5 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063144612   ⟸   XM_063288542
- Peptide Label: isoform X2
- UniProtKB: A0A8I6A6R5 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063144613   ⟸   XM_063288543
- Peptide Label: isoform X3
- UniProtKB: A0A8I6A6R5 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063144622   ⟸   XM_063288552
- Peptide Label: isoform X13
- UniProtKB: A0A8I6A1V1 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063144615   ⟸   XM_063288545
- Peptide Label: isoform X6
- UniProtKB: A0A8I6A6R5 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063144621   ⟸   XM_063288551
- Peptide Label: isoform X12
- UniProtKB: A0A8I6A1V1 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063144608   ⟸   XM_063288538
- Peptide Label: isoform X1
- UniProtKB: A0A8I6A6R5 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063144611   ⟸   XM_063288541
- Peptide Label: isoform X1
- UniProtKB: A0A8I6A6R5 (UniProtKB/TrEMBL)
Protein Domains
Fibronectin type-III   Ig-like   Tyrosine specific protein phosphatases   Tyrosine-protein phosphatase

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-M0RB22-F1-model_v2 AlphaFold M0RB22 1-1937 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1561090 AgrOrtholog
BioCyc Gene G2FUF-40954 BioCyc
Ensembl Genes ENSRNOG00000005711 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000075474.4 UniProtKB/TrEMBL
  ENSRNOT00000094348.1 UniProtKB/TrEMBL
  ENSRNOT00000110800.1 UniProtKB/TrEMBL
  ENSRNOT00000113220.1 UniProtKB/TrEMBL
  ENSRNOT00000115119.1 UniProtKB/TrEMBL
  ENSRNOT00000119354.1 UniProtKB/TrEMBL
Gene3D-CATH 2.60.40.10 UniProtKB/TrEMBL
  3.90.190.10 UniProtKB/TrEMBL
InterPro Fibronectin_type3 UniProtKB/TrEMBL
  FN3_sf UniProtKB/TrEMBL
  Ig-like_dom UniProtKB/TrEMBL
  Ig-like_dom_sf UniProtKB/TrEMBL
  Ig-like_fold UniProtKB/TrEMBL
  Ig_I-set UniProtKB/TrEMBL
  Ig_sub UniProtKB/TrEMBL
  Ig_sub2 UniProtKB/TrEMBL
  Prot-tyrosine_phosphatase-like UniProtKB/TrEMBL
  R-PTP-delta_cat UniProtKB/TrEMBL
  Tyr/Dual-sp_Pase UniProtKB/TrEMBL
  Tyr_Pase_AS UniProtKB/TrEMBL
  Tyr_Pase_cat UniProtKB/TrEMBL
  Tyr_Pase_rcpt/non-rcpt UniProtKB/TrEMBL
NCBI Gene 313278 ENTREZGENE
PANTHER BROTHER OF IHOG, ISOFORM G-RELATED UniProtKB/TrEMBL
  CYTOKINE RECEPTOR UniProtKB/TrEMBL
  MYOPALLADIN UniProtKB/TrEMBL
  PROTEIN SIDEKICK UniProtKB/TrEMBL
  PROTEIN TYROSINE PHOSPHATASE RECEPTOR TYPE S UniProtKB/TrEMBL
Pfam fn3 UniProtKB/TrEMBL
  I-set UniProtKB/TrEMBL
  Ig_3 UniProtKB/TrEMBL
  Y_phosphatase UniProtKB/TrEMBL
PhenoGen Ptprd PhenoGen
PRINTS FNTYPEIII UniProtKB/TrEMBL
  PRTYPHPHTASE UniProtKB/TrEMBL
PROSITE FN3 UniProtKB/TrEMBL
  IG_LIKE UniProtKB/TrEMBL
  PROKAR_LIPOPROTEIN UniProtKB/TrEMBL
  TYR_PHOSPHATASE_1 UniProtKB/TrEMBL
  TYR_PHOSPHATASE_2 UniProtKB/TrEMBL
  TYR_PHOSPHATASE_PTP UniProtKB/TrEMBL
RatGTEx ENSRNOG00000005711 RatGTEx
SMART FN3 UniProtKB/TrEMBL
  IGc2 UniProtKB/TrEMBL
  PTPc UniProtKB/TrEMBL
  PTPc_motif UniProtKB/TrEMBL
  SM00409 UniProtKB/TrEMBL
Superfamily-SCOP FN_III-like UniProtKB/TrEMBL
  SSF48726 UniProtKB/TrEMBL
  SSF52799 UniProtKB/TrEMBL
UniProt A0A8I5ZQN2 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6A1V1 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6A6R5 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6A789 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6AEM0 ENTREZGENE, UniProtKB/TrEMBL
  A6J821 ENTREZGENE, UniProtKB/TrEMBL
  A6KQX6_RAT UniProtKB/TrEMBL
  A6KQX7_RAT UniProtKB/TrEMBL
  A6KQY0_RAT UniProtKB/TrEMBL
  A6KQY2_RAT UniProtKB/TrEMBL
  A6KQY3_RAT UniProtKB/TrEMBL
  M0RB22_RAT UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2021-03-09 Ptprd  protein tyrosine phosphatase, receptor type, D  LOC103692382  uncharacterized LOC103692382  Data merged from RGD:9358592 737654 PROVISIONAL
2014-08-25 LOC103692382  uncharacterized LOC103692382      Symbol and Name status set to provisional 70820 PROVISIONAL
2009-04-29 Ptprd  protein tyrosine phosphatase, receptor type, D  RGD1561090  similar to protein tyrosine phosphatase, receptor type, D   Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-04-30 RGD1561090  similar to protein tyrosine phosphatase, receptor type, D   RGD1561090_predicted  similar to protein tyrosine phosphatase, receptor type, D (predicted)  'predicted' is removed 2292626 APPROVED
2006-03-07 RGD1561090_predicted  similar to protein tyrosine phosphatase, receptor type, D (predicted)  LOC313278  similar to protein tyrosine phosphatase, receptor type, D  Symbol and Name status set to approved 1299863 APPROVED
2006-02-09 LOC313278  similar to protein tyrosine phosphatase, receptor type, D      Symbol and Name status set to provisional 70820 PROVISIONAL